Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

Immunity

Volumn 29, Issue 1, 2008, Pages 114-126

  Curotto de Lafaille, Maria A ^a   Kutchukhidze, Nino ^a   Shen, Shiqian ^a   Ding, Yi ^a   Yee, Herman ^a   Lafaille, Juan J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CELLIMMUNOL

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 5; TRANSCRIPTION FACTOR FOXP3;

ADAPTIVE IMMUNITY; ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CYTOKINE PRODUCTION; EOSINOPHILIA; IMMUNOLOGICAL TOLERANCE; MOUSE; MUCOSA INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SENSITIZATION;

ANIMALS; CELL DIFFERENTIATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; IMMUNITY, MUCOSAL; INFLAMMATION; INTESTINAL MUCOSA; MICE; MICE, MUTANT STRAINS; MUTATION; OVALBUMIN; POLYMERASE CHAIN REACTION; RESPIRATORY HYPERSENSITIVITY; RESPIRATORY MUCOSA; T-LYMPHOCYTES, REGULATORY;

EID: 46749126890     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2008.05.010     Document Type: Article

References (51)

1. Aloisi F., and Pujol-Borrell R. Lymphoid neogenesis in chronic inflammatory diseases. Nat. Rev. Immunol. 6 (2006) 205-217
2. Annacker O., Pimenta-Araujo R., Burlen-Defranoux O., Barbosa T.C., Cumano A., and Bandeira A. CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J. Immunol. 166 (2001) 3008-3018
3. Apostolou I., and von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199 (2004) 1401-1408
4. Bennett C.L., Christie J., Ramsdell F., Brunkow M.E., Ferguson P.J., Whitesell L., Kelly T.E., Saulsbury F.T., Chance P.F., and Ochs H.D. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27 (2001) 20-21
5. Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., Weiner H.L., and Kuchroo V.K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441 (2006) 235-238
6. Carrier Y., Yuan J., Kuchroo V.K., and Weiner H.L. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice. J. Immunol. 178 (2007) 179-185
7. Chatila T.A., Blaeser F., Ho N., Lederman H.M., Voulgaropoulos C., Helms C., and Bowcock A.M. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106 (2000) R75-R81
8. Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., McGrady G., and Wahl S.M. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198 (2003) 1875-1886
9. Cobbold S.P., Castejon R., Adams E., Zelenika D., Graca L., Humm S., and Waldmann H. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol. 172 (2004) 6003-6010
10. Cohn L., Elias J.A., and Chupp G.L. Asthma: Mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22 (2004) 789-815
11. Coombes J.L., Siddiqui K.R., Arancibia-Carcamo C.V., Hall J., Sun C.M., Belkaid Y., and Powrie F. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 204 (2007) 1757-1764
12. Curotto de Lafaille M.A., Lino A.C., Kutchukhidze N., and Lafaille J.J. CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion. J. Immunol. 173 (2004) 7259-7268
13. Curotto de Lafaille M.A., Muriglan S., Sunshine M.J., Lei Y., Kutchukhidze N., Furtado G.C., Wensky A.K., Olivares-Villagomez D., and Lafaille J.J. Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes. J. Exp. Med. 194 (2001) 1349-1359
14. Denning T.L., Wang Y.C., Patel S.R., Williams I.R., and Pulendran B. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat. Immunol. 8 (2007) 1086-1094
15. Drayton D.L., Liao S., Mounzer R.H., and Ruddle N.H. Lymphoid organ development: from ontogeny to neogenesis. Nat. Immunol. 7 (2006) 344-353
16. Erazo A., Kutchukhidze N., Leung M., Christ A.P., Urban Jr. J.F., Curotto de Lafaille M.A., and Lafaille J.J. Unique maturation program of the IgE response in vivo. Immunity 26 (2007) 191-203
17. Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4 (2003) 330-336
18. Fukaura H., Kent S.C., Pietrusewicz M.J., Khoury S.J., Weiner H.L., and Hafler D.A. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J. Clin. Invest. 98 (1996) 70-77
19. Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
20. Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., Cua D.J., and Littman D.R. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126 (2006) 1121-1133
21. Iwamoto I., Nakajima H., Endo H., and Yoshida S. Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells. J. Exp. Med. 177 (1993) 573-576
22. Iweala O.I., and Nagler C.R. Immune privilege in the gut: The establishment and maintenance of non-responsiveness to dietary antigens and commensal flora. Immunol. Rev. 213 (2006) 82-100
23. Kanangat S., Blair P., Reddy R., Daheshia M., Godfrey V., Rouse B.T., and Wilkinson E. Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes. Eur. J. Immunol. 26 (1996) 161-165
24. Khattri R., Cox T., Yasayko S.A., and Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4 (2003) 337-342
25. Klein L., Khazaie K., and von Boehmer H. In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc. Natl. Acad. Sci. USA 100 (2003) 8886-8891
26. Korn T., Reddy J., Gao W., Bettelli E., Awasthi A., Petersen T.R., Backstrom B.T., Sobel R.A., Wucherpfennig K.W., Strom T.B., et al. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat. Med. 13 (2007) 423-431
27. Lafaille J.J., Nagashima K., Katsuki M., and Tonegawa S. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78 (1994) 399-408
28. Levings M.K., Gregori S., Tresoldi E., Cazzaniga S., Bonini C., and Roncarolo M.G. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood 105 (2005) 1162-1169
29. Lewkowich I.P., Herman N.S., Schleifer K.W., Dance M.P., Chen B.L., Dienger K.M., Sproles A.A., Shah J.S., Kohl J., Belkaid Y., and Wills-Karp M. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J. Exp. Med. 202 (2005) 1549-1561
30. Lin W., Truong N., Grossman W.J., Haribhai D., Williams C.B., Wang J., Martin M.G., and Chatila T.A. Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice. J. Allergy Clin. Immunol. 116 (2005) 1106-1115
31. Moyron-Quiroz J., Rangel-Moreno J., Carragher D.M., and Randall T.D. The function of local lymphoid tissues in pulmonary immune responses. Adv. Exp. Med. Biol. 590 (2007) 55-68
32. Mucida D., Kutchukhidze N., Erazo A., Russo M., Lafaille J.J., and Curotto de Lafaille M.A. Oral tolerance in the absence of naturally occurring Tregs. J. Clin. Invest. 115 (2005) 1923-1933
33. Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., and Cheroutre H. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 317 (2007) 256-260
34. Olivares-Villagomez D., Wang Y., and Lafaille J.J. Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J. Exp. Med. 188 (1998) 1883-1894
35. Ruprecht C.R., Gattorno M., Ferlito F., Gregorio A., Martini A., Lanzavecchia A., and Sallusto F. Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. J. Exp. Med. 201 (2005) 1793-1803
36. Saruta M., Yu Q.T., Fleshner P.R., Mantel P.Y., Schmidt-Weber C.B., Banham A.H., and Papadakis K.A. Characterization of FOXP3(+)CD4(+) regulatory T cells in Crohn's disease. Clin. Immunol. 125 (2007) 281-290
37. Sasaki M., Ikeda H., Sawada S., Sato Y., and Nakanuma Y. Naturally-occurring regulatory T cells are increased in inflamed portal tracts with cholangiopathy in primary biliary cirrhosis. J. Clin. Pathol. 60 (2007) 1102-1107
38. Schmitz J., Owyang A., Oldham E., Song Y., Murphy E., McClanahan T.K., Zurawski G., Moshrefi M., Qin J., Li X., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23 (2005) 479-490
39. Shen S., Ding Y., Tadokoro C.E., Olivares-Villagomez D., Camps-Ramirez M., Curotto de Lafaille M.A., and Lafaille J.J. Control of homeostatic proliferation by regulatory T cells. J. Clin. Invest. 115 (2005) 3517-3526
40. Shevach E.M., DiPaolo R.A., Andersson J., Zhao D.M., Stephens G.L., and Thornton A.M. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol. Rev. 212 (2006) 60-73
41. Shinagawa K., and Kojima M. Mouse model of airway remodeling: Strain differences. Am. J. Respir. Crit. Care Med. 168 (2003) 959-967
42. Smyth L.J., Starkey C., Vestbo J., and Singh D. CD4-regulatory cells in COPD patients. Chest 132 (2007) 156-163
43. Strickland D.H., Stumbles P.A., Zosky G.R., Subrata L.S., Thomas J.A., Turner D.J., Sly P.D., and Holt P.G. Reversal of airway hyperresponsiveness by induction of airway mucosal CD4+CD25+ regulatory T cells. J. Exp. Med. 203 (2006) 2649-2660
44. Sun C.M., Hall J.A., Blank R.B., Bouladoux N., Oukka M., Mora J.R., and Belkaid Y. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204 (2007) 1775-1785
45. van Amelsfort J.M., Jacobs K.M., Bijlsma J.W., Lafeber F.P., and Taams L.S. CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: Differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum. 50 (2004) 2775-2785
46. Vieira P.L., Christensen J.R., Minaee S., O'Neill E.J., Barrat F.J., Boonstra A., Barthlott T., Stockinger B., Wraith D.C., and O'Garra A. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J. Immunol. 172 (2004) 5986-5993
47. Walker M.R., Kasprowicz D.J., Gersuk V.H., Benard A., Van Landeghen M., Buckner J.H., and Ziegler S.F. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J. Clin. Invest. 112 (2003) 1437-1443
48. Wensky A., Marcondes M.C., and Lafaille J.J. The role of IFN-gamma in the production of Th2 subpopulations: implications for variable Th2-mediated pathologies in autoimmunity. J. Immunol. 167 (2001) 3074-3081
49. Williams L.M., and Rudensky A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 8 (2007) 277-284
50. Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17 (1999) 255-281
51. Zheng S.G., Wang J., Wang P., Gray J.D., and Horwitz D.A. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J. Immunol. 178 (2007) 2018-2027