Interferon-γ-independent CD8+ T cell-mediated protective anti-malaria immunity elicited by recombinant adenovirus

Parasite Immunology

Volumn 22, Issue 3, 2000, Pages 157-160

  Rodrigues, E G ^a   Claassen, J ^a   Lee, S ^a   Wilson, J M ^b   Nussenzweig, R S ^a   Tsuji, M ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

CD8+ T cells; IFN ; Liver stages; Plasmodium yoelii; Protection; Recombinant adenovirus

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; PARASITE ANTIGEN;

ADENOVIRUS; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; IMMUNIZATION; MALARIA; MOUSE; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; IMMUNIZATION; INTERFERON TYPE II; LIVER; MALARIA; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PLASMODIUM YOELII; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS;

ADENOVIRIDAE; ANIMALIA; PLASMODIUM YOELII; PROTOZOA;

EID: 0034056745     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.2000.00289.x     Document Type: Article

References (16)

1. Briones M.R.S., Tsuji M. & Nussenzweig V.. (1996) The large difference in infectivity for mice of Plasmodium berghei and Plasmodium yoelii sporozoites cannot be correlated with their ability to enter into hepatocytes. Molecular Biological Parasitology 77, 7-17
2. Dalton D.K., Pitts-Meek S., Keshav S. et al. (1993) Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259, 1739-1742
3. Davidson B.L., Allen E.D., Kozarsky K.F., Wilson J.M. & Roessler B.J. (1993) A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nature Genetics 3, 219-223
4. Doolan D.L. & Hoffman S.L. (1999) IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model. Journal of Immunology 163, 884-894
5. Huang S., Hendriks W., Althage A. et al. (1993) Immune response in mice that lack the Interferon-γ receptor. Science 259, 1742-1745
6. Nardin E.H. & Nussenzweig R.S. (1993) T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages. Annual Review of Immunology 11, 687-727
7. Rodrigues M., Cordey A.S., Arreaza G. et al. (1991) CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. International Immunology 3, 579-585
8. Rodrigues M., Nussenzweig R.S. & Zavala F. (1993) The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria. Immunology 80, 1 -5
9. Rodrigues E.G., Zavala F., Eichinger D., Wilson J.M. & Tsuji M. (1997) Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria. Journal of Immunology 158, 1268-1274
10. Rodrigues E.G., Zavala F., Nussenzweig R.S., Wilson J.M. & Tsuji M. (1998) Efficient induction of protective anti-malaria immunity by recombinant adenovirus. Vaccine 19, 1812-1817
11. Schofield L., Villaquiran J., Ferreira A. et al. (1987) Gamma Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites. Nature 330, 664-666
12. Seguin M.C., Klotz F.W., Schneider I. et al. (1994) Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: involvement of interferon gamma and CD8+ T cells. Journal of Experimental Medicine 180, 353-358
13. Tsuji M., Miyahira Y., Nussenzweig R.S. et al. (1995) Development of antimalaria immunity in mice lacking IFN-γ receptor. Journal of Immunology 154, 5338-5344
14. Tsuji M., Mombaerts P., Lefrancois L. et al. (1994) γ/δ T cells contribute to immunity against the liver stages of malaria in α/β T-cell-deficient mice. Proceedings of the National Academy of Sciences of the USA 91, 345-349
15. Weiss W.R., Sedegah M., Beaudoin R.L., Miller L.H. & Good M.F. (1988) CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites. Proceedings of the National Academy of Sciences of the USA 85, 573-576
16. Weiss W.R., Sedegah M., Berzofsky J.A. & Hoffman S.L. (1993) The role of CD4+ T cells in immunity to malaria sporozoites. Journal of Immunology 151, 2690-2698