Regulation of TGF-β response during T cell activation is modulated by IL-10

Journal of Immunology

Volumn 167, Issue 2, 2001, Pages 773-778

  Cottrez, F ^a   Groux, H ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL TYPE; CELLULAR DISTRIBUTION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOREGULATION; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION;

EID: 0035879091     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.2.773     Document Type: Article

References (33)

1. Regulation of immune responses by TGF-β
2. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth
3. Control of CD4 effector fate: Transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion
4. Transforming growth factor-β and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
5. Cutting edge: TGF-β inhibits Th type 2 development through inhibition of GATA-3 expression
6. TGF-β1 down-regulates Th2 development and results in decreased IL-4- induced STAT6 activation and GATA-3 expression
7. + Th1/Th2 T cells
8. TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells
9. TGF-β signal transduction
10. TGF-β signaling by Smad proteins
11. TGF-β signaling from receptors to the nucleus
12. Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis
13. Role of transforming growth factor-β signaling in cancer
14. + T cells
15. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
16. + T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-β
17. + T-cell subset inhibits antigen-specific T cell responses and prevents colitis
18. Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones
19. Analysis of the Vβ specificity of superantigen activation with a rapid and sensitive method using RT-PCR and an automatic DNA analyser
20. Lack of interferon γ receptor β chain and the prevention of interferon γ signaling in Th1 cells
21. Functional characterization of a hybrid human-mouse interferon γ receptor: Evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer
22. Identification and sequence of an accessory factor required for activation of the human interferon γ receptor
23. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
24. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
25. Regulation of the interleukin (IL)- 12β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
26. Selective expression of an interleukin-12 receptor component by human T helper 1 cells
27. Modulation of monocyte type I transforming growth factor-β receptors by inflammatory stimuli
28. Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death
29. Abrogation of TGF-β signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
30. Cytokines: Coordinators of immune and inflammatory responses
31. The transforming growth factor-β family
32. Receptors for transforming growth factor-β
33. Regulatory T cells and inflammatory bowel disease