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Volumn 174, Issue 5, 2005, Pages 2787-2795

Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYL (O TERT BUTYL)ALANYLLEUCINAL; CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; PROTEASOME; PROTEASOME INHIBITOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 14044278784     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.5.2787     Document Type: Article
Times cited : (42)

References (44)
  • 2
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101:455.
    • (2000) Cell , vol.101 , pp. 455
    • Sakaguchi, S.1
  • 3
    • 0035862336 scopus 로고    scopus 로고
    • Differentiation of T regulatory cells by immature dendritic cells
    • Roncarolo, M. G., M. K. Levings, and C. Traversari. 2001. Differentiation of T regulatory cells by immature dendritic cells. J. Exp. Med. 193:F5.
    • (2001) J. Exp. Med. , vol.193
    • Roncarolo, M.G.1    Levings, M.K.2    Traversari, C.3
  • 4
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389
    • Shevach, E.M.1
  • 5
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • Cong, Y., C. T. Weaver, A. Lazenby, and C. O. Elson. 2002. Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. 169:6112.
    • (2002) J. Immunol. , vol.169 , pp. 6112
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 7
    • 0035316363 scopus 로고    scopus 로고
    • Policing the regulators
    • Sakaguchi, S. 2001. Policing the regulators. Nat. Immunol. 2:283.
    • (2001) Nat. Immunol. , vol.2 , pp. 283
    • Sakaguchi, S.1
  • 8
    • 0035806323 scopus 로고    scopus 로고
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193:1295.
    • (2001) J. Exp. Med. , vol.193 , pp. 1295
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 10
    • 0034679567 scopus 로고    scopus 로고
    • + regulatory cells that control intestinal inflammation
    • + regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295.
    • (2000) J. Exp. Med. , vol.192 , pp. 295
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 14
    • 0346095412 scopus 로고    scopus 로고
    • + regulatory T cells: Thymus or periphery
    • + regulatory T cells: thymus or periphery. J. Clin. Invest. 112:1310.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1310
    • Sakaguchi, S.1
  • 15
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057.
    • (2003) Science , vol.299 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 19
    • 0034743546 scopus 로고    scopus 로고
    • Role of NF-κB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
    • Yoshimura, S., J. Bondeson, F. M. Brennan, B. M. Foxwell, and M. Feldmann. 2001. Role of NF-κB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. Eur. J. Immunol. 31:1883.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1883
    • Yoshimura, S.1    Bondeson, J.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5
  • 20
    • 0035022325 scopus 로고    scopus 로고
    • Effective antigen presentation by dendritic cells is NF-κB dependent: Coordinate regulation of MHC, co-stimulatory molecules and cytokines
    • Yoshimura, S., J. Bondeson, B. M. Foxwell, F. M. Brennan, and M. Feldmann. 2001. Effective antigen presentation by dendritic cells is NF-κB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. Int. Immunol. 13:675.
    • (2001) Int. Immunol. , vol.13 , pp. 675
    • Yoshimura, S.1    Bondeson, J.2    Foxwell, B.M.3    Brennan, F.M.4    Feldmann, M.5
  • 22
    • 0031296660 scopus 로고    scopus 로고
    • The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression
    • Cong, Y., C. T. Weaver, and C. O. Elson. 1997. The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression. J. Immunol. 159:5301.
    • (1997) J. Immunol. , vol.159 , pp. 5301
    • Cong, Y.1    Weaver, C.T.2    Elson, C.O.3
  • 24
    • 0037033434 scopus 로고    scopus 로고
    • T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis
    • Iqbal, N., J. R. Oliver, F. H. Wagner, A. S. Lazenby, C. O. Elson, and C. T. Weaver. 2002. T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J. Exp. Med. 195:71.
    • (2002) J. Exp. Med. , vol.195 , pp. 71
    • Iqbal, N.1    Oliver, J.R.2    Wagner, F.H.3    Lazenby, A.S.4    Elson, C.O.5    Weaver, C.T.6
  • 26
    • 0038617545 scopus 로고    scopus 로고
    • The complex role of interleukin-10 in autoimmunity
    • Groux, H., and F. Cottrez. 2003. The complex role of interleukin-10 in autoimmunity. J. Autoimmun. 20:281.
    • (2003) J. Autoimmun. , vol.20 , pp. 281
    • Groux, H.1    Cottrez, F.2
  • 28
    • 0033104615 scopus 로고    scopus 로고
    • Selective regulation of cytokine induction by adenoviral gene transfer of IκBα into human macrophages: Lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-κB independent
    • Bondeson, J., K. A. Browne, F. M. Brennan, B. M. Foxwell, and M. Feldmann. 1999. Selective regulation of cytokine induction by adenoviral gene transfer of IκBα into human macrophages: lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-κB independent. J. Immunol. 162:2939.
    • (1999) J. Immunol. , vol.162 , pp. 2939
    • Bondeson, J.1    Browne, K.A.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5
  • 29
    • 0029912242 scopus 로고    scopus 로고
    • Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-κB
    • Griscavage, J. M., S. Wilk, and L. J. Ignarro. 1996. Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-κB. Proc. Natl. Acad. Sci. USA 93:3308.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3308
    • Griscavage, J.M.1    Wilk, S.2    Ignarro, L.J.3
  • 32
    • 0036198493 scopus 로고    scopus 로고
    • Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model
    • Zollner, T. M., M. Podda, C. Pien, P. J. Elliott, R. Kaufmann, and W. H. Boehncke. 2002. Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model. J. Clin. Invest. 109:671.
    • (2002) J. Clin. Invest. , vol.109 , pp. 671
    • Zollner, T.M.1    Podda, M.2    Pien, C.3    Elliott, P.J.4    Kaufmann, R.5    Boehncke, W.H.6
  • 35
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou, I., A. Sarukhan, L. Klein, and H. von Boehmer. 2002. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3:756.
    • (2002) Nat. Immunol. , vol.3 , pp. 756
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 36
    • 0033812843 scopus 로고    scopus 로고
    • Dendritic cells and prospects for transplantation tolerance
    • Fairchild, P. J., and H. Waldmann. 2000. Dendritic cells and prospects for transplantation tolerance. Curr. Opin. Immunol. 12:528.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 528
    • Fairchild, P.J.1    Waldmann, H.2
  • 39
    • 0034613767 scopus 로고    scopus 로고
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192:1213.
    • (2000) J. Exp. Med. , vol.192 , pp. 1213
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 40
    • 0034919344 scopus 로고    scopus 로고
    • Dendritic cells as a tool to induce anergic and regulatory T cells
    • Jonuleit, H., E. Schmitt, K. Steinbrink, and A. H. Enk. 2001. Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol. 22:394.
    • (2001) Trends Immunol. , vol.22 , pp. 394
    • Jonuleit, H.1    Schmitt, E.2    Steinbrink, K.3    Enk, A.H.4
  • 41
    • 0036530016 scopus 로고    scopus 로고
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 99:2468.
    • (2002) Blood , vol.99 , pp. 2468
    • Steinbrink, K.1    Graulich, E.2    Kubsch, S.3    Knop, J.4    Enk, A.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.