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Volumn 12, Issue 12, 2006, Pages 1372-1379

Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN;

EID: 33845543666     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1518     Document Type: Article
Times cited : (360)

References (46)
  • 1
    • 0345016451 scopus 로고    scopus 로고
    • + regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals
    • + regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J. Immunol. 171, 5760-5768 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 5760-5768
    • Cavani, A.1
  • 2
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 5
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 6
    • 0033136302 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317-5326 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 5317-5326
    • Itoh, M.1
  • 7
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2
    • Malek, T.R., Yu, A., Vincek, V., Scibelli, P. & Kong, L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17, 167-178 (2002).
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 8
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 Tcells: Expression of IL-2R α chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik, M., de Moraes, M.L., Pontoux, C., Vasseur, F. & Penit, C. Regulatory CD4 Tcells: expression of IL-2R α chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10, 371-378 (1998).
    • (1998) Int. Immunol. , vol.10 , pp. 371-378
    • Papiernik, M.1    De Moraes, M.L.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 9
    • 0033682056 scopus 로고    scopus 로고
    • + immunoregulatory Tcells that control autoimmune diabetes
    • + immunoregulatory Tcells that control autoimmune diabetes. Immunity 12, 431-440 (2000).
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 10
    • 0042512461 scopus 로고    scopus 로고
    • + regulatory T cells by antigen-processing dendritic cells
    • + regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198, 235-247 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 235-247
    • Yamazaki, S.1
  • 11
    • 0034613767 scopus 로고    scopus 로고
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192, 1213-1222 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 12
    • 0035801477 scopus 로고    scopus 로고
    • Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity
    • Mehling, A. et al. Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity. J. Exp. Med. 194, 615-628 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 615-628
    • Mehling, A.1
  • 13
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson, D.M. et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390, 175-179 (1997).
    • (1997) Nature , vol.390 , pp. 175-179
    • Anderson, D.M.1
  • 14
    • 14444272043 scopus 로고    scopus 로고
    • TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
    • Wong, B.R. et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 272, 25190-25194 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 25190-25194
    • Wong, B.R.1
  • 15
    • 0036218666 scopus 로고    scopus 로고
    • RANK-L and RANK: T cells, bone loss, and mammalian evolution
    • Theill, L.E., Boyle, W.J. & Penninger, J.M. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu. Rev. Immunol. 20, 795-823 (2002).
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 795-823
    • Theill, L.E.1    Boyle, W.J.2    Penninger, J.M.3
  • 16
    • 0034730327 scopus 로고    scopus 로고
    • The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
    • Fata, J.E. et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 103, 41-50 (2000).
    • (2000) Cell , vol.103 , pp. 41-50
    • Fata, J.E.1
  • 17
    • 0031936667 scopus 로고    scopus 로고
    • Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity
    • Grabbe, S. & Schwarz, T. Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol. Today 19, 37-44 (1998).
    • (1998) Immunol. Today , vol.19 , pp. 37-44
    • Grabbe, S.1    Schwarz, T.2
  • 18
    • 0035180065 scopus 로고    scopus 로고
    • + regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • + regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182, 18-32 (2001).
    • (2001) Immunol. Rev. , vol.182 , pp. 18-32
    • Sakaguchi, S.1
  • 19
    • 0029835390 scopus 로고    scopus 로고
    • Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
    • Laufer, T.M., DeKoning, J., Markowitz, J.S., Lo, D. & Glimcher, L.H. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383, 81-85 (1996).
    • (1996) Nature , vol.383 , pp. 81-85
    • Laufer, T.M.1    DeKoning, J.2    Markowitz, J.S.3    Lo, D.4    Glimcher, L.H.5
  • 20
    • 0034679567 scopus 로고    scopus 로고
    • + regulatory cells that control intestinal inflammation
    • + regulatory cells that control intestinal inflammation. J. Exp. Med. 192, 295-302 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 21
    • 0036791004 scopus 로고    scopus 로고
    • + as well as CD25- regulatory T cells
    • + as well as CD25- regulatory T cells. Proc. Natl. Acad. Sci. USA 99, 13031-13036 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13031-13036
    • Lehmann, J.1
  • 22
    • 1642347202 scopus 로고    scopus 로고
    • Neuropilin-1: A surface marker of regulatory T cells
    • Bruder, D. et al. Neuropilin-1: a surface marker of regulatory T cells. Eur. J. Immunol. 34, 623-630 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 623-630
    • Bruder, D.1
  • 23
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2, 389-400 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 24
    • 0037111586 scopus 로고    scopus 로고
    • Long-lived immature dendritic cells mediated by TRANCE-RANK interaction
    • Cremer, I. et al. Long-lived immature dendritic cells mediated by TRANCE-RANK interaction. Blood 100, 3646-3655 (2002).
    • (2002) Blood , vol.100 , pp. 3646-3655
    • Cremer, I.1
  • 25
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. & Steinman, R.M. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 27
    • 4544227402 scopus 로고    scopus 로고
    • Enhanced contact hypersensitivity and antiviral immune responses in vivo by keratinocyte-targeted overexpression of IL-15
    • Loser, K. et al. Enhanced contact hypersensitivity and antiviral immune responses in vivo by keratinocyte-targeted overexpression of IL-15. Eur. J. Immunol. 34, 2022-2031 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2022-2031
    • Loser, K.1
  • 28
    • 0038792101 scopus 로고    scopus 로고
    • + regulatory T cells by targeting of antigens to immature dendritic cells
    • + regulatory T cells by targeting of antigens to immature dendritic cells. Blood 101, 4862-4869 (2003).
    • (2003) Blood , vol.101 , pp. 4862-4869
    • Mahnke, K.1    Quian, Y.2    Knop, J.3    Enk, A.H.4
  • 29
    • 17944376135 scopus 로고    scopus 로고
    • Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice
    • Salomon, B. et al. Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice. J. Exp. Med. 194, 677-684 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 677-684
    • Salomon, B.1
  • 30
    • 33645059178 scopus 로고    scopus 로고
    • Influence of anti-tumor necrosis factor therapy (Adalimumab) on regulatory T cells and dendritic cells in rheumatoid arthritis
    • Dombrecht, E.J. et al. Influence of anti-tumor necrosis factor therapy (Adalimumab) on regulatory T cells and dendritic cells in rheumatoid arthritis. Clin. Exp. Rheumatol. 24, 31-37 (2006).
    • (2006) Clin. Exp. Rheumatol. , vol.24 , pp. 31-37
    • Dombrecht, E.J.1
  • 31
    • 0141678964 scopus 로고    scopus 로고
    • Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    • Bynoe, M.S., Evans, J.T., Viret, C. & Janeway, C.A., Jr. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity 19, 317-328 (2003).
    • (2003) Immunity , vol.19 , pp. 317-328
    • Bynoe, M.S.1    Evans, J.T.2    Viret, C.3    Janeway Jr., C.A.4
  • 32
    • 0037136302 scopus 로고    scopus 로고
    • Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin
    • Geissmann, F. et al. Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin. J. Exp. Med. 196, 417-430 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 417-430
    • Geissmann, F.1
  • 33
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • Scheinecker, C., McHugh, R., Shevach, E.M. & Germain, R.N. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196, 1079-1090 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 34
    • 1642454711 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity
    • Schwarz, A. et al. Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity. J. Immunol. 172, 1036-1043 (2004).
    • (2004) J. Immunol. , vol.172 , pp. 1036-1043
    • Schwarz, A.1
  • 35
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong, Y.Y. et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397, 315-323 (1999).
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1
  • 36
    • 10744220366 scopus 로고    scopus 로고
    • Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin
    • Ashcroft, A.J. et al. Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin. Immunity 19, 849-861 (2003).
    • (2003) Immunity , vol.19 , pp. 849-861
    • Ashcroft, A.J.1
  • 37
    • 0036196305 scopus 로고    scopus 로고
    • + Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
    • + Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity 16, 183-191 (2002).
    • (2002) Immunity , vol.16 , pp. 183-191
    • Green, E.A.1    Choi, Y.2    Flavell, R.A.3
  • 38
    • 0026600377 scopus 로고
    • Vitamin D analogues in the treatment of psoriasis
    • Kragballe, K. Vitamin D analogues in the treatment of psoriasis. J. Cell. Biochem. 49, 46-52 (1992).
    • (1992) J. Cell. Biochem. , vol.49 , pp. 46-52
    • Kragballe, K.1
  • 39
    • 0037018104 scopus 로고    scopus 로고
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195, 603-616 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 603-616
    • Barrat, F.J.1
  • 41
    • 0034939253 scopus 로고    scopus 로고
    • Phototesting in lupus erythematosus: A 15-year experience
    • Kuhn, A. et al. Phototesting in lupus erythematosus: a 15-year experience. J. Am. Acad. Dermatol. 45, 86-95 (2001).
    • (2001) J. Am. Acad. Dermatol. , vol.45 , pp. 86-95
    • Kuhn, A.1
  • 42
    • 0000425845 scopus 로고
    • Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
    • Vassar, R., Rosenberg, M., Ross, S., Tyner, A. & Fuchs, E. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 86, 1563-1567 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1563-1567
    • Vassar, R.1    Rosenberg, M.2    Ross, S.3    Tyner, A.4    Fuchs, E.5
  • 43
    • 33745519519 scopus 로고    scopus 로고
    • FK506 controls CD40L-induced systemic autoimmunity in mice
    • Loser, K. et al. FK506 controls CD40L-induced systemic autoimmunity in mice. J. Invest. Dermatol. 126, 1307-1315 (2006).
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 1307-1315
    • Loser, K.1
  • 44
    • 27144472258 scopus 로고    scopus 로고
    • In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity
    • Loser, K. et al. In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity. Gene Ther. 12, 1294-1304 (2005).
    • (2005) Gene Ther. , vol.12 , pp. 1294-1304
    • Loser, K.1
  • 45
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin(IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • + regulatory T cells by interleukin(IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201, 723-735 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 46
    • 0032960197 scopus 로고    scopus 로고
    • Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage
    • Labeur, M.S. et al. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage. J. Immunol. 162, 168-175 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 168-175
    • Labeur, M.S.1


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