Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria

European Journal of Clinical Pharmacology

Volumn 64, Issue 10, 2008, Pages 987-992

  Lee, Sue Jean ^b,g   McGready, Rose ^a,b,g   Fernandez, Christine ^c,d   Stepniewska, Kasia ^b,g   Paw, Moo Koo ^a   Viladpai Nguen, Samuel Jacher ^a   Thwai, Kyaw Lay ^a   Villegas, Leopoldo ^e,f   Singhasivanon, Pratap ^b   Greenwood, Brian M ^f   White, Nicholas J ^b,g   Nosten, François ^a,b,g  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e Centro de Investigación de Campo   (Venezuela)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^g CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Chloroquine; Malaria; Pharmacokinetics; Plasmodium vivax; Pregnancy

Indexed keywords

CHLOROQUINE; DEETHYLCHLOROQUINE;

ADOLESCENT; ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; FEMALE; HUMAN; MALARIA; MAXIMUM PLASMA CONCENTRATION; PLASMODIUM VIVAX; PREGNANCY; PRIORITY JOURNAL; THAILAND; TIME TO MAXIMUM PLASMA CONCENTRATION;

ACUTE DISEASE; ADOLESCENT; ADULT; ANIMALS; ANTIMALARIALS; AREA UNDER CURVE; CHLOROQUINE; FEMALE; HUMANS; MALARIA, VIVAX; PLASMODIUM VIVAX; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; RETROSPECTIVE STUDIES; THAILAND; YOUNG ADULT;

EID: 53249137892     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-008-0500-z     Document Type: Article

References (15)

1. R McGready K Stepniewska N Lindegardh EA Ashley Y La P Singhasivanon NJ White F Nosten 2006 The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria Eur J Clin Pharmacol 62 12 1021 1031
2. SA Ward EJ Sevene IM Hastings F Nosten R McGready 2007 Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance Lancet Infect Dis 7 2 136 144
3. R McGready K Stepniewska MD Edstein T Cho G Gilveray S Looareesuwan NJ White F Nosten 2003 The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria Eur J Clin Pharmacol 59 7 545 552
4. R McGready K Stepniewska E Seaton T Cho D Cho A Ginsberg MD Edstein E Ashley S Looareesuwan NJ White F Nosten 2003 Pregnancy and use of oral contraceptives reduces the biotransformation of proguanil to cycloguanil Eur J Clin Pharmacol 59 7 553 557
5. R McGready K Stepniewska SA Ward T Cho G Gilveray S Looareesuwan NJ White F Nosten 2006 Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria Eur J Clin Pharmacol 62 5 367 371
6. K Na-Bangchang C Manyando R Ruengweerayut D Kioy M Mulenga GB Miller J Konsil 2005 The pharmacokinetics and pharmacodynamics of atovaquone and proguanil for the treatment of uncomplicated falciparum malaria in third-trimester pregnant women Eur J Clin Pharmacol 61 8 573 582
7. F Nosten J Karbwang NJ White Honeymoon K Na Bangchang D Bunnag T Harinasuta 1990 Mefloquine antimalarial prophylaxis in pregnancy: dose finding and pharmacokinetic study Br J Clin Pharmacol 30 1 79 85
8. F Nosten R McGready JA Simpson KL Thwai S Balkan T Cho L Hkirijaroen S Looareesuwan NJ White 1999 Effects of Plasmodium vivax malaria in pregnancy Lancet 354 9178 546 549
9. F Nosten F ter Kuile L Maelankirri B Decludt NJ White 1991 Malaria during pregnancy in an area of unstable endemicity Trans R Soc Trop Med Hyg 85 4 424 429
10. TO Fakeye FA Fehintola OG Ademowo O Walker 2002 Therapeutic monitoring of chloroquine in pregnant women with malaria West Afr J Med 21 4 286 287
11. MC Chukwuani OO Bolaji CO Onyeji ON Makinde FA Ogunbona 2004 Evidence for increased metabolism of chloroquine during the early third trimester of human pregnancy Trop Med Int Health 9 5 601 605
12. R Selvam ST Mathews 1992 Biochemical alterations in Plasmodium vivax-infected malarial patients before and after radical treatment Indian J Malariol 29 2 103 111
13. N Tangpukdee V Thanachartwet S Krudsood N Luplertlop K Pornpininworakij K Chalermrut S Phokham S Kano S Looareesuwan P Wilairatana 2006 Minor liver profile dysfunctions in Plasmodium vivax, P. malaria and P. ovale patients and normalization after treatment Korean J Parasitol 44 4 295 302
14. S Krishna NJ White 1996 Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications Clin Pharmacokinet 30 4 263 299
15. Y Bergqvist B Domeij-Nyberg 1983 Distribution of chloroquine and its metabolite desethyl-chloroquine in human blood cells and its implication for the quantitative determination of these compounds in serum and plasma J Chromatogr 272 1 137 148