메뉴 건너뛰기




Volumn 106, Issue C, 2010, Pages 21-59

Nuclear receptors, inflammation, and neurodegenerative diseases

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ALITRETINOIN; CALCITRIOL; CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GLITAZONE DERIVATIVE; GLUCOCORTICOID RECEPTOR; LIVER X RECEPTOR; NUCLEAR RECEPTOR COACTIVATOR; NUCLEAR RECEPTOR RELATED FACTOR 1; ORPHAN NUCLEAR RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR ALPHA; RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR GAMMA; ROSIGLITAZONE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; CELL RECEPTOR;

EID: 77955911207     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/S0065-2776(10)06002-5     Document Type: Chapter
Times cited : (36)

References (201)
  • 1
    • 0037144591 scopus 로고    scopus 로고
    • Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1
    • Aarnisalo P., Kim C.H., Lee J.W., Perlmann T. Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1. J. Biol. Chem. 2002, 277:35118-35123.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35118-35123
    • Aarnisalo, P.1    Kim, C.H.2    Lee, J.W.3    Perlmann, T.4
  • 2
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott N.J., Ronnback L., Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 2006, 7:41-53.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 3
    • 48749085956 scopus 로고    scopus 로고
    • Control of autoimmune diseases by the vitamin D endocrine system
    • Adorini L., Penna G. Control of autoimmune diseases by the vitamin D endocrine system. Nat. Clin. Pract. Rheumatol. 2008, 4:404-412.
    • (2008) Nat. Clin. Pract. Rheumatol. , vol.4 , pp. 404-412
    • Adorini, L.1    Penna, G.2
  • 6
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • Ajami B., Bennett J.L., Krieger C., Tetzlaff W., Rossi F.M. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat. Neurosci. 2007, 10:1538-1543.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 7
    • 0028540710 scopus 로고
    • Inflammatory response in Alzheimer's disease
    • Akiyama H. Inflammatory response in Alzheimer's disease. Tohoku J. Exp. Med. 1994, 174:295-303.
    • (1994) Tohoku J. Exp. Med. , vol.174 , pp. 295-303
    • Akiyama, H.1
  • 9
    • 73149116008 scopus 로고    scopus 로고
    • T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: Are we listening?
    • Appel S.H., Beers D.R., Henkel J.S. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: Are we listening?. Trends Immunol. 2010, 31:7-17.
    • (2010) Trends Immunol. , vol.31 , pp. 7-17
    • Appel, S.H.1    Beers, D.R.2    Henkel, J.S.3
  • 10
    • 36048998867 scopus 로고    scopus 로고
    • Immunotherapy for Alzheimer's disease: Attacking amyloid-beta from the inside
    • Arbel M., Solomon B. Immunotherapy for Alzheimer's disease: Attacking amyloid-beta from the inside. Trends Immunol. 2007, 28:511-513.
    • (2007) Trends Immunol. , vol.28 , pp. 511-513
    • Arbel, M.1    Solomon, B.2
  • 11
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of I κ B synthesis
    • Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of I κ B synthesis. Science 1995, 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 12
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore C., Lee V.M., Trojanowski J.Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 2007, 8:663-672.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 14
    • 70449529633 scopus 로고    scopus 로고
    • The blood-brain barrier and immune function and dysfunction
    • Banks W.A., Erickson M.A. The blood-brain barrier and immune function and dysfunction. Neurobiol. Dis. 2010, 37:26-32.
    • (2010) Neurobiol. Dis. , vol.37 , pp. 26-32
    • Banks, W.A.1    Erickson, M.A.2
  • 16
    • 0035149373 scopus 로고    scopus 로고
    • Inflammation in the nervous system: The human perspective
    • Bauer J., Rauschka H., Lassmann H. Inflammation in the nervous system: The human perspective. Glia 2001, 36:235-243.
    • (2001) Glia , vol.36 , pp. 235-243
    • Bauer, J.1    Rauschka, H.2    Lassmann, H.3
  • 18
    • 55749110043 scopus 로고    scopus 로고
    • CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
    • Beers D.R., Henkel J.S., Zhao W., Wang J., Appel S.H. CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc. Natl. Acad. Sci. USA 2008, 105:15558-15563.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 15558-15563
    • Beers, D.R.1    Henkel, J.S.2    Zhao, W.3    Wang, J.4    Appel, S.H.5
  • 20
    • 52449089987 scopus 로고    scopus 로고
    • Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses
    • Bertram L., Tanzi R.E. Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses. Nat. Rev. Neurosci. 2008, 9:768-778.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 768-778
    • Bertram, L.1    Tanzi, R.E.2
  • 21
    • 74249097818 scopus 로고    scopus 로고
    • Monoclonal antibodies in MS: Mechanisms of action
    • Bielekova B., Becker B.L. Monoclonal antibodies in MS: Mechanisms of action. Neurology 2010, 74(Suppl. 1):S31-S40.
    • (2010) Neurology , vol.74 , Issue.SUPPL. 1
    • Bielekova, B.1    Becker, B.L.2
  • 22
    • 77949940198 scopus 로고    scopus 로고
    • Intracellular toll-like receptors
    • Blasius A.L., Beutler B. Intracellular toll-like receptors. Immunity 2010, 32:305-315.
    • (2010) Immunity , vol.32 , pp. 305-315
    • Blasius, A.L.1    Beutler, B.2
  • 26
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-γ agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T., Callebert J., Heneka M.T., Landreth G., Launay J.M., Hirsch E.C. Protective action of the peroxisome proliferator-activated receptor-γ agonist pioglitazone in a mouse model of Parkinson's disease. J. Neurochem. 2002, 82:615-624.
    • (2002) J. Neurochem. , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3    Landreth, G.4    Launay, J.M.5    Hirsch, E.C.6
  • 28
    • 39549091493 scopus 로고    scopus 로고
    • Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons
    • Brodbeck J., Balestra M.E., Saunders A.M., Roses A.D., Mahley R.W., Huang Y. Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons. Proc. Natl Acad. Sci. USA 2008, 105:1343-1346.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 1343-1346
    • Brodbeck, J.1    Balestra, M.E.2    Saunders, A.M.3    Roses, A.D.4    Mahley, R.W.5    Huang, Y.6
  • 30
    • 0031455626 scopus 로고    scopus 로고
    • Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
    • Caelles C., Gonzalez-Sancho J.M., Munoz A. Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev. 1997, 11:3351-3364.
    • (1997) Genes Dev. , vol.11 , pp. 3351-3364
    • Caelles, C.1    Gonzalez-Sancho, J.M.2    Munoz, A.3
  • 31
    • 0034123924 scopus 로고    scopus 로고
    • Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment
    • Carrithers M.D., Visintin I., Kang S.J., Janeway C.A. Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment. Brain 2000, 123(Pt. 6):1092-1101.
    • (2000) Brain , vol.123 , Issue.PART. 6 , pp. 1092-1101
    • Carrithers, M.D.1    Visintin, I.2    Kang, S.J.3    Janeway, C.A.4
  • 32
    • 0031881687 scopus 로고    scopus 로고
    • Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
    • Castano A., Herrera A.J., Cano J., Machado A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J. Neurochem. 1998, 70:1584-1592.
    • (1998) J. Neurochem. , vol.70 , pp. 1584-1592
    • Castano, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 33
    • 0038193542 scopus 로고    scopus 로고
    • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
    • Castrillo A., Joseph S.B., Marathe C., Mangelsdorf D.J., Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J. Biol. Chem. 2003, 278:10443-10449.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10443-10449
    • Castrillo, A.1    Joseph, S.B.2    Marathe, C.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 34
    • 0242361567 scopus 로고    scopus 로고
    • Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
    • Castrillo A., Joseph S.B., Vaidya S.A., Haberland M., Fogelman A.M., Cheng G., Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol. Cell 2003, 12:805-816.
    • (2003) Mol. Cell , vol.12 , pp. 805-816
    • Castrillo, A.1    Joseph, S.B.2    Vaidya, S.A.3    Haberland, M.4    Fogelman, A.M.5    Cheng, G.6    Tontonoz, P.7
  • 35
    • 38749105771 scopus 로고    scopus 로고
    • Thiazolidinediones as anti-inflammatory and anti-atherogenic agents
    • Ceriello A. Thiazolidinediones as anti-inflammatory and anti-atherogenic agents. Diabetes Metab. Res. Rev. 2008, 24:14-26.
    • (2008) Diabetes Metab. Res. Rev. , vol.24 , pp. 14-26
    • Ceriello, A.1
  • 36
    • 33846571886 scopus 로고    scopus 로고
    • The origin and cell lineage of microglia: New concepts
    • Chan W.Y., Kohsaka S., Rezaie P. The origin and cell lineage of microglia: New concepts. Brain Res. Rev. 2007, 53:344-354.
    • (2007) Brain Res. Rev. , vol.53 , pp. 344-354
    • Chan, W.Y.1    Kohsaka, S.2    Rezaie, P.3
  • 38
    • 58149235153 scopus 로고    scopus 로고
    • A novel mitogen-activated protein kinase phosphatase-1 and glucocorticoid receptor (GR) interacting protein-1-dependent combinatorial mechanism of gene transrepression by GR
    • Cho I.J., Kim S.G. A novel mitogen-activated protein kinase phosphatase-1 and glucocorticoid receptor (GR) interacting protein-1-dependent combinatorial mechanism of gene transrepression by GR. Mol. Endocrinol. 2009, 23:86-99.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 86-99
    • Cho, I.J.1    Kim, S.G.2
  • 39
    • 59149084957 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists as insulin sensitizers: From the discovery to recent progress
    • Cho N., Momose Y. Peroxisome proliferator-activated receptor gamma agonists as insulin sensitizers: From the discovery to recent progress. Curr. Top. Med. Chem. 2008, 8:1483-1507.
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 1483-1507
    • Cho, N.1    Momose, Y.2
  • 42
    • 34447131528 scopus 로고    scopus 로고
    • PPARγ expression profile and its cytokine driven regulation in atopic dermatitis
    • Dahten A., Mergemeier S., Worm M. PPARγ expression profile and its cytokine driven regulation in atopic dermatitis. Allergy 2007, 62:926-933.
    • (2007) Allergy , vol.62 , pp. 926-933
    • Dahten, A.1    Mergemeier, S.2    Worm, M.3
  • 44
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression
    • De Bosscher K., Vanden Berghe W., Haegeman G. The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression. Endocr. Rev. 2003, 24:488-522.
    • (2003) Endocr. Rev. , vol.24 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 45
    • 66449124004 scopus 로고    scopus 로고
    • Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination
    • Defaux A., Zurich M.G., Braissant O., Honegger P., Monnet-Tschudi F. Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination. J. Neuroinflammation 2009, 6:15.
    • (2009) J. Neuroinflammation , vol.6 , pp. 15
    • Defaux, A.1    Zurich, M.G.2    Braissant, O.3    Honegger, P.4    Monnet-Tschudi, F.5
  • 46
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NF κB and iNOS activation
    • Dehmer T., Heneka M.T., Sastre M., Dichgans J., Schulz J.B. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NF κB and iNOS activation. J. Neurochem. 2004, 88:494-501.
    • (2004) J. Neurochem. , vol.88 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 47
    • 0036499074 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonist 15-deoxy-Delta(12, 14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis
    • Diab A., Deng C., Smith J.D., Hussain R.Z., Phanavanh B., Lovett-Racke A.E., Drew P.D., Racke M.K. Peroxisome proliferator-activated receptor-γ agonist 15-deoxy-Delta(12, 14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 2002, 168:2508-2515.
    • (2002) J. Immunol. , vol.168 , pp. 2508-2515
    • Diab, A.1    Deng, C.2    Smith, J.D.3    Hussain, R.Z.4    Phanavanh, B.5    Lovett-Racke, A.E.6    Drew, P.D.7    Racke, M.K.8
  • 48
    • 1242317642 scopus 로고    scopus 로고
    • Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis
    • Diab A., Hussain R.Z., Lovett-Racke A.E., Chavis J.A., Drew P.D., Racke M.K. Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2004, 148:116-126.
    • (2004) J. Neuroimmunol. , vol.148 , pp. 116-126
    • Diab, A.1    Hussain, R.Z.2    Lovett-Racke, A.E.3    Chavis, J.A.4    Drew, P.D.5    Racke, M.K.6
  • 49
    • 33847161302 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity
    • Dunn S.E., Ousman S.S., Sobel R.A., Zuniga L., Baranzini S.E., Youssef S., Crowell A., Loh J., Oksenberg J., Steinman L. Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J. Exp. Med. 2007, 204:321-330.
    • (2007) J. Exp. Med. , vol.204 , pp. 321-330
    • Dunn, S.E.1    Ousman, S.S.2    Sobel, R.A.3    Zuniga, L.4    Baranzini, S.E.5    Youssef, S.6    Crowell, A.7    Loh, J.8    Oksenberg, J.9    Steinman, L.10
  • 50
    • 23744475685 scopus 로고    scopus 로고
    • The ins and outs of T-lymphocyte trafficking to the CNS: Anatomical sites and molecular mechanisms
    • Engelhardt B., Ransohoff R.M. The ins and outs of T-lymphocyte trafficking to the CNS: Anatomical sites and molecular mechanisms. Trends Immunol. 2005, 26:485-495.
    • (2005) Trends Immunol. , vol.26 , pp. 485-495
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 52
    • 71449103001 scopus 로고    scopus 로고
    • Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases
    • Fernandes de Abreu D.A., Eyles D., Feron F. Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases. Psychoneuroendocrinology 2009, 34(Suppl. 1):S265-S277.
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.SUPPL. 1
    • Fernandes de Abreu, D.A.1    Eyles, D.2    Feron, F.3
  • 53
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., Gavin M.A., Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 2003, 4:330-336.
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 55
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-The plaque and its pathogenesis
    • Frohman E.M., Racke M.K., Raine C.S. Multiple sclerosis-The plaque and its pathogenesis. N. Engl. J. Med. 2006, 354:942-955.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 57
    • 13544270278 scopus 로고    scopus 로고
    • Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain
    • Galea I., Palin K., Newman T.A., Van Rooijen N., Perry V.H., Boche D. Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain. Glia 2005, 49:375-384.
    • (2005) Glia , vol.49 , pp. 375-384
    • Galea, I.1    Palin, K.2    Newman, T.A.3    Van Rooijen, N.4    Perry, V.H.5    Boche, D.6
  • 58
    • 69149089036 scopus 로고    scopus 로고
    • Molecular pathogenesis of Parkinson disease: Insights from genetic studies
    • Gasser T. Molecular pathogenesis of Parkinson disease: Insights from genetic studies. Expert Rev. Mol. Med. 2009, 11:e22.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Gasser, T.1
  • 59
    • 8844285984 scopus 로고    scopus 로고
    • Mouse models of Alzheimer's disease: Insight into treatment
    • German D.C., Eisch A.J. Mouse models of Alzheimer's disease: Insight into treatment. Rev. Neurosci. 2004, 15:353-369.
    • (2004) Rev. Neurosci. , vol.15 , pp. 353-369
    • German, D.C.1    Eisch, A.J.2
  • 61
    • 63049122784 scopus 로고    scopus 로고
    • Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
    • Ghisletti S., Huang W., Jepsen K., Benner C., Hardiman G., Rosenfeld M.G., Glass C.K. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009, 23:681-693.
    • (2009) Genes Dev. , vol.23 , pp. 681-693
    • Ghisletti, S.1    Huang, W.2    Jepsen, K.3    Benner, C.4    Hardiman, G.5    Rosenfeld, M.G.6    Glass, C.K.7
  • 62
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass C.K., Saijo K., Winner B., Marchetto M.C., Gage F.H. Mechanisms underlying inflammation in neurodegeneration. Cell 2010, 140:918-934.
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 63
    • 68049098297 scopus 로고    scopus 로고
    • Estrogen and testosterone therapies in multiple sclerosis
    • Gold S.M., Voskuhl R.R. Estrogen and testosterone therapies in multiple sclerosis. Prog. Brain Res. 2009, 175:239-251.
    • (2009) Prog. Brain Res. , vol.175 , pp. 239-251
    • Gold, S.M.1    Voskuhl, R.R.2
  • 64
    • 38449101546 scopus 로고    scopus 로고
    • Topically applied 1, 25-dihydroxyvitamin D3 enhances the suppressive activity of CD4+CD25+ cells in the draining lymph nodes
    • Gorman S., Kuritzky L.A., Judge M.A., Dixon K.M., McGlade J.P., Mason R.S., Finlay-Jones J.J., Hart P.H. Topically applied 1, 25-dihydroxyvitamin D3 enhances the suppressive activity of CD4+CD25+ cells in the draining lymph nodes. J. Immunol. 2007, 179:6273-6283.
    • (2007) J. Immunol. , vol.179 , pp. 6273-6283
    • Gorman, S.1    Kuritzky, L.A.2    Judge, M.A.3    Dixon, K.M.4    McGlade, J.P.5    Mason, R.S.6    Finlay-Jones, J.J.7    Hart, P.H.8
  • 65
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • Goverman J. Autoimmune T cell responses in the central nervous system. Nat. Rev. Immunol. 2009, 9:393-407.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 393-407
    • Goverman, J.1
  • 68
    • 0036020679 scopus 로고    scopus 로고
    • A 1alpha, 25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice
    • Gregori S., Giarratana N., Smiroldo S., Uskokovic M., Adorini L. A 1alpha, 25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice. Diabetes 2002, 51:1367-1374.
    • (2002) Diabetes , vol.51 , pp. 1367-1374
    • Gregori, S.1    Giarratana, N.2    Smiroldo, S.3    Uskokovic, M.4    Adorini, L.5
  • 70
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • Haass C., Selkoe D.J. Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell Biol. 2007, 8:101-112.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 73
    • 0030986236 scopus 로고    scopus 로고
    • A signature motif in transcriptional co-activators mediates binding to nuclear receptors
    • Heery D.M., Kalkhoven E., Hoare S., Parker M.G. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 1997, 387:733-736.
    • (1997) Nature , vol.387 , pp. 733-736
    • Heery, D.M.1    Kalkhoven, E.2    Hoare, S.3    Parker, M.G.4
  • 77
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: A target for neuroprotection?
    • Hirsch E.C., Hunot S. Neuroinflammation in Parkinson's disease: A target for neuroprotection?. Lancet Neurol. 2009, 8:382-397.
    • (2009) Lancet Neurol. , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 78
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 79
    • 67649668789 scopus 로고    scopus 로고
    • Transcriptional integration of TLR2 and TLR4 signaling at the NCoR depresssion checkpoint
    • Huang W., Ghisletti S., Perissi V., Rosenfeld M.G., Glass C.K. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR depresssion checkpoint. Mol. Cell 2009, 35:48-57.
    • (2009) Mol. Cell , vol.35 , pp. 48-57
    • Huang, W.1    Ghisletti, S.2    Perissi, V.3    Rosenfeld, M.G.4    Glass, C.K.5
  • 80
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., Cua D.J., Littman D.R. The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 82
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A., Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010, 327:291-295.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 83
    • 66849099394 scopus 로고    scopus 로고
    • Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism
    • Jetten A.M. Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism. Nucl. Recept. Signal. 2009, 7:e003.
    • (2009) Nucl. Recept. Signal. , vol.7
    • Jetten, A.M.1
  • 84
    • 0031888958 scopus 로고    scopus 로고
    • PPARγ agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C., Ting A.T., Seed B. PPARγ agonists inhibit production of monocyte inflammatory cytokines. Nature 1998, 391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 86
    • 45849105153 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
    • Jin J.J., Kim H.D., Maxwell J.A., Li L., Fukuchi K. Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease. J. Neuroinflammation 2008, 5:23.
    • (2008) J. Neuroinflammation , vol.5 , pp. 23
    • Jin, J.J.1    Kim, H.D.2    Maxwell, J.A.3    Li, L.4    Fukuchi, K.5
  • 87
    • 67649726059 scopus 로고    scopus 로고
    • Common pathological processes and transcriptional pathways in Alzheimer's disease and type 2 diabetes
    • Jones A., Kulozik P., Ostertag A., Herzig S. Common pathological processes and transcriptional pathways in Alzheimer's disease and type 2 diabetes. J. Alzheimers Dis. 2009, 16:787-808.
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 787-808
    • Jones, A.1    Kulozik, P.2    Ostertag, A.3    Herzig, S.4
  • 91
    • 47849100075 scopus 로고    scopus 로고
    • Alzheimer's disease and peripheral infections: The possible contribution from periodontal infections, model and hypothesis
    • Kamer A.R., Dasanayake A.P., Craig R.G., Glodzik-Sobanska L., Bry M., de Leon M.J. Alzheimer's disease and peripheral infections: The possible contribution from periodontal infections, model and hypothesis. J. Alzheimers Dis. 2008, 13:437-449.
    • (2008) J. Alzheimers Dis. , vol.13 , pp. 437-449
    • Kamer, A.R.1    Dasanayake, A.P.2    Craig, R.G.3    Glodzik-Sobanska, L.4    Bry, M.5    de Leon, M.J.6
  • 92
    • 77949973725 scopus 로고    scopus 로고
    • Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis
    • Kang Z., Altuntas C.Z., Gulen M.F., Liu C., Giltiay N., Qin H., Liu L., Qian W., Ransohoff R.M., Bergmann C., et al. Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis. Immunity 2010, 32:414-425.
    • (2010) Immunity , vol.32 , pp. 414-425
    • Kang, Z.1    Altuntas, C.Z.2    Gulen, M.F.3    Liu, C.4    Giltiay, N.5    Qin, H.6    Liu, L.7    Qian, W.8    Ransohoff, R.M.9    Bergmann, C.10
  • 93
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan M.H., Schindler U., Smiley S.T., Grusby M.J. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996, 4:313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 94
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R., Cox T., Yasayko S.A., Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 2003, 4:337-342.
    • (2003) Nat. Immunol. , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 95
    • 14944367845 scopus 로고    scopus 로고
    • Microglia as a potential bridge between the amyloid beta-peptide and tau
    • Kitazawa M., Yamasaki T.R., LaFerla F.M. Microglia as a potential bridge between the amyloid beta-peptide and tau. Ann. N. Y. Acad. Sci. 2004, 1035:85-103.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1035 , pp. 85-103
    • Kitazawa, M.1    Yamasaki, T.R.2    LaFerla, F.M.3
  • 97
    • 26844468856 scopus 로고    scopus 로고
    • Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor γ levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients
    • Klotz L., Schmidt M., Giese T., Sastre M., Knolle P., Klockgether T., Heneka M.T. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor γ levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. J. Immunol. 2005, 175:4948-4955.
    • (2005) J. Immunol. , vol.175 , pp. 4948-4955
    • Klotz, L.1    Schmidt, M.2    Giese, T.3    Sastre, M.4    Knolle, P.5    Klockgether, T.6    Heneka, M.T.7
  • 98
    • 70350459594 scopus 로고    scopus 로고
    • The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity
    • Klotz L., Burgdorf S., Dani I., Saijo K., Flossdorf J., Hucke S., Alferink J., Novak N., Beyer M., Mayer G., et al. The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J. Exp. Med. 2009, 206:2079-2089.
    • (2009) J. Exp. Med. , vol.206 , pp. 2079-2089
    • Klotz, L.1    Burgdorf, S.2    Dani, I.3    Saijo, K.4    Flossdorf, J.5    Hucke, S.6    Alferink, J.7    Novak, N.8    Beyer, M.9    Mayer, G.10
  • 99
    • 67649700039 scopus 로고    scopus 로고
    • Regulated proteolysis of RAGE and AβPP as possible link between type 2 diabetes mellitus and Alzheimer's disease
    • Kojro E., Postina R. Regulated proteolysis of RAGE and AβPP as possible link between type 2 diabetes mellitus and Alzheimer's disease. J. Alzheimers Dis. 2009, 16:865-878.
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 865-878
    • Kojro, E.1    Postina, R.2
  • 102
    • 0030738318 scopus 로고    scopus 로고
    • The novel estrogen receptor-beta subtype: Potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens
    • Kuiper G.G., Gustafsson J.A. The novel estrogen receptor-beta subtype: Potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens. FEBS Lett. 1997, 410:87-90.
    • (1997) FEBS Lett. , vol.410 , pp. 87-90
    • Kuiper, G.G.1    Gustafsson, J.A.2
  • 103
    • 58049202273 scopus 로고    scopus 로고
    • Inflammasomes: Guardians of cytosolic sanctity
    • Lamkanfi M., Dixit V.M. Inflammasomes: Guardians of cytosolic sanctity. Immunol. Rev. 2009, 227:95-105.
    • (2009) Immunol. Rev. , vol.227 , pp. 95-105
    • Lamkanfi, M.1    Dixit, V.M.2
  • 104
    • 0035096330 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy
    • Lassmann H., Bruck W., Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy. Trends Mol. Med. 2001, 7:115-121.
    • (2001) Trends Mol. Med. , vol.7 , pp. 115-121
    • Lassmann, H.1    Bruck, W.2    Lucchinetti, C.3
  • 105
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson L.J., Perry V.H., Dri P., Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 1990, 39:151-170.
    • (1990) Neuroscience , vol.39 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 108
    • 70349191359 scopus 로고    scopus 로고
    • Differential SUMOylation of LXRα and LXRβ mediates transrepression of STAT1 inflammatory signaling in IFN-γ-stimulated brain astrocytes
    • Lee J.H., Park S.M., Kim O.S., Lee C.S., Woo J.H., Park S.J., Joe E.H., Jou I. Differential SUMOylation of LXRα and LXRβ mediates transrepression of STAT1 inflammatory signaling in IFN-γ-stimulated brain astrocytes. Mol. Cell 2009, 35:806-817.
    • (2009) Mol. Cell , vol.35 , pp. 806-817
    • Lee, J.H.1    Park, S.M.2    Kim, O.S.3    Lee, C.S.4    Woo, J.H.5    Park, S.J.6    Joe, E.H.7    Jou, I.8
  • 109
    • 38749147712 scopus 로고    scopus 로고
    • Expression profiling in APP23 mouse brain: Inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment
    • Lefterov I., Bookout A., Wang Z., Staufenbiel M., Mangelsdorf D., Koldamova R. Expression profiling in APP23 mouse brain: Inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment. Mol. Neurodegener. 2007, 2:20.
    • (2007) Mol. Neurodegener. , vol.2 , pp. 20
    • Lefterov, I.1    Bookout, A.2    Wang, Z.3    Staufenbiel, M.4    Mangelsdorf, D.5    Koldamova, R.6
  • 110
    • 42649140235 scopus 로고    scopus 로고
    • Immunobiology of the TAM receptors
    • Lemke G., Rothlin C.V. Immunobiology of the TAM receptors. Nat. Rev. Immunol. 2008, 8:327-336.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 327-336
    • Lemke, G.1    Rothlin, C.V.2
  • 111
    • 23944444890 scopus 로고    scopus 로고
    • IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
    • Lennon V.A., Kryzer T.J., Pittock S.J., Verkman A.S., Hinson S.R. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J. Exp. Med. 2005, 202:473-477.
    • (2005) J. Exp. Med. , vol.202 , pp. 473-477
    • Lennon, V.A.1    Kryzer, T.J.2    Pittock, S.J.3    Verkman, A.S.4    Hinson, S.R.5
  • 112
    • 38449088277 scopus 로고    scopus 로고
    • Antibody-based approaches in Alzheimer's research: Safety, pharmacokinetics, metabolism, and analytical tools
    • Lichtlen P., Mohajeri M.H. Antibody-based approaches in Alzheimer's research: Safety, pharmacokinetics, metabolism, and analytical tools. J. Neurochem. 2008, 104:859-874.
    • (2008) J. Neurochem. , vol.104 , pp. 859-874
    • Lichtlen, P.1    Mohajeri, M.H.2
  • 114
    • 67649682161 scopus 로고    scopus 로고
    • Adiposity, type 2 diabetes, and Alzheimer's disease
    • Luchsinger J.A., Gustafson D.R. Adiposity, type 2 diabetes, and Alzheimer's disease. J. Alzheimers Dis. 2009, 16:693-704.
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 693-704
    • Luchsinger, J.A.1    Gustafson, D.R.2
  • 115
    • 0035691035 scopus 로고    scopus 로고
    • Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures
    • Lue L.F., Walker D.G., Rogers J. Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures. Neurobiol. Aging 2001, 22:945-956.
    • (2001) Neurobiol. Aging , vol.22 , pp. 945-956
    • Lue, L.F.1    Walker, D.G.2    Rogers, J.3
  • 116
    • 18244381020 scopus 로고    scopus 로고
    • The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression
    • Luecke H.F., Yamamoto K.R. The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression. Genes Dev. 2005, 19:1116-1127.
    • (2005) Genes Dev. , vol.19 , pp. 1116-1127
    • Luecke, H.F.1    Yamamoto, K.R.2
  • 117
    • 0032747825 scopus 로고    scopus 로고
    • Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation
    • Maira M., Martens C., Philips A., Drouin J. Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation. Mol. Cell. Biol. 1999, 19:7549-7557.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7549-7557
    • Maira, M.1    Martens, C.2    Philips, A.3    Drouin, J.4
  • 120
    • 33847339301 scopus 로고    scopus 로고
    • NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies
    • McGeer P.L., McGeer E.G. NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies. Neurobiol. Aging 2007, 28:639-647.
    • (2007) Neurobiol. Aging , vol.28 , pp. 639-647
    • McGeer, P.L.1    McGeer, E.G.2
  • 121
    • 0037154974 scopus 로고    scopus 로고
    • Combinatorial control of gene expression by nuclear receptors and coregulators
    • McKenna N.J., O'Malley B.W. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 2002, 108:465-474.
    • (2002) Cell , vol.108 , pp. 465-474
    • McKenna, N.J.1    O'Malley, B.W.2
  • 122
    • 77950345093 scopus 로고    scopus 로고
    • Inflammation 2010: New adventures of an old flame
    • Medzhitov R. Inflammation 2010: New adventures of an old flame. Cell 2010, 140:771-776.
    • (2010) Cell , vol.140 , pp. 771-776
    • Medzhitov, R.1
  • 124
    • 64149102046 scopus 로고    scopus 로고
    • Recent clinical trials and future therapies
    • Meuth S.G., Kleinschnitz C., Wiendl H. Recent clinical trials and future therapies. J. Neurol. 2008, 255(Suppl. 6):93-96.
    • (2008) J. Neurol. , vol.255 , Issue.SUPPL. 6 , pp. 93-96
    • Meuth, S.G.1    Kleinschnitz, C.2    Wiendl, H.3
  • 125
    • 67649185049 scopus 로고    scopus 로고
    • Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
    • Migliore L., Coppede F. Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases. Mutat. Res. 2009, 667:82-97.
    • (2009) Mutat. Res. , vol.667 , pp. 82-97
    • Migliore, L.1    Coppede, F.2
  • 128
  • 129
    • 70349751944 scopus 로고    scopus 로고
    • Lenalidomide (Revlimid) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis
    • Neymotin A., Petri S., Calingasan N.Y., Wille E., Schafer P., Stewart C., Hensley K., Beal M.F., Kiaei M. Lenalidomide (Revlimid) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis. Exp. Neurol. 2009, 220:191-197.
    • (2009) Exp. Neurol. , vol.220 , pp. 191-197
    • Neymotin, A.1    Petri, S.2    Calingasan, N.Y.3    Wille, E.4    Schafer, P.5    Stewart, C.6    Hensley, K.7    Beal, M.F.8    Kiaei, M.9
  • 130
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A., Kirchhoff F., Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005, 308:1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 132
    • 58049194071 scopus 로고    scopus 로고
    • Emergence of the Th17 pathway and its role in host defense
    • O'Quinn D.B., Palmer M.T., Lee Y.K., Weaver C.T. Emergence of the Th17 pathway and its role in host defense. Adv. Immunol. 2008, 99:115-163.
    • (2008) Adv. Immunol. , vol.99 , pp. 115-163
    • O'Quinn, D.B.1    Palmer, M.T.2    Lee, Y.K.3    Weaver, C.T.4
  • 133
    • 54549096762 scopus 로고    scopus 로고
    • Mechanisms of macrophage activation in obesity-induced insulin resistance
    • Odegaard J.I., Chawla A. Mechanisms of macrophage activation in obesity-induced insulin resistance. Nat. Clin. Pract. Endocrinol. Metab. 2008, 4:619-626.
    • (2008) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 619-626
    • Odegaard, J.I.1    Chawla, A.2
  • 135
    • 10644259532 scopus 로고    scopus 로고
    • Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis
    • Offner H. Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis. J. Neurosci. Res. 2004, 78:603-624.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 603-624
    • Offner, H.1
  • 137
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky J.M., Glass C.K. Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 2010, 72:219-246.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 139
    • 67449123312 scopus 로고    scopus 로고
    • On the mechanism of internalization of α-synuclein into microglia: Roles of ganglioside GM1 and lipid raft
    • Park J.Y., Kim K.S., Lee S.B., Ryu J.S., Chung K.C., Choo Y.K., Jou I., Kim J., Park S.M. On the mechanism of internalization of α-synuclein into microglia: Roles of ganglioside GM1 and lipid raft. J. Neurochem. 2009, 110:400-411.
    • (2009) J. Neurochem. , vol.110 , pp. 400-411
    • Park, J.Y.1    Kim, K.S.2    Lee, S.B.3    Ryu, J.S.4    Chung, K.C.5    Choo, Y.K.6    Jou, I.7    Kim, J.8    Park, S.M.9
  • 141
    • 23844468795 scopus 로고    scopus 로고
    • Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli
    • Pei L., Castrillo A., Chen M., Hoffmann A., Tontonoz P. Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli. J. Biol. Chem. 2005, 280:29256-29262.
    • (2005) J. Biol. Chem. , vol.280 , pp. 29256-29262
    • Pei, L.1    Castrillo, A.2    Chen, M.3    Hoffmann, A.4    Tontonoz, P.5
  • 143
    • 33846585119 scopus 로고    scopus 로고
    • Systemic infections and inflammation affect chronic neurodegeneration
    • Perry V.H., Cunningham C., Holmes C. Systemic infections and inflammation affect chronic neurodegeneration. Nat. Rev. Immunol. 2007, 7:161-167.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 161-167
    • Perry, V.H.1    Cunningham, C.2    Holmes, C.3
  • 145
    • 69249100372 scopus 로고    scopus 로고
    • RAGE: Therapeutic target and biomarker of the inflammatory response-The evidence mounts
    • Ramasamy R., Yan S.F., Schmidt A.M. RAGE: Therapeutic target and biomarker of the inflammatory response-The evidence mounts. J. Leukoc. Biol. 2009, 86:505-512.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 505-512
    • Ramasamy, R.1    Yan, S.F.2    Schmidt, A.M.3
  • 146
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: Unique stimuli, specialized responses
    • Ransohoff R.M., Perry V.H. Microglial physiology: Unique stimuli, specialized responses. Annu. Rev. Immunol. 2009, 27:119-145.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 147
    • 0029643780 scopus 로고
    • Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
    • Renaud J.P., Rochel N., Ruff M., Vivat V., Chambon P., Gronemeyer H., Moras D. Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid. Nature 1995, 378:681-689.
    • (1995) Nature , vol.378 , pp. 681-689
    • Renaud, J.P.1    Rochel, N.2    Ruff, M.3    Vivat, V.4    Chambon, P.5    Gronemeyer, H.6    Moras, D.7
  • 148
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 1998, 391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 149
    • 63049083734 scopus 로고    scopus 로고
    • A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
    • Saijo K., Winner B., Carson C.T., Collier J.G., Boyer L., Rosenfeld M.G., Gage F.H., Glass C.K. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 2009, 137:47-59.
    • (2009) Cell , vol.137 , pp. 47-59
    • Saijo, K.1    Winner, B.2    Carson, C.T.3    Collier, J.G.4    Boyer, L.5    Rosenfeld, M.G.6    Gage, F.H.7    Glass, C.K.8
  • 151
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 153
    • 0035214256 scopus 로고    scopus 로고
    • Neurochemical findings in the MPTP model of Parkinson's disease
    • Schmidt N., Ferger B. Neurochemical findings in the MPTP model of Parkinson's disease. J. Neural Transm. 2001, 108:1263-1282.
    • (2001) J. Neural Transm. , vol.108 , pp. 1263-1282
    • Schmidt, N.1    Ferger, B.2
  • 154
    • 0034463164 scopus 로고    scopus 로고
    • Three amino acids specify coactivator choice by retinoid X receptors
    • Shao G., Heyman R.A., Schulman I.G. Three amino acids specify coactivator choice by retinoid X receptors. Mol. Endocrinol. 2000, 14:1198-1209.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1198-1209
    • Shao, G.1    Heyman, R.A.2    Schulman, I.G.3
  • 155
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau A.K., Barstad D., Loria P.M., Cheng L., Kushner P.J., Agard D.A., Greene G.L. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998, 95:927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 157
    • 0002802349 scopus 로고
    • On the transplantation of the rat sarcoma in adult heterogeneous animals
    • Shirai Y. On the transplantation of the rat sarcoma in adult heterogeneous animals. Japan Med. World 1921, 1:14-15.
    • (1921) Japan Med. World , vol.1 , pp. 14-15
    • Shirai, Y.1
  • 160
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • Sospedra M., Martin R. Immunology of multiple sclerosis. Annu. Rev. Immunol. 2005, 23:683-747.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 162
    • 14844282813 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonists inhibit the activation of microglia and astrocytes: Implications for multiple sclerosis
    • Storer P.D., Xu J., Chavis J., Drew P.D. Peroxisome proliferator-activated receptor-γ agonists inhibit the activation of microglia and astrocytes: Implications for multiple sclerosis. J. Neuroimmunol. 2005, 161:113-122.
    • (2005) J. Neuroimmunol. , vol.161 , pp. 113-122
    • Storer, P.D.1    Xu, J.2    Chavis, J.3    Drew, P.D.4
  • 163
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
    • Straus D.S., Glass C.K. Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms. Trends Immunol. 2007, 28:551-558.
    • (2007) Trends Immunol. , vol.28 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 164
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit W.J. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002, 40:133-139.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 165
    • 0032840131 scopus 로고    scopus 로고
    • Transgenic animals in Alzheimer's disease research
    • Sturchler-Pierrat C., Sommer B. Transgenic animals in Alzheimer's disease research. Rev. Neurosci. 1999, 10:15-24.
    • (1999) Rev. Neurosci. , vol.10 , pp. 15-24
    • Sturchler-Pierrat, C.1    Sommer, B.2
  • 167
  • 169
    • 33750576993 scopus 로고    scopus 로고
    • Role of toll-like receptor signalling in Abeta uptake and clearance
    • Tahara K., Kim H.D., Jin J.J., Maxwell J.A., Li L., Fukuchi K. Role of toll-like receptor signalling in Abeta uptake and clearance. Brain 2006, 129:3006-3019.
    • (2006) Brain , vol.129 , pp. 3006-3019
    • Tahara, K.1    Kim, H.D.2    Jin, J.J.3    Maxwell, J.A.4    Li, L.5    Fukuchi, K.6
  • 172
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 174
    • 0026722679 scopus 로고
    • Interleukin 1 and tumor necrosis factor-alpha stimulate the production of colony-stimulating factor 1 by murine astrocytes
    • Thery C., Stanley E.R., Mallat M. Interleukin 1 and tumor necrosis factor-alpha stimulate the production of colony-stimulating factor 1 by murine astrocytes. J. Neurochem. 1992, 59:1183-1186.
    • (1992) J. Neurochem. , vol.59 , pp. 1183-1186
    • Thery, C.1    Stanley, E.R.2    Mallat, M.3
  • 175
    • 35548975206 scopus 로고    scopus 로고
    • Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)α and ERβ ligand treatment
    • Tiwari-Woodruff S., Morales L.B., Lee R., Voskuhl R.R. Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)α and ERβ ligand treatment. Proc. Natl Acad. Sci. USA 2007, 104:14813-14818.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 14813-14818
    • Tiwari-Woodruff, S.1    Morales, L.B.2    Lee, R.3    Voskuhl, R.R.4
  • 176
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARγ
    • Tontonoz P., Spiegelman B.M. Fat and beyond: The diverse biology of PPARγ. Annu. Rev. Biochem. 2008, 77:289-312.
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 177
  • 178
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • Trapp B.D., Nave K.A. Multiple sclerosis: An immune or neurodegenerative disorder?. Annu. Rev. Neurosci. 2008, 31:247-269.
    • (2008) Annu. Rev. Neurosci. , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.A.2
  • 179
    • 11144221176 scopus 로고    scopus 로고
    • Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis
    • Valledor A.F., Hsu L.C., Ogawa S., Sawka-Verhelle D., Karin M., Glass C.K. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc. Natl Acad. Sci. USA 2004, 101:17813-17818.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 17813-17818
    • Valledor, A.F.1    Hsu, L.C.2    Ogawa, S.3    Sawka-Verhelle, D.4    Karin, M.5    Glass, C.K.6
  • 181
    • 0033647323 scopus 로고    scopus 로고
    • Estrogen blocks inducible nitric oxide synthase accumulation in LPS-activated microglia cells
    • Vegeto E., Pollio G., Ciana P., Maggi A. Estrogen blocks inducible nitric oxide synthase accumulation in LPS-activated microglia cells. Exp. Gerontol. 2000, 35:1309-1316.
    • (2000) Exp. Gerontol. , vol.35 , pp. 1309-1316
    • Vegeto, E.1    Pollio, G.2    Ciana, P.3    Maggi, A.4
  • 184
    • 0034536085 scopus 로고    scopus 로고
    • The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs)
    • Webb P., Anderson C.M., Valentine C., Nguyen P., Marimuthu A., West B.L., Baxter J.D., Kushner P.J. The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs). Mol. Endocrinol. 2000, 14:1976-1985.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1976-1985
    • Webb, P.1    Anderson, C.M.2    Valentine, C.3    Nguyen, P.4    Marimuthu, A.5    West, B.L.6    Baxter, J.D.7    Kushner, P.J.8
  • 185
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson disease
    • Wu D.C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D.K., Ischiropoulos H., Przedborski S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 2002, 22:1763-1771.
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 188
    • 77952571744 scopus 로고    scopus 로고
    • Genetic ablation of steroid receptor coactivator-3 promotes PPAR-β-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis
    • Xiao Y., Xu J., Wang S., Mao C., Jin M., Ning G., Zhang Y. Genetic ablation of steroid receptor coactivator-3 promotes PPAR-β-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis. Glia 2010, 58:932-942.
    • (2010) Glia , vol.58 , pp. 932-942
    • Xiao, Y.1    Xu, J.2    Wang, S.3    Mao, C.4    Jin, M.5    Ning, G.6    Zhang, Y.7
  • 189
    • 25444528680 scopus 로고    scopus 로고
    • Agonists for the peroxisome proliferator-activated receptor-α and the retinoid X receptor inhibit inflammatory responses of microglia
    • Xu J., Storer P.D., Chavis J.A., Racke M.K., Drew P.D. Agonists for the peroxisome proliferator-activated receptor-α and the retinoid X receptor inhibit inflammatory responses of microglia. J. Neurosci. Res. 2005, 81:403-411.
    • (2005) J. Neurosci. Res. , vol.81 , pp. 403-411
    • Xu, J.1    Storer, P.D.2    Chavis, J.A.3    Racke, M.K.4    Drew, P.D.5
  • 190
    • 47349118631 scopus 로고    scopus 로고
    • The PPAR-gamma agonist 15-deoxy-delta-prostaglandin J(2) attenuates microglial production of IL-12 family cytokines: Potential relevance to Alzheimer's disease
    • Xu J., Barger S.W., Drew P.D. The PPAR-gamma agonist 15-deoxy-delta-prostaglandin J(2) attenuates microglial production of IL-12 family cytokines: Potential relevance to Alzheimer's disease. PPAR Res. 2008, 2008:349185.
    • (2008) PPAR Res. , vol.2008 , pp. 349185
    • Xu, J.1    Barger, S.W.2    Drew, P.D.3
  • 194
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • Yednock T.A., Cannon C., Fritz L.C., Sanchez-Madrid F., Steinman L., Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992, 356:63-66.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 197
    • 33846821853 scopus 로고    scopus 로고
    • Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes
    • Zhang-Gandhi C.X., Drew P.D. Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes. J. Neuroimmunol. 2007, 183:50-59.
    • (2007) J. Neuroimmunol. , vol.183 , pp. 50-59
    • Zhang-Gandhi, C.X.1    Drew, P.D.2
  • 198
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W., Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 199
    • 0038326633 scopus 로고    scopus 로고
    • A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease
    • Zheng K., Heydari B., Simon D.K. A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease. Arch. Neurol. 2003, 60:722-725.
    • (2003) Arch. Neurol. , vol.60 , pp. 722-725
    • Zheng, K.1    Heydari, B.2    Simon, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.