Combinatorial control of gene expression by nuclear receptors and coregulators

Cell

Volumn 108, Issue 4, 2002, Pages 465-474

  McKenna, Neil J ^a   O'Malley, Bert W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ENDOCRINOLOGY; GENE EXPRESSION REGULATION; HUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0037154974     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00641-4     Document Type: Review

References (102)

1. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A
2. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
3. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems
4. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing
5. The CBP co-activator is a histone acetyltransferase
6. Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases
7. Cloning and characterization of RAP250, a novel nuclear receptor coactivator
8. Interaction of proteins with transcriptionally active estrogen receptors
9. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
10. Role of CBP/p300 in nuclear receptor signalling
11. A transcriptional co-repressor that interacts with nuclear hormone receptors
12. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
13. Regulation of transcription by a protein methyltransferase
14. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase
15. Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptor-induced gene transcription
16. Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha
17. The steroid and thyroid hormone receptor superfamily
18. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors
19. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
20. AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor
21. Continuous recycling: A mechanism for modulatory signal transduction
22. Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
23. Orphan nuclear receptors: From gene to function
24. Negative effect of the transcriptional activator GAL4
25. Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring?
26. Estrogen receptor-associated proteins: Possible mediators of hormone-induced transcription
27. A signature motif in transcriptional co-activators mediates binding to nuclear receptors
28. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
29. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
30. Primary structure and expression of a functional human glucocorticoid receptor cDNA
31. The SMRT corepressor is regulated by a MEK-1 kinase pathway: Inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export
32. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors
33. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
34. The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
35. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
36. Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM)
37. Basic guides to the mechanism of estrogen action
38. Combinatorial roles of the nuclear receptor corepressor in transcription and development
39. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
40. Estrogen receptors: Selective ligands, partners, and distinctive pharmacology
41. Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
42. Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors
43. Transcription factor-specific requirements for coactivators and their acetyltransferase functions
44. Cloning of a novel receptor expressed in rat prostate and ovary
45. A steroid receptor coactivator, SRA, functions as an RNA transcript and is present in an SRC-1 complex
46. Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
47. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
48. A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo
49. Like attracts like: Getting RNA processing together in the nucleus
50. RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2
51. The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation
52. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP
53. A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
54. The RXR heterodimers and orphan receptors
55. Distinct steady state nuclear hormone receptor coregulator complexes exist in vivo
56. Nuclear receptor coregulators: Cellular and molecular biology
57. The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
58. Ovalbumin messenger RNA of chick oviduct: Partial characterization, estrogen dependence, and translation in vitro
59. Steroid hormone receptors compete for factors that mediate their enhancer function
60. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
61. An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens
62. FHL2, a novel tissue-specific coactivator of the androgen receptor
63. Transcriptional coactivator complexes
64. Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors
65. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
66. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily
67. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
68. Peptide antagonists of the human estrogen receptor
69. Studies on the mechanism of estrogen-mediated tissue differentiation: Regulation of nuclear transcription and induction of new RNA species
70. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
71. Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA
72. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
73. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
74. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
75. Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones
76. Coregulator codes of transcriptional regulation by nuclear receptors
77. Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway
78. Progesterone-binding components of chick oviduct: XIII. Receptor B subunit protein purified to apparent homogeneity from laying hen oviducts
79. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
80. Sharp, an inducible cofactor that integrates nuclear receptor repression and activation
81. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
82. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
83. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen
84. Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites
85. Steroid receptor coactivator-1 is a histone acetyltransferase
86. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent
87. Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator
88. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
89. Molecular mechanisms of action of steroid/thyroid receptor superfamily members
90. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
91. Regulation of somatic growth by the p160 coactivator p/CIP
92. Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor
93. The nuclear-receptor interacting protein (RIP) 140 binds to the human glucocorticoid receptor and modulates hormone-dependent transactivation
94. Characterization of the purified activated glucocorticoid receptor from rat liver cytosol
95. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene
96. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
97. A transcriptional switch mediated by cofactor methylation
98. Steroid receptor regulated transcription of specific genes and gene networks
99. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
100. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
101. Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors
102. Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR