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Volumn 20, Issue 3, 2006, Pages 491-502

Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN DENDRIMER CONJUGATE; MITOGEN ACTIVATED PROTEIN KINASE; POLY(AMIDO)AMINE; PROTEIN SHC; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG;

EID: 33344476520     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2005-0186     Document Type: Article
Times cited : (234)

References (44)
  • 1
    • 0842334814 scopus 로고    scopus 로고
    • Characterization of a membrane-associated estrogen receptor in a rat hypothalamic cell line (D12)
    • Deecher DC, Swiggard P, Frail DE, O'Connor LT 2003 Characterization of a membrane-associated estrogen receptor in a rat hypothalamic cell line (D12). Endocrine 22:211-223
    • (2003) Endocrine , vol.22 , pp. 211-223
    • Deecher, D.C.1    Swiggard, P.2    Frail, D.E.3    O'Connor, L.T.4
  • 3
    • 0344549854 scopus 로고    scopus 로고
    • Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae
    • Kim HP, Lee JY, Jeong JK, Bae SW, Lee HK, Jo I 1999 Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae. Biochem Biophys Res Commun 263:257-262
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 257-262
    • Kim, H.P.1    Lee, J.Y.2    Jeong, J.K.3    Bae, S.W.4    Lee, H.K.5    Jo, I.6
  • 4
    • 0034802322 scopus 로고    scopus 로고
    • Cell localization, physiology, and nongenomic actions of estrogen receptors
    • Levin ER 2001 Cell localization, physiology, and nongenomic actions of estrogen receptors. J Appl Physiol 91:1860-1867
    • (2001) J Appl Physiol , vol.91 , pp. 1860-1867
    • Levin, E.R.1
  • 5
    • 0036224417 scopus 로고    scopus 로고
    • Cellular functions of plasma membrane estrogen receptors
    • Levin ER 2002 Cellular functions of plasma membrane estrogen receptors. Steroids 67:471-475
    • (2002) Steroids , vol.67 , pp. 471-475
    • Levin, E.R.1
  • 6
    • 0037371627 scopus 로고    scopus 로고
    • Identification of a structural determinant necessary for the localization and function of estrogen receptor α at the plasma membrane
    • Razandi M, Alton G, Pedram A, Ghonshani S, Webb P, Levin ER 2003 Identification of a structural determinant necessary for the localization and function of estrogen receptor α at the plasma membrane. Mol Cell Biol 23:1633-1646
    • (2003) Mol Cell Biol , vol.23 , pp. 1633-1646
    • Razandi, M.1    Alton, G.2    Pedram, A.3    Ghonshani, S.4    Webb, P.5    Levin, E.R.6
  • 10
    • 0034644608 scopus 로고    scopus 로고
    • Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells
    • Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR 2000 Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells. Circ Res 87:677-682
    • (2000) Circ Res , vol.87 , pp. 677-682
    • Haynes, M.P.1    Sinha, D.2    Russell, K.S.3    Collinge, M.4    Fulton, D.5    Morales-Ruiz, M.6    Sessa, W.C.7    Bender, J.R.8
  • 11
    • 0037324382 scopus 로고    scopus 로고
    • Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells
    • Simoncini T, Rabkin E, Liao JK 2003 Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol 23:198-203
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 198-203
    • Simoncini, T.1    Rabkin, E.2    Liao, J.K.3
  • 12
    • 0037184912 scopus 로고    scopus 로고
    • Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology
    • Pedram A, Razandi M, Aitkenhead M, Hughes CC, Levin ER 2002 Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology. J Biol Chem 277:50768-50775
    • (2002) J Biol Chem , vol.277 , pp. 50768-50775
    • Pedram, A.1    Razandi, M.2    Aitkenhead, M.3    Hughes, C.C.4    Levin, E.R.5
  • 13
    • 0035834075 scopus 로고    scopus 로고
    • Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line
    • USA
    • Vasudevan N, Kow LM, Pfaff DW 2001 Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line. Proc Natl Acad Sci USA 98:12267-12271
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 12267-12271
    • Vasudevan, N.1    Kow, L.M.2    Pfaff, D.W.3
  • 14
    • 0035347192 scopus 로고    scopus 로고
    • Rapid actions of plasma membrane estrogen receptors
    • Kelly MJ, Levin ER 2001 Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 12:152-156
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 152-156
    • Kelly, M.J.1    Levin, E.R.2
  • 16
    • 0142151032 scopus 로고    scopus 로고
    • Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C
    • Qiu J, Bosch MA, Tobias SC, Grandy DK, Scanlan TS, Ronnekleiv OK, Kelly MJ 2003 Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C. J Neurosci 23:9529-9540
    • (2003) J Neurosci , vol.23 , pp. 9529-9540
    • Qiu, J.1    Bosch, M.A.2    Tobias, S.C.3    Grandy, D.K.4    Scanlan, T.S.5    Ronnekleiv, O.K.6    Kelly, M.J.7
  • 17
    • 0037085714 scopus 로고    scopus 로고
    • 17β-Estradiol inhibits high-voltage-activated calcium channel currents in rat sensory neurons via a nongenomic mechanism
    • Lee DY, Chai YG, Lee EB, Kim KW, Nah SY, Oh TH, Rhim H 2002 17β-Estradiol inhibits high-voltage-activated calcium channel currents in rat sensory neurons via a nongenomic mechanism. Life Sci 70:2047-2059
    • (2002) Life Sci , vol.70 , pp. 2047-2059
    • Lee, D.Y.1    Chai, Y.G.2    Lee, E.B.3    Kim, K.W.4    Nah, S.Y.5    Oh, T.H.6    Rhim, H.7
  • 18
    • 0033621772 scopus 로고    scopus 로고
    • Estradiol-17β-BSA stimulates Ca(2+) uptake through nongenomic pathways in primary rabbit kidney proximal tubule cells: Involvement of cAMP and PKC
    • Han HJ, Lee YH, Park SH 2000 Estradiol-17β-BSA stimulates Ca(2+) uptake through nongenomic pathways in primary rabbit kidney proximal tubule cells: involvement of cAMP and PKC. J Cell Physiol 183:37-44
    • (2000) J Cell Physiol , vol.183 , pp. 37-44
    • Han, H.J.1    Lee, Y.H.2    Park, S.H.3
  • 19
    • 12344289207 scopus 로고    scopus 로고
    • Bovine serum albumin-estrogen compounds differentially alter gonadotropin-releasing hormone-1 neuronal activity
    • Temple JL, Wray S 2005 Bovine serum albumin-estrogen compounds differentially alter gonadotropin-releasing hormone-1 neuronal activity. Endocrinology 146:558-563
    • (2005) Endocrinology , vol.146 , pp. 558-563
    • Temple, J.L.1    Wray, S.2
  • 20
    • 0345257777 scopus 로고    scopus 로고
    • Estradiol modulates acetylcholine-induced Ca2+ signals in LHRH-releasing GT1-7 cells through a membrane binding site
    • Morales A, Diaz M, Ropero AB, Nadal A, Alonso R 2003 Estradiol modulates acetylcholine-induced Ca2+ signals in LHRH-releasing GT1-7 cells through a membrane binding site. Eur J Neurosci 18:2505-2514
    • (2003) Eur J Neurosci , vol.18 , pp. 2505-2514
    • Morales, A.1    Diaz, M.2    Ropero, A.B.3    Nadal, A.4    Alonso, R.5
  • 21
    • 1842638505 scopus 로고    scopus 로고
    • Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways
    • Bulayeva NN, Gametchu B, Watson CS 2004 Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways. Steroids 69:181-192
    • (2004) Steroids , vol.69 , pp. 181-192
    • Bulayeva, N.N.1    Gametchu, B.2    Watson, C.S.3
  • 22
    • 0038579793 scopus 로고    scopus 로고
    • An oestrogen membrane receptor participates in estradiol actions for the prevention of amyloid-β peptide1-40-induced toxicity in septal-derived cholinergic SN56 cells
    • Marin R, Guerra B, Morales A, Diaz M, Alonso R 2003 An oestrogen membrane receptor participates in estradiol actions for the prevention of amyloid-β peptide1-40-induced toxicity in septal-derived cholinergic SN56 cells. J Neurochem 85:1180-1189
    • (2003) J Neurochem , vol.85 , pp. 1180-1189
    • Marin, R.1    Guerra, B.2    Morales, A.3    Diaz, M.4    Alonso, R.5
  • 24
    • 0031059270 scopus 로고    scopus 로고
    • The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site
    • Anstead GM, Carlson KE, Katzenellenbogen JA 1997 The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site. Steroids 62:268-303
    • (1997) Steroids , vol.62 , pp. 268-303
    • Anstead, G.M.1    Carlson, K.E.2    Katzenellenbogen, J.A.3
  • 25
    • 0035342007 scopus 로고    scopus 로고
    • Poly(amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications
    • Esfand R, Tomalia DA 2001 Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov Today 6:427-436
    • (2001) Drug Discov Today , vol.6 , pp. 427-436
    • Esfand, R.1    Tomalia, D.A.2
  • 26
    • 0015902629 scopus 로고
    • Photoaffinity labels for estrogen binding proteins of rat uterus
    • Katzenellenbogen JA, Johnson Jr HJ, Myers HN 1973 Photoaffinity labels for estrogen binding proteins of rat uterus. Biochemistry 12:4085-4092
    • (1973) Biochemistry , vol.12 , pp. 4085-4092
    • Katzenellenbogen, J.A.1    Johnson Jr., H.J.2    Myers, H.N.3
  • 27
    • 0030734795 scopus 로고    scopus 로고
    • Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: Evidence that an open pocket conformation is required for ligand interaction
    • Carlson KE, Choi I, Gee A, Katzenellenbogen BS, Katzenellenbogen JA 1997 Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: evidence that an open pocket conformation is required for ligand interaction. Biochemistry 36:14897-14905
    • (1997) Biochemistry , vol.36 , pp. 14897-14905
    • Carlson, K.E.1    Choi, I.2    Gee, A.3    Katzenellenbogen, B.S.4    Katzenellenbogen, J.A.5
  • 28
    • 0141785350 scopus 로고    scopus 로고
    • Profiling of estrogen up- And down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype
    • Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR, Katzenellenbogen BS 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144:4562-4574
    • (2003) Endocrinology , vol.144 , pp. 4562-4574
    • Frasor, J.1    Danes, J.M.2    Komm, B.3    Chang, K.C.4    Lyttle, C.R.5    Katzenellenbogen, B.S.6
  • 30
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation
    • Song RX, McPherson RA, Adam L, Bao Y, Shupnik M, Kumar R, Santen RJ 2002 Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation. Mol Endocrinol 16:116-127
    • (2002) Mol Endocrinol , vol.16 , pp. 116-127
    • Song, R.X.1    McPherson, R.A.2    Adam, L.3    Bao, Y.4    Shupnik, M.5    Kumar, R.6    Santen, R.J.7
  • 31
    • 1242341918 scopus 로고    scopus 로고
    • The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor α to the plasma membrane
    • USA
    • Song RX, Barnes CJ, Zhang Z, Bao Y, Kumar R, Santen RJ 2004 The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor α to the plasma membrane. Proc Natl Acad Sci USA 101:2076-2081
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 2076-2081
    • Song, R.X.1    Barnes, C.J.2    Zhang, Z.3    Bao, Y.4    Kumar, R.5    Santen, R.J.6
  • 32
    • 8344223854 scopus 로고    scopus 로고
    • Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: Implications for cell proliferation
    • Shupnik MA 2004 Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: implications for cell proliferation. Oncogene 23:7979-7989
    • (2004) Oncogene , vol.23 , pp. 7979-7989
    • Shupnik, M.A.1
  • 33
    • 15744393640 scopus 로고    scopus 로고
    • Regulation of signal transduction pathways by estrogen and progesterone
    • Edwards DP 2005 Regulation of signal transduction pathways by estrogen and progesterone. Annu Rev Physiol 67:337-376
    • (2005) Annu Rev Physiol , vol.67 , pp. 337-376
    • Edwards, D.P.1
  • 34
    • 0034981659 scopus 로고    scopus 로고
    • Specific targeting of folate-dendrimer MRI contrast agents to the high affinity folate receptor expressed in ovarian tumor xenografts
    • Konda SD, Aref M, Wang S, Brechbiel M, Wiener EC 2001 Specific targeting of folate-dendrimer MRI contrast agents to the high affinity folate receptor expressed in ovarian tumor xenografts. Magma 12:104-113
    • (2001) Magma , vol.12 , pp. 104-113
    • Konda, S.D.1    Aref, M.2    Wang, S.3    Brechbiel, M.4    Wiener, E.C.5
  • 35
    • 0344494597 scopus 로고    scopus 로고
    • Polyplexes assembled with internally quaternized PAMAM-OH dendrimer and plasmid DNA have a neutral surface and gene delivery potency
    • Lee JH, Lim YB, Choi JS, Lee Y, Kim TI, Kim HJ, Yoon JK, Kim K, Park JS 2003 Polyplexes assembled with internally quaternized PAMAM-OH dendrimer and plasmid DNA have a neutral surface and gene delivery potency. Bioconjug Chem 14:1214-1221
    • (2003) Bioconjug Chem , vol.14 , pp. 1214-1221
    • Lee, J.H.1    Lim, Y.B.2    Choi, J.S.3    Lee, Y.4    Kim, T.I.5    Kim, H.J.6    Yoon, J.K.7    Kim, K.8    Park, J.S.9
  • 36
    • 0034326297 scopus 로고    scopus 로고
    • Enhanced delivery of antisense oligonucleotides with fluorophore- conjugated PAMAM dendrimers
    • Yoo H, Juliano RL 2000 Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers. Nucleic Acids Res 28:4225-4231
    • (2000) Nucleic Acids Res , vol.28 , pp. 4225-4231
    • Yoo, H.1    Juliano, R.L.2
  • 38
    • 0033200186 scopus 로고    scopus 로고
    • DNA complexing with polyamidoamine dendrimers: Implications for transfection
    • Bielinska AU, Chen C, Johnson J, Baker Jr JR 1999 DNA complexing with polyamidoamine dendrimers: implications for transfection. Bioconjug Chem 10:843-850
    • (1999) Bioconjug Chem , vol.10 , pp. 843-850
    • Bielinska, A.U.1    Chen, C.2    Johnson, J.3    Baker Jr., J.R.4
  • 40
  • 41
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J 2005 Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146:624-632
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 42
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, Weiss H, Schiff R 2004 Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96:926-935
    • (2004) J Natl Cancer Inst , vol.96 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    Ali, S.5    Weiss, H.6    Schiff, R.7
  • 43
    • 3042681155 scopus 로고    scopus 로고
    • Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: Distinct and common target genes for these receptors
    • Stossi F, Barnett DH, Frasor J, Komm B, Lyttle CR, Katzenellenbogen BS 2004 Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: distinct and common target genes for these receptors. Endocrinology 145:3473-3486
    • (2004) Endocrinology , vol.145 , pp. 3473-3486
    • Stossi, F.1    Barnett, D.H.2    Frasor, J.3    Komm, B.4    Lyttle, C.R.5    Katzenellenbogen, B.S.6
  • 44
    • 22344449234 scopus 로고    scopus 로고
    • Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells
    • Rai D, Frolova A, Frasor J, Carpenter AE, Katzenellenbogen BS 2005 Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells. Mol Endocrinol 19:1606-1617
    • (2005) Mol Endocrinol , vol.19 , pp. 1606-1617
    • Rai, D.1    Frolova, A.2    Frasor, J.3    Carpenter, A.E.4    Katzenellenbogen, B.S.5


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