-
1
-
-
36549007517
-
The burden and costs of chronic diseases in low-income and middle-income countries
-
Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M. and Strong, K. (2007) The burden and costs of chronic diseases in low-income and middle-income countries. Lancet 370, 1929-1938
-
(2007)
Lancet
, vol.370
, pp. 1929-1938
-
-
Abegunde, D.O.1
Mathers, C.D.2
Adam, T.3
Ortegon, M.4
Strong, K.5
-
2
-
-
0141611968
-
Management of diabetes mellitus and insulin resistance in patients with cardiovascular disease
-
Fonseca, V. A. (2003) Management of diabetes mellitus and insulin resistance in patients with cardiovascular disease. Am. J. Cardiol. 92, 50J-60J
-
(2003)
Am. J. Cardiol
, vol.92
-
-
Fonseca, V.A.1
-
3
-
-
39049167200
-
Type 2 diabetes and oral antihyperglycemic drugs
-
Mizuno, C. S., Chittiboyina, A. G., Kurtz, T. W., Pershadsingh, H. A. and Avery, M. A. (2008) Type 2 diabetes and oral antihyperglycemic drugs. Curr. Med. Chem. 15, 61-74
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 61-74
-
-
Mizuno, C.S.1
Chittiboyina, A.G.2
Kurtz, T.W.3
Pershadsingh, H.A.4
Avery, M.A.5
-
4
-
-
0034519912
-
Type 2 diabetes and atherosclerosis
-
Donnelly, R. and Davis, K. R. (2000) Type 2 diabetes and atherosclerosis. Diabetes Obes. Metab. 2 (Suppl. 1), S21-S30
-
(2000)
Diabetes Obes. Metab
, vol.2
, Issue.SUPPL. 1
-
-
Donnelly, R.1
Davis, K.R.2
-
5
-
-
45149131667
-
Effects of intensive glucose lowering in type 2 diabetes
-
Gerstein, H. C., Miller, M. E., Byington, R. P. et al. (2008) Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J. Med. 358, 2545-2559
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 2545-2559
-
-
Gerstein, H.C.1
Miller, M.E.2
Byington, R.P.3
-
6
-
-
33745780301
-
Management of hyperglycaemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes
-
Nathan, D. M., Buse, J. B., Davidson, M. B. et al. (2006) Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 49, 1711-1721
-
(2006)
Diabetologia
, vol.49
, pp. 1711-1721
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
-
7
-
-
33745511931
-
Peroxisome proliferator-activated receptors in vascular biology: Molecular mechanisms and clinical implications
-
Touyz, R. M. and Schiffrin, E. L. (2006) Peroxisome proliferator-activated receptors in vascular biology: molecular mechanisms and clinical implications. Vasc. Pharmacol. 45, 19-28
-
(2006)
Vasc. Pharmacol
, vol.45
, pp. 19-28
-
-
Touyz, R.M.1
Schiffrin, E.L.2
-
8
-
-
19244365650
-
Thiazolidinediones
-
Yki-Jarvinen, H. (2004) Thiazolidinediones. N. Engl. J. Med. 351, 1106-1118
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
-
9
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen, S. E. and Wolski, K. (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med. 356, 2457-2471
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
10
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
-
Lincoff, A. M., Wolski, K., Nicholls, S. J. and Nissen, S. E. (2007) Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA, J. Am. Med. Assoc. 298, 1180-1188
-
(2007)
JAMA, J. Am. Med. Assoc
, vol.298
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
11
-
-
0042808525
-
Peroxisome proliferator-activated receptors and the cardiovascular system
-
Chen, Y. E., Fu, M., Zhang, J. et al. (2003) Peroxisome proliferator-activated receptors and the cardiovascular system. Vitam. Horm. 66, 157-188
-
(2003)
Vitam. Horm
, vol.66
, pp. 157-188
-
-
Chen, Y.E.1
Fu, M.2
Zhang, J.3
-
12
-
-
0035146287
-
Control of vascular cell proliferation and migration by PPAR-γ: A new approach to the macrovascular complications of diabetes
-
Hsueh, W. A., Jackson, S. and Law, R. E. (2001) Control of vascular cell proliferation and migration by PPAR-γ: a new approach to the macrovascular complications of diabetes. Diabetes Care 24, 392-397
-
(2001)
Diabetes Care
, vol.24
, pp. 392-397
-
-
Hsueh, W.A.1
Jackson, S.2
Law, R.E.3
-
13
-
-
2442711384
-
Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
-
Marx, N., Duez, H., Fruchart, J. C. and Staels, B. (2004) Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. Circ. Res. 94, 1168-1178
-
(2004)
Circ. Res
, vol.94
, pp. 1168-1178
-
-
Marx, N.1
Duez, H.2
Fruchart, J.C.3
Staels, B.4
-
14
-
-
18844366928
-
Pioglitazone decreases carotid intima-media thickness independently of glycemic control in patients with type 2 diabetes mellitus: Results from a controlled randomized study
-
Langenfeld, M. R., Forst, T., Hohberg, C. et al. (2005) Pioglitazone decreases carotid intima-media thickness independently of glycemic control in patients with type 2 diabetes mellitus: results from a controlled randomized study. Circulation 111, 2525-2531
-
(2005)
Circulation
, vol.111
, pp. 2525-2531
-
-
Langenfeld, M.R.1
Forst, T.2
Hohberg, C.3
-
15
-
-
0034696412
-
Expression and function of PPARγ in rat and human vascular smooth muscle cells
-
Law, R. E., Goetze, S., Xi, X. P. et al. (2000) Expression and function of PPARγ in rat and human vascular smooth muscle cells. Circulation 101, 1311-1318
-
(2000)
Circulation
, vol.101
, pp. 1311-1318
-
-
Law, R.E.1
Goetze, S.2
Xi, X.P.3
-
16
-
-
0032587328
-
PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARγ as a potential mediator in vascular disease
-
Marx, N., Bourcier, T., Sukhova, G. K., Libby, P. and Plutzky, J. (1999) PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARγ as a potential mediator in vascular disease. Arterioscler. Thromb. Vasc. Biol. 19, 546-551
-
(1999)
Arterioscler. Thromb. Vasc. Biol
, vol.19
, pp. 546-551
-
-
Marx, N.1
Bourcier, T.2
Sukhova, G.K.3
Libby, P.4
Plutzky, J.5
-
17
-
-
0344333464
-
Peroxisome proliferator-activated receptor γ activators inhibit gene expression and migration in human vascular smooth muscle cells
-
Marx, N., Schonbeck, U., Lazar, M. A., Libby, P. and Plutzky, J. (1998) Peroxisome proliferator-activated receptor γ activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ. Res. 83, 1097-1103
-
(1998)
Circ. Res
, vol.83
, pp. 1097-1103
-
-
Marx, N.1
Schonbeck, U.2
Lazar, M.A.3
Libby, P.4
Plutzky, J.5
-
18
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J. and Glass, C. K. (1998) The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391, 79-82
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
19
-
-
0141886991
-
Regulation of the growth arrest and DNA damage-inducible gene 45 (GADD45) by peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells
-
Bruemmer, D., Yin, F., Liu, J. et al. (2003) Regulation of the growth arrest and DNA damage-inducible gene 45 (GADD45) by peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells. Circ. Res. 93, e38-e47
-
(2003)
Circ. Res
, vol.93
-
-
Bruemmer, D.1
Yin, F.2
Liu, J.3
-
20
-
-
0035093258
-
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
-
Collins, A. R., Meehan, W. P., Kintscher, U. et al. (2001) Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 21, 365-371
-
(2001)
Arterioscler. Thromb. Vasc. Biol
, vol.21
, pp. 365-371
-
-
Collins, A.R.1
Meehan, W.P.2
Kintscher, U.3
-
21
-
-
0030699447
-
Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterization
-
Igarashi, M., Takeda, Y., Ishibashi, N. et al. (1997) Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterization. Horm. Metab. Res. 29, 444-449
-
(1997)
Horm. Metab. Res
, vol.29
, pp. 444-449
-
-
Igarashi, M.1
Takeda, Y.2
Ishibashi, N.3
-
22
-
-
0032794799
-
Vasculo-protective effects of insulin sensitizing agent pioglitazone in neointimal thickening and hypertensive vascular hypertrophy
-
Yoshimoto, T., Naruse, M., Shizume, H. et al. (1999) Vasculo-protective effects of insulin sensitizing agent pioglitazone in neointimal thickening and hypertensive vascular hypertrophy. Atherosclerosis 145, 333-340
-
(1999)
Atherosclerosis
, vol.145
, pp. 333-340
-
-
Yoshimoto, T.1
Naruse, M.2
Shizume, H.3
-
23
-
-
33846597148
-
Pioglitazone inhibits in-stent restenosis in atherosclerotic rabbits by targeting transforming growth factor-β and MCP-1
-
Joner, M., Farb, A., Cheng, Q. et al. (2007) Pioglitazone inhibits in-stent restenosis in atherosclerotic rabbits by targeting transforming growth factor-β and MCP-1. Arterioscler. Thromb. Vasc. Biol. 27, 182-189
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 182-189
-
-
Joner, M.1
Farb, A.2
Cheng, Q.3
-
24
-
-
0037432590
-
PPARγ-dependent anti-inflammatory action of rosiglitazone in human monocytes: Suppression of TNFα secretion is not mediated by PTEN regulation
-
Hong, G., Davis, B., Khatoon, N., Baker, S. F. and Brown, J. (2003) PPARγ-dependent anti-inflammatory action of rosiglitazone in human monocytes: suppression of TNFα secretion is not mediated by PTEN regulation. Biochem. Biophys. Res. Commun. 303, 782-787
-
(2003)
Biochem. Biophys. Res. Commun
, vol.303
, pp. 782-787
-
-
Hong, G.1
Davis, B.2
Khatoon, N.3
Baker, S.F.4
Brown, J.5
-
25
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C., Ting, A. T. and Seed, B. (1998) PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
26
-
-
0034989969
-
Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-γ in vascular smooth muscle cells
-
Sugawara, A., Takeuchi, K., Uruno, A. et al. (2001) Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-γ in vascular smooth muscle cells. Endocrinology 142, 3125-3134
-
(2001)
Endocrinology
, vol.142
, pp. 3125-3134
-
-
Sugawara, A.1
Takeuchi, K.2
Uruno, A.3
-
27
-
-
0037076294
-
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: Role of peroxisome proliferator-activated receptor-γ
-
Diep, Q. N., El Mabrouk, M., Cohn, J. S. et al. (2002) Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-γ. Circulation 105, 2296-2302
-
(2002)
Circulation
, vol.105
, pp. 2296-2302
-
-
Diep, Q.N.1
El Mabrouk, M.2
Cohn, J.S.3
-
28
-
-
34447309095
-
Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: Restoration by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone
-
Sorrentino, S. A., Bahlmann, F. H., Besler, C. et al. (2007) Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone. Circulation 116, 163-173
-
(2007)
Circulation
, vol.116
, pp. 163-173
-
-
Sorrentino, S.A.1
Bahlmann, F.H.2
Besler, C.3
-
29
-
-
0027983920
-
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
-
Nolan, J. J., Ludvik, B., Beerdsen, P., Joyce, M. and Olefsky, J. (1994) Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N. Engl. J. Med. 331, 1188-1193
-
(1994)
N. Engl. J. Med
, vol.331
, pp. 1188-1193
-
-
Nolan, J.J.1
Ludvik, B.2
Beerdsen, P.3
Joyce, M.4
Olefsky, J.5
-
30
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
-
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M. and Kliewer, S. A. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J. Biol. Chem. 270, 12953-12956
-
(1995)
J. Biol. Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
31
-
-
0033599038
-
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso, I., Gurnell, M., Crowley, V. E. et al. (1999) Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402, 880-883
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
-
32
-
-
4043151601
-
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARγ
-
Tsai, Y. S., Kim, H. J., Takahashi, N. et al. (2004) Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARγ. J. Clin. Invest. 114, 240-249
-
(2004)
J. Clin. Invest
, vol.114
, pp. 240-249
-
-
Tsai, Y.S.1
Kim, H.J.2
Takahashi, N.3
-
33
-
-
1442288375
-
PPARγ agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice
-
Ryan, M. J., Didion, S. P., Mathur, S., Faraci, F. M. and Sigmund, C. D. (2004) PPARγ agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice. Hypertension 43, 661-666
-
(2004)
Hypertension
, vol.43
, pp. 661-666
-
-
Ryan, M.J.1
Didion, S.P.2
Mathur, S.3
Faraci, F.M.4
Sigmund, C.D.5
-
34
-
-
0032993428
-
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats
-
Walker, A. B., Chattington, P. D., Buckingham, R. E. and Williams, G. (1999) The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats. Diabetes 48, 1448-1453
-
(1999)
Diabetes
, vol.48
, pp. 1448-1453
-
-
Walker, A.B.1
Chattington, P.D.2
Buckingham, R.E.3
Williams, G.4
-
35
-
-
4444358440
-
Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats
-
Wu, L., Wang, R., De Champlain, J. and Wilson, T.W. (2004) Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats. Am. J. Hypertens. 17, 749-756
-
(2004)
Am. J. Hypertens
, vol.17
, pp. 749-756
-
-
Wu, L.1
Wang, R.2
De Champlain, J.3
Wilson, T.W.4
-
36
-
-
33847045577
-
Increased insulin-stimulated expression of arterial angiotensinogen and angiotensin type 1 receptor in patients with type 2 diabetes mellitus and atheroma
-
Hodroj, W., Legedz, L., Foudi, N. et al. (2007) Increased insulin-stimulated expression of arterial angiotensinogen and angiotensin type 1 receptor in patients with type 2 diabetes mellitus and atheroma. Arterioscler. Thromb. Vasc. Biol. 27, 525-531
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 525-531
-
-
Hodroj, W.1
Legedz, L.2
Foudi, N.3
-
37
-
-
1442299097
-
Insulin-mediated regulation of the endothelial renin - angiotensin system and vascular cell growth
-
Kamide, K., Rakugi, H., Nagai, M. et al. (2004) Insulin-mediated regulation of the endothelial renin - angiotensin system and vascular cell growth. J. Hypertens. 22, 121-127
-
(2004)
J. Hypertens
, vol.22
, pp. 121-127
-
-
Kamide, K.1
Rakugi, H.2
Nagai, M.3
-
38
-
-
33748131371
-
Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients
-
Savoia, C., Touyz, R. M., Endemann, D. H. et al. (2006) Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients. Hypertension 48, 271-277
-
(2006)
Hypertension
, vol.48
, pp. 271-277
-
-
Savoia, C.1
Touyz, R.M.2
Endemann, D.H.3
-
39
-
-
36348931579
-
Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production
-
Hoo, R. L., Chow, W. S., Yau, M. H. et al. (2007) Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production. Arterioscler. Thromb. Vasc. Biol. 27, 2777-2782
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 2777-2782
-
-
Hoo, R.L.1
Chow, W.S.2
Yau, M.H.3
-
40
-
-
39549118715
-
Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice
-
Ohman, M. K., Shen, Y., Obimba, C. I. et al. (2008) Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 117, 798-805
-
(2008)
Circulation
, vol.117
, pp. 798-805
-
-
Ohman, M.K.1
Shen, Y.2
Obimba, C.I.3
-
41
-
-
34247565554
-
Effects of peroxisome proliferator-activated receptor ligands in modulating tissue factor and tissue factor pathway inhibitor in acutely symptomatic carotid atheromas
-
Golledge, J., Mangan, S. and Clancy, P. (2007) Effects of peroxisome proliferator-activated receptor ligands in modulating tissue factor and tissue factor pathway inhibitor in acutely symptomatic carotid atheromas. Stroke 38, 1501-1508
-
(2007)
Stroke
, vol.38
, pp. 1501-1508
-
-
Golledge, J.1
Mangan, S.2
Clancy, P.3
-
42
-
-
33645323521
-
Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone
-
Luo, Y., Yin, W., Signore, A. P. et al. (2006) Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone. J. Neurochem. 97, 435-448
-
(2006)
J. Neurochem
, vol.97
, pp. 435-448
-
-
Luo, Y.1
Yin, W.2
Signore, A.P.3
-
43
-
-
33947204503
-
Peroxisome proliferator-activated receptor-γ agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents
-
Tureyen, K., Kapadia, R., Bowen, K. K. et al. (2007) Peroxisome proliferator-activated receptor-γ agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J. Neurochem. 101, 41-56
-
(2007)
J. Neurochem
, vol.101
, pp. 41-56
-
-
Tureyen, K.1
Kapadia, R.2
Bowen, K.K.3
-
44
-
-
3242720242
-
Selective disruption of PPARγ 2 impairs the development of adipose tissue and insulin sensitivity
-
Zhang, J., Fu, M., Cui, T. et al. (2004) Selective disruption of PPARγ 2 impairs the development of adipose tissue and insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 101, 10703-10708
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 10703-10708
-
-
Zhang, J.1
Fu, M.2
Cui, T.3
-
45
-
-
0141450254
-
Targeted elimination of peroxisome proliferator-activated receptorγ in β-cells leads to abnormalities in islet mass without compromising glucose homeostasis
-
Rosen, E. D., Kulkarni, R. N., Sarraf, P. et al. (2003) Targeted elimination of peroxisome proliferator-activated receptorγ in β-cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol. Cell. Biol. 23, 7222-7229
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 7222-7229
-
-
Rosen, E.D.1
Kulkarni, R.N.2
Sarraf, P.3
-
46
-
-
34247636362
-
PPARγ 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
-
Medina-Gomez, G., Gray, S. L., Yetukuri, L. et al. (2007) PPARγ 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. PLoS Genet. 3, e64
-
(2007)
PLoS Genet
, vol.3
-
-
Medina-Gomez, G.1
Gray, S.L.2
Yetukuri, L.3
-
47
-
-
9144229185
-
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
-
He, W., Barak, Y., Hevener, A. et al. (2003) Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle. Proc. Natl. Acad. Sci. U.S.A. 100, 15712-15717
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 15712-15717
-
-
He, W.1
Barak, Y.2
Hevener, A.3
-
48
-
-
0346027235
-
Muscle-specific Pparg deletion causes insulin resistance
-
Hevener, A. L., He, W., Barak, Y. et al. (2003) Muscle-specific Pparg deletion causes insulin resistance. Nat. Med. 9, 1491-1497
-
(2003)
Nat. Med
, vol.9
, pp. 1491-1497
-
-
Hevener, A.L.1
He, W.2
Barak, Y.3
-
49
-
-
85047693638
-
Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
-
Norris, A. W., Chen, L., Fisher, S. J. et al. (2003) Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J. Clin. Invest. 112, 608-618
-
(2003)
J. Clin. Invest
, vol.112
, pp. 608-618
-
-
Norris, A.W.1
Chen, L.2
Fisher, S.J.3
-
50
-
-
10644251916
-
Peroxisome proliferator-activated receptor-γ calls for activation in moderation: Lessons from genetics and pharmacology
-
Knouff, C. and Auwerx, J. (2004) Peroxisome proliferator-activated receptor-γ calls for activation in moderation: lessons from genetics and pharmacology. Endocr. Rev. 25, 899-918
-
(2004)
Endocr. Rev
, vol.25
, pp. 899-918
-
-
Knouff, C.1
Auwerx, J.2
-
51
-
-
0037373008
-
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
-
Matsusue, K., Haluzik, M., Lambert, G. et al. (2003) Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J. Clin. Invest. 111, 737-747
-
(2003)
J. Clin. Invest
, vol.111
, pp. 737-747
-
-
Matsusue, K.1
Haluzik, M.2
Lambert, G.3
-
52
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor γ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova, O., Haluzik, M., Matsusue, K. et al. (2003) Liver peroxisome proliferator-activated receptor γ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J. Biol. Chem. 278, 34268-34276
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
-
53
-
-
34948910262
-
Cardiomyocyte expression of PPARγ leads to cardiac dysfunction in mice
-
Son, N. H., Park, T. S., Yamashita, H. et al. (2007) Cardiomyocyte expression of PPARγ leads to cardiac dysfunction in mice. J. Clin. Invest. 117, 2791-2801
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2791-2801
-
-
Son, N.H.1
Park, T.S.2
Yamashita, H.3
-
54
-
-
24044476859
-
Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-γ both induce cardiac hypertrophy in mice
-
Duan, S. Z., Ivashchenko, C. Y., Russell, M. W., Milstone, D. S. and Mortensen, R. M. (2005) Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-γ both induce cardiac hypertrophy in mice. Circ. Res. 97, 372-379
-
(2005)
Circ. Res
, vol.97
, pp. 372-379
-
-
Duan, S.Z.1
Ivashchenko, C.Y.2
Russell, M.W.3
Milstone, D.S.4
Mortensen, R.M.5
-
55
-
-
36649035297
-
Cardiac peroxisome proliferator-activated receptor γ is essential in protecting cardiomyocytes from oxidative damage
-
Ding, G., Fu, M., Qin, Q. et al. (2007) Cardiac peroxisome proliferator-activated receptor γ is essential in protecting cardiomyocytes from oxidative damage. Cardiovasc. Res. 76, 269-279
-
(2007)
Cardiovasc. Res
, vol.76
, pp. 269-279
-
-
Ding, G.1
Fu, M.2
Qin, Q.3
-
56
-
-
52749098189
-
Differential roles of cardiomyocyte and macrophage PPARγ in cardiac fibrosis
-
Caglayan, E., Stauber, B., Collins, A. R. et al. (2008) Differential roles of cardiomyocyte and macrophage PPARγ in cardiac fibrosis. Diabetes 57, 2470-2479
-
(2008)
Diabetes
, vol.57
, pp. 2470-2479
-
-
Caglayan, E.1
Stauber, B.2
Collins, A.R.3
-
57
-
-
36349030319
-
Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-γ agonist treatment occurs independently of changes in myocardial insulin signaling
-
Sena, S., Rasmussen, I. R., Wende, A. R. et al. (2007) Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-γ agonist treatment occurs independently of changes in myocardial insulin signaling. Endocrinology 148, 6047-6053
-
(2007)
Endocrinology
, vol.148
, pp. 6047-6053
-
-
Sena, S.1
Rasmussen, I.R.2
Wende, A.R.3
-
58
-
-
34249907880
-
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
Hevener, A. L., Olefsky, J. M., Reichart, D. et al. (2007) Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J. Clin. Invest. 117, 1658-1669
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
-
59
-
-
23244451031
-
Conditional knockout of macrophage PPARγ increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice
-
Babaev, V. R., Yancey, P. G., Ryzhov, S. V. et al. (2005) Conditional knockout of macrophage PPARγ increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 25, 1647-1653
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.25
, pp. 1647-1653
-
-
Babaev, V.R.1
Yancey, P.G.2
Ryzhov, S.V.3
-
60
-
-
17044430286
-
PPARγ in endothelial cells influences high fat diet-induced hypertension
-
Nicol, C. J., Adachi, M., Akiyama, T. E. and Gonzalez, F. J. (2005) PPARγ in endothelial cells influences high fat diet-induced hypertension. Am. J. Hypertens. 18, 549-556
-
(2005)
Am. J. Hypertens
, vol.18
, pp. 549-556
-
-
Nicol, C.J.1
Adachi, M.2
Akiyama, T.E.3
Gonzalez, F.J.4
-
61
-
-
43049092988
-
An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension
-
Hansmann, G., de Jesus Perez, V. A., Alastalo, T. P. et al. (2008) An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension. J. Clin. Invest. 118, 1846-1857
-
(2008)
J. Clin. Invest
, vol.118
, pp. 1846-1857
-
-
Hansmann, G.1
de Jesus Perez, V.A.2
Alastalo, T.P.3
-
62
-
-
39649100393
-
Interference with PPARγ function in smooth muscle causes vascular dysfunction and hypertension
-
Halabi, C. M., Beyer, A. M., de Lange, W. J. et al. (2008) Interference with PPARγ function in smooth muscle causes vascular dysfunction and hypertension. Cell Metab. 7, 215-226
-
(2008)
Cell Metab
, vol.7
, pp. 215-226
-
-
Halabi, C.M.1
Beyer, A.M.2
de Lange, W.J.3
-
63
-
-
42049101837
-
Interference with PPARγ signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling
-
Beyer, A. M., Baumbach, G. L., Halabi, C. M. et al. (2008) Interference with PPARγ signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension 51, 867-871
-
(2008)
Hypertension
, vol.51
, pp. 867-871
-
-
Beyer, A.M.1
Baumbach, G.L.2
Halabi, C.M.3
-
64
-
-
0344304678
-
Thiazolidinedione use, fluid retention, and congestive heart failure: A consensus statement from the American Heart Association and American Diabetes Association
-
Nesto, R. W., Bell, D., Bonow, R. O. et al. (2003) Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Circulation 108, 2941-2948
-
(2003)
Circulation
, vol.108
, pp. 2941-2948
-
-
Nesto, R.W.1
Bell, D.2
Bonow, R.O.3
-
65
-
-
23844472901
-
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
-
Guan, Y., Hao, C., Cha, D. R. et al. (2005) Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption. Nat. Med. 11, 861-866
-
(2005)
Nat. Med
, vol.11
, pp. 861-866
-
-
Guan, Y.1
Hao, C.2
Cha, D.R.3
-
66
-
-
21544479710
-
Collecting duct-specific deletion of peroxisome proliferator-activated receptor γ blocks thiazolidinedione-induced fluid retention
-
Zhang, H., Zhang, A., Kohan, D. E., Nelson, R. D., Gonzalez, F. J. and Yang, T. (2005) Collecting duct-specific deletion of peroxisome proliferator-activated receptor γ blocks thiazolidinedione-induced fluid retention. Proc. Natl. Acad. Sci. U.S.A. 102, 9406-9411
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 9406-9411
-
-
Zhang, H.1
Zhang, A.2
Kohan, D.E.3
Nelson, R.D.4
Gonzalez, F.J.5
Yang, T.6
-
67
-
-
85076402204
-
PPARγ activation enhances cell surface ENaCα via up-regulation of SGK1 in human collecting duct cells
-
Hong, G., Lockhart, A., Davis, B. et al. (2003) PPARγ activation enhances cell surface ENaCα via up-regulation of SGK1 in human collecting duct cells. FASEB J. 17, 1966-1968
-
(2003)
FASEB J
, vol.17
, pp. 1966-1968
-
-
Hong, G.1
Lockhart, A.2
Davis, B.3
-
68
-
-
33845234619
-
Effect of various diuretic treatments on rosiglitazone-induced fluid retention
-
Karalliedde, J., Buckingham, R., Starkie, M., Lorand, D., Stewart, M. and Viberti, G. (2006) Effect of various diuretic treatments on rosiglitazone-induced fluid retention. J. Am. Soc. Nephrol. 17, 3482-3490
-
(2006)
J. Am. Soc. Nephrol
, vol.17
, pp. 3482-3490
-
-
Karalliedde, J.1
Buckingham, R.2
Starkie, M.3
Lorand, D.4
Stewart, M.5
Viberti, G.6
-
69
-
-
33746690404
-
Plasma concentrations of vascular endothelial growth factor are associated with peripheral oedema in patients treated with thiazolidinedione
-
Emoto, M., Fukuda, N., Nakamori, Y. et al. (2006) Plasma concentrations of vascular endothelial growth factor are associated with peripheral oedema in patients treated with thiazolidinedione. Diabetologia 49, 2217-2218
-
(2006)
Diabetologia
, vol.49
, pp. 2217-2218
-
-
Emoto, M.1
Fukuda, N.2
Nakamori, Y.3
-
70
-
-
33845633231
-
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: Novel mechanism for PPARγ agonist's effects on edema and weight gain
-
Sotiropoulos, K. B., Clermont, A., Yasuda, Y. et al. (2006) Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARγ agonist's effects on edema and weight gain. FASEB J. 20, 1203-1205
-
(2006)
FASEB J
, vol.20
, pp. 1203-1205
-
-
Sotiropoulos, K.B.1
Clermont, A.2
Yasuda, Y.3
-
71
-
-
42949111533
-
Renal cytochrome P450 as a determinant of impaired natriuresis by PPAR-γ ligands in ovariectomized obese rats
-
Yoshioka, K., Wakino, S., Homma, K. et al. (2008) Renal cytochrome P450 as a determinant of impaired natriuresis by PPAR-γ ligands in ovariectomized obese rats. Obesity 16, 965-971
-
(2008)
Obesity
, vol.16
, pp. 965-971
-
-
Yoshioka, K.1
Wakino, S.2
Homma, K.3
-
72
-
-
20044366932
-
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes
-
Pan, H. J., Reifsnyder, P., Vance, D. E., Xiao, Q. and Leiter, E. H. (2005) Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes. Diabetes 54, 1854-1862
-
(2005)
Diabetes
, vol.54
, pp. 1854-1862
-
-
Pan, H.J.1
Reifsnyder, P.2
Vance, D.E.3
Xiao, Q.4
Leiter, E.H.5
-
73
-
-
33745495993
-
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: Relation to dysregulated phosphatidylcholine metabolism
-
Pan, H. J., Lin, Y., Chen, Y. E., Vance, D. E. and Leiter, E. H. (2006) Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. Vasc. Pharmacol. 45, 65-71
-
(2006)
Vasc. Pharmacol
, vol.45
, pp. 65-71
-
-
Pan, H.J.1
Lin, Y.2
Chen, Y.E.3
Vance, D.E.4
Leiter, E.H.5
-
74
-
-
48649095960
-
Rosiglitazone associated fractures in type 2 diabetes: An analysis from A Diabetes Outcome Progression Trial (ADOPT)
-
Kahn, S. E., Zinman, B., Lachin, J. M. et al. (2008) Rosiglitazone associated fractures in type 2 diabetes: an analysis from A Diabetes Outcome Progression Trial (ADOPT). Diabetes Care 31, 845-851
-
(2008)
Diabetes Care
, vol.31
, pp. 845-851
-
-
Kahn, S.E.1
Zinman, B.2
Lachin, J.M.3
-
75
-
-
8844226036
-
-
hyp/hyp mice relocates haematopoiesis to the spleen. EMBO Rep. 5, 1007-1012
-
hyp/hyp mice relocates haematopoiesis to the spleen. EMBO Rep. 5, 1007-1012
-
-
-
-
76
-
-
2142652189
-
PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
-
Akune, T., Ohba, S., Kamekura, S. et al. (2004) PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J. Clin. Invest. 113, 846-855
-
(2004)
J. Clin. Invest
, vol.113
, pp. 846-855
-
-
Akune, T.1
Ohba, S.2
Kamekura, S.3
-
77
-
-
36849034568
-
PPAR-γ regulates osteoclastogenesis in mice
-
Wan, Y., Chong, L. W. and Evans, R. M. (2007) PPAR-γ regulates osteoclastogenesis in mice. Nat. Med. 13, 1496-1503
-
(2007)
Nat. Med
, vol.13
, pp. 1496-1503
-
-
Wan, Y.1
Chong, L.W.2
Evans, R.M.3
-
78
-
-
0034735992
-
Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone
-
Sakamoto, J., Kimura, H., Moriyama, S. et al. (2000) Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone. Biochem. Biophys. Res. Commun. 278, 704-711
-
(2000)
Biochem. Biophys. Res. Commun
, vol.278
, pp. 704-711
-
-
Sakamoto, J.1
Kimura, H.2
Moriyama, S.3
-
79
-
-
33645112691
-
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
-
Peraza, M. A., Burdick, A. D., Marin, H. E., Gonzalez, F. J. and Peters, J. M. (2006) The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol. Sci. 90, 269-295
-
(2006)
Toxicol. Sci
, vol.90
, pp. 269-295
-
-
Peraza, M.A.1
Burdick, A.D.2
Marin, H.E.3
Gonzalez, F.J.4
Peters, J.M.5
-
80
-
-
21544466158
-
A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia
-
Goldberg, R. B., Kendall, D. M., Deeg, M. A. et al. (2005) A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia. Diabetes Care 28, 1547-1554
-
(2005)
Diabetes Care
, vol.28
, pp. 1547-1554
-
-
Goldberg, R.B.1
Kendall, D.M.2
Deeg, M.A.3
-
81
-
-
0034595980
-
Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity
-
Guerre-Millo, M., Gervois, P., Raspe, E. et al. (2000) Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity. J. Biol. Chem. 275, 16638-16642
-
(2000)
J. Biol. Chem
, vol.275
, pp. 16638-16642
-
-
Guerre-Millo, M.1
Gervois, P.2
Raspe, E.3
-
82
-
-
37549041988
-
Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?
-
Barter, P. J. and Rye, K. A. (2008) Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome? Arterioscler. Thromb. Vasc. Biol. 28, 39-46
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 39-46
-
-
Barter, P.J.1
Rye, K.A.2
-
83
-
-
28144451163
-
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus
-
Nissen, S. E., Wolski, K. and Topol, E. J. (2005) Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus. JAMA, J. Am. Med. Assoc. 294, 2581-2586
-
(2005)
JAMA, J. Am. Med. Assoc
, vol.294
, pp. 2581-2586
-
-
Nissen, S.E.1
Wolski, K.2
Topol, E.J.3
-
84
-
-
2442660528
-
Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
-
Tenenbaum, A., Motro, M., Fisman, E. Z. et al. (2004) Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation 109, 2197-2202
-
(2004)
Circulation
, vol.109
, pp. 2197-2202
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
85
-
-
34547661569
-
Safety issues and prospects for future generations of PPAR modulators
-
Rubenstrunk, A., Hanf, R., Hum, D. W., Fruchart, J. C. and Staels, B. (2007) Safety issues and prospects for future generations of PPAR modulators. Biochim. Biophys. Acta 1771, 1065-1081
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1065-1081
-
-
Rubenstrunk, A.1
Hanf, R.2
Hum, D.W.3
Fruchart, J.C.4
Staels, B.5
-
86
-
-
34249087361
-
Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
-
Schug, T. T., Berry, D. C., Shaw, N. S., Travis, S. N. and Noy, N. (2007) Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 129, 723-733
-
(2007)
Cell
, vol.129
, pp. 723-733
-
-
Schug, T.T.1
Berry, D.C.2
Shaw, N.S.3
Travis, S.N.4
Noy, N.5
-
87
-
-
34247546618
-
A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-γ activity
-
Schupp, M., Curtin, J. C., Kim, R. J., Billin, A. N. and Lazar, M. A. (2007) A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-γ activity. Mol. Pharmacol. 71, 1251-1257
-
(2007)
Mol. Pharmacol
, vol.71
, pp. 1251-1257
-
-
Schupp, M.1
Curtin, J.C.2
Kim, R.J.3
Billin, A.N.4
Lazar, M.A.5
-
88
-
-
33750580948
-
Halofenate is a selective peroxisome proliferator-activated receptor γ modulator with antidiabetic activity
-
Allen, T., Zhang, F., Moodie, S. A. et al. (2006) Halofenate is a selective peroxisome proliferator-activated receptor γ modulator with antidiabetic activity. Diabetes 55, 2523-2533
-
(2006)
Diabetes
, vol.55
, pp. 2523-2533
-
-
Allen, T.1
Zhang, F.2
Moodie, S.A.3
-
89
-
-
2642557181
-
A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity
-
Rocchi, S., Picard, F., Vamecq, J. et al. (2001) A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol. Cell 8, 737-747
-
(2001)
Mol. Cell
, vol.8
, pp. 737-747
-
-
Rocchi, S.1
Picard, F.2
Vamecq, J.3
-
90
-
-
12444273748
-
Distinct properties and advantages of a novel peroxisome proliferator-activated protein-γ selective modulator
-
Berger, J. P., Petro, A. E., Macnaul, K. L. et al. (2003) Distinct properties and advantages of a novel peroxisome proliferator-activated protein-γ selective modulator. Mol. Endocrinol. 17, 662-676
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 662-676
-
-
Berger, J.P.1
Petro, A.E.2
Macnaul, K.L.3
-
91
-
-
42749100646
-
Selective modulators of PPAR-γ activity: Molecular aspects related to obesity and side-effects
-
Zhang, F., Lavan, B. E. and Gregoire, F. M. (2007) Selective modulators of PPAR-γ activity: molecular aspects related to obesity and side-effects. PPAR Res. 2007, 32696
-
(2007)
PPAR Res
, vol.2007
, pp. 32696
-
-
Zhang, F.1
Lavan, B.E.2
Gregoire, F.M.3
-
92
-
-
0031013395
-
Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann, J. M., Lenhard, J. M., Oliver, B. B., Ringold, G. M. and Kliewer, S. A. (1997) Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 272, 3406-3410
-
(1997)
J. Biol. Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
93
-
-
10644293716
-
Benzoyl 2-methyl indoles as selective PPARγ modulators
-
Acton, III, J. J., Black, R. M., Jones, A. B. et al. (2005) Benzoyl 2-methyl indoles as selective PPARγ modulators. Bioorg. Med. Chem. Lett. 15, 357-362
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 357-362
-
-
Acton III, J.J.1
Black, R.M.2
Jones, A.B.3
-
94
-
-
25844513595
-
Synthesis and biological activities of novel aryl indole-2-carboxylic acid analogs as PPARγ partial agonists
-
Dropinski, J. F., Akiyama, T., Einstein, M. et al. (2005) Synthesis and biological activities of novel aryl indole-2-carboxylic acid analogs as PPARγ partial agonists. Bioorg. Med. Chem. Lett. 15, 5035-5038
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 5035-5038
-
-
Dropinski, J.F.1
Akiyama, T.2
Einstein, M.3
-
95
-
-
41149097453
-
A novel selective peroxisome proliferator-activator receptor-γ modulator-SPPARγ M5 improves insulin sensitivity with diminished adverse cardiovascular effects
-
Chang, C. H., McNamara, L. A., Wu, M. S. et al. (2008) A novel selective peroxisome proliferator-activator receptor-γ modulator-SPPARγ M5 improves insulin sensitivity with diminished adverse cardiovascular effects. Eur. J. Pharmacol. 584, 192-201
-
(2008)
Eur. J. Pharmacol
, vol.584
, pp. 192-201
-
-
Chang, C.H.1
McNamara, L.A.2
Wu, M.S.3
-
96
-
-
2942724296
-
Pharmacological characteristics of a novel nonthiazolidinedione insulin sensitizer, FK614
-
Minoura, H., Takeshita, S., Ita, M. et al. (2004) Pharmacological characteristics of a novel nonthiazolidinedione insulin sensitizer, FK614. Eur. J. Pharmacol. 494, 273-281
-
(2004)
Eur. J. Pharmacol
, vol.494
, pp. 273-281
-
-
Minoura, H.1
Takeshita, S.2
Ita, M.3
-
97
-
-
0032554866
-
Isoxazolidine-3,5-dione and noncyclic 1,3-dicarbonyl compounds as hypoglycemic agents
-
Shinkai, H., Onogi, S., Tanaka, M. et al. (1998) Isoxazolidine-3,5-dione and noncyclic 1,3-dicarbonyl compounds as hypoglycemic agents. J. Med. Chem. 41, 1927-1933
-
(1998)
J. Med. Chem
, vol.41
, pp. 1927-1933
-
-
Shinkai, H.1
Onogi, S.2
Tanaka, M.3
-
98
-
-
33749426111
-
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARγ agonists
-
Blanc-Delmas, E., Lebegue, N., Wallez, V. et al. (2006) Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARγ agonists. Bioorg. Med. Chem. Lett. 14, 7377-7391
-
(2006)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 7377-7391
-
-
Blanc-Delmas, E.1
Lebegue, N.2
Wallez, V.3
-
99
-
-
0038341857
-
Benzoxazinones as PPARγ agonists. part 1: SAR of three aromatic regions
-
Rybczynski, P. J., Zeck, R. E., Combs, D. W. et al. (2003) Benzoxazinones as PPARγ agonists. part 1: SAR of three aromatic regions. Bioorg. Med. Chem. Lett. 13, 2359-2362
-
(2003)
Bioorg. Med. Chem. Lett
, vol.13
, pp. 2359-2362
-
-
Rybczynski, P.J.1
Zeck, R.E.2
Combs, D.W.3
-
100
-
-
33745850802
-
Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists
-
Chittiboyina, A. G., Venkatraman, M. S., Mizuno, C. S. et al. (2006) Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists. J. Med. Chem. 49, 4072-4084
-
(2006)
J. Med. Chem
, vol.49
, pp. 4072-4084
-
-
Chittiboyina, A.G.1
Venkatraman, M.S.2
Mizuno, C.S.3
-
101
-
-
33645394377
-
A novel partial agonist of peroxisome proliferator-activated receptor-γ (PPARγ) recruits PPARγ-coactivator-1α, prevents triglyceride accumulation, and potentiates insulin signaling in vitro
-
Burgermeister, E., Schnoebelen, A., Flament, A. et al. (2006) A novel partial agonist of peroxisome proliferator-activated receptor-γ (PPARγ) recruits PPARγ-coactivator-1α, prevents triglyceride accumulation, and potentiates insulin signaling in vitro. Mol. Endocrinol. 20, 809-830
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 809-830
-
-
Burgermeister, E.1
Schnoebelen, A.2
Flament, A.3
-
102
-
-
0033973843
-
Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency
-
Miles, P. D., Barak, Y., He, W., Evans, R. M. and Olefsky, J. M. (2000) Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency. J. Clin. Invest. 105, 287-292
-
(2000)
J. Clin. Invest
, vol.105
, pp. 287-292
-
-
Miles, P.D.1
Barak, Y.2
He, W.3
Evans, R.M.4
Olefsky, J.M.5
-
103
-
-
0036843143
-
A new selective peroxisome proliferator-activated receptor γ antagonist with antiobesity and antidiabetic activity
-
Rieusset, J., Touri, F., Michalik, L. et al. (2002) A new selective peroxisome proliferator-activated receptor γ antagonist with antiobesity and antidiabetic activity. Mol. Endocrinol. 16, 2628-2644
-
(2002)
Mol. Endocrinol
, vol.16
, pp. 2628-2644
-
-
Rieusset, J.1
Touri, F.2
Michalik, L.3
-
104
-
-
44049104049
-
T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor-γ binding properties
-
Li, Y., Wang, Z., Furukawa, N. et al. (2008) T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor-γ binding properties. J. Biol. Chem. 283, 9168-9176
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9168-9176
-
-
Li, Y.1
Wang, Z.2
Furukawa, N.3
-
105
-
-
33745437191
-
Angiotensin II induces vascular dysfunction without exacerbating blood pressure elevation in a mouse model of menopause-associated hypertension
-
Javeshghani, D., Sairam, M. R., Neves, M. F., Schiffrin, E. L. and Touyz, R. M. (2006) Angiotensin II induces vascular dysfunction without exacerbating blood pressure elevation in a mouse model of menopause-associated hypertension. J. Hypertens. 24, 1365-1373
-
(2006)
J. Hypertens
, vol.24
, pp. 1365-1373
-
-
Javeshghani, D.1
Sairam, M.R.2
Neves, M.F.3
Schiffrin, E.L.4
Touyz, R.M.5
-
106
-
-
0036670364
-
-
1-receptor blockade in the prevention and reversal of atherosclerosis. J. Hum. Hypertens. 16 (Suppl. 3), S34-S41
-
1-receptor blockade in the prevention and reversal of atherosclerosis. J. Hum. Hypertens. 16 (Suppl. 3), S34-S41
-
-
-
-
107
-
-
2442451618
-
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-γ activity
-
Schupp, M., Janke, J., Clasen, R., Unger, T. and Kintscher, U. (2004) Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-γ activity. Circulation 109, 2054-2057
-
(2004)
Circulation
, vol.109
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
Unger, T.4
Kintscher, U.5
-
108
-
-
33644672013
-
Molecular characterization of new selective peroxisome proliferator-activated receptor γ modulators with angiotensin receptor blocking activity
-
Schupp, M., Clemenz, M., Gineste, R. et al. (2005) Molecular characterization of new selective peroxisome proliferator-activated receptor γ modulators with angiotensin receptor blocking activity. Diabetes 54, 3442-3452
-
(2005)
Diabetes
, vol.54
, pp. 3442-3452
-
-
Schupp, M.1
Clemenz, M.2
Gineste, R.3
-
109
-
-
33750913676
-
Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-γ activation
-
Yoshida, T., Yamagishi, S., Nakamura, K. et al. (2006) Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-γ activation. Diabetologia 49, 3094-3099
-
(2006)
Diabetologia
, vol.49
, pp. 3094-3099
-
-
Yoshida, T.1
Yamagishi, S.2
Nakamura, K.3
-
110
-
-
39749201501
-
Effect of telmisartan on nitric oxide - asymmetrical dimethylarginine system: Role of angiotensin II type 1 receptor γ and peroxisome proliferator activated receptor γ signaling during endothelial aging
-
Scalera, F., Martens-Lobenhoffer, J., Bukowska, A., Lendeckel, U., Tager, M. and Bode-Boger, S. M. (2008) Effect of telmisartan on nitric oxide - asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor γ and peroxisome proliferator activated receptor γ signaling during endothelial aging. Hypertension 51, 696-703
-
(2008)
Hypertension
, vol.51
, pp. 696-703
-
-
Scalera, F.1
Martens-Lobenhoffer, J.2
Bukowska, A.3
Lendeckel, U.4
Tager, M.5
Bode-Boger, S.M.6
-
111
-
-
21744452983
-
PPARγ-activating angiotensin type-1 receptor blockers induce adiponectin
-
Clasen, R., Schupp, M., Foryst-Ludwig, A. et al. (2005) PPARγ-activating angiotensin type-1 receptor blockers induce adiponectin. Hypertension 46, 137-143
-
(2005)
Hypertension
, vol.46
, pp. 137-143
-
-
Clasen, R.1
Schupp, M.2
Foryst-Ludwig, A.3
-
112
-
-
0035844217
-
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists
-
Davies, S. S., Pontsler, A. V., Marathe, G. K. et al. (2001) Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. J. Biol. Chem. 276, 16015-16023
-
(2001)
J. Biol. Chem
, vol.276
, pp. 16015-16023
-
-
Davies, S.S.1
Pontsler, A.V.2
Marathe, G.K.3
-
115
-
-
4143099405
-
Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes
-
Tzameli, I., Fang, H., Ollero, M. et al. (2004) Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes. J. Biol. Chem. 279, 36093-36102
-
(2004)
J. Biol. Chem
, vol.279
, pp. 36093-36102
-
-
Tzameli, I.1
Fang, H.2
Ollero, M.3
-
116
-
-
34249723258
-
Statins activate peroxisome proliferator-activated receptor γ through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages
-
Yano, M., Matsumura, T., Senokuchi, T. et al. (2007) Statins activate peroxisome proliferator-activated receptor γ through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages. Circ. Res. 100, 1442-1451
-
(2007)
Circ. Res
, vol.100
, pp. 1442-1451
-
-
Yano, M.1
Matsumura, T.2
Senokuchi, T.3
-
117
-
-
33845440071
-
2 synthesized by adipocytes during maturation phase contributes to upregulation of fat storage
-
2 synthesized by adipocytes during maturation phase contributes to upregulation of fat storage. FEBS Lett. 580, 6885-6890
-
(2006)
FEBS Lett
, vol.580
, pp. 6885-6890
-
-
Mazid, M.A.1
Chowdhury, A.A.2
Nagao, K.3
-
118
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
-
Huang, J. T., Welch, J. S., Ricote, M. et al. (1999) Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase. Nature 400, 378-382
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
-
119
-
-
4844231742
-
Laminar flow activates peroxisome proliferator-activated receptor-γ in vascular endothelial cells
-
Liu, Y., Zhu, Y., Rannou, F. et al. (2004) Laminar flow activates peroxisome proliferator-activated receptor-γ in vascular endothelial cells. Circulation 110, 1128-1133
-
(2004)
Circulation
, vol.110
, pp. 1128-1133
-
-
Liu, Y.1
Zhu, Y.2
Rannou, F.3
-
120
-
-
28044434102
-
The antiinflammatory effect of laminar flow: The role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase
-
Liu, Y., Zhang, Y., Schmelzer, K. et al. (2005) The antiinflammatory effect of laminar flow: the role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proc. Natl. Acad. Sci. U.S.A. 102, 16747-16752
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 16747-16752
-
-
Liu, Y.1
Zhang, Y.2
Schmelzer, K.3
-
121
-
-
0034640235
-
2 synthase expression in vascular endothelial cells
-
2 synthase expression in vascular endothelial cells. Circ. Res. 86, 967-973
-
(2000)
Circ. Res
, vol.86
, pp. 967-973
-
-
Taba, Y.1
Sasaguri, T.2
Miyagi, M.3
-
122
-
-
41449112452
-
Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor γ expression and adipogenesis in cultured 3T3-L1 cells
-
Christianson, J. L., Nicoloro, S., Straubhaar, J. and Czech, M. P. (2008) Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor γ expression and adipogenesis in cultured 3T3-L1 cells. J. Biol. Chem. 283, 2906-2916
-
(2008)
J. Biol. Chem
, vol.283
, pp. 2906-2916
-
-
Christianson, J.L.1
Nicoloro, S.2
Straubhaar, J.3
Czech, M.P.4
-
123
-
-
34247626853
-
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression
-
Waki, H., Park, K. W., Mitro, N. et al. (2007) The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression. Cell Metab. 5, 357-370
-
(2007)
Cell Metab
, vol.5
, pp. 357-370
-
-
Waki, H.1
Park, K.W.2
Mitro, N.3
-
124
-
-
0033105510
-
Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
-
Xu, H. E., Lambert, M. H., Montana, V. G. et al. (1999) Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol. Cell 3, 397-403
-
(1999)
Mol. Cell
, vol.3
, pp. 397-403
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
-
125
-
-
14044275170
-
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
-
Schopfer, F. J., Lin, Y., Baker, P. R. et al. (2005) Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor γ ligand. Proc. Natl. Acad. Sci. U.S.A. 102, 2340-2345
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 2340-2345
-
-
Schopfer, F.J.1
Lin, Y.2
Baker, P.R.3
-
126
-
-
0036801357
-
Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases
-
Baldus, S., Eiserich, J. P., Brennan, M. L., Jackson, R. M., Alexander, C. B. and Freeman, B. A. (2002) Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radical Biol. Med. 33, 1010
-
(2002)
Free Radical Biol. Med
, vol.33
, pp. 1010
-
-
Baldus, S.1
Eiserich, J.P.2
Brennan, M.L.3
Jackson, R.M.4
Alexander, C.B.5
Freeman, B.A.6
-
127
-
-
0038731081
-
Biological selectivity and functional aspects of protein tyrosine nitration
-
Ischiropoulos, H. (2003) Biological selectivity and functional aspects of protein tyrosine nitration. Biochem. Biophys. Res. Commun. 305, 776-783
-
(2003)
Biochem. Biophys. Res. Commun
, vol.305
, pp. 776-783
-
-
Ischiropoulos, H.1
-
128
-
-
49349115115
-
Protein and lipid nitration: Role in redox signaling and injury
-
Rubbo, H. and Radi, R. (2008) Protein and lipid nitration: role in redox signaling and injury. Biochim. Biophys. Acta 1780, 1318-1324
-
(2008)
Biochim. Biophys. Acta
, vol.1780
, pp. 1318-1324
-
-
Rubbo, H.1
Radi, R.2
-
129
-
-
1642570319
-
Nitric oxide, oxidants, and protein tyrosine nitration
-
Radi, R. (2004) Nitric oxide, oxidants, and protein tyrosine nitration. Proc. Natl. Acad. Sci. U.S.A. 101, 4003-4008
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 4003-4008
-
-
Radi, R.1
-
130
-
-
0037414194
-
Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy
-
Shishehbor, M. H., Aviles, R. J., Brennan, M. L. et al. (2003) Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA, J. Am. Med. Assoc. 289, 1675-1680
-
(2003)
JAMA, J. Am. Med. Assoc
, vol.289
, pp. 1675-1680
-
-
Shishehbor, M.H.1
Aviles, R.J.2
Brennan, M.L.3
-
131
-
-
29644433449
-
Fatty acid transduction of nitric oxide signaling: Multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands
-
Baker, P. R., Lin, Y., Schopfer, F. J. et al. (2005) Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands. J. Biol. Chem. 280, 42464-42475
-
(2005)
J. Biol. Chem
, vol.280
, pp. 42464-42475
-
-
Baker, P.R.1
Lin, Y.2
Schopfer, F.J.3
-
132
-
-
4143113591
-
Red cell membrane and plasma linoleic acid nitration products: Synthesis, clinical identification, and quantitation
-
Baker, P. R., Schopfer, F. J., Sweeney, S. and Freeman, B. A. (2004) Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation. Proc. Natl. Acad. Sci. U.S.A. 101, 11577-11582
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 11577-11582
-
-
Baker, P.R.1
Schopfer, F.J.2
Sweeney, S.3
Freeman, B.A.4
-
133
-
-
34248219070
-
9- and 10-Nitro-oleic acid do not interfere with the GC-MS quantitative determination of nitrite and nitrate in biological fluids when measured as their pentafluorobenzyl derivatives
-
Mitschke, A., Gutzki, F. M. and Tsikas, D. (2007) 9- and 10-Nitro-oleic acid do not interfere with the GC-MS quantitative determination of nitrite and nitrate in biological fluids when measured as their pentafluorobenzyl derivatives. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 287-291
-
(2007)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci
, vol.851
, pp. 287-291
-
-
Mitschke, A.1
Gutzki, F.M.2
Tsikas, D.3
-
134
-
-
0037183523
-
Characterization of linoleic acid nitration in human blood plasma by mass spectrometry
-
Lima, E. S., Di Mascio, P., Rubbo, H. and Abdalla, D. S. (2002) Characterization of linoleic acid nitration in human blood plasma by mass spectrometry. Biochemistry 41, 10717-10722
-
(2002)
Biochemistry
, vol.41
, pp. 10717-10722
-
-
Lima, E.S.1
Di Mascio, P.2
Rubbo, H.3
Abdalla, D.S.4
-
135
-
-
2942595951
-
Biological nitration of arachidonic acid
-
Balazy, M. and Poff, C. D. (2004) Biological nitration of arachidonic acid. Curr. Vasc. Pharmacol. 2, 81-93
-
(2004)
Curr. Vasc. Pharmacol
, vol.2
, pp. 81-93
-
-
Balazy, M.1
Poff, C.D.2
-
136
-
-
0141794273
-
Cholesteryl nitrolinoleate, a nitrated lipid present in human blood plasma and lipoproteins
-
Lima, E. S., Di Mascio, P. and Abdalla, D. S. (2003) Cholesteryl nitrolinoleate, a nitrated lipid present in human blood plasma and lipoproteins. J. Lipid Res. 44, 1660-1666
-
(2003)
J. Lipid Res
, vol.44
, pp. 1660-1666
-
-
Lima, E.S.1
Di Mascio, P.2
Abdalla, D.S.3
-
137
-
-
47049101575
-
Nitro-fatty acid formation and signaling
-
Freeman, B. A., Baker, P. R., Schopfer, F. J., Woodcock, S. R., Napolitano, A. and d'Ischia, M. (2008) Nitro-fatty acid formation and signaling. J. Biol. Chem. 283, 15515-15519
-
(2008)
J. Biol. Chem
, vol.283
, pp. 15515-15519
-
-
Freeman, B.A.1
Baker, P.R.2
Schopfer, F.J.3
Woodcock, S.R.4
Napolitano, A.5
d'Ischia, M.6
-
138
-
-
33746882132
-
Modulation of nitrated lipid signaling by multidrug resistance protein 1 (MRP1): Glutathione conjugation and MRP1-mediated efflux inhibit nitrolinoleic acid-induced, PPARγ-dependent transcription activation
-
Alexander, R. L., Bates, D. J., Wright, M. W., King, S. B. and Morrow, C. S. (2006) Modulation of nitrated lipid signaling by multidrug resistance protein 1 (MRP1): glutathione conjugation and MRP1-mediated efflux inhibit nitrolinoleic acid-induced, PPARγ-dependent transcription activation. Biochemistry 45, 7889-7896
-
(2006)
Biochemistry
, vol.45
, pp. 7889-7896
-
-
Alexander, R.L.1
Bates, D.J.2
Wright, M.W.3
King, S.B.4
Morrow, C.S.5
|