JNK1 and IKKβ: Molecular links between obesity and metabolic dysfunction

FASEB Journal

Volumn 24, Issue 8, 2010, Pages 2596-2611

  Solinas, Giovanni ^a   Karin, Michael ^b  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b San Diego   (United States)

Author keywords

Glucotoxicity; Lipotoxicity; Metabolic inflammation; Metabolic stress; Type 2 diabetes

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AMYLIN; ANTIDIABETIC AGENT; FAS LIGAND; FATTY ACID; HEXOSAMINE; I KAPPA B KINASE BETA; INSULIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SALICYLIC ACID; SALSALATE; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; I KAPPA B KINASE;

ADIPOCYTE; ADIPOSE TISSUE; BARIATRIC SURGERY; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL TRIAL; CYTOKINE PRODUCTION; CYTOTOXICITY; DIABETOGENESIS; DIET; ENDOPLASMIC RETICULUM STRESS; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLYCEMIC CONTROL; HEMATOPOIETIC CELL; HUMAN; HYPERGLYCEMIA; INFLAMMATION; INNATE IMMUNITY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOGENESIS; MACROPHAGE; MAST CELL; METABOLIC DISORDER; METABOLIC STRESS; METABOLIC SYNDROME X; MOLECULAR BIOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; WHITE ADIPOSE TISSUE; PATHOLOGY; PHYSIOLOGY;

HUMANS; I-KAPPA B KINASE; INFLAMMATION; METABOLIC DISEASES; MITOGEN-ACTIVATED PROTEIN KINASE 8; OBESITY;

EID: 77955806634     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-151340     Document Type: Review

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