-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J 2001 Global and societal implications of the diabetes epidemic. Nature 414:782-787
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
11144265737
-
The new concept of adipose tissue function
-
Hauner H 2004 The new concept of adipose tissue function. Physiol Behav 83:653-658
-
(2004)
Physiol Behav
, vol.83
, pp. 653-658
-
-
Hauner, H.1
-
4
-
-
0346880502
-
Molecular mechanisms of inflammation in obesity-linked insulin resistance
-
Marette A 2003 Molecular mechanisms of inflammation in obesity-linked insulin resistance. Int J Obes Relat Metab Disord 27:S46-S48
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
-
-
Marette, A.1
-
5
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H 2003 Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821-1830
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
6
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante Jr AW 2003 Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr, A.W.6
-
7
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
Taniguchi CM, Emanuelli B, Kahn CR 2006 Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 7:85-96
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
8
-
-
14544271905
-
Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
-
Gual P, Le Marchand-Brustel Y, Tanti JF 2005 Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. Biochimie (Paris) 87:99-109
-
(2005)
Biochimie (Paris)
, vol.87
, pp. 99-109
-
-
Gual, P.1
Le Marchand-Brustel, Y.2
Tanti, J.F.3
-
9
-
-
0035500813
-
Insulin resistance: A phosphorylation-based uncoupling of insulin signaling
-
Zick Y 2001 Insulin resistance: a phosphorylation-based uncoupling of insulin signaling. Trends Cell Biol 11:437-441
-
(2001)
Trends Cell Biol
, vol.11
, pp. 437-441
-
-
Zick, Y.1
-
10
-
-
0028023002
-
Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling
-
Tanti J-F, Grémeaux T, Van Obberghen E, Le Marchand-Brustel Y 1994 Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem 269:6051-6057
-
(1994)
J Biol Chem
, vol.269
, pp. 6051-6057
-
-
Tanti, J.-F.1
Grémeaux, T.2
Van Obberghen, E.3
Le Marchand-Brustel, Y.4
-
11
-
-
0034708832
-
The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307
-
Aguirre V, Uchida T, Yenush L, Davis R, White MF 2000 The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307. J Biol Chem 275:9047-9054
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
12
-
-
0035836770
-
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1
-
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB 2001 A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. Proc Natl Acad Sci USA 98:4640-4645
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4640-4645
-
-
Ozes, O.N.1
Akca, H.2
Mayo, L.D.3
Gustin, J.A.4
Maehama, T.5
Dixon, J.E.6
Donner, D.B.7
-
13
-
-
0344686538
-
MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632
-
Gual P, Gremeaux T, Gonzalez T, Le Marchand-Brustel Y, Tanti JF 2003 MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. Diabetologia 46:1532-1542
-
(2003)
Diabetologia
, vol.46
, pp. 1532-1542
-
-
Gual, P.1
Gremeaux, T.2
Gonzalez, T.3
Le Marchand-Brustel, Y.4
Tanti, J.F.5
-
14
-
-
0038321436
-
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes
-
Bouzakri K, Roques M, Gual P, Espinosa S, Guebre-Egziabher F, Riou JP, Laville M, Le Marchand-Brustel Y, Tanti JF, Vidal H 2003 Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes. Diabetes 52:1319-1325
-
(2003)
Diabetes
, vol.52
, pp. 1319-1325
-
-
Bouzakri, K.1
Roques, M.2
Gual, P.3
Espinosa, S.4
Guebre-Egziabher, F.5
Riou, J.P.6
Laville, M.7
Le Marchand-Brustel, Y.8
Tanti, J.F.9
Vidal, H.10
-
15
-
-
0033773334
-
Tumor necrosis factor α-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes
-
Engelman JA, Berg AH, Lewis RY, Lisanti MP, Scherer PE 2000 Tumor necrosis factor α-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. Mol Endocrinol 14:1557-1569
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1557-1569
-
-
Engelman, J.A.1
Berg, A.H.2
Lewis, R.Y.3
Lisanti, M.P.4
Scherer, P.E.5
-
16
-
-
0034717062
-
SOCS-3 is an insulin-induced negative regulator of insulin signaling
-
Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E 2000 SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem 275:15985-15991
-
(2000)
J Biol Chem
, vol.275
, pp. 15985-15991
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Sawka-Verhelle, D.4
Hilton, D.5
Van Obberghen, E.6
-
17
-
-
2942628012
-
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms
-
Ueki K, Kondo T, Kahn CR 2004 Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms. Mol Cell Biol 24:5434-5446
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5434-5446
-
-
Ueki, K.1
Kondo, T.2
Kahn, C.R.3
-
18
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
-
Rui L, Yuan M, Frantz D, Shoelson S, White MF 2002 SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 277:42394-42398
-
(2002)
J Biol Chem
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
19
-
-
33644782904
-
Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance
-
Shi H, Cave B, Inouye K, Bjorbaek C, Flier JS 2006 Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance. Diabetes 55:699-707
-
(2006)
Diabetes
, vol.55
, pp. 699-707
-
-
Shi, H.1
Cave, B.2
Inouye, K.3
Bjorbaek, C.4
Flier, J.S.5
-
20
-
-
0242580711
-
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells from insulin-resistant subjects
-
Rotter V, Nagaev I, Smith U 2003 Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278:45777-45784
-
(2003)
J Biol Chem
, vol.278
, pp. 45777-45784
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
21
-
-
0242299763
-
Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: Prevention by rosiglitazone
-
Lagathu C, Bastard JP, Auclair M, Maachi M, Capeau J, Caron M 2003 Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone. Biochem Biophys Res Commun 311:372-379
-
(2003)
Biochem Biophys Res Commun
, vol.311
, pp. 372-379
-
-
Lagathu, C.1
Bastard, J.P.2
Auclair, M.3
Maachi, M.4
Capeau, J.5
Caron, M.6
-
22
-
-
0038039463
-
Tumour necrosis factor α: A key regulator of adipose tissue mass
-
Warne JP 2003 Tumour necrosis factor α: a key regulator of adipose tissue mass. J Endocrinol 177:351-355
-
(2003)
J Endocrinol
, vol.177
, pp. 351-355
-
-
Warne, J.P.1
-
23
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
White MF 2002 IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283:E413-E422
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
White, M.F.1
-
24
-
-
33644514920
-
Tissue-specific roles of IRS proteins in insulin signaling and glucose transport
-
Thirone AC, Huang C, Klip A 2006 Tissue-specific roles of IRS proteins in insulin signaling and glucose transport. Trends Endocrinol Metab 17:72-78
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 72-78
-
-
Thirone, A.C.1
Huang, C.2
Klip, A.3
-
25
-
-
0037064536
-
Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family
-
Martin MU, Wesche H 2002 Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family. Biochim Biophys Acta 1592:265-280
-
(2002)
Biochim Biophys Acta
, vol.1592
, pp. 265-280
-
-
Martin, M.U.1
Wesche, H.2
-
26
-
-
0345700727
-
Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
-
Spranger J, Kroke A, Mohlig M, Hoffmann K, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF 2003 Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 52:812-817
-
(2003)
Diabetes
, vol.52
, pp. 812-817
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
Hoffmann, K.4
Bergmann, M.M.5
Ristow, M.6
Boeing, H.7
Pfeiffer, A.F.8
-
27
-
-
11144346107
-
Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome
-
Salmenniemi U, Ruotsalainen E, Pihlajamaki J, Vauhkonen I, Kainulainen S, Punnonen K, Vanninen E, Laakso M 2004 Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome. Circulation 110:3842-3848
-
(2004)
Circulation
, vol.110
, pp. 3842-3848
-
-
Salmenniemi, U.1
Ruotsalainen, E.2
Pihlajamaki, J.3
Vauhkonen, I.4
Kainulainen, S.5
Punnonen, K.6
Vanninen, E.7
Laakso, M.8
-
28
-
-
2942644669
-
Regulatory effects of interleukin (IL)-1, interferon-β, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue
-
Juge-Aubry CE, Somm E, Chicheportiche R, Burger D, Pernin A, Cuenod-Pittet B, Quinodoz P, Giusti V, Dayer JM, Meier CA 2004 Regulatory effects of interleukin (IL)-1, interferon-β, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue. J Clin Endocrinol Metab 89:2652-2658
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2652-2658
-
-
Juge-Aubry, C.E.1
Somm, E.2
Chicheportiche, R.3
Burger, D.4
Pernin, A.5
Cuenod-Pittet, B.6
Quinodoz, P.7
Giusti, V.8
Dayer, J.M.9
Meier, C.A.10
-
29
-
-
0347520946
-
A Crk-II/TC10 signaling pathway is required for osmotic shock-stimulated glucose transport
-
Gual P, Shigematsu S, Kanzali M, Grémeaux T, Gonzalez T, Pessin JE, Le Marchand-Brustel Y, Tanti J-F 2002 A Crk-II/TC10 signaling pathway is required for osmotic shock-stimulated glucose transport. J Biol Chem 277:43980-43986
-
(2002)
J Biol Chem
, vol.277
, pp. 43980-43986
-
-
Gual, P.1
Shigematsu, S.2
Kanzali, M.3
Grémeaux, T.4
Gonzalez, T.5
Pessin, J.E.6
Le Marchand-Brustel, Y.7
Tanti, J.-F.8
-
30
-
-
33646791194
-
The Rab4 effector Rabip4 plays a role in the endocytotic trafficking of Glut 4 in 3T3-L1 adipocytes
-
Mari M, Monzo P, Kaddai V, Keslair F, Gonzalez T, Le Marchand-Brustel Y, Cormont M 2006 The Rab4 effector Rabip4 plays a role in the endocytotic trafficking of Glut 4 in 3T3-L1 adipocytes. J Cell Sci 119:1297-1306
-
(2006)
J Cell Sci
, vol.119
, pp. 1297-1306
-
-
Mari, M.1
Monzo, P.2
Kaddai, V.3
Keslair, F.4
Gonzalez, T.5
Le Marchand-Brustel, Y.6
Cormont, M.7
-
31
-
-
0037422678
-
Stimulation of interleukin-6 release by interleukin-1β from isolated human adipocytes
-
Flower L, Gray R, Pinkney J, Mohamed-Ali V 2003 Stimulation of interleukin-6 release by interleukin-1β from isolated human adipocytes. Cytokine 21:32-37
-
(2003)
Cytokine
, vol.21
, pp. 32-37
-
-
Flower, L.1
Gray, R.2
Pinkney, J.3
Mohamed-Ali, V.4
-
32
-
-
28544435205
-
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
-
Eguez L, Lee A, Chavez JA, Miinea CP, Kane S, Lienhard GE, McGraw TE 2005 Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metab 2:263-272
-
(2005)
Cell Metab
, vol.2
, pp. 263-272
-
-
Eguez, L.1
Lee, A.2
Chavez, J.A.3
Miinea, C.P.4
Kane, S.5
Lienhard, G.E.6
McGraw, T.E.7
-
33
-
-
0037677096
-
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
-
Sano H, Kane S, Sano E, Miinea CP, Asara JM, Lane WS, Garner CW, Lienhard GE 2003 Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 278:14599-14602
-
(2003)
J Biol Chem
, vol.278
, pp. 14599-14602
-
-
Sano, H.1
Kane, S.2
Sano, E.3
Miinea, C.P.4
Asara, J.M.5
Lane, W.S.6
Garner, C.W.7
Lienhard, G.E.8
-
34
-
-
29444455533
-
Interleukin-1α inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes
-
He J, Usui I, Ishizuka K, Kanatani Y, Hiratani K, Iwata M, Bukhari A, Haruta T, Sasaoka T, Kobayashi M 2006 Interleukin-1α inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes. Mol Endocrinol 20:114-124
-
(2006)
Mol Endocrinol
, vol.20
, pp. 114-124
-
-
He, J.1
Usui, I.2
Ishizuka, K.3
Kanatani, Y.4
Hiratani, K.5
Iwata, M.6
Bukhari, A.7
Haruta, T.8
Sasaoka, T.9
Kobayashi, M.10
-
35
-
-
9444248788
-
The potential role of SOCS-3 in the interleukin-1β-induced desensitization of insulin signaling in pancreatic β-cells
-
Emanuelli B, Glondu M, Filloux C, Peraldi P, Van Obberghen E 2004 The potential role of SOCS-3 in the interleukin-1β-induced desensitization of insulin signaling in pancreatic β-cells. Diabetes 53:S97-S103
-
(2004)
Diabetes
, vol.53
-
-
Emanuelli, B.1
Glondu, M.2
Filloux, C.3
Peraldi, P.4
Van Obberghen, E.5
-
36
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM 1996 IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance. Science 271:665-668
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
37
-
-
33746736936
-
Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
-
Lagathu C, Yvan-Charvet L, Bastard JP, Maachi M, Quignard-Boulange A, Capeau J, Caron M 2006 Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes. Diabetologia 49:2162-2173
-
(2006)
Diabetologia
, vol.49
, pp. 2162-2173
-
-
Lagathu, C.1
Yvan-Charvet, L.2
Bastard, J.P.3
Maachi, M.4
Quignard-Boulange, A.5
Capeau, J.6
Caron, M.7
-
38
-
-
0028043899
-
Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells
-
Ohsumi J, Sakakibara S, Yamaguchi J, Miyadai K, Yoshioka S, Fujiwara T, Horikoshi H, Serizawa N 1994 Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells. Endocrinology 135:2279-2282
-
(1994)
Endocrinology
, vol.135
, pp. 2279-2282
-
-
Ohsumi, J.1
Sakakibara, S.2
Yamaguchi, J.3
Miyadai, K.4
Yoshioka, S.5
Fujiwara, T.6
Horikoshi, H.7
Serizawa, N.8
-
39
-
-
0034671645
-
Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo
-
Previs SF, Withers DJ, Ren JM, White MF, Shulman GI 2000 Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo. J Biol Chem 275:38990-38994
-
(2000)
J Biol Chem
, vol.275
, pp. 38990-38994
-
-
Previs, S.F.1
Withers, D.J.2
Ren, J.M.3
White, M.F.4
Shulman, G.I.5
-
40
-
-
21444460644
-
Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes
-
Huang C, Thirone AC, Huang X, Klip A 2005 Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes. J Biol Chem 280:19426-19435
-
(2005)
J Biol Chem
, vol.280
, pp. 19426-19435
-
-
Huang, C.1
Thirone, A.C.2
Huang, X.3
Klip, A.4
-
41
-
-
0037341276
-
Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: Potential role of p38 in the downregulation of GLUT4 expression
-
Carlson CJ, Koterski S, Sciotti RJ, Poccard GB, Rondinone CM 2003 Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression. Diabetes 52:634-641
-
(2003)
Diabetes
, vol.52
, pp. 634-641
-
-
Carlson, C.J.1
Koterski, S.2
Sciotti, R.J.3
Poccard, G.B.4
Rondinone, C.M.5
-
42
-
-
0037339991
-
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes
-
Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Abe M, Shojima N, Fukushima Y, Kikuchi M, Oka Y, Asano T 2003 Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol 17:487-497
-
(2003)
Mol Endocrinol
, vol.17
, pp. 487-497
-
-
Fujishiro, M.1
Gotoh, Y.2
Katagiri, H.3
Sakoda, H.4
Ogihara, T.5
Anai, M.6
Onishi, Y.7
Ono, H.8
Abe, M.9
Shojima, N.10
Fukushima, Y.11
Kikuchi, M.12
Oka, Y.13
Asano, T.14
-
43
-
-
33644785016
-
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients
-
Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR 2006 IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. Diabetes 55:785-791
-
(2006)
Diabetes
, vol.55
, pp. 785-791
-
-
Bouzakri, K.1
Karlsson, H.K.2
Vestergaard, H.3
Madsbad, S.4
Christiansen, E.5
Zierath, J.R.6
-
44
-
-
5644301067
-
Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-α induction of p38 and p42/p44 mitogen-activated protein kinases
-
Hernandez R, Teruel T, de Alvaro C, Lorenzo M 2004 Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-α induction of p38 and p42/p44 mitogen-activated protein kinases. Diabetologia 47:1615-1624
-
(2004)
Diabetologia
, vol.47
, pp. 1615-1624
-
-
Hernandez, R.1
Teruel, T.2
de Alvaro, C.3
Lorenzo, M.4
-
45
-
-
25844456730
-
Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
-
Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK 2005 Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes 54:2939-2945
-
(2005)
Diabetes
, vol.54
, pp. 2939-2945
-
-
Plomgaard, P.1
Bouzakri, K.2
Krogh-Madsen, R.3
Mittendorfer, B.4
Zierath, J.R.5
Pedersen, B.K.6
-
46
-
-
19944433322
-
The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis
-
Bost F, Aouadi M, Caron L, Even P, Belmonte N, Prot M, Dani C, Hofman P, Pages G, Pouyssegur J, Le Marchand-Brustel Y, Binetruy B 2005 The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes 54:402-411
-
(2005)
Diabetes
, vol.54
, pp. 402-411
-
-
Bost, F.1
Aouadi, M.2
Caron, L.3
Even, P.4
Belmonte, N.5
Prot, M.6
Dani, C.7
Hofman, P.8
Pages, G.9
Pouyssegur, J.10
Le Marchand-Brustel, Y.11
Binetruy, B.12
-
47
-
-
0034463918
-
A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1
-
Haruta T, Uno T, Kawahara J, Takano A, Egawa K, Sharma PM, Olefsky JM, Kobayashi M 2000 A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. Mol Endocrinol 14:783-794
-
(2000)
Mol Endocrinol
, vol.14
, pp. 783-794
-
-
Haruta, T.1
Uno, T.2
Kawahara, J.3
Takano, A.4
Egawa, K.5
Sharma, P.M.6
Olefsky, J.M.7
Kobayashi, M.8
-
48
-
-
0034947869
-
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
-
Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M 2001 Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin. Mol Cell Biol 21:5050-5062
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5050-5062
-
-
Takano, A.1
Usui, I.2
Haruta, T.3
Kawahara, J.4
Uno, T.5
Iwata, M.6
Kobayashi, M.7
-
49
-
-
0038712570
-
Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes
-
Gual P, Gonzalez T, Gremeaux T, Barres R, Le Marchand-Brustel Y, Tanti JF 2003 Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes. J Biol Chem 278:26550-26557
-
(2003)
J Biol Chem
, vol.278
, pp. 26550-26557
-
-
Gual, P.1
Gonzalez, T.2
Gremeaux, T.3
Barres, R.4
Le Marchand-Brustel, Y.5
Tanti, J.F.6
-
50
-
-
0038691609
-
IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress
-
Potashnik R, Bloch-Damti A, Bashan N, Rudich A 2003 IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress. Diabetologia 46:639-648
-
(2003)
Diabetologia
, vol.46
, pp. 639-648
-
-
Potashnik, R.1
Bloch-Damti, A.2
Bashan, N.3
Rudich, A.4
-
51
-
-
33646041304
-
Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes
-
He F, Stephens JM 2006 Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes. Biochem Biophys Res Commun 344:95-98
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 95-98
-
-
He, F.1
Stephens, J.M.2
-
52
-
-
0034635550
-
Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1β on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells
-
Boisclair YR, Wang J, Shi J, Hurst KR, Ooi GT 2000 Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1β on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells. J Biol Chem 275:3841-3847
-
(2000)
J Biol Chem
, vol.275
, pp. 3841-3847
-
-
Boisclair, Y.R.1
Wang, J.2
Shi, J.3
Hurst, K.R.4
Ooi, G.T.5
|