Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

Cell

Volumn 135, Issue 1, 2008, Pages 61-73

  Zhang, Xiaoqing ^a   Zhang, Guo ^a   Zhang, Hai ^a   Karin, Michael ^b   Bai, Hua ^a   Cai, Dongsheng ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

HUMDISEASE; SYSNEURO

Indexed keywords

AGOUTI RELATED PROTEIN; BETA ACTIN; GREEN FLUORESCENT PROTEIN; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; INSULIN; LEPTIN; PROTEIN KINASE B; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR SP1; AGOUTI RELATED PROTEIN, MOUSE; AGOUTI-RELATED PROTEIN, MOUSE; I KAPPA B; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CELL STRESS; CHRONIC INFLAMMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENERGY BALANCE; ENZYME ACTIVATION; ENZYME REPRESSION; ENZYME SPECIFICITY; GLUCOSE INTOLERANCE; HYPOTHALAMUS; METABOLIC REGULATION; MOUSE; NONHUMAN; OBESITY; OVERNUTRITION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; ENERGY METABOLISM; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; INSULIN RESISTANCE; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY;

AGOUTI-RELATED PROTEIN; ANIMALS; ENDOPLASMIC RETICULUM; ENERGY METABOLISM; HUMANS; HYPOTHALAMUS; I-KAPPA B PROTEINS; IMMUNITY, NATURAL; INSULIN RESISTANCE; MICE; MICE, INBRED C57BL; NEURONS; NF-KAPPA B; OBESITY; OVERNUTRITION; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 52949096557     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.07.043     Document Type: Article

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