A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways

Journal of Biological Chemistry

Volumn 282, Issue 48, 2007, Pages 35279-35292

  Nguyen, M T Audrey ^a   Favelyukis, Svetlana ^a   Nguyen, Anh Khoi ^a   Reichart, Donna ^b   Scott, Peter A ^a   Jenn, Alan ^a   Liu Bryan, Ru ^a   Glass, Christopher K ^b   Neels, Jaap G ^a   Olefsky, Jerrold M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACIDS; INSULIN; MUSCLE; PHOSPHORYLATION;

ADIPOSE TISSUE (AT); INSULIN RESISTANCE; MACROPHAGE INFILTRATION;

MACROPHAGES;

CD11 ANTIGEN; CD11B ANTIGEN; FATTY ACID; GLYCOPROTEIN P 15095; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADIPOSE TISSUE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL INFILTRATION; CELL SUBPOPULATION; CONTROLLED STUDY; DENDRITIC CELL; HYPERTROPHY; INSULIN RESISTANCE; MACROPHAGE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADIPOSE TISSUE; ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD11C; BONE MARROW CELLS; FATTY ACIDS, NONESTERIFIED; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGES; MALE; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

MUS;

EID: 36849005372     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706762200     Document Type: Article

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