메뉴 건너뛰기




Volumn 30, Issue 1 SUPPL. B, 2002, Pages

The IKK/NF-κB pathway

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; PROTEIN P50; PROTEIN P52; TUMOR NECROSIS FACTOR;

EID: 0036162459     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200201001-00003     Document Type: Conference Paper
Times cited : (274)

References (124)
  • 2
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 7
    • 0033600604 scopus 로고    scopus 로고
    • The beginning of the end: I kappa B kinase (IKK) and NF-kappa B activation
    • (1999) J Biol Chem , vol.274 , pp. 27339-27342
    • Karin, M.1
  • 13
  • 15
    • 0028982263 scopus 로고
    • Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105: Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation
    • (1995) J Biol Chem , vol.270 , pp. 21707-21714
    • Orian, A.1    Whiteside, S.2    Israel, A.3
  • 23
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IkappaB phosphorylation and NFkappaB activation
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3
  • 25
  • 27
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the I kappa B kinase complex essential for NF-kappa B activation
    • (1998) Cell , vol.93 , pp. 1231-1240
    • Yamaoka, S.1    Courtois, G.2    Bessia, C.3
  • 28
    • 0032575379 scopus 로고    scopus 로고
    • Direct phosphorylation of IkappaB by IKKalpha and IKK-beta: Discrimination between free and NFkappaB-bound substrate
    • (1998) Science , vol.281 , pp. 1360-1363
    • Zandi, E.1    Chen, Y.2    Karin, H.3
  • 31
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of rel/ NF-kappaB transcription factors
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 32
    • 0033532386 scopus 로고    scopus 로고
    • The IKK beta subunit of I kappa B kinase (IKK) is essential for nuclear factor kappa B activation and prevention of apoptosis
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.M.2    Hu, Y.L.3
  • 36
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKK alpha subunit of I kappa B kinase
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.L.1    Baud, V.2    Delhase, M.3
  • 43
    • 0030731146 scopus 로고    scopus 로고
    • Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase
    • (1997) EMBO J , vol.16 , pp. 6486-6494
    • Yaron, A.1    Gonen, H.2    Alkalay, I.3
  • 49
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappaB/Rel family
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3
  • 50
    • 0030615259 scopus 로고    scopus 로고
    • p50-NF-kappa B complexes partially compensate for the absence of relB: Severely increased pathology in p50(-/-)relB(-/-) double-knockout mice
    • (1997) J Exp Med , vol.185 , pp. 1359-1370
    • Weih, F.1    Durham, S.K.2    Barton, D.S.3
  • 52
    • 0030999057 scopus 로고    scopus 로고
    • NF-kappa B RelA-deficient lymphocytes: Normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses
    • (1997) J Exp Med , vol.185 , pp. 953-961
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3
  • 53
    • 0031964855 scopus 로고    scopus 로고
    • Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
    • (1998) J Exp Med , vol.187 , pp. 147-159
    • Franzoso, G.1    Carlson, L.2    Poljak, L.3
  • 56
    • 0032489828 scopus 로고    scopus 로고
    • Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappa B1) but expressing p50
    • (1998) J Exp Med , vol.187 , pp. 985-996
    • Ishikawa, H.1    Claudio, E.2    Dambach, D.3
  • 60
    • 0035424999 scopus 로고    scopus 로고
    • Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment
    • (2001) J Immunol , vol.167 , pp. 1592-1600
    • Alcamo, E.1    Mizgerd, J.P.2    Horwitz, B.H.3
  • 62
    • 0035809983 scopus 로고    scopus 로고
    • IKKalpha controls formation of the epidermis independently of NF-kappaB
    • (2001) Nature , vol.410 , pp. 710-714
    • Hu, Y.1    Baud, V.2    Oga, T.3
  • 69
    • 0028971291 scopus 로고
    • Constitutive NF-kappaB activation, enhanced granulopoiesis, and neonatal lethality in I-kappaBalpha-deficient mice
    • (1995) Genes Dev , vol.9 , pp. 2736-2746
    • Beg, A.1    Sha, W.C.2    Bronson, R.T.3
  • 73
    • 0031975585 scopus 로고    scopus 로고
    • Regulation of immune responses by NF-kappa B/Rel transcription factors
    • (1998) J Exp Med , vol.187 , pp. 143-146
    • Sha, W.C.1
  • 75
    • 0029595394 scopus 로고
    • Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells
    • (1995) J Biol Chem , vol.270 , pp. 31315-31320
    • Yamamoto, K.1    Arakawa, T.2    Ueda, N.3
  • 80
    • 0027379055 scopus 로고
    • NF-kappa B, cooperativity between C/EBP, Baldwin AS Jr Distinct mechanisms for regulation of the interleukin-8 gene involve synergism
    • (1993) Mol Cell Biol , vol.13 , pp. 7191-7198
    • Stein, B.1
  • 86
    • 0028948176 scopus 로고
    • Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes: IL-10 anal IL-4 suppress cytokine synthesis by different mechanisms
    • (1995) J Biol Chem , vol.270 , pp. 9558-9563
    • Wang, P.1    Wu, P.2    Siegel, M.I.3
  • 91
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3
  • 94
    • 0028841622 scopus 로고
    • NF-kappaB, reoxigenation Differential activation of transcription factors AP-1, Baeuerle PA The genomic response of tumor cells to hypoxia
    • (1995) Eur J Biochem , vol.234 , pp. 632-640
    • Rupec, R.A.1
  • 104
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
    • (1995) J Clin Invest , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3
  • 105
  • 106
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • (1991) EMBO J , vol.10 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 107
  • 109
    • 0032797974 scopus 로고    scopus 로고
    • Use of genetically altered mice to investigate the role of nuclear factor-kappa B activation and cytokine gene expression in sepsis-induced ARDS
    • (1999) Chest , vol.116
    • Blackwell, T.S.1    Yull, F.E.2    Chen, C.L.3
  • 110
    • 0032917428 scopus 로고    scopus 로고
    • Early activation of pulmonary nuclear factor kappaB and nuclear factor interleukin-6 in polymicrobial sepsis
    • (1999) J Trauma , vol.46 , pp. 590-596
    • Browder, W.1    Ha, T.2    Chuanfu, L.3
  • 113
    • 0033866838 scopus 로고    scopus 로고
    • Pancreatic elastase activates pulmonary nuclear factor kappa B and inhibitory kappa B, mimicking pancreatitis-associated adult respiratory distress syndrome
    • (2000) Surgery , vol.128 , pp. 225-231
    • Jaffray, C.1    Yang, J.2    Carter, G.3
  • 118


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.