Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

Molecular Cell

Volumn 34, Issue 3, 2009, Pages 285-297

  Callén, Elsa ^a   Jankovic, Mila ^b   Wong, Nancy ^a   Zha, Shan ^c   Chen, Hua Tang ^a   Difilippantonio, Simone ^a   Di Virgilio, Michela ^b   Heidkamp, Gordon ^b   Alt, Frederick W ^c   Nussenzweig, André ^a   Nussenzweig, Michel ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

DNA; MOLIMMUNO; PROTEINS

Indexed keywords

ATM PROTEIN; DNA; DOUBLE STRANDED DNA; IMMUNOGLOBULIN; PROTEIN KINASE; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CATALYSIS; CELL DEATH; CHROMOSOME; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; GENE INSERTION; LYMPHOCYTE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FIBROBLASTS; GENOMIC INSTABILITY; IMMUNOGLOBULIN CLASS SWITCHING; LYMPHOCYTES; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 65549111779     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.04.025     Document Type: Article

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