Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

Science

Volumn 280, Issue 5366, 1998, Pages 1089-1091

  Herzog, Karl Heinz ^a   Chong, Miriam J ^a   Kapsetaki, Manuela ^a   Morgan, James I ^a   McKinnon, Peter J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; BRAIN DEVELOPMENT; CELL DEATH; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IONIZING RADIATION; NERVE DEGENERATION; PRIORITY JOURNAL; RADIATION HAZARD; SURVIVAL RATE;

ANIMALS; APOPTOSIS; BRAIN; CELL CYCLE PROTEINS; CEREBELLUM; DNA-BINDING PROTEINS; GENES, P53; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RADIATION, IONIZING; RETINA; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0032524070     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.280.5366.1089     Document Type: Article

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38. -/- mice, and S. J. Baker for comments on the manuscript. Supported by the AT Children's Project (P.J.McK.), Cancer Center CORE grant CA-21765, and by the American Lebanese and Syrian Associated Charities (ALSAC) of St. Jude Children's Research Hospital.