A comprehensive study of p53 transcriptional activity in thymus and spleen of γ irradiated mouse: High sensitivity of genes involved in the two main apoptotic pathways

International Journal of Radiation Biology

Volumn 82, Issue 11, 2006, Pages 761-770

  Alvarez, Sandra ^a,b   Drané, Pascal ^a,b   Meiller, Anne ^a,c   Bras, Marlene ^a   Deguin Chambon, Valerie ^a,d   Bouvard, Veronique ^a,e   May, Evelyne ^a,b  

^a CNRS   (France)

^b INSTITUT ANDRÉ LWOFF   (France)

^c UNIVERSITÉ LYON 1   (France)

^d INSTITUT CURIE   (France)

^e INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

irradiation; Apoptosis; In vivo; Mouse; p53; Transcription

Indexed keywords

DEATH RECEPTOR 5; FAS ANTIGEN; PROTEIN BAX; PROTEIN NOXA; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GAMMA IRRADIATION; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RADIATION DOSE; RADIATION EXPOSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SENSITIVITY ANALYSIS; THYMUS; TRANSCRIPTION INITIATION; UPREGULATION; WHOLE BODY RADIATION;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RNA, MESSENGER; SPLEEN; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; WHOLE-BODY IRRADIATION;

EID: 33845508442     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.1080/09553000600949624     Document Type: Article

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