The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 8, 2007, Pages 2843-2848

  Kiefer, Kerstin ^a,b   Oshinsky, Jennifer ^a   Kim, Jiyoon ^a   Nakajima, Pamela B ^a   Bosma, Gayle C ^a   Bosma, Melvin J ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Ig transgenic mice; V(D)J recombination

Indexed keywords

COMPLEMENTARY DNA; DNA DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN HEAVY CHAIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CATALYSIS; CLASS SWITCH RECOMBINATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBUNIT; FLOW CYTOMETRY; GENE SWITCHING; GENETIC RECOMBINATION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE; TRANSGENIC MOUSE; WESTERN BLOTTING;

ADOPTIVE TRANSFER; ANIMALS; B-LYMPHOCYTES; BONE MARROW CELLS; BREEDING; CATALYTIC DOMAIN; CELL COUNT; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENOTYPE; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; MICE; MICE, SCID; MICE, TRANSGENIC; NUCLEAR PROTEINS; RECOMBINATION, GENETIC; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND; TRANSGENES;

MUS; MUS MUSCULUS;

EID: 33847276659     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611359104     Document Type: Article

References (53)

1. Honjo T, Kinoshita K, Muramatsu M (2002) Annu Rev Immunol 20:165-196.
2. Dudley DD, Chaudhuri J, Bassing CH, Alt FW (2005) Adv Immunnol 86:43-112.
3. Jung D, Giallourakis C, Mostoslavsky R, Alt FW (2006) Annu Rev Immunol 24:541-570.
4. Gellert M (2002) Annu Rev Biochem 71:101-132.
5. Manis JP, Gu Y, Lansford R, Sonoda E, Ferrini R, Davidson L, Rajewsky K, Alt FW (1998) J Exp Med 187:2081-2089.
6. Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H, Qin X-F, Kenter A, Rajewsky K, Nussenzweig M (1998) EMBO J 17:2404-2411.
7. Rolink A, Melchers F, Andersson J (1996) Immunity 5:319-330.
8. Manis JP, Dudley D, Kaylor L, Alt FW (2002) Immunity 16:607-617.
9. Reina-San-Martin B, Difilippantonio S, Hanitsch L, Masilamani RF, Nussenzweig A, Nussenzweig MC (2003) J Exp Med 197:1767-1778.
10. Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, Depinho RA, Alt FW (2000) Proc Natl Acad Sci USA 97:6630-6633.
11. Bosma GC, Kim J, Urich T, Path DM, Cotticelli MG, Ruetsch NR, Radic MZ, Bosma MJ (2002) J Exp Med 196:1483-1495.
12. Cook AJL, Oganesian L, Harumal P, Basten A, Brink R, Jolly CJ (2003) J Immunol 171:6556-6564.
13. Danska J, Holland DP, Mariathasan S, Williams KM, Guidos CJ (1996) Mol Cell Biol 16:5507-5517.
14. Blunt T, Gell D, Fox M, Taccioli GE, Lehmann AR, Jackson SP, Jeggo PA (1996) Proc Natl Acad Sci USA 93:10285-10290.
15. Grawunder U, Finnic N, Jackson S, Riwar B, Jessberger R (1996) Eur J Biochem 241:931-940.
16. Beamish HJ, Jessberger R, Riballo E, Priestley A, Blunt T, Kysela B, Jeggo PA (2000) Nucleic Acids Res 28:1506-1513.
17. Meek K, Gupta S, Ramsden DA, Lees-Miller SP (2004) Immunol Rev 200:132-141.
18. Lee KJ, Huang J, Takeda Y, Dynan WS (2000) J Biol Chem 275:34787-34796.
19. Weterings E, Verkaik NS, Bruggenwirth HT, Hoeijmakers JH, van Gent DC (2003) Nucleic Acids Res 31:7238-7246.
20. Kurimasa A, Kumano S, Boubnov N, Story MD, Tung C-S, Peterson SR, Chen DJ (1999) Mol Cell Biol 19:3877-3884.
21. Kienker LJ, Shin EK, Meek K (2000) Nucleic Acids Res 28:2752-2761.
22. Erikson J, Radic MZ, Camper SA, Hardy RR, Carmack C, Weigert M (1991) Nature 349:331-334.
23. Chen C, Nagy S, Prak EL, Weigert M (1995) Immunity 3:747-755.
24. Carmack CE, Camper SA, Mackle JJ, Gerhard WU, Weigert MG (1991) J Immunol 147:2024-2033.
25. Prak EL, Weigert M (1995) J Exp Med 182:541-548.
26. Nguyen K-AT, Mandik L, Bui A, Ravaler J, Norvell A, Monroe JG, Roark JH, Erikson J (1997) J Immunol 159:2633-2644.
27. Taccioli GE, Amatucci AG, Beamish HJ, Gell D, Xiang XH, Torres Arzayus MI, Priestley A, Jackson SP, Marshak Rothstein A, et al. (1998) Immunity 9:355-366.
28. Maruyama C, Suemizu H, Tamamushi S, Kimoto S, Tamaoki N, Ohnishi Y (2002) Exp Anim 51:391-393.
29. Lansford R, Manis JP, Sonoda E, Rajewsky K, Alt FW (1998) Int Immunol 10:325-332.
30. Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T (2000) Cell 102:553-563.
31. Kataoka T, Miyata T, Honjo T (1981) Cell 23:357-368.
32. Nikaido T, Yamawaki-Kataoka Y, Honjo T (1982) J Biol Chem 257:7322-7329.
33. Szurek P, Petrini J, Dunnick W (1985) J Immunol 135:620-626.
34. Mowatt MR, Dunnick W (1986) J Immunol 136:2674-2683.
35. Bosma GC, Oshinsky J, Kiefer K, Nakajima PB, Charan D, Congelton C, Radic M, Bosma MJ (2006) J Immunol 176:889-898.
36. Harrington J, Hsieh CL, Gerton J, Bosma G, Lieber MR (1992) Mol Cell Biol 12:4758-4768.
37. Lieber MR, Hesse JE, Lewis S, Bosma GC, Rosenberg N, Mizuuchi K, Bosma MJ, Gellert M (1988) Cell 55:7-16.
38. Taccioli GE, Rathbun G, Oltz E, Stamato T, Jeggo PA, Alt FW (1993) Science 260:207-210.
39. Carroll AM, Slack JK, Chang W-T (1993) Mol Cell Biol 13:3632-3640.
40. Bogue MA, Jhappan C, Roth DB (1998) Proc Natl Acad Sci USA 95:15559-15564.
41. Roth DB (2003) Nat Rev Immunol 3:656-666.
42. Moshous D, Li L, de Chasseval R, Philippe N, Jabado N, Cowan MJ, Fischer A, de Villartay JP (2000) Hum Mol Genet 9:583-588.
43. Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F, Tezcan I, Sanal O, Bertrand Y, Philippe N, et al. (2001) Cell 105:177-186.
44. Ma Y, Pannicke U, Schwarz K, Lieber MR (2002) Cell 108:781-794.
45. Soubeyrand S, Pope L, De Chasseval R, Gosselin D, Dong F, de Villartay JP, Hache RJ (2006) J Mol Biol 358:1200-1211.
46. Goodarzi AA, Yu Y, Riballo E, Douglas P, Walker SA, Ye R, Harer C, Marchetti C, Morrice N, Jeggo PA, Lees-Miller SP (2006) EMBO J 25:3880-3889.
47. Wuerffel RA, Jian D, Thompson RJ, Kenter AL (1997) J Immunol 159:4139-4144.
48. Rush JS, Fugmann SD, Schatz DG (2004) Int Immunol 16:549-557.
49. Schrader CE, Edelmann W, R. K., Stavnezer J (1999) J Exp Med 190:323-330.
50. Spanopoulou E, Roman CAJ, Corcoran LM, Schlissel MS, Silver DP, Nemazee D, Nussenzweig M, Shinton SA, Hardy RR, Baltimore D (1994) Genes Dev 8:1030-1042.
51. Li Y-S, Hayakawa K, Hardy RR (1993) J Exp Med 178:951-960.
52. Chen J, Trounstine M, Kurahara C, Young F, Kuo C-C, Xu Y, Loring JF, Alt FW, Huszar D (1993) EMBO J 12:821-830.
53. Chang Y, Bosma MJ, Bosma GC (1999) J Exp Med 189:1295-1305.