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Volumn 18, Issue 12, 2004, Pages 1423-1438

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

Author keywords

ATM; BRCA1; DNA damage; NBS1; SMC1

Indexed keywords

ATM PROTEIN; BRCA1 PROTEIN; DNA; NIBRIN; PROTEIN; PROTEIN KINASE; SMC1 PROTEIN; UNCLASSIFIED DRUG;

EID: 2942687831     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1200304     Document Type: Article
Times cited : (358)

References (43)
  • 2
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist, C.J. and Kastan, M.B. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 4
    • 0028171182 scopus 로고
    • The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia
    • Canman, C.E., Wolff, A.C., Chen, C.Y., Fornace Jr., A.J., and Kastan, M.B. 1994. The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Res. 54: 5054-5058.
    • (1994) Cancer Res. , vol.54 , pp. 5054-5058
    • Canman, C.E.1    Wolff, A.C.2    Chen, C.Y.3    Fornace Jr., A.J.4    Kastan, M.B.5
  • 8
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
    • Cortez, D., Wang, Y., Qin, J., and Elledge, S.J. 1999. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 286: 1162-1166.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3    Elledge, S.J.4
  • 10
    • 2942698178 scopus 로고    scopus 로고
    • The Rad17-Atr-Smc1 pathway is essential for ultraviolet radiation induced S-phase arrest
    • in press
    • Garg, R., Callens, S., Lim, D-S., Canman, C.E., Kastan, M.B., and Xu, B. 2004. The Rad17-Atr-Smc1 pathway is essential for ultraviolet radiation induced S-phase arrest. Mol. Cancer Res. (in press).
    • (2004) Mol. Cancer Res.
    • Garg, R.1    Callens, S.2    Lim, D.-S.3    Canman, C.E.4    Kastan, M.B.5    Xu, B.6
  • 11
    • 0037142619 scopus 로고    scopus 로고
    • Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest
    • Girard, P.M., Riballo, E., Begg, A.C., Waugh, A., and Jeggo, P.A. 2002. Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene 21: 4191-4199.
    • (2002) Oncogene , vol.21 , pp. 4191-4199
    • Girard, P.M.1    Riballo, E.2    Begg, A.C.3    Waugh, A.4    Jeggo, P.A.5
  • 12
    • 2442444916 scopus 로고    scopus 로고
    • Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation
    • Horejsi, Z., Falck, J., Bakkenist, C., Kastan, M., Lukas, J., and Bartek, J. 2004. Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. Oncogene 23: 3122-3127.
    • (2004) Oncogene , vol.23 , pp. 3122-3127
    • Horejsi, Z.1    Falck, J.2    Bakkenist, C.3    Kastan, M.4    Lukas, J.5    Bartek, J.6
  • 13
    • 0027320551 scopus 로고
    • A mammalian protein complex that repairs double-strand breaks and deletions by recombination
    • Jessberger, R., Podust, V., Hubscher, U., and Berg, P. 1993. A mammalian protein complex that repairs double-strand breaks and deletions by recombination. J. Biol. Chem. 268: 15070-15079.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15070-15079
    • Jessberger, R.1    Podust, V.2    Hubscher, U.3    Berg, P.4
  • 14
    • 0029782098 scopus 로고    scopus 로고
    • SMC proteins constitute two subunits of the mammalian recombination complex RC-1
    • Jessberger, R., Riwar, B., Baechtold, H., and Akhmedov, A.T. 1996. SMC proteins constitute two subunits of the mammalian recombination complex RC-1. EMBO J. 15: 4061-4068.
    • (1996) EMBO J. , vol.15 , pp. 4061-4068
    • Jessberger, R.1    Riwar, B.2    Baechtold, H.3    Akhmedov, A.T.4
  • 15
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M.B. and Lim, D.S. 2000. The many substrates and functions of ATM. Nat. Rev. Mol. Cell. Biol. 1: 179-186.
    • (2000) Nat. Rev. Mol. Cell. Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 16
    • 0036500555 scopus 로고    scopus 로고
    • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
    • Kim, S.T., Xu, B., and Kastan, M.B. 2002. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes & Dev. 16: 560-570.
    • (2002) Genes & Dev. , vol.16 , pp. 560-570
    • Kim, S.T.1    Xu, B.2    Kastan, M.B.3
  • 17
    • 0036337593 scopus 로고    scopus 로고
    • In vivo site-directed mutagenesis of yeast plasmids using a three-fragment homologous recombination system
    • Kitagawa, K. and Abdulle, R. 2002. In vivo site-directed mutagenesis of yeast plasmids using a three-fragment homologous recombination system. Biotechniques 33: 288, 290, 292 passim.
    • (2002) Biotechniques , vol.33 , pp. 288
    • Kitagawa, K.1    Abdulle, R.2
  • 18
    • 1842431822 scopus 로고    scopus 로고
    • Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
    • Lee, J.H. and Paull, T.T. 2004. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 304: 93-96.
    • (2004) Science , vol.304 , pp. 93-96
    • Lee, J.H.1    Paull, T.T.2
  • 19
    • 12444254801 scopus 로고    scopus 로고
    • Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage
    • Lee, J.H., Xu, B., Lee, C.H., Ahn, J.Y., Song, M.S., Lee, H., Canman, C.E., Lee, J.S., Kastan, M.B., and Lim, D.S. 2003. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol. Cancer Res. 1: 674-681.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 674-681
    • Lee, J.H.1    Xu, B.2    Lee, C.H.3    Ahn, J.Y.4    Song, M.S.5    Lee, H.6    Canman, C.E.7    Lee, J.S.8    Kastan, M.B.9    Lim, D.S.10
  • 22
    • 0030885925 scopus 로고    scopus 로고
    • Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
    • Michaelis, C., Ciosk, R., and Nasmyth, K. 1997. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids. Cell 91: 35-45.
    • (1997) Cell , vol.91 , pp. 35-45
    • Michaelis, C.1    Ciosk, R.2    Nasmyth, K.3
  • 23
    • 0034749425 scopus 로고    scopus 로고
    • DNA damage-dependent nuclear dynamics of the Mre11 complex
    • Mirzoeva, O.K. and Petrini, J.H. 2001. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol. Cell. Biol. 21: 281-288.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 281-288
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 24
    • 0037226818 scopus 로고    scopus 로고
    • DNA replication-dependent nuclear dynamics of the Mre11 complex
    • -. 2003. DNA replication-dependent nuclear dynamics of the Mre11 complex. Mol. Cancer Res. 1: 207-218.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 207-218
  • 25
    • 0346059615 scopus 로고    scopus 로고
    • 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage
    • Mochan, T.A., Venere, M., DiTullio Jr., R.A., and Halazonetis, T.D. 2003. 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. Cancer Res. 63: 8586-8591.
    • (2003) Cancer Res. , vol.63 , pp. 8586-8591
    • Mochan, T.A.1    Venere, M.2    DiTullio Jr., R.A.3    Halazonetis, T.D.4
  • 26
    • 0030969423 scopus 로고    scopus 로고
    • Fragments of ATM which have dominant-negative or complementing activity
    • Morgan, S.E., Lovly, C., Pandita, T.K., Shiloh, Y., and Kastan, M.B. 1997. Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol. 17: 2020-2029.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2020-2029
    • Morgan, S.E.1    Lovly, C.2    Pandita, T.K.3    Shiloh, Y.4    Kastan, M.B.5
  • 27
    • 0041660970 scopus 로고    scopus 로고
    • ATM-related Tell associates with double-strand breaks through an Xrs2-dependent mechanism
    • Nakada, D., Matsumoto, K., and Sugimoto, K. 2003. ATM-related Tell associates with double-strand breaks through an Xrs2-dependent mechanism. Genes & Dev. 17: 1957-1962.
    • (2003) Genes & Dev. , vol.17 , pp. 1957-1962
    • Nakada, D.1    Matsumoto, K.2    Sugimoto, K.3
  • 28
    • 0026733077 scopus 로고
    • The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia
    • Pandita, T.K. and Hittelman, W.N. 1992. The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia. Radiat. Res. 131: 214-223.
    • (1992) Radiat. Res. , vol.131 , pp. 214-223
    • Pandita, T.K.1    Hittelman, W.N.2
  • 29
    • 0030833568 scopus 로고    scopus 로고
    • BRCA1 is a cell cycle-regulated nuclear phosphoprotein
    • Ruffner, H. and Verma, I.M. 1997. BRCA1 is a cell cycle-regulated nuclear phosphoprotein. Proc. Natl. Acad. Sci. 94: 7138-7143.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 7138-7143
    • Ruffner, H.1    Verma, I.M.2
  • 30
    • 0034798285 scopus 로고    scopus 로고
    • ATM: Genome stability, neuronal development, and cancer cross paths
    • Shiloh, Y. and Kastan, M.B. 2001. ATM: Genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res. 83: 209-254.
    • (2001) Adv. Cancer Res. , vol.83 , pp. 209-254
    • Shiloh, Y.1    Kastan, M.B.2
  • 32
    • 0035954251 scopus 로고    scopus 로고
    • Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae
    • Sjogren, C. and Nasmyth, K. 2001. Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr. Biol. 11: 991-995.
    • (2001) Curr. Biol. , vol.11 , pp. 991-995
    • Sjogren, C.1    Nasmyth, K.2
  • 33
    • 0027893001 scopus 로고
    • Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
    • Slichenmyer, W.J., Nelson, W.G., Slebos, R.J., and Kastan, M.B. 1993. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53: 4164-4168.
    • (1993) Cancer Res. , vol.53 , pp. 4164-4168
    • Slichenmyer, W.J.1    Nelson, W.G.2    Slebos, R.J.3    Kastan, M.B.4
  • 35
    • 0033522135 scopus 로고    scopus 로고
    • Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1
    • Stursberg, S., Riwar, B., and Jessberger, R. 1999. Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1. Gene 228: 1-12.
    • (1999) Gene , vol.228 , pp. 1-12
    • Stursberg, S.1    Riwar, B.2    Jessberger, R.3
  • 39
  • 40
    • 0035032649 scopus 로고    scopus 로고
    • Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation
    • Xu, B., Kim, S., and Kastan, M.B. 2001. Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation. Mol. Cell. Biol. 21: 3445-3450.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3445-3450
    • Xu, B.1    Kim, S.2    Kastan, M.B.3
  • 41
    • 0036146085 scopus 로고    scopus 로고
    • Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
    • Xu, B., Kim, S.T., Lim, D.S., and Kastan, M.B. 2002. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol. Cell. Biol. 22: 1049-1059.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1049-1059
    • Xu, B.1    Kim, S.T.2    Lim, D.S.3    Kastan, M.B.4
  • 42
    • 0036500690 scopus 로고    scopus 로고
    • SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
    • Yazdi, P.T., Wang, Y., Zhao, S., Patel, N., Lee, E.Y., and Qin, J. 2002. SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes & Dev. 16: 571-582.
    • (2002) Genes & Dev. , vol.16 , pp. 571-582
    • Yazdi, P.T.1    Wang, Y.2    Zhao, S.3    Patel, N.4    Lee, E.Y.5    Qin, J.6
  • 43
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.