Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

Molecular and Cellular Biology

Volumn 22, Issue 18, 2002, Pages 6521-6532

  Hirao, Atsushi ^a   Cheung, Alison ^a   Duncan, Gordon ^a   Girard, Pierre Marie ^a   Elia, Andrew J ^a   Wakeham, Andrew ^a   Okada, Hitoshi ^a   Sarkissian, Talin ^a   Wong, Jorge A ^a   Sakai, Takashi ^a   De Stanchina, Elisa ^a   Bristow, Robert G ^a   Suda, Toshio ^a   Lowe, Scott W ^a   Jeggo, Penny A ^a   Elledge, Stephen J ^a   Mak, Tak W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ATM PROTEIN; CHECKPOINT KINASE 2; PROTEIN KINASE; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; FAMILIAL CANCER; GENE ACTIVATION; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SKIN TUMOR; THYMOCYTE; TUMOR SUPPRESSOR GENE;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ALANINE; ANIMALS; APOPTOSIS; CARCINOGENS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GENES, P53; MALE; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NEOPLASMS, EXPERIMENTAL; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; THYMUS GLAND; TIME FACTORS; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0036724625     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.18.6521-6532.2002     Document Type: Article

References (56)

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