p53 heterozygosity alters the mRNA expression of p53 target genes in the bone marrow in response to inhaled benzene

Toxicological Sciences

Volumn 66, Issue 2, 2002, Pages 209-215

  Boley, Scott E ^a,c   Wong, Victoria A ^a   French, John E ^b   Recio, Leslie ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Altered expression; Benzene; DNA damage; Haploinsufficiency; Mouse; p53; Tumor

Indexed keywords

BENZENE; CYCLINE; DNA; GLUTAMATE DECARBOXYLASE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOASSAY; BONE MARROW; BONE MARROW CELL; CARCINOGENESIS; CARCINOGENICITY; CELL CYCLE; CONTROLLED STUDY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION; GENE LOCUS; GENE TARGETING; GENETIC REGULATION; GENOTOXICITY; HETEROZYGOSITY; HYPOTHESIS; INHALATION; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS;

ADMINISTRATION, INHALATION; AMINO ACID SEQUENCE; ANIMALS; BENZENE; BONE MARROW CELLS; GENE EXPRESSION REGULATION; GENES, P53; HETEROZYGOTE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0036211857     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/66.2.209     Document Type: Article

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