Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 3, 2007, Pages 649-653

  Sexton, Kelly B ^a   Witte, Martin D ^a,b   Blum, Galia ^a   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Activity based probes; Cysteine protease; Fluorescent labeling; Legumain

Indexed keywords

ASPARTIC ACID; CYSTEINE PROTEINASE; LEGUMAIN; PROTEOME;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL MEMBRANE PERMEABILITY; ENZYME SPECIFICITY; NONHUMAN;

CATHEPSIN B; CELL MEMBRANE PERMEABILITY; COMBINATORIAL CHEMISTRY TECHNIQUES; CYSTEINE ENDOPEPTIDASES; DRUG DESIGN; FLUORESCENT DYES; LYSOSOMES;

EID: 33846188177     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.10.100     Document Type: Article

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