Design and synthesis of AX7574: A microcystin-derived, fluorescent probe for serine/threonine phosphatases

Bioconjugate Chemistry

Volumn 15, Issue 4, 2004, Pages 790-798

  Shreder, Kevin R ^a   Liu, Yongsheng ^a   Nomanhboy, Tyzoon ^a   Fuller, Stacy R ^a   Wong, Melissa S ^a   Gai, Wen Zhi ^a   Wu, Jiangyue ^a   Leventhal, Phillip S ^a   Lill, Jennie R ^a   Corral, Sergio ^a  

^a ACTIVX BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASES; PROBES; TOXIC MATERIALS;

ACTIVE SITE; BASIC CONDITIONS; DIKETONE DERIVATIVES; FLUORESCENT PROBES; JURKAT CELL; MICROCYSTIN-LR; MICROCYSTINS; PHOSPHATASE ACTIVITY; PROTEIN PHOSPHATASE-1; SIDE-CHAINS;

AMINO ACIDS;

AX 7574; CYANOGINOSIN; CYANOGINOSIN LR; FLUORESCENT DYE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN PHOSPHATASE 4; PROTEIN PHOSPHATASE 6; PROTEIN SERINE THREONINE KINASE; RHODAMINE; SERINE THREONINE PHOSPHATASE; TETRAMETHYLRHODAMINE 1,3 DIKETONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONJUGATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; SENSITIVITY AND SPECIFICITY; STOICHIOMETRY;

EID: 3242759075     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0499580     Document Type: Article

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