Kinomics: Characterizing the therapeutically validated kinase space

Drug Discovery Today

Volumn 10, Issue 12, 2005, Pages 839-846

  Vieth, Michal ^a   Sutherland, Jeffrey J ^a   Robertson, Daniel H ^a   Campbell, Robert M ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BEVACIZUMAB; CEP 1347; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; EUPATILIN; FASUDIL; GEFITINIB; IMATINIB; LAPATINIB; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE; SORAFENIB; SU 1248; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR; VATALANIB;

AMINO ACID SEQUENCE; BINDING SITE; BRAIN HEMORRHAGE; CLINICAL TRIAL; DRUG APPROVAL; DRUG SELECTIVITY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME STRUCTURE; GASTRITIS; GENE TARGETING; GENOME ANALYSIS; GENOMICS; HUMAN; INHIBITION KINETICS; LIPOPHILICITY; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR WEIGHT; NONHUMAN; ONCOGENE; ONCOLOGY; PARKINSON DISEASE; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; STRUCTURE ANALYSIS; TREATMENT INDICATION; VALIDATION PROCESS;

AMINO ACID SEQUENCE; BINDING SITES; DRUG DESIGN; HUMANS; MOLECULAR WEIGHT; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20444498116     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(05)03477-X     Document Type: Review

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