Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes.

Assay and drug development technologies

Volumn 1, Issue 1 Pt 2, 2003, Pages 137-146

  Nomanbhoy, Tyzoon K ^a   Rosenblum, Jonathan ^a   Aban, Arwin ^a   Burbaum, Jonathan J ^a  

^a ACTIVX BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; DRUG; DRUG DERIVATIVE; FLUORESCENT DYE; ISOLEUCINE; ISOLEUCYL THIAZOLIDIDE; ISOLEUCYL-THIAZOLIDIDE; MEMBRANE PROTEIN; PHOSPHONIC ACID DERIVATIVE; PROTEIN; PROTEINASE INHIBITOR; PROTEOME; THIAZOLE DERIVATIVE;

ANIMAL; ARTICLE; BINDING COMPETITION; BINDING SITE; CELL CULTURE; CELL LINE; CHEMISTRY; DRUG DESIGN; HUMAN; IN VITRO STUDY; KIDNEY; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIGENS, CD26; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CELLS, CULTURED; DRUG DESIGN; FLUORESCENT DYES; HUMANS; ISOLEUCINE; KIDNEY; MEMBRANE PROTEINS; MICE; PHARMACEUTICAL PREPARATIONS; PHOSPHONIC ACIDS; PROTEASE INHIBITORS; PROTEINS; PROTEOME; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

MLCS; MLOWN;

EID: 3242716915     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/154065803762851306     Document Type: Article

References (0)