Synthesis and characterization of 5′-p-fluorosulfonylbenzoyl-2′ (or 3′]-(biotinyl)adenosine as an activity-based probe for protein kinases

Journal of Biomolecular Screening

Volumn 12, Issue 1, 2007, Pages 126-132

  Ratcliffe, Steven J ^a   Yi, Tracey ^b   Khandekar, Sanjay S ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Activity based probes; ATP binding site; Biotinyl FSBA; Kinase inhibitors; LC MS; Western blot

Indexed keywords

5',4 FLUOROSULFONYLBENZOYL 2' BIOTINYLADENOSINE; 5',4 FLUOROSULFONYLBENZOYL 3' BIOTINYLADENOSINE; ADENOSINE TRIPHOSPHATE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SYNTHESIS; MOLECULAR PROBE; PRIORITY JOURNAL; SCREENING; WESTERN BLOTTING;

ADENOSINE; ADENOSINE TRIPHOSPHATE; BINDING, COMPETITIVE; BIOTIN; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; MASS SPECTROMETRY; MOLECULAR PROBES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES;

EID: 33846856907     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106296685     Document Type: Article

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