Engineering synthetic vectors for improved DNA delivery: Insights from intracellular pathways

Annual Review of Biomedical Engineering

Volumn 6, Issue , 2004, Pages 397-426

  Roth, Charles M ^a,b   Sundaram, Sumati ^a  

^a The State University of New Jersey   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Antisense oligonucleotides; Intracellular trafficking; Nonviral gene delivery; Rational design; Targeted delivery

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ASIALOGLYCOPROTEIN; CHITOSAN; DRUG CARRIER; FOLIC ACID; LIPID; LIPOSOME; N (2 HYDROXYPROPYL)METHACRYLAMIDE; PLASMID VECTOR; POLYETHYLENEIMINE; POLYLYSINE; RETROVIRUS VECTOR; REV PROTEIN; TRANSACTIVATOR PROTEIN;

BIOENGINEERING; CARCINOGENESIS; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; DNA METHYLATION; DNA PACKAGING; DNA VECTOR; ENDOCYTOSIS; GENE EXPRESSION; GENE TARGETING; GENE TECHNOLOGY; GENE THERAPY; HOST CELL; HUMAN; HYDROPHOBICITY; IMMUNOGENICITY; INTERNALIZATION; MATHEMATICAL MODEL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REVIEW; STRUCTURE ACTIVITY RELATION; TARGET CELL; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BIOLOGICAL TRANSPORT; DNA; ENDOCYTOSIS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; OLIGONUCLEOTIDES, ANTISENSE; VIRUSES;

UNIDENTIFIED RETROVIRUS;

EID: 4444370741     PISSN: 15239829     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.bioeng.6.040803.140203     Document Type: Review

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