Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design

Biotechnology and Bioengineering

Volumn 70, Issue 6, 2000, Pages 593-605

  Varga, Csanad M ^a   Wickham, Thomas J ^c   Lauffenburger, Douglas A ^a,b,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c GENVEC INC   (United States)

Author keywords

Cell engineering; Gene delivery; Gene therapy; Receptor targeting; Receptor ligand dynamics; Synthetic vectors; Vectors; Viral vectors

Indexed keywords

ANTIBODY; ASIALOGLYCOPROTEIN; DNA; EPIDERMAL GROWTH FACTOR; ERYTHROPOIETIN; FIBROBLAST GROWTH FACTOR; FOLIC ACID; GLYCOSIDE; HEPARIN; NEU DIFFERENTIATION FACTOR; NUCLEIC ACID; RECEPTOR; STEEL FACTOR; TRANSFERRIN; VIRUS VECTOR;

ENDOCYTOSIS; ENGINEERING; GENE; GENE TARGETING; GENE THERAPY; HUMAN; NONHUMAN; REVIEW;

ANIMALS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; TRANSGENES; VIRUSES;

EID: 0034694930     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20001220)70:6<593::AID-BIT1>3.0.CO;2-N     Document Type: Review

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