-
1
-
-
0028875936
-
Transfer of genes to humans: Early lessons and obstacles to success
-
Crystal RG: Transfer of genes to humans: early lessons and obstacles to success. Science 270:404, 1995
-
(1995)
Science
, vol.270
, pp. 404
-
-
Crystal, R.G.1
-
2
-
-
0030928619
-
Gene therapy - Promises, problems and prospects
-
Verma IM, Somia N: Gene therapy - Promises, problems and prospects [news]. Nature 389:239, 1997
-
(1997)
Nature
, vol.389
, pp. 239
-
-
Verma, I.M.1
Somia, N.2
-
3
-
-
0017670013
-
Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
-
Paterson BM, Roberts BE, Kuff EL: Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc Natl Acad Sci USA 74:4370, 1977
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 4370
-
-
Paterson, B.M.1
Roberts, B.E.2
Kuff, E.L.3
-
4
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik PC, Stephenson ML: Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA 75:280, 1978
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 280
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
5
-
-
0020826922
-
Translational control of IS10 transposition
-
Simons RW, Kleckner N: Translational control of IS10 transposition. Cell 34:683, 1983
-
(1983)
Cell
, vol.34
, pp. 683
-
-
Simons, R.W.1
Kleckner, N.2
-
6
-
-
0344363037
-
A unique mechanism regulating gene expression: Translational inhibition by a complementary RNA transcript (micRNA)
-
Mizuno T, Chou MY, Inouye M: A unique mechanism regulating gene expression: Translational inhibition by a complementary RNA transcript (micRNA). Proc Natl Acad Sci USA 81:1966, 1984
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 1966
-
-
Mizuno, T.1
Chou, M.Y.2
Inouye, M.3
-
7
-
-
0021229867
-
Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis
-
Izant JG, Weintraub H: Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis. Cell 36:1007, 1984
-
(1984)
Cell
, vol.36
, pp. 1007
-
-
Izant, J.G.1
Weintraub, H.2
-
8
-
-
0028135079
-
Altering mice by homologous recombination using embryonic stem cells
-
Bronson SK, Smithies O: Altering mice by homologous recombination using embryonic stem cells. J Biol Chem 269:27155, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 27155
-
-
Bronson, S.K.1
Smithies, O.2
-
9
-
-
0027243084
-
Parallel DNA triplexes, homologous recombination, and other homology-dependent DNA interactions
-
Camerini-Otero RD, Hsieh P: Parallel DNA triplexes, homologous recombination, and other homology-dependent DNA interactions. Cell 73:217, 1993
-
(1993)
Cell
, vol.73
, pp. 217
-
-
Camerini-Otero, R.D.1
Hsieh, P.2
-
10
-
-
0029989219
-
Recent advances in gene mutagenesis by site-directed recombination
-
Marth JD: Recent advances in gene mutagenesis by site-directed recombination. J Clin Invest 97:1999, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 1999
-
-
Marth, J.D.1
-
11
-
-
0029051295
-
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development
-
Shivdasani RA, Rosenblatt MR Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH: Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell 81:695, 1995
-
(1995)
Cell
, vol.81
, pp. 695
-
-
Shivdasani, R.A.1
Rosenblatt, M.R.2
Zucker-Franklin, D.3
Jackson, C.W.4
Hunt, P.5
Saris, C.J.6
Orkin, S.H.7
-
12
-
-
0030049003
-
A functional analysis of protooncogene Vav's role in adult human hematopoiesis
-
Luger SM, Ratajczak J, Ratajczak MZ, Kuczynski WI, DiPaola RS, Ngo W, Clevenger CV, Gewirtz AM: A functional analysis of protooncogene Vav's role in adult human hematopoiesis. Blood 87:1326, 1996
-
(1996)
Blood
, vol.87
, pp. 1326
-
-
Luger, S.M.1
Ratajczak, J.2
Ratajczak, M.Z.3
Kuczynski, W.I.4
DiPaola, R.S.5
Ngo, W.6
Clevenger, C.V.7
Gewirtz, A.M.8
-
13
-
-
0030075797
-
Triplex-mediated, in vitro targeting of psoralen photoadducts within the genome of a transgenic mouse
-
Gunther EJ, Havre PA, Gasparro FP, Glazer PM: Triplex-mediated, in vitro targeting of psoralen photoadducts within the genome of a transgenic mouse. Photochem Photobiol 63:207, 1996
-
(1996)
Photochem Photobiol
, vol.63
, pp. 207
-
-
Gunther, E.J.1
Havre, P.A.2
Gasparro, F.P.3
Glazer, P.M.4
-
14
-
-
0029873110
-
Prospects for the therapeutic use of antigene oligonucleotides
-
Maher L Jr: Prospects for the therapeutic use of antigene oligonucleotides. Cancer Invest 14:66, 1996
-
(1996)
Cancer Invest
, vol.14
, pp. 66
-
-
Maher Jr., L.1
-
15
-
-
0029866449
-
Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: High frequency and altered spectrum in a xeroderma pigmentosum variant
-
Raha M, Wang G, Seidman MM, Glazer PM: Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant. Proc Natl Acad Sci USA 93:2941, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2941
-
-
Raha, M.1
Wang, G.2
Seidman, M.M.3
Glazer, P.M.4
-
16
-
-
0029915739
-
Sequence-specific arrest of primer extension on single-stranded DNA by an oligonucleotide-minor groove binder conjugate
-
Afonina I, Kutyavin I, Lukhtanov E, Meyer RB, Gamper H: Sequence-specific arrest of primer extension on single-stranded DNA by an oligonucleotide-minor groove binder conjugate. Proc Natl Acad Sci USA 93:3199, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3199
-
-
Afonina, I.1
Kutyavin, I.2
Lukhtanov, E.3
Meyer, R.B.4
Gamper, H.5
-
17
-
-
0028348628
-
Effect of 5-methylcytosine on the structure and stability of DNA. Formation of triple-stranded concatenamers by overlapping oligonucleotides
-
Xodo LE, Alunni-Fabbroni M, Manzini G: Effect of 5-methylcytosine on the structure and stability of DNA. Formation of triple-stranded concatenamers by overlapping oligonucleotides. J Biomol Struct Dyn 11:703, 1994
-
(1994)
J Biomol Struct Dyn
, vol.11
, pp. 703
-
-
Xodo, L.E.1
Alunni-Fabbroni, M.2
Manzini, G.3
-
18
-
-
0029756766
-
Effect of third strand composition on the triple helix formation: Purine versus pyrimidine oligodeoxynucleotides
-
Faucon B, Mergny JL, Helene C: Effect of third strand composition on the triple helix formation: purine versus pyrimidine oligodeoxynucleotides. Nucleic Acids Res 24:3181, 1996
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 3181
-
-
Faucon, B.1
Mergny, J.L.2
Helene, C.3
-
19
-
-
1842333857
-
Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine
-
Faruqi AF, Krawczyk SH, Matteucci MD, Glazer PM: Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine. Nucleic Acids Res 25:633, 1997
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 633
-
-
Faruqi, A.F.1
Krawczyk, S.H.2
Matteucci, M.D.3
Glazer, P.M.4
-
20
-
-
0028095434
-
A short purine oligonucleotide forms a highly stable triple helix with the promoter of the murine c-pim-1 proto-oncogene
-
Svinarchuk F, Bertrand JR, Malvy C: A short purine oligonucleotide forms a highly stable triple helix with the promoter of the murine c-pim-1 proto-oncogene. Nucleic Acids Res 22:3742, 1994
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3742
-
-
Svinarchuk, F.1
Bertrand, J.R.2
Malvy, C.3
-
21
-
-
0027986871
-
Efficient unwinding of triplex DNA by a DNA helicase
-
Maine IP, Kodadek T: Efficient unwinding of triplex DNA by a DNA helicase. Biochem Biophys Res Commun 204:1119, 1994
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1119
-
-
Maine, I.P.1
Kodadek, T.2
-
22
-
-
0029965966
-
Alternate strand recognition of double-helical DNA by (T,G)-containing oligonucleotides in the presence of a triple helix-specific ligand
-
de Bizemont T, Duval-Valentin G, Sun JS, Bisagni E, Garestier T, Helene C: Alternate strand recognition of double-helical DNA by (T,G)-containing oligonucleotides in the presence of a triple helix-specific ligand. Nucleic Acids Res 24:1136, 1996
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1136
-
-
De Bizemont, T.1
Duval-Valentin, G.2
Sun, J.S.3
Bisagni, E.4
Garestier, T.5
Helene, C.6
-
23
-
-
0028085526
-
Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides
-
Washbrook E, Fox KR: Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides. Biochem J 301:569, 1994
-
(1994)
Biochem J
, vol.301
, pp. 569
-
-
Washbrook, E.1
Fox, K.R.2
-
24
-
-
1842378588
-
Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative
-
Lacoste J, Francois JC, Helene C: Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative. Nucleic Acids Res 25:1991, 1997
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1991
-
-
Lacoste, J.1
Francois, J.C.2
Helene, C.3
-
25
-
-
0029623151
-
Specific cleavage of a DNA triple helix by FeII.bleomycin
-
Kane SA, Hecht SM, Sun JS, Garestier T, Helene C: Specific cleavage of a DNA triple helix by FeII.bleomycin. Biochemistry 34:16715, 1995
-
(1995)
Biochemistry
, vol.34
, pp. 16715
-
-
Kane, S.A.1
Hecht, S.M.2
Sun, J.S.3
Garestier, T.4
Helene, C.5
-
26
-
-
0028111610
-
Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: Characterization of psoralen monoadduct and crosslink formation
-
Gasparro FP, Havre PA, Olack GA, Gunther EJ, Glazer PM: Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: characterization of psoralen monoadduct and crosslink formation. Nucleic Acids Res 22:2845, 1994
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2845
-
-
Gasparro, F.P.1
Havre, P.A.2
Olack, G.A.3
Gunther, E.J.4
Glazer, P.M.5
-
27
-
-
0029778392
-
Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation
-
Grant KB, Dervan PB: Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation. Biochemistry 35:12313, 1996
-
(1996)
Biochemistry
, vol.35
, pp. 12313
-
-
Grant, K.B.1
Dervan, P.B.2
-
28
-
-
0030059301
-
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair
-
Wang G, Seidman MM, Glazer PM: Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. Science 271:802, 1996
-
(1996)
Science
, vol.271
, pp. 802
-
-
Wang, G.1
Seidman, M.M.2
Glazer, P.M.3
-
29
-
-
0029895972
-
DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells
-
Kochetkova M, Shannon MF: DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells. J Biol Chem 271:14438, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 14438
-
-
Kochetkova, M.1
Shannon, M.F.2
-
30
-
-
0030925139
-
Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells
-
Kochetkova M, Iversen PO, Lopez AF, Shannon MF: Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells. J Clin Invest 99:3000, 1997
-
(1997)
J Clin Invest
, vol.99
, pp. 3000
-
-
Kochetkova, M.1
Iversen, P.O.2
Lopez, A.F.3
Shannon, M.F.4
-
31
-
-
0029918243
-
Genomic targeting and genetic conversion in cancer therapy
-
Kmiec EB: Genomic targeting and genetic conversion in cancer therapy. Semin Oncol 23:188, 1996
-
(1996)
Semin Oncol
, vol.23
, pp. 188
-
-
Kmiec, E.B.1
-
32
-
-
0028859271
-
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation
-
Wang G, Levy DD, Seidman MM, Glazer PM: Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. Mol Cell Biol 15:1759, 1995
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1759
-
-
Wang, G.1
Levy, D.D.2
Seidman, M.M.3
Glazer, P.M.4
-
33
-
-
0031953132
-
In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides
-
Kren BT, Bandyopadhyay P, Steer CJ: In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides [see comments]. Nat Med 4:285, 1998
-
(1998)
Nat Med
, vol.4
, pp. 285
-
-
Kren, B.T.1
Bandyopadhyay, P.2
Steer, C.J.3
-
34
-
-
0029031549
-
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo
-
Morishita R, Gibbons GH, Horiuchi M, Ellison KE, Nakama M, Zhang L, Kaneda Y, Ogihara T, Dzau VJ: A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci USA 92:5855, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5855
-
-
Morishita, R.1
Gibbons, G.H.2
Horiuchi, M.3
Ellison, K.E.4
Nakama, M.5
Zhang, L.6
Kaneda, Y.7
Ogihara, T.8
Dzau, V.J.9
-
35
-
-
0029980617
-
Transcription factor decoy approach to decipher the role of NF-kappa B in oncogenesis
-
Sharma HW, Perez JR, Higgins-Sochaski K, Hsiao R, Narayanan R: Transcription factor decoy approach to decipher the role of NF-kappa B in oncogenesis. Anticancer Res 16:61, 1996
-
(1996)
Anticancer Res
, vol.16
, pp. 61
-
-
Sharma, H.W.1
Perez, J.R.2
Higgins-Sochaski, K.3
Hsiao, R.4
Narayanan, R.5
-
37
-
-
0022993284
-
Destabilization of messenger RNA/ complementary DNA duplexes by the elongating 80 S ribosome
-
Shakin SH, Liebhaber SA: Destabilization of messenger RNA/ complementary DNA duplexes by the elongating 80 S ribosome. J Biol Chem 261:16018, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 16018
-
-
Shakin, S.H.1
Liebhaber, S.A.2
-
38
-
-
0025262223
-
Kinetic analysis of Escherichia coli RNase H using DNA-RNA-DNA/DNA substrates
-
Hogrefe HH, Hogrefe RI, Walder RY, Walder JA: Kinetic analysis of Escherichia coli RNase H using DNA-RNA-DNA/DNA substrates. J Biol Chem 265:5561, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 5561
-
-
Hogrefe, H.H.1
Hogrefe, R.I.2
Walder, R.Y.3
Walder, J.A.4
-
39
-
-
0026175462
-
Substrate specificity and kinetics of degradation of antisense oligonucleotides by a 3′ exonuclease in plasma
-
Eder PS, DeVine RJ, Dagle JM, Walder JA: Substrate specificity and kinetics of degradation of antisense oligonucleotides by a 3′ exonuclease in plasma. Antisense Res Dev 1:141, 1991
-
(1991)
Antisense Res Dev
, vol.1
, pp. 141
-
-
Eder, P.S.1
DeVine, R.J.2
Dagle, J.M.3
Walder, J.A.4
-
40
-
-
0025015229
-
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides
-
Agrawal S, Mayrand SH, Zamecnik PC, Pederson T: Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci USA 87:1401, 1990
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1401
-
-
Agrawal, S.1
Mayrand, S.H.2
Zamecnik, P.C.3
Pederson, T.4
-
42
-
-
0026115923
-
Pathways of degradation and mechanism of action of antisense oligonucleotides in Xenopus laevis embryos
-
Dagle JM, Weeks DL, Walder JA: Pathways of degradation and mechanism of action of antisense oligonucleotides in Xenopus laevis embryos. Antisense Res Dev 1:11, 1991
-
(1991)
Antisense Res Dev
, vol.1
, pp. 11
-
-
Dagle, J.M.1
Weeks, D.L.2
Walder, J.A.3
-
43
-
-
0027191383
-
Effect of over-expression of bacterial ribonuclease H on the utility of antisense MYC oligodeoxynucleotides in the monocytic leukemia cell line U937
-
Rosolen A, Kyle E, Chavany C, Bergan R, Kalman ET, Crouch R, Neckers L: Effect of over-expression of bacterial ribonuclease H on the utility of antisense MYC oligodeoxynucleotides in the monocytic leukemia cell line U937. Biochimie 75:797, 1993
-
(1993)
Biochimie
, vol.75
, pp. 797
-
-
Rosolen, A.1
Kyle, E.2
Chavany, C.3
Bergan, R.4
Kalman, E.T.5
Crouch, R.6
Neckers, L.7
-
44
-
-
0028968912
-
Site and mechanism of antisense inhibition by C-5 propyne oligonucleotides
-
Moulds C, Lewis JG, Froehler BC, Grant D, Huang T, Milligan JF, Matteucci MD, Wagner RW: Site and mechanism of antisense inhibition by C-5 propyne oligonucleotides. Biochemistry 34:5044, 1995
-
(1995)
Biochemistry
, vol.34
, pp. 5044
-
-
Moulds, C.1
Lewis, J.G.2
Froehler, B.C.3
Grant, D.4
Huang, T.5
Milligan, J.F.6
Matteucci, M.D.7
Wagner, R.W.8
-
45
-
-
0028949890
-
Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells
-
Giles RV, Ruddell CJ, Spiller DG, Green JA, Tidd DM: Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells. Nucleic Acids Res 23:954, 1995
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 954
-
-
Giles, R.V.1
Ruddell, C.J.2
Spiller, D.G.3
Green, J.A.4
Tidd, D.M.5
-
46
-
-
0029016580
-
Optimization of antisense oligodeoxynucleotide structure for targeting bcr-abl mRNA
-
Giles RV, Spiller DG, Green JA, Clark RE, Tidd DM: Optimization of antisense oligodeoxynucleotide structure for targeting bcr-abl mRNA. Blood 86:744, 1995
-
(1995)
Blood
, vol.86
, pp. 744
-
-
Giles, R.V.1
Spiller, D.G.2
Green, J.A.3
Clark, R.E.4
Tidd, D.M.5
-
47
-
-
0027651958
-
Double-stranded RNA adenosine deaminase as a potential mammalian RNA editing factor
-
Kim U, Nishikura K: Double-stranded RNA adenosine deaminase as a potential mammalian RNA editing factor. Semin Cell Biol 4:285, 1993
-
(1993)
Semin Cell Biol
, vol.4
, pp. 285
-
-
Kim, U.1
Nishikura, K.2
-
48
-
-
0027972952
-
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing
-
Kim U, Wang Y, Sanford T, Zeng Y, Nishikura K: Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc Natl Acad Sci USA 91:11457, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11457
-
-
Kim, U.1
Wang, Y.2
Sanford, T.3
Zeng, Y.4
Nishikura, K.5
-
49
-
-
0028360566
-
Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts
-
Kim U, Garner TL, Sanford T, Speicher D, Murray JM, Nishikura K: Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts. J Biol Chem 269:13480, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 13480
-
-
Kim, U.1
Garner, T.L.2
Sanford, T.3
Speicher, D.4
Murray, J.M.5
Nishikura, K.6
-
50
-
-
0027756744
-
The efficiency and versatility of catalytic RNA: Implications for an RNA world
-
Cech TR: The efficiency and versatility of catalytic RNA: implications for an RNA world. Gene 135:33, 1993
-
(1993)
Gene
, vol.135
, pp. 33
-
-
Cech, T.R.1
-
51
-
-
0027190905
-
Catalytic RNA: Structure and mechanism
-
Cech TR: Catalytic RNA: structure and mechanism. Biochem Soc Trans 21:229, 1993
-
(1993)
Biochem Soc Trans
, vol.21
, pp. 229
-
-
Cech, T.R.1
-
52
-
-
0027183545
-
Ribozymes: A distinct class of metalloenzymes
-
Pyle AM: Ribozymes: A distinct class of metalloenzymes [see comments]. Science 261:709, 1993
-
(1993)
Science
, vol.261
, pp. 709
-
-
Pyle, A.M.1
-
53
-
-
0031973036
-
The therapeutic potential of ribozymes
-
James HA, Gibson I: The therapeutic potential of ribozymes. Blood 91:371, 1998
-
(1998)
Blood
, vol.91
, pp. 371
-
-
James, H.A.1
Gibson, I.2
-
54
-
-
0024435363
-
Studies on the hammerhead RNA self-cleaving domain
-
Ruffner D, Dahm S, Uhlenbeck O: Studies on the hammerhead RNA self-cleaving domain. Gene 82:31, 1989
-
(1989)
Gene
, vol.82
, pp. 31
-
-
Ruffner, D.1
Dahm, S.2
Uhlenbeck, O.3
-
55
-
-
0026515135
-
Ribozymes which cleave arenavirus RNAs: Identification of susceptible target sites and inhibition by target site secondary structure
-
Xing Z, Whitton JL: Ribozymes which cleave arenavirus RNAs: Identification of susceptible target sites and inhibition by target site secondary structure. J Virol 66:1361, 1992
-
(1992)
J Virol
, vol.66
, pp. 1361
-
-
Xing, Z.1
Whitton, J.L.2
-
56
-
-
0028472621
-
Inventing and improving ribozyme function: Rational design versus iterative selection methods
-
Breaker RR, Joyce GF: Inventing and improving ribozyme function: rational design versus iterative selection methods. Trends Biotechnol 12:268, 1994
-
(1994)
Trends Biotechnol
, vol.12
, pp. 268
-
-
Breaker, R.R.1
Joyce, G.F.2
-
58
-
-
0031114113
-
Ribozymes. Their functions and strategies for their use
-
Gibson SA, Shillitoe EJ: Ribozymes. Their functions and strategies for their use. Mol Biotechnol 7:125, 1997
-
(1997)
Mol Biotechnol
, vol.7
, pp. 125
-
-
Gibson, S.A.1
Shillitoe, E.J.2
-
59
-
-
0030996755
-
The new world of ribozymes
-
Jaeger L: The new world of ribozymes. Curr Opin Struct Biol 7:324, 1997
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 324
-
-
Jaeger, L.1
-
60
-
-
0027328396
-
Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1
-
Homann M, Tzortzakaki S, Rittner K, Sczakiel G, Tabler M: Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1. Nucleic Acids Res 21:2809, 1993
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2809
-
-
Homann, M.1
Tzortzakaki, S.2
Rittner, K.3
Sczakiel, G.4
Tabler, M.5
-
62
-
-
0030813878
-
The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells
-
Hormes R, Homann M, Oelze I, Marschall P, Tabler M, Eckstein F, Sczakiel G: The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells. Nucleic Acids Res 25:769, 1997
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 769
-
-
Hormes, R.1
Homann, M.2
Oelze, I.3
Marschall, P.4
Tabler, M.5
Eckstein, F.6
Sczakiel, G.7
-
63
-
-
10544234615
-
Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb
-
Jarvis TC, Wincott FE, Alby LJ, McSwiggen JA, Beigelman L, Gustofson J, DiRenzo A, Levy K, Arthur M, Matulic-Adamic J, Karpeisky A, Gonzalez C, Woolf TM, Usman N, Stinchcomb DT: Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb. J Biol Chem 271:29107, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 29107
-
-
Jarvis, T.C.1
Wincott, F.E.2
Alby, L.J.3
McSwiggen, J.A.4
Beigelman, L.5
Gustofson, J.6
DiRenzo, A.7
Levy, K.8
Arthur, M.9
Matulic-Adamic, J.10
Karpeisky, A.11
Gonzalez, C.12
Woolf, T.M.13
Usman, N.14
Stinchcomb, D.T.15
-
64
-
-
0029160633
-
Structure-function relationships of hammerhead ribozymes: From understanding to applications
-
Sigurdsson ST, Eckstein F: Structure-function relationships of hammerhead ribozymes: From understanding to applications. Trends Biotechnol 13:286, 1995
-
(1995)
Trends Biotechnol
, vol.13
, pp. 286
-
-
Sigurdsson, S.T.1
Eckstein, F.2
-
65
-
-
0027238265
-
In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1
-
Rittner K, Burmester C, Sczakiel G: In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1. Nucleic Acids Res 21:1381, 1993
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 1381
-
-
Rittner, K.1
Burmester, C.2
Sczakiel, G.3
-
66
-
-
0030750183
-
Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction
-
McConnell TS, Herschlag D, Cech TR: Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction. Biochemistry 36:8293, 1997
-
(1997)
Biochemistry
, vol.36
, pp. 8293
-
-
McConnell, T.S.1
Herschlag, D.2
Cech, T.R.3
-
67
-
-
0031472671
-
Hammerhead ribozyme activity in the presence of low molecular weight cellular extract
-
Nedbal W, Sczakiel G: Hammerhead ribozyme activity in the presence of low molecular weight cellular extract. Antisense Nucleic Acid Drug Dev 7:585, 1997
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 585
-
-
Nedbal, W.1
Sczakiel, G.2
-
68
-
-
0025085590
-
Catalysis of RNA cleavage by the tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site
-
Herschlag D, Cech T: Catalysis of RNA cleavage by the tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochemistry 29:10159, 1990
-
(1990)
Biochemistry
, vol.29
, pp. 10159
-
-
Herschlag, D.1
Cech, T.2
-
69
-
-
0027742736
-
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA
-
Sullenger BA, Cech TR: Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. Science 262:1566, 1993
-
(1993)
Science
, vol.262
, pp. 1566
-
-
Sullenger, B.A.1
Cech, T.R.2
-
70
-
-
12644252947
-
The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization
-
Bertrand E, Castanotto D, Zhou C, Carbonnelle C, Lee NS, Good P, Chatterjee S, Grange T, Pictet R, Kohn D, Engelke D, Rossi JJ: The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization. RNA 3:75, 1997
-
(1997)
RNA
, vol.3
, pp. 75
-
-
Bertrand, E.1
Castanotto, D.2
Zhou, C.3
Carbonnelle, C.4
Lee, N.S.5
Good, P.6
Chatterjee, S.7
Grange, T.8
Pictet, R.9
Kohn, D.10
Engelke, D.11
Rossi, J.J.12
-
71
-
-
8044253998
-
Expression of small, therapeutic RNAs in human cell nuclei
-
Good PD, Krikos AJ, Li SX, Bertrand E, Lee NS, Giver L, Ellington A, Zaia JA, Rossi JJ, Engelke DR: Expression of small, therapeutic RNAs in human cell nuclei. Gene Ther 4:45, 1997
-
(1997)
Gene Ther
, vol.4
, pp. 45
-
-
Good, P.D.1
Krikos, A.J.2
Li, S.X.3
Bertrand, E.4
Lee, N.S.5
Giver, L.6
Ellington, A.7
Zaia, J.A.8
Rossi, J.J.9
Engelke, D.R.10
-
72
-
-
0030866432
-
Evaluating and enhancing ribozyme reaction efficiency in mammalian cells
-
Jones JT, Sullenger BA: Evaluating and enhancing ribozyme reaction efficiency in mammalian cells. Nat Biotechnol 15:902, 1997
-
(1997)
Nat Biotechnol
, vol.15
, pp. 902
-
-
Jones, J.T.1
Sullenger, B.A.2
-
73
-
-
0029348087
-
Probing RNA tertiary structure: Interhelical crosslinking of the hammerhead ribozyme
-
Sigurdsson ST, Tuschl T, Eckstein F: Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme, RNA 1:575, 1995
-
(1995)
RNA
, vol.1
, pp. 575
-
-
Sigurdsson, S.T.1
Tuschl, T.2
Eckstein, F.3
-
74
-
-
0030633027
-
Enhancement of ribozyme function by RNA binding proteins
-
Lee NS, Bertrand E, Rossi JJ: Enhancement of ribozyme function by RNA binding proteins. Methods Mol Biol 74:275, 1997
-
(1997)
Methods Mol Biol
, vol.74
, pp. 275
-
-
Lee, N.S.1
Bertrand, E.2
Rossi, J.J.3
-
75
-
-
0026521479
-
Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells
-
Lee TC, Sullenger BA, Gallardo HF, Ungers GE, Gilboa E: Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells. New Biol 4:66, 1992
-
(1992)
New Biol
, vol.4
, pp. 66
-
-
Lee, T.C.1
Sullenger, B.A.2
Gallardo, H.F.3
Ungers, G.E.4
Gilboa, E.5
-
76
-
-
0028593399
-
Reduction in replication of the human immunodeficiency virus type 1 in human T cell lines by polymerase III-driven transcription of chimeric tRNA-antisense RNA genes
-
Junker U, Rittner K, Homann M, Bevec D, Bohnlein E, Sczakiel G: Reduction in replication of the human immunodeficiency virus type 1 in human T cell lines by polymerase III-driven transcription of chimeric tRNA-antisense RNA genes. Antisense Res Dev4:165, 1994
-
(1994)
Antisense Res Dev
, vol.4
, pp. 165
-
-
Junker, U.1
Rittner, K.2
Homann, M.3
Bevec, D.4
Bohnlein, E.5
Sczakiel, G.6
-
77
-
-
0025837282
-
Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation
-
Sullenger BA, Gallardo HF, Ungers GE, Gilboa E: Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J Virol 65:6811, 1991
-
(1991)
J Virol
, vol.65
, pp. 6811
-
-
Sullenger, B.A.1
Gallardo, H.F.2
Ungers, G.E.3
Gilboa, E.4
-
78
-
-
85047673153
-
A novel method to stabilise antisense oligonucleotides against exonuclease degradation
-
[published erratum appears in Nucleic Acids Res 21:4433,1993]
-
Khan IM, Coulson JM: A novel method to stabilise antisense oligonucleotides against exonuclease degradation [published erratum appears in Nucleic Acids Res 21:4433,1993]. Nucleic Acids Res 21:2957, 1993
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2957
-
-
Khan, I.M.1
Coulson, J.M.2
-
79
-
-
0029943016
-
Potent and selective inhibition of gene expression by an antisense heptanucleotide
-
Wagner RW, Matteucci MD, Grant D, Huang T, Froehler BC: Potent and selective inhibition of gene expression by an antisense heptanucleotide. Nature Biotechnol 14:840, 1996
-
(1996)
Nature Biotechnol
, vol.14
, pp. 840
-
-
Wagner, R.W.1
Matteucci, M.D.2
Grant, D.3
Huang, T.4
Froehler, B.C.5
-
80
-
-
0028244690
-
Noninvasive imaging of c-myc oncogene messenger RNA with indium-111 -antisense probes in a mammary tumor-bearing mouse model
-
Dewanjee MK, Ghafouripour AK, Kapadvanjwala M, Dewanjee S, Serafini AN, Lopez DM, Sfakianakis GN: Noninvasive imaging of c-myc oncogene messenger RNA with indium-111 -antisense probes in a mammary tumor-bearing mouse model [see comments]. J Nucl Med 35:1054, 1994
-
(1994)
J Nucl Med
, vol.35
, pp. 1054
-
-
Dewanjee, M.K.1
Ghafouripour, A.K.2
Kapadvanjwala, M.3
Dewanjee, S.4
Serafini, A.N.5
Lopez, D.M.6
Sfakianakis, G.N.7
-
81
-
-
0030004872
-
Facilitating oligonucleotide delivery: Helping antisense deliver on its promise
-
Gewirtz AM, Stein CA, Glazer PM: Facilitating oligonucleotide delivery: helping antisense deliver on its promise. Proc Natl Acad Sci USA 93:3161, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3161
-
-
Gewirtz, A.M.1
Stein, C.A.2
Glazer, P.M.3
-
83
-
-
0030623524
-
Advances in understanding the pharmacological properties of antisense oligonucleotides
-
Crooke ST: Advances in understanding the pharmacological properties of antisense oligonucleotides. Adv Pharmacol 40:1, 1997
-
(1997)
Adv Pharmacol
, vol.40
, pp. 1
-
-
Crooke, S.T.1
-
84
-
-
0026754351
-
Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides
-
Ratajczak MZ, Hijiya N, Catani L, DeRiel K, Luger SM, McGlave P, Gewirtz AM: Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides. Blood 79:1956, 1992
-
(1992)
Blood
, vol.79
, pp. 1956
-
-
Ratajczak, M.Z.1
Hijiya, N.2
Catani, L.3
DeRiel, K.4
Luger, S.M.5
McGlave, P.6
Gewirtz, A.M.7
-
85
-
-
0026512323
-
Role of the KIT protooncogene in normal and malignant human hematopoiesis
-
Ratajczak MZ, Luger SM, DeRiel K, Abrahm J, Calabretta B, Gewirtz AM: Role of the KIT protooncogene in normal and malignant human hematopoiesis. Proc Natl Acad Sci USA 89:1710, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1710
-
-
Ratajczak, M.Z.1
Luger, S.M.2
DeRiel, K.3
Abrahm, J.4
Calabretta, B.5
Gewirtz, A.M.6
-
86
-
-
0027955112
-
STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells
-
Small D, Levenstein M, Kim E, Carow C, Amin S, Rockwell P, Witte L, Burrow C, Ratajczak MZ, Gewirtz AM, Civin C: STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc Natl Acad Sci USA 91:459, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 459
-
-
Small, D.1
Levenstein, M.2
Kim, E.3
Carow, C.4
Amin, S.5
Rockwell, P.6
Witte, L.7
Burrow, C.8
Ratajczak, M.Z.9
Gewirtz, A.M.10
Civin, C.11
-
87
-
-
0028321751
-
A reappraisal of the role of insulin-like growth factor I in the regulation of human hematopoiesis
-
Ratajczak MZ, Kuczynski WI, Onodera K, Moore J, Ratajczak J, Kregenow DA, DeRiel K, Gewirtz AM: A reappraisal of the role of insulin-like growth factor I in the regulation of human hematopoiesis. J Clin Invest 94:320, 1994
-
(1994)
J Clin Invest
, vol.94
, pp. 320
-
-
Ratajczak, M.Z.1
Kuczynski, W.I.2
Onodera, K.3
Moore, J.4
Ratajczak, J.5
Kregenow, D.A.6
DeRiel, K.7
Gewirtz, A.M.8
-
88
-
-
0029134820
-
Expression and physiologic significance of Kit ligand and stem cell tyrosine kinase-1 receptor ligand in normal human CD34+, c-Kit+ marrow cells
-
Ratajczak MZ, Kuczynski WI, Sokol DL, Moore JS, Pletcher CH Jr, Gewirtz AM: Expression and physiologic significance of Kit ligand and stem cell tyrosine kinase-1 receptor ligand in normal human CD34+, c-Kit+ marrow cells. Blood 86:2161, 1995
-
(1995)
Blood
, vol.86
, pp. 2161
-
-
Ratajczak, M.Z.1
Kuczynski, W.I.2
Sokol, D.L.3
Moore, J.S.4
Pletcher Jr., C.H.5
Gewirtz, A.M.6
-
89
-
-
0029588560
-
Antisense phosphorothioate oligodeoxynucleotides: Introductory concepts and possible molecular mechanisms of toxicity
-
Zon G: Antisense phosphorothioate oligodeoxynucleotides: introductory concepts and possible molecular mechanisms of toxicity. Toxicol Lett 82-83:419, 1995
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 419
-
-
Zon, G.1
-
91
-
-
14744277298
-
Oligonucleoside methylphosphonates as antisense reagents
-
Miller PS: Oligonucleoside methylphosphonates as antisense reagents. Biotechnology (NY) 9:358, 1991
-
(1991)
Biotechnology (NY)
, vol.9
, pp. 358
-
-
Miller, P.S.1
-
92
-
-
0027416659
-
Chimeric oligodeoxynucleotide analogues: Enhanced cell uptake of structures which direct ribonuclease H with high specificity
-
Giles RV, Spiller DG, Tidd DM: Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity. Anticancer Drug Des 8:33, 1993
-
(1993)
Anticancer Drug Des
, vol.8
, pp. 33
-
-
Giles, R.V.1
Spiller, D.G.2
Tidd, D.M.3
-
93
-
-
0003236691
-
Oligodeoxynucleotide therapeutics for human myelogenous leukemia: Interim results
-
abstr, suppl1
-
Gewirtz AM, Luger S, Sokol D, Gowdin B, Stadtmauer E, Reccio A, Ratajczak MZ: Oligodeoxynucleotide therapeutics for human myelogenous leukemia: Interim results. Blood 88:270a, 1996 (abstr, suppl1)
-
(1996)
Blood
, vol.88
-
-
Gewirtz, A.M.1
Luger, S.2
Sokol, D.3
Gowdin, B.4
Stadtmauer, E.5
Reccio, A.6
Ratajczak, M.Z.7
-
94
-
-
0029144946
-
Antisense oligodeoxynucleotides for the treatment of chronic myelogenous leukemia: Are they still a promise?
-
de Fabritiis P, Calabretta B: Antisense oligodeoxynucleotides for the treatment of chronic myelogenous leukemia: Are they still a promise? [editorial]. Haematologica 80:295, 1995
-
(1995)
Haematologica
, vol.80
, pp. 295
-
-
De Fabritiis, P.1
Calabretta, B.2
-
95
-
-
0030888664
-
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
-
Webb A, Cunningham D, Cotter F, Clarke PA, di Stefano F, Ross P, Corbo M, Dziewanowska Z: BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 349:1137, 1997
-
(1997)
Lancet
, vol.349
, pp. 1137
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
Clarke, P.A.4
Di Stefano, F.5
Ross, P.6
Corbo, M.7
Dziewanowska, Z.8
-
96
-
-
0030943935
-
Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice
-
DeLong RK, Molting A, Fisher M, Chen Q, Wickstrom E, Kligshteyn M, Demirdji S, Caruthers M, Juliano RL: Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice. Antisense Nucleic Acid Drug Dev 7:71, 1997
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 71
-
-
DeLong, R.K.1
Molting, A.2
Fisher, M.3
Chen, Q.4
Wickstrom, E.5
Kligshteyn, M.6
Demirdji, S.7
Caruthers, M.8
Juliano, R.L.9
-
97
-
-
0028001098
-
Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides
-
Stein CA, Krieg AM: Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides [editorial]. Antisense Res Dev 4:67, 1994
-
(1994)
Antisense Res Dev
, vol.4
, pp. 67
-
-
Stein, C.A.1
Krieg, A.M.2
-
98
-
-
0028806487
-
Does antisense exist?
-
Stein CA: Does antisense exist? Nat Med 1:1119, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1119
-
-
Stein, C.A.1
-
99
-
-
0031426571
-
Antisense technology and prospects for therapy of viral infections and cancer
-
Wagner RW, Flanagan WM: Antisense technology and prospects for therapy of viral infections and cancer. Mol Med Today 3:31, 1997
-
(1997)
Mol Med Today
, vol.3
, pp. 31
-
-
Wagner, R.W.1
Flanagan, W.M.2
-
100
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
Guvakova MA, Yakubov LA, Vlodavsky I, Tonkinson JL, Stein CA: Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J Biol Chem 270:2620, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 2620
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
101
-
-
17144436717
-
Pharmacology and toxicology of phosphorothioate oligonucleotides in the mouse, rat, monkey and man
-
Iversen PL, Copple BL, Tewary HK: Pharmacology and toxicology of phosphorothioate oligonucleotides in the mouse, rat, monkey and man. Toxicol Lett 82-83:425, 1995
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 425
-
-
Iversen, P.L.1
Copple, B.L.2
Tewary, H.K.3
-
102
-
-
0031006756
-
Effects of synthetic oligonucleotides on human complement and coagulation
-
Shaw DR, Rustagi PK, Kandimalla ER, Manning AN, Jiang Z, Agrawal S: Effects of synthetic oligonucleotides on human complement and coagulation. Biochem Pharmacol 53:1123, 1997
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1123
-
-
Shaw, D.R.1
Rustagi, P.K.2
Kandimalla, E.R.3
Manning, A.N.4
Jiang, Z.5
Agrawal, S.6
-
103
-
-
0026573769
-
Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology
-
Gao WY, Han FS, Storm C, Egan W, Cheng YC: Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology. Mol Pharmacol 41:223, 1992
-
(1992)
Mol Pharmacol
, vol.41
, pp. 223
-
-
Gao, W.Y.1
Han, F.S.2
Storm, C.3
Egan, W.4
Cheng, Y.C.5
-
104
-
-
0028625387
-
Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats
-
Skutella T, Montkowski A, Stohr T, Probst JC, Landgraf R, Holsboer F, Jirikowski GF: Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats. Cell Mol Neurobiol 14:579, 1994
-
(1994)
Cell Mol Neurobiol
, vol.14
, pp. 579
-
-
Skutella, T.1
Montkowski, A.2
Stohr, T.3
Probst, J.C.4
Landgraf, R.5
Holsboer, F.6
Jirikowski, G.F.7
-
105
-
-
0026490041
-
Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity
-
Thierry AR, Dritschilo A: Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity. Nucleic Acids Res 20:5691, 1992
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 5691
-
-
Thierry, A.R.1
Dritschilo, A.2
-
106
-
-
0030909609
-
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
-
Agrawal S, Jiang Z, Zhao Q, Shaw D, Cai Q, Roskey A, Channavajjala L, Saxinger C, Zhang R: Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies. Proc Natl Acad Sci USA 94:2620, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2620
-
-
Agrawal, S.1
Jiang, Z.2
Zhao, Q.3
Shaw, D.4
Cai, Q.5
Roskey, A.6
Channavajjala, L.7
Saxinger, C.8
Zhang, R.9
-
107
-
-
0029156023
-
Synthesis of oligodeoxyribonucleotide N3′ → P5′ phosphoramidates
-
Chen JK, Schultz RG, Lloyd DH, Gryaznov SM: Synthesis of oligodeoxyribonucleotide N3′ → P5′ phosphoramidates. Nucleic Acids Res 23:2661, 1995
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2661
-
-
Chen, J.K.1
Schultz, R.G.2
Lloyd, D.H.3
Gryaznov, S.M.4
-
108
-
-
0029046548
-
Analysis of a ribonuclease H digestion of N3′ → P5′ phosphoramidate-RNA duplexes by capillary gel electrophoresis
-
DeDionisio L, Gryaznov SM: Analysis of a ribonuclease H digestion of N3′ → P5′ phosphoramidate-RNA duplexes by capillary gel electrophoresis. J Chromatogr B Biomed Appl 669:125, 1995
-
(1995)
J Chromatogr B Biomed Appl
, vol.669
, pp. 125
-
-
DeDionisio, L.1
Gryaznov, S.M.2
-
109
-
-
0029664865
-
Oligonucleotide N3′ → P5′ phosphoramidates as antisense agents
-
Gryaznov S, Skorski T, Cucco C, Nieborowska-Skorska M, Chiu CY, Lloyd D, Chen JK, Koziolkiewicz M, Calabretta B: Oligonucleotide N3′ → P5′ phosphoramidates as antisense agents. Nucleic Acids Res 24:1508, 1996
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1508
-
-
Gryaznov, S.1
Skorski, T.2
Cucco, C.3
Nieborowska-Skorska, M.4
Chiu, C.Y.5
Lloyd, D.6
Chen, J.K.7
Koziolkiewicz, M.8
Calabretta, B.9
-
110
-
-
0027474528
-
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents
-
Morvan F, Porumb H, Degols G, Lefebvre I, Pompon A, Sproat BS, Rayner B, Malvy C, Lebleu B, Imbach JL: Comparative evaluation of seven oligonucleotide analogues as potential antisense agents. J Med Chem 36:280, 1993
-
(1993)
J Med Chem
, vol.36
, pp. 280
-
-
Morvan, F.1
Porumb, H.2
Degols, G.3
Lefebvre, I.4
Pompon, A.5
Sproat, B.S.6
Rayner, B.7
Malvy, C.8
Lebleu, B.9
Imbach, J.L.10
-
111
-
-
0027018825
-
Inhibition of murine leukemia viruses by nuclease-resistant alpha-oligonucleotides
-
Lavignon M, Tounekti N, Rayner B, Imbach JL, Keith G, Paoletti J, Malvy C: Inhibition of murine leukemia viruses by nuclease-resistant alpha-oligonucleotides. Antisense Res Dev 2:315, 1992
-
(1992)
Antisense Res Dev
, vol.2
, pp. 315
-
-
Lavignon, M.1
Tounekti, N.2
Rayner, B.3
Imbach, J.L.4
Keith, G.5
Paoletti, J.6
Malvy, C.7
-
112
-
-
0028034890
-
In vitro inhibition of the pim-1 protooncogene by chimeric oligodeoxyribonucleotides composed of alpha- and beta-anomeric fragments
-
Gottikh M, Baud-Demattei MV, Lescot E, Giorgi-Renault S, Shabarova Z, Dautry F, Malvy C, Bertrand JR: In vitro inhibition of the pim-1 protooncogene by chimeric oligodeoxyribonucleotides composed of alpha- and beta-anomeric fragments. Gene 149:5, 1994
-
(1994)
Gene
, vol.149
, pp. 5
-
-
Gottikh, M.1
Baud-Demattei, M.V.2
Lescot, E.3
Giorgi-Renault, S.4
Shabarova, Z.5
Dautry, F.6
Malvy, C.7
Bertrand, J.R.8
-
113
-
-
0027168725
-
Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, Kawasaki AM, Cook PD, Freier SM: Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem 268:14514, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 14514
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
114
-
-
0029100397
-
Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration
-
Agrawal S, Zhang X, Lu Z, Zhao H, Tamburin JM, Yan J, Cai H, Diasio RB, Habus I, Jiang Z, Iyer RP, Yu D, Zhang R: Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration. Biochem Pharmacol 50:571, 1995
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 571
-
-
Agrawal, S.1
Zhang, X.2
Lu, Z.3
Zhao, H.4
Tamburin, J.M.5
Yan, J.6
Cai, H.7
Diasio, R.B.8
Habus, I.9
Jiang, Z.10
Iyer, R.P.11
Yu, D.12
Zhang, R.13
-
115
-
-
0031046722
-
Antisense gene inhibition by C-5-substituted deoxyuridine-containing oligodeoxynucleotides
-
Gutierrez AJ, Matteucci MD, Grant D, Matsumura S, Wagner RW, Froehler BC: Antisense gene inhibition by C-5-substituted deoxyuridine-containing oligodeoxynucleotides. Biochemistry 36:743, 1997
-
(1997)
Biochemistry
, vol.36
, pp. 743
-
-
Gutierrez, A.J.1
Matteucci, M.D.2
Grant, D.3
Matsumura, S.4
Wagner, R.W.5
Froehler, B.C.6
-
116
-
-
0029872147
-
A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA
-
Lewis JG, Lin KY, Kothavale A, Flanagan WM, Matteucci MD, DePrince RB, Mook RA Jr, Hendren RW, Wagner RW: A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. Proc Natl Acad Sci USA 93:3176, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3176
-
-
Lewis, J.G.1
Lin, K.Y.2
Kothavale, A.3
Flanagan, W.M.4
Matteucci, M.D.5
DePrince, R.B.6
Mook Jr., R.A.7
Hendren, R.W.8
Wagner, R.W.9
-
117
-
-
0027419756
-
Peptide nucleic acids (PNAs): Potential antisense and anti-gene agents
-
Nielsen PE, Egholm M, Berg RH, Buchardt O: Peptide nucleic acids (PNAs): Potential antisense and anti-gene agents. Anticancer Drug Des 8:53, 1993
-
(1993)
Anticancer Drug Des
, vol.8
, pp. 53
-
-
Nielsen, P.E.1
Egholm, M.2
Berg, R.H.3
Buchardt, O.4
-
118
-
-
0029132791
-
DNA analogues with nonphosphosphodiester backbones
-
Nielsen PE: DNA analogues with nonphosphosphodiester backbones. Annu Rev Biophys Biomol Struct 24:167, 1995
-
(1995)
Annu Rev Biophys Biomol Struct
, vol.24
, pp. 167
-
-
Nielsen, P.E.1
-
119
-
-
58149324674
-
Phospholipid membrane permeability of peptide nucleic acid
-
[corrected and republished with original paging, article originally printed in FEBS Lett 365:27,1995]
-
Wittung P, Kajanus J, Edwards K, Haaima G, Nielsen PE, Norden B, Malmstrom BG: Phospholipid membrane permeability of peptide nucleic acid [corrected and republished with original paging, article originally printed in FEBS Lett 365:27,1995]. FEBS Lett 375:27, 1995
-
(1995)
FEBS Lett
, vol.375
, pp. 27
-
-
Wittung, P.1
Kajanus, J.2
Edwards, K.3
Haaima, G.4
Nielsen, P.E.5
Norden, B.6
Malmstrom, B.G.7
-
120
-
-
0029891418
-
Circular oligonucleotides: New concepts in oligonucleotide design
-
Kool ET: Circular oligonucleotides: new concepts in oligonucleotide design. Annu Rev Biophys Biomol Struct 25:1, 1996
-
(1996)
Annu Rev Biophys Biomol Struct
, vol.25
, pp. 1
-
-
Kool, E.T.1
-
121
-
-
0029096025
-
An efficient strategy for the synthesis of circular RNA molecules
-
Beaudry D, Perreault JP: An efficient strategy for the synthesis of circular RNA molecules. Nucleic Acids Res 23:3064, 1995
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3064
-
-
Beaudry, D.1
Perreault, J.P.2
-
122
-
-
0029037839
-
Convergent DNA synthesis: A non-enzymatic dimerization approach to circular oligodeoxynucleotides
-
Rubin E, Rumney St, Wang S, Kool ET: Convergent DNA synthesis: A non-enzymatic dimerization approach to circular oligodeoxynucleotides. Nucleic Acids Res 23:3547, 1995
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3547
-
-
Rubin, E.1
Rumney, St.2
Wang, S.3
Kool, E.T.4
-
123
-
-
0028905315
-
Characterization of endothelin receptors in newborn piglet lung
-
Perreault T, Baribeau J: Characterization of endothelin receptors in newborn piglet lung. Am J Physiol 268:L607, 1995
-
(1995)
Am J Physiol
, vol.268
-
-
Perreault, T.1
Baribeau, J.2
-
124
-
-
0028244501
-
Circular RNA oligonucleotides. Synthesis, nucleic acid binding properties, and a comparison with circular DNAs
-
Wang S, Kool ET: Circular RNA oligonucleotides. Synthesis, nucleic acid binding properties, and a comparison with circular DNAs. Nucleic Acids Res 22:2326, 1994
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2326
-
-
Wang, S.1
Kool, E.T.2
-
125
-
-
0030789137
-
Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-kappaB p65) 'antisense' oligodeoxynucleotide
-
Benimetskaya L, Berton M, Kolbanovsky A, Benimetsky S, Stein CA: Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-kappaB p65) 'antisense' oligodeoxynucleotide. Nucleic Acids Res 25:2648, 1997
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2648
-
-
Benimetskaya, L.1
Berton, M.2
Kolbanovsky, A.3
Benimetsky, S.4
Stein, C.A.5
-
126
-
-
0030626275
-
Exogenous cellular delivery of ribozymes and ribozyme encoding DNAs
-
Castanotto D, Bertrand E, Rossi J: Exogenous cellular delivery of ribozymes and ribozyme encoding DNAs. Methods Mol Biol 74:429, 1997
-
(1997)
Methods Mol Biol
, vol.74
, pp. 429
-
-
Castanotto, D.1
Bertrand, E.2
Rossi, J.3
-
127
-
-
0027214126
-
A novel method to stabilise antisense oligonucleotides against exonuclease degradation
-
Khan IM, Coulson JM: A novel method to stabilise antisense oligonucleotides against exonuclease degradation. Nucleic Acids Res 21:4433, 1993
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 4433
-
-
Khan, I.M.1
Coulson, J.M.2
-
128
-
-
0028341661
-
Short antisense oligonucleotide-mediated inhibition is strongly dependent on oligo length and concentration but almost independent of location of the target sequence
-
Fakler B, Herlitze S, Amthor B, Zenner HP, Ruppersberg JP: Short antisense oligonucleotide-mediated inhibition is strongly dependent on oligo length and concentration but almost independent of location of the target sequence. J Biol Chem 269:16187, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 16187
-
-
Fakler, B.1
Herlitze, S.2
Amthor, B.3
Zenner, H.P.4
Ruppersberg, J.P.5
-
129
-
-
0026621339
-
Implication of RNA structure on antisense oligonucleotide hybridization kinetics
-
Lima WF, Monia BP, Ecker DJ, Freier SM: Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry 31:12055, 1992
-
(1992)
Biochemistry
, vol.31
, pp. 12055
-
-
Lima, W.F.1
Monia, B.P.2
Ecker, D.J.3
Freier, S.M.4
-
130
-
-
0030849094
-
The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity
-
Lima WF, Mohan V, Crooke ST: The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity. J Biol Chem 272:18191, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 18191
-
-
Lima, W.F.1
Mohan, V.2
Crooke, S.T.3
-
131
-
-
0031032603
-
Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity
-
Lima WF, Brown-Driver V, Fox M, Hanecak R, Bruice TW: Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity. J Biol Chem 272:626, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 626
-
-
Lima, W.F.1
Brown-Driver, V.2
Fox, M.3
Hanecak, R.4
Bruice, T.W.5
-
132
-
-
0026020219
-
Walking along human c-myc mRNA with antisense oligodeoxynucleotides: Maximum efficacy at the 5′ cap region
-
Bacon TA, Wickstrom E: Walking along human c-myc mRNA with antisense oligodeoxynucleotides: Maximum efficacy at the 5′ cap region. Oncogene Res 6:13, 1991
-
(1991)
Oncogene Res
, vol.6
, pp. 13
-
-
Bacon, T.A.1
Wickstrom, E.2
-
133
-
-
0030071190
-
Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides
-
Stewart AJ, Canitrot Y, Baracchini E, Dean NM, Deeley RG, Cole SP: Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides. Biochem Pharmacol 51:461, 1996
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 461
-
-
Stewart, A.J.1
Canitrot, Y.2
Baracchini, E.3
Dean, N.M.4
Deeley, R.G.5
Cole, S.P.6
-
134
-
-
0028037426
-
In vitro selection of antisense oligonucleotides targeted to a hairpin structure
-
Mishra RK, Toulme JJ: In vitro selection of antisense oligonucleotides targeted to a hairpin structure. C R Acad Sci III 317:977, 1994
-
(1994)
C R Acad Sci III
, vol.317
, pp. 977
-
-
Mishra, R.K.1
Toulme, J.J.2
-
135
-
-
0027289572
-
Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1
-
Sczakiel G, Homann M, Rittner K: Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1. Antisense Res Dev 3:45, 1993
-
(1993)
Antisense Res Dev
, vol.3
, pp. 45
-
-
Sczakiel, G.1
Homann, M.2
Rittner, K.3
-
136
-
-
0003038882
-
Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries
-
Ho SP, Bao Y, Lesher T, Malhotra R, Ma LY, Fluharty SJ, Sakai RR: Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries [see comments]. Nat Biotechnol 16:59, 1998
-
(1998)
Nat Biotechnol
, vol.16
, pp. 59
-
-
Ho, S.P.1
Bao, Y.2
Lesher, T.3
Malhotra, R.4
Ma, L.Y.5
Fluharty, S.J.6
Sakai, R.R.7
-
137
-
-
0030596527
-
Kinetic selectivity of complementary nucleic acids: Ber-abl-directed antisense RNA and ribozymes
-
Kronenwett R, Haas R, Sczakiel G: Kinetic selectivity of complementary nucleic acids: ber-abl-directed antisense RNA and ribozymes. J Mol Biol 259:632, 1996
-
(1996)
J Mol Biol
, vol.259
, pp. 632
-
-
Kronenwett, R.1
Haas, R.2
Sczakiel, G.3
-
138
-
-
0026770701
-
Predicting antisense oligonucleotide inhibitory efficacy: A computational approach using histograms and thermodynamic indices
-
Stull RA, Taylor LA, Szoka FC Jr: Predicting antisense oligonucleotide inhibitory efficacy: A computational approach using histograms and thermodynamic indices. Nucleic Acids Res 20:3501, 1992
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3501
-
-
Stull, R.A.1
Taylor, L.A.2
Szoka Jr., F.C.3
-
139
-
-
0030902471
-
Selecting effective antisense reagents on combinatorial oligonucleotide arrays
-
Milner N, Mir KU, Southern EM: Selecting effective antisense reagents on combinatorial oligonucleotide arrays [see comments]. Nat Biotechnol 15:537, 1997
-
(1997)
Nat Biotechnol
, vol.15
, pp. 537
-
-
Milner, N.1
Mir, K.U.2
Southern, E.M.3
-
140
-
-
24544459180
-
Direct in vivo detection of hybridization between antisense oligodeoxynucleotides and target mRNA
-
abstr, suppl 1
-
Sokol DL, Zhang X, Gewirtz AM: Direct in vivo detection of hybridization between antisense oligodeoxynucleotides and target mRNA. Blood 90:418b, 1997 (abstr, suppl 1)
-
(1997)
Blood
, vol.90
-
-
Sokol, D.L.1
Zhang, X.2
Gewirtz, A.M.3
-
141
-
-
0027759421
-
As nature intended? the uptake of DNA and oligonucleotides by eukaryotic cells
-
Bennett RM: As nature intended? The uptake of DNA and oligonucleotides by eukaryotic cells. Antisense Res Dev 3:235, 1993
-
(1993)
Antisense Res Dev
, vol.3
, pp. 235
-
-
Bennett, R.M.1
-
142
-
-
0000407290
-
Mechanism of oligonucleotide uptake by cells: Involvement of specific receptors?
-
Yakubov LA, Deeva EA, Zarytova VF, Ivanova EM, Ryte AS, Yurchenko LV, Vlassov VV: Mechanism of oligonucleotide uptake by cells: involvement of specific receptors? Proc Natl Acad Sci USA 86:6454, 1989
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6454
-
-
Yakubov, L.A.1
Deeva, E.A.2
Zarytova, V.F.3
Ivanova, E.M.4
Ryte, A.S.5
Yurchenko, L.V.6
Vlassov, V.V.7
-
143
-
-
0345570537
-
Characterization of oligonucleotide transport into living cells
-
Loke SL, Stein CA, Zhang XH, Mori K, Nakanishi M, Subasinghe C, Cohen JS, Neckers LM: Characterization of oligonucleotide transport into living cells. Proc Natl Acad Sci USA 86:3474, 1989
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3474
-
-
Loke, S.L.1
Stein, C.A.2
Zhang, X.H.3
Mori, K.4
Nakanishi, M.5
Subasinghe, C.6
Cohen, J.S.7
Neckers, L.M.8
-
144
-
-
0026058794
-
Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 gp120 to CD4
-
Stein CA, Neckers LM, Nair BC, Mumbauer S, Hoke G, Pal R: Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 gp120 to CD4. J Acquir Immune Defic Syndr 4:686, 1991
-
(1991)
J Acquir Immune Defic Syndr
, vol.4
, pp. 686
-
-
Stein, C.A.1
Neckers, L.M.2
Nair, B.C.3
Mumbauer, S.4
Hoke, G.5
Pal, R.6
-
145
-
-
0026839585
-
Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker
-
Geselowitz DA, Neckers LM: Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker. Antisense Res Dev 2:17, 1992
-
(1992)
Antisense Res Dev
, vol.2
, pp. 17
-
-
Geselowitz, D.A.1
Neckers, L.M.2
-
146
-
-
0027492473
-
Cellular pharmacology of phosphorothioate homooligodeoxynucleotides in human cells
-
Gao WY, Storm C, Egan W, Cheng YC: Cellular pharmacology of phosphorothioate homooligodeoxynucleotides in human cells. Mol Pharmacol 43:45, 1993
-
(1993)
Mol Pharmacol
, vol.43
, pp. 45
-
-
Gao, W.Y.1
Storm, C.2
Egan, W.3
Cheng, Y.C.4
-
147
-
-
0028956615
-
Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides
-
Beltinger C, Saragovi HU, Smith RM, LeSauteur L, Shah N, DeDionisio L, Christensen L, Raible A, Jarett L, Gewirtz AM: Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. J Clin Invest 95:1814, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1814
-
-
Beltinger, C.1
Saragovi, H.U.2
Smith, R.M.3
LeSauteur, L.4
Shah, N.5
DeDionisio, L.6
Christensen, L.7
Raible, A.8
Jarett, L.9
Gewirtz, A.M.10
-
148
-
-
0029146596
-
Uptake, intracellular distribution, and stability of oligodeoxynucleotide phosphorothioate by Schistosoma mansoni
-
Tao LF, Marx KA, Wongwit W, Jiang Z, Agrawal S, Coleman RM: Uptake, intracellular distribution, and stability of oligodeoxynucleotide phosphorothioate by Schistosoma mansoni. Antisense Res Dev 5:123, 1995
-
(1995)
Antisense Res Dev
, vol.5
, pp. 123
-
-
Tao, L.F.1
Marx, K.A.2
Wongwit, W.3
Jiang, Z.4
Agrawal, S.5
Coleman, R.M.6
-
149
-
-
0030841714
-
Transformed and immortalized cellular uptake of oligodeoxynucleoside phosphorothioates, 3′-alkylamino oligodeoxynucleotides, 2′-O-methyl oligoribonucleotides, oligodeoxynucleoside methylphosphonates, and peptide nucleic acids
-
Gray GD, Basu S, Wickstrom E: Transformed and immortalized cellular uptake of oligodeoxynucleoside phosphorothioates, 3′-alkylamino oligodeoxynucleotides, 2′-O-methyl oligoribonucleotides, oligodeoxynucleoside methylphosphonates, and peptide nucleic acids. Biochem Pharmacol 53:1465, 1997
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1465
-
-
Gray, G.D.1
Basu, S.2
Wickstrom, E.3
-
150
-
-
0027325137
-
Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides
-
Zhao Q, Matson S, Herrera CJ, Fisher E, Yu H, Krieg AM: Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides. Antisense Res Dev 3:53, 1993
-
(1993)
Antisense Res Dev
, vol.3
, pp. 53
-
-
Zhao, Q.1
Matson, S.2
Herrera, C.J.3
Fisher, E.4
Yu, H.5
Krieg, A.M.6
-
151
-
-
0030841036
-
Uptake and efflux of intact antisense phosphorothioate deoxyoligonucleotide directed against angiotensin receptors in bovine adrenal cells
-
Li B, Hughes JA, Phillips MI: Uptake and efflux of intact antisense phosphorothioate deoxyoligonucleotide directed against angiotensin receptors in bovine adrenal cells. Neurochem Int 31:393, 1997
-
(1997)
Neurochem Int
, vol.31
, pp. 393
-
-
Li, B.1
Hughes, J.A.2
Phillips, M.I.3
-
152
-
-
0029088625
-
Poor cellular uptake of antisense oligodeoxynucleotides: An obstacle to their use in chronic myeloid leukaemia
-
Clark RE: Poor cellular uptake of antisense oligodeoxynucleotides: An obstacle to their use in chronic myeloid leukaemia. Leuk Lymphoma 19:189, 1995
-
(1995)
Leuk Lymphoma
, vol.19
, pp. 189
-
-
Clark, R.E.1
-
153
-
-
0028062847
-
Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides
-
Dean NM, McKay R: Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides. Proc Natl Acad Sci USA 91:11762, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11762
-
-
Dean, N.M.1
McKay, R.2
-
154
-
-
0029207065
-
Microinjection of in vitro transcribed RNA and antisense oligonucleotides in mouse oocytes and early embryos to study the gain- And loss-of-function of genes
-
Kola I, Sumarsono SH: Microinjection of in vitro transcribed RNA and antisense oligonucleotides in mouse oocytes and early embryos to study the gain- and loss-of-function of genes. Methods Mol Biol 37:135, 1995
-
(1995)
Methods Mol Biol
, vol.37
, pp. 135
-
-
Kola, I.1
Sumarsono, S.H.2
-
155
-
-
0025798610
-
Intracellular distribution of microinjected antisense oligonucleotides
-
Leonetti JP, Mechti N, Degols G, Gagnor C, Lebleu B: Intracellular distribution of microinjected antisense oligonucleotides. Proc Natl Acad Sci USA 88:2702, 1991
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2702
-
-
Leonetti, J.P.1
Mechti, N.2
Degols, G.3
Gagnor, C.4
Lebleu, B.5
-
156
-
-
0030001042
-
Electroporation of synthetic oligodeoxynucleotides: A novel technique for ex vivo bone marrow purging
-
Bergan R, Hakim F, Schwartz GN, Kyle E, Cepada R, Szabo JM, Fowler D, Gress R, Neckers L: Electroporation of synthetic oligodeoxynucleotides: a novel technique for ex vivo bone marrow purging. Blood 88:731, 1996
-
(1996)
Blood
, vol.88
, pp. 731
-
-
Bergan, R.1
Hakim, F.2
Schwartz, G.N.3
Kyle, E.4
Cepada, R.5
Szabo, J.M.6
Fowler, D.7
Gress, R.8
Neckers, L.9
-
157
-
-
0030868484
-
Potent and selective gene inhibition using antisense oligodeoxynucleotides
-
Flanagan WM, Wagner RW: Potent and selective gene inhibition using antisense oligodeoxynucleotides. Mol Cell Biochem 172:213, 1997
-
(1997)
Mol Cell Biochem
, vol.172
, pp. 213
-
-
Flanagan, W.M.1
Wagner, R.W.2
-
158
-
-
0009599106
-
Calcium dependent cellular uptake of a c-myc antisense oligonucleotide
-
Wu-Pong S, Weiss TL, Hunt CA: Calcium dependent cellular uptake of a c-myc antisense oligonucleotide. Cell Mol Biol 40:843, 1994
-
(1994)
Cell Mol Biol
, vol.40
, pp. 843
-
-
Wu-Pong, S.1
Weiss, T.L.2
Hunt, C.A.3
-
159
-
-
0026132404
-
The binding of manganese(II) and zinc(II) to the synthetic oligonucleotide d(C-G-C-G-A-A-T-T-C-G-C-G)2.A 1H NMR study
-
Froystein NA, Sletten E: The binding of manganese(II) and zinc(II) to the synthetic oligonucleotide d(C-G-C-G-A-A-T-T-C-G-C-G)2.A 1H NMR study. Acta Chem Scand 45:219, 1991
-
(1991)
Acta Chem Scand
, vol.45
, pp. 219
-
-
Froystein, N.A.1
Sletten, E.2
-
160
-
-
0026877363
-
Liposomes as a drug delivery system for antisense oligonucleotides
-
Juliano RL, Akhtar S: Liposomes as a drug delivery system for antisense oligonucleotides. Antisense Res Dev 2:165, 1992
-
(1992)
Antisense Res Dev
, vol.2
, pp. 165
-
-
Juliano, R.L.1
Akhtar, S.2
-
161
-
-
0028501007
-
Gene transfer with synthetic cationic amphiphiles: Prospects for gene therapy
-
Behr JP: Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy. Bioconjug Chem 5:382, 1994
-
(1994)
Bioconjug Chem
, vol.5
, pp. 382
-
-
Behr, J.P.1
-
162
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B, Behr JP: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc Natl Acad Sci USA 92:7297, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7297
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
163
-
-
0030890748
-
Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
-
Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC Jr: Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry 36:3008, 1997
-
(1997)
Biochemistry
, vol.36
, pp. 3008
-
-
Wyman, T.B.1
Nicol, F.2
Zelphati, O.3
Scaria, P.V.4
Plank, C.5
Szoka Jr., F.C.6
-
164
-
-
0031036238
-
Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
-
Radler JO, Koltover I, Salditt T, Safinya CR: Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes [see comments]. Science 275:810, 1997
-
(1997)
Science
, vol.275
, pp. 810
-
-
Radler, J.O.1
Koltover, I.2
Salditt, T.3
Safinya, C.R.4
-
165
-
-
0029964866
-
Mechanism of oligonucleotide release from cationic liposomes
-
Zelphati O, Szoka FC Jr: Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 93:11493, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11493
-
-
Zelphati, O.1
Szoka Jr., F.C.2
-
166
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y, Szoka FC Jr: Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35:5616, 1996
-
(1996)
Biochemistry
, vol.35
, pp. 5616
-
-
Xu, Y.1
Szoka Jr., F.C.2
-
167
-
-
0031584865
-
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method
-
Aoki M, Morishita R, Higaki J, Moriguchi A, Kida I, Hayashi S, Matsushita H, Kaneda Y, Ogihara T: In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method. Biochem Biophys Res Commun 231:540, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 540
-
-
Aoki, M.1
Morishita, R.2
Higaki, J.3
Moriguchi, A.4
Kida, I.5
Hayashi, S.6
Matsushita, H.7
Kaneda, Y.8
Ogihara, T.9
-
168
-
-
0028910689
-
Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo
-
Desjardins J, Mata J, Brown T, Graham D, Zon G, Iversen P: Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo. J Drug Target 2:477, 1995
-
(1995)
J Drug Target
, vol.2
, pp. 477
-
-
Desjardins, J.1
Mata, J.2
Brown, T.3
Graham, D.4
Zon, G.5
Iversen, P.6
-
169
-
-
0027473513
-
Modification of antisense phosphodiester oligodeoxynucleotides by a 5′ cholesteryl moiety increases cellular association and improves efficacy
-
Krieg AM, Tonkinson J, Matson S, Zhao Q, Saxon M, Zhang LM, Bhanja U, Yakubov L, Stein CA: Modification of antisense phosphodiester oligodeoxynucleotides by a 5′ cholesteryl moiety increases cellular association and improves efficacy. Proc Natl Acad Sci USA 90:1048, 1993
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1048
-
-
Krieg, A.M.1
Tonkinson, J.2
Matson, S.3
Zhao, Q.4
Saxon, M.5
Zhang, L.M.6
Bhanja, U.7
Yakubov, L.8
Stein, C.A.9
-
170
-
-
0030294102
-
Enhanced delivery of synthetic oligonucleotides to human leukaemic cells by liposomes and immunoliposomes
-
Ma DD, Wei AQ: Enhanced delivery of synthetic oligonucleotides to human leukaemic cells by liposomes and immunoliposomes. Leuk Res 20:925, 1996
-
(1996)
Leuk Res
, vol.20
, pp. 925
-
-
Ma, D.D.1
Wei, A.Q.2
-
171
-
-
0032007293
-
Oligodeoxyribonucleotide uptake in primary human hematopoietic cells is enhanced by cationic lipids and depends on the hematopoietic cell subset
-
Kronenwett R, Steidl U, Kirsch M, Sczakiel G, Haas R: Oligodeoxyribonucleotide uptake in primary human hematopoietic cells is enhanced by cationic lipids and depends on the hematopoietic cell subset. Blood 91:852, 1998
-
(1998)
Blood
, vol.91
, pp. 852
-
-
Kronenwett, R.1
Steidl, U.2
Kirsch, M.3
Sczakiel, G.4
Haas, R.5
-
172
-
-
0029879998
-
Oligonucleotide targeting to alveolar macrophages by mannose receptor-mediated endocytosis
-
Liang WW, Shi X, Deshpande D, Malanga CJ, Rojanasakul Y: Oligonucleotide targeting to alveolar macrophages by mannose receptor-mediated endocytosis. Biochim Biophys Acta 1279:227, 1996
-
(1996)
Biochim Biophys Acta
, vol.1279
, pp. 227
-
-
Liang, W.W.1
Shi, X.2
Deshpande, D.3
Malanga, C.J.4
Rojanasakul, Y.5
-
173
-
-
0027353496
-
Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisense nucleotides: A novel approach for two-step radioimmunotherapy of cancer
-
Kuijpers WH, Bos ES, Kaspersen FM, Veeneman GH, van Boeckel CA: Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisense nucleotides: A novel approach for two-step radioimmunotherapy of cancer. Bioconjug Chem 4:94, 1993
-
(1993)
Bioconjug Chem
, vol.4
, pp. 94
-
-
Kuijpers, W.H.1
Bos, E.S.2
Kaspersen, F.M.3
Veeneman, G.H.4
Van Boeckel, C.A.5
-
174
-
-
0028013701
-
Antisense DNA delivery in vivo: Liver targeting by receptor-mediated uptake
-
Lu XM, Fischman AJ, Jyawook SL, Hendricks K, Tompkins RG, Yarmush ML: Antisense DNA delivery in vivo: Liver targeting by receptor-mediated uptake. J Nucl Med 35:269, 1994
-
(1994)
J Nucl Med
, vol.35
, pp. 269
-
-
Lu, X.M.1
Fischman, A.J.2
Jyawook, S.L.3
Hendricks, K.4
Tompkins, R.G.5
Yarmush, M.L.6
-
175
-
-
0026669605
-
Drug targeting: Synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates
-
Bonfils E, Depierreux C, Midoux P, Thuong NT, Monsigny M, Roche AC: Drug targeting: Synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates. Nucleic Acids Res 20:4621, 1992
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 4621
-
-
Bonfils, E.1
Depierreux, C.2
Midoux, P.3
Thuong, N.T.4
Monsigny, M.5
Roche, A.C.6
-
176
-
-
0025093209
-
Natural and phosphorothioate-modified oligodeoxyribonucleotides exhibit a non-random cellular distribution
-
Cerruzi M, Draper K, Schwartz J: Natural and phosphorothioate-modified oligodeoxyribonucleotides exhibit a non-random cellular distribution. Nucleosides Nucleotides 9:679, 1990
-
(1990)
Nucleosides Nucleotides
, vol.9
, pp. 679
-
-
Cerruzi, M.1
Draper, K.2
Schwartz, J.3
-
177
-
-
0027503286
-
Characterization of the nuclear binding sites of oligodeoxyribonucleotides and their analogs
-
Clarenc JP, Lebleu B, Leonetti JP: Characterization of the nuclear binding sites of oligodeoxyribonucleotides and their analogs. J Biol Chem 268:5600, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 5600
-
-
Clarenc, J.P.1
Lebleu, B.2
Leonetti, J.P.3
-
178
-
-
0028114851
-
Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide
-
Bongartz JP, Aubertin AM, Milhaud PG, Lebleu B: Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res 22:4681, 1994
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4681
-
-
Bongartz, J.P.1
Aubertin, A.M.2
Milhaud, P.G.3
Lebleu, B.4
-
179
-
-
0026755818
-
High-efficiency receptor-mediated delivery of small and large 48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles
-
Cotten M, Wagner E, Zatloukal K, Phillips S, Curiel DT, Birnstiel ML: High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. Proc Natl Acad Sci USA 89:6094, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6094
-
-
Cotten, M.1
Wagner, E.2
Zatloukal, K.3
Phillips, S.4
Curiel, D.T.5
Birnstiel, M.L.6
-
180
-
-
0026829648
-
Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway
-
Curiel DT, Agarwal S, Romer MU, Wagner E, Cotten M, Birnstiel ML, Boucher RC: Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway. Am J Respir Cell Mol Biol 6:247, 1992
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 247
-
-
Curiel, D.T.1
Agarwal, S.2
Romer, M.U.3
Wagner, E.4
Cotten, M.5
Birnstiel, M.L.6
Boucher, R.C.7
-
181
-
-
0029337127
-
Colocalizing ribozymes with substrate RNAs to increase their efficacy as gene inhibitors
-
Sullenger BA: Colocalizing ribozymes with substrate RNAs to increase their efficacy as gene inhibitors. Appl Biochem Biotechnol 54:57, 1995
-
(1995)
Appl Biochem Biotechnol
, vol.54
, pp. 57
-
-
Sullenger, B.A.1
-
182
-
-
0030810546
-
In vivo metabolic profile of a phosphorothioate Oligodeoxyribonucleotide
-
Temsamani J, Roskey A, Chaix C, Agrawal S: In vivo metabolic profile of a phosphorothioate Oligodeoxyribonucleotide. Antisense Nucleic Acid Drug Dev 7:159, 1997
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 159
-
-
Temsamani, J.1
Roskey, A.2
Chaix, C.3
Agrawal, S.4
-
183
-
-
0025743216
-
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice
-
Agrawal S, Temsamani J, Tang JY: Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. Proc Natl Acad Sci USA 88:7595, 1991
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7595
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
184
-
-
0030669520
-
Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues
-
Butler M, Stecker K, Bennett CF: Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues. Lab Invest 77:379, 1997
-
(1997)
Lab Invest
, vol.77
, pp. 379
-
-
Butler, M.1
Stecker, K.2
Bennett, C.F.3
-
185
-
-
0028136417
-
Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion
-
Iversen PL, Mata J, Tracewell WG, Zon G: Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion. Antisense Res Dev 4:43, 1994
-
(1994)
Antisense Res Dev
, vol.4
, pp. 43
-
-
Iversen, P.L.1
Mata, J.2
Tracewell, W.G.3
Zon, G.4
-
186
-
-
0028241377
-
Biodistribution and metabolism of internally 3H-labeled oligonucleotides. I. Comparison of a phosphodiester and a phosphorothioate
-
Sands H, Gorey-Feret LJ, Cocuzza AJ, Hobbs FW, Chidester D, Trainor GL: Biodistribution and metabolism of internally 3H-labeled oligonucleotides. I. Comparison of a phosphodiester and a phosphorothioate. Mol Pharmacol 45:932, 1994
-
(1994)
Mol Pharmacol
, vol.45
, pp. 932
-
-
Sands, H.1
Gorey-Feret, L.J.2
Cocuzza, A.J.3
Hobbs, F.W.4
Chidester, D.5
Trainor, G.L.6
-
187
-
-
0028897029
-
Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides
-
Srinivasan SK, Iversen P: Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides. J Clin Lab Anal 9:129, 1995
-
(1995)
J Clin Lab Anal
, vol.9
, pp. 129
-
-
Srinivasan, S.K.1
Iversen, P.2
-
188
-
-
0027729703
-
Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase I trial
-
Bayever E, Iversen PL, Bishop MR, Sharp JG, Tewary HK, Arneson MA, Pirruccello SJ, Ruddon RW, Kessinger A, Zon G, Armitage JO: Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial. Antisense Res Dev 3:383, 1993
-
(1993)
Antisense Res Dev
, vol.3
, pp. 383
-
-
Bayever, E.1
Iversen, P.L.2
Bishop, M.R.3
Sharp, J.G.4
Tewary, H.K.5
Arneson, M.A.6
Pirruccello, S.J.7
Ruddon, R.W.8
Kessinger, A.9
Zon, G.10
Armitage, J.O.11
-
189
-
-
0029127845
-
Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects
-
Zhang R, Van J, Shahinian H, Amin G, Lu Z, Liu T, Saag MS, Jiang Z, Temsamani J, Martin RR, Schechter PJ, Agrawal S, Diasio RB: Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects. Clin Pharmacol Ther 58:44, 1995
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 44
-
-
Zhang, R.1
Van, J.2
Shahinian, H.3
Amin, G.4
Lu, Z.5
Liu, T.6
Saag, M.S.7
Jiang, Z.8
Temsamani, J.9
Martin, R.R.10
Schechter, P.J.11
Agrawal, S.12
Diasio, R.B.13
-
190
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Stein CA, Cheng YC: Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 261:1004, 1993
-
(1993)
Science
, vol.261
, pp. 1004
-
-
Stein, C.A.1
Cheng, Y.C.2
-
191
-
-
0028596461
-
Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey
-
Galbraith WM, Hobson WC, Giclas PC, Schechter PJ, Agrawal S: Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey. Antisense Res Dev 4:201, 1994
-
(1994)
Antisense Res Dev
, vol.4
, pp. 201
-
-
Galbraith, W.M.1
Hobson, W.C.2
Giclas, P.C.3
Schechter, P.J.4
Agrawal, S.5
-
192
-
-
0030874388
-
Pharmacokinetics of a potential human cytomegalovirus therapeutic, a phosphorothioate oligonucleotide, after intravitreal injection in the rabbit
-
Leeds JM, Henry SP, Truong L, Zutshi A, Levin AA, Kornbrust D: Pharmacokinetics of a potential human cytomegalovirus therapeutic, a phosphorothioate oligonucleotide, after intravitreal injection in the rabbit. Drug Metab Dispos 25:921, 1997
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 921
-
-
Leeds, J.M.1
Henry, S.P.2
Truong, L.3
Zutshi, A.4
Levin, A.A.5
Kornbrust, D.6
-
193
-
-
0030890003
-
Crohn's trial shows the pros of antisense
-
Robertson D: Crohn's trial shows the pros of antisense [news]. Nat Biotechnol 15:209, 1997
-
(1997)
Nat Biotechnol
, vol.15
, pp. 209
-
-
Robertson, D.1
-
194
-
-
0026089494
-
Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: An in vitro study relevant to bone marrow purging
-
Calabretta B, Sims RB, Valtieri M, Caracciolo D, Szczylik C, Venturelli D, Ratajczak M, Beran M, Gewirtz AM: Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging. Proc Natl Acad Sci USA 88:2351, 1991
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2351
-
-
Calabretta, B.1
Sims, R.B.2
Valtieri, M.3
Caracciolo, D.4
Szczylik, C.5
Venturelli, D.6
Ratajczak, M.7
Beran, M.8
Gewirtz, A.M.9
-
195
-
-
0027070730
-
In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides
-
Ratajczak MZ, Kant JA, Luger SM, Hijiya N, Zhang J, Zon G, Gewirtz AM: In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides. Proc Natl Acad Sci USA 89:11823, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11823
-
-
Ratajczak, M.Z.1
Kant, J.A.2
Luger, S.M.3
Hijiya, N.4
Zhang, J.5
Zon, G.6
Gewirtz, A.M.7
-
196
-
-
0029816460
-
The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
-
Melo JV: The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment] [see comments]. Blood 88:2375, 1996
-
(1996)
Blood
, vol.88
, pp. 2375
-
-
Melo, J.V.1
-
197
-
-
0025883201
-
Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides
-
Szczylik C, Skorski T, Nicolaides NC, Manzella L, Malaguarnera L, Venturelli D, Gewirtz AM, Calabretta B: Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides. Science 253:562, 1991
-
(1991)
Science
, vol.253
, pp. 562
-
-
Szczylik, C.1
Skorski, T.2
Nicolaides, N.C.3
Manzella, L.4
Malaguarnera, L.5
Venturelli, D.6
Gewirtz, A.M.7
Calabretta, B.8
-
198
-
-
0026285617
-
Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligodeoxynucleotides
-
Skorski T, Szczylik C, Malaguarnera L, Calabretta B: Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligodeoxynucleotides. Folia Histochem Cytobiol 29:85, 1991
-
(1991)
Folia Histochem Cytobiol
, vol.29
, pp. 85
-
-
Skorski, T.1
Szczylik, C.2
Malaguarnera, L.3
Calabretta, B.4
-
199
-
-
0029588277
-
Effects of BCR-ABL antisense oligonucleotides (AS-ODN) on human chronic myeloid leukemic cells: AS-ODN as effective purging agents
-
Wu AG, Joshi SS, Chan WC, Iversen PL, Jackson JD, Kessinger A, Pirruccello SJ, Sanger WG, Sharp JG, Verbik DJ, Whalen VL, Bishop MR: Effects of BCR-ABL antisense oligonucleotides (AS-ODN) on human chronic myeloid leukemic cells: AS-ODN as effective purging agents. Leuk Lymphoma 20:67, 1995
-
(1995)
Leuk Lymphoma
, vol.20
, pp. 67
-
-
Wu, A.G.1
Joshi, S.S.2
Chan, W.C.3
Iversen, P.L.4
Jackson, J.D.5
Kessinger, A.6
Pirruccello, S.J.7
Sanger, W.G.8
Sharp, J.G.9
Verbik, D.J.10
Whalen, V.L.11
Bishop, M.R.12
-
200
-
-
0027213601
-
Elimination of clonogenic Philadelphia-positive cells using BCR-ABL antisense oligodeoxynucleotides
-
de Fabritiis P, Amadori S, Calabretta B, Mandelli F: Elimination of clonogenic Philadelphia-positive cells using BCR-ABL antisense oligodeoxynucleotides. Bone Marrow Transplant 12:261, 1993
-
(1993)
Bone Marrow Transplant
, vol.12
, pp. 261
-
-
De Fabritiis, P.1
Amadori, S.2
Calabretta, B.3
Mandelli, F.4
-
201
-
-
16944366178
-
Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells
-
de Fabritiis P, Skorski T, De Propris MS, Paggi MG, Nieborowska-Skorska M, Lisci A, Buffolino S, Campbell K, Geiser T, Calabretta B: Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells. Leukemia 11:811, 1997
-
(1997)
Leukemia
, vol.11
, pp. 811
-
-
De Fabritiis, P.1
Skorski, T.2
De Propris, M.S.3
Paggi, M.G.4
Nieborowska-Skorska, M.5
Lisci, A.6
Buffolino, S.7
Campbell, K.8
Geiser, T.9
Calabretta, B.10
-
202
-
-
0028922297
-
In vitro purging with BCR-ABL antisense oligodeoxynucleotides does not prevent haematologic reconstitution after autologous bone marrow transplantation
-
de Fabritis P, Amadori S, Petti MC, Mancini M, Montefusco E, Picardi A, Geiser T, Campbell K, Calabretta B, Mandelli F: In vitro purging with BCR-ABL antisense oligodeoxynucleotides does not prevent haematologic reconstitution after autologous bone marrow transplantation. Leukemia 9:662, 1995
-
(1995)
Leukemia
, vol.9
, pp. 662
-
-
De Fabritis, P.1
Amadori, S.2
Petti, M.C.3
Mancini, M.4
Montefusco, E.5
Picardi, A.6
Geiser, T.7
Campbell, K.8
Calabretta, B.9
Mandelli, F.10
-
203
-
-
0029992277
-
A comparison of the effect of bcr/abl breakpoint specific phosphothiorate oligodeoxynucleotides on colony formation by bcr/abl positive and negative, CD34 enriched mononuclear cell populations
-
Chasty R, Whetton A, Lucas G: A comparison of the effect of bcr/abl breakpoint specific phosphothiorate oligodeoxynucleotides on colony formation by bcr/abl positive and negative, CD34 enriched mononuclear cell populations. Leuk Res 20:391, 1996
-
(1996)
Leuk Res
, vol.20
, pp. 391
-
-
Chasty, R.1
Whetton, A.2
Lucas, G.3
-
204
-
-
0027203638
-
BCR-ABL antisense purging in chronic myeloid leukaemia
-
Kirkland MA, O'Brien SG, McDonald C, Davidson RJ, Cross NC, Goldman JM: BCR-ABL antisense purging in chronic myeloid leukaemia [letter; comment]. Lancet 342:614, 1993
-
(1993)
Lancet
, vol.342
, pp. 614
-
-
Kirkland, M.A.1
O'Brien, S.G.2
McDonald, C.3
Davidson, R.J.4
Cross, N.C.5
Goldman, J.M.6
-
205
-
-
0029074366
-
Sequence specificity on the growth suppression and induction of apoptosis of chronic myeloid leukemia cells by BCR-ABL anti-sense oligodeoxynucleoside phosphorothioates
-
Maekawa T, Kimura S, Hirakawa K, Murakami A, Zon G, Abe T: Sequence specificity on the growth suppression and induction of apoptosis of chronic myeloid leukemia cells by BCR-ABL anti-sense oligodeoxynucleoside phosphorothioates. Int J Cancer 62:63, 1995
-
(1995)
Int J Cancer
, vol.62
, pp. 63
-
-
Maekawa, T.1
Kimura, S.2
Hirakawa, K.3
Murakami, A.4
Zon, G.5
Abe, T.6
-
206
-
-
0028790750
-
Specific antisense oligomer anti Bcr-abl junctions in chronic myeloid leukemia: A cell cycle analysis and CFU-GM study
-
Mahon FX, Belloc F, Vianes I, Barbot C, Boiron JM, Cowen D, Lacombe F, Brizard A, Bilhou-Nabera C, Bernard P, Braustet A, Reiffers J: Specific antisense oligomer anti Bcr-abl junctions in chronic myeloid leukemia: A cell cycle analysis and CFU-GM study. Leuk Lymphoma 19:423, 1995
-
(1995)
Leuk Lymphoma
, vol.19
, pp. 423
-
-
Mahon, F.X.1
Belloc, F.2
Vianes, I.3
Barbot, C.4
Boiron, J.M.5
Cowen, D.6
Lacombe, F.7
Brizard, A.8
Bilhou-Nabera, C.9
Bernard, P.10
Braustet, A.11
Reiffers, J.12
-
207
-
-
0029618209
-
Inhibition of chronic myelogenous leukemia cells harboring a BCR-ABL B3A2 junction by antisense oligonucleotides targeted at the B2A2 junction
-
Mahon FX, Ripoche J, Pigeonnier V, Jazwiec B, Pigneux A, Moreau JF, Reiffers J: Inhibition of chronic myelogenous leukemia cells harboring a BCR-ABL B3A2 junction by antisense oligonucleotides targeted at the B2A2 junction. Exp Hematol 23:1606, 1995
-
(1995)
Exp Hematol
, vol.23
, pp. 1606
-
-
Mahon, F.X.1
Ripoche, J.2
Pigeonnier, V.3
Jazwiec, B.4
Pigneux, A.5
Moreau, J.F.6
Reiffers, J.7
-
208
-
-
0028586823
-
Antisense BCR-ABL oligomers cause non-specific inhibition of chronic myeloid leukemia cell lines
-
O'Brien SG, Kirkland MA, Melo JV, Rao MH, Davidson RJ, McDonald C, Goldman JM: Antisense BCR-ABL oligomers cause non-specific inhibition of chronic myeloid leukemia cell lines. Leukemia 8:2156, 1994
-
(1994)
Leukemia
, vol.8
, pp. 2156
-
-
O'Brien, S.G.1
Kirkland, M.A.2
Melo, J.V.3
Rao, M.H.4
Davidson, R.J.5
McDonald, C.6
Goldman, J.M.7
-
209
-
-
0028945287
-
Phosphorothioate BCR-ABL antisense oligonucleotides induce cell death, but fail to reduce cellular bcr-abl protein levels
-
Smetsers TF, van de Locht LT, Pennings AH, Wessels HM, de Witte TM, Mensink EJ: Phosphorothioate BCR-ABL antisense oligonucleotides induce cell death, but fail to reduce cellular bcr-abl protein levels. Leukemia 9:118, 1995
-
(1995)
Leukemia
, vol.9
, pp. 118
-
-
Smetsers, T.F.1
Van De Locht, L.T.2
Pennings, A.H.3
Wessels, H.M.4
De Witte, T.M.5
Mensink, E.J.6
-
210
-
-
0028810987
-
BCR-ABL antisense oligodeoxyribonucleotides suppress the growth of leukemic and normal hematopoietic cells by a sequence-specific but nonantisense mechanism
-
Vaerman JL, Lammineur C, Moureau P, Lewalle P, Deldime F, Blumenfeld M, Maniat P: BCR-ABL antisense oligodeoxyribonucleotides suppress the growth of leukemic and normal hematopoietic cells by a sequence-specific but nonantisense mechanism. Blood 86:3891, 1995
-
(1995)
Blood
, vol.86
, pp. 3891
-
-
Vaerman, J.L.1
Lammineur, C.2
Moureau, P.3
Lewalle, P.4
Deldime, F.5
Blumenfeld, M.6
Maniat, P.7
-
211
-
-
0029838829
-
Multi-unit anti-BCR-ABL ribozyme therapy in chronic myelogenous leukemia
-
Leopold LH, Shore SK, Reddy EP: Multi-unit anti-BCR-ABL ribozyme therapy in chronic myelogenous leukemia. Leuk Lymphoma 22:365, 1996
-
(1996)
Leuk Lymphoma
, vol.22
, pp. 365
-
-
Leopold, L.H.1
Shore, S.K.2
Reddy, E.P.3
-
212
-
-
0028047536
-
Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs
-
Lange W, Daskalakis M, Finke J, Dolken G: Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs. FEBS Lett 338:175, 1994
-
(1994)
FEBS Lett
, vol.338
, pp. 175
-
-
Lange, W.1
Daskalakis, M.2
Finke, J.3
Dolken, G.4
-
213
-
-
0028318142
-
Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences
-
Pachuk CJ, Yoon K, Moelling K, Coney LR: Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences. Nucleic Acids Res 22:301, 1994
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 301
-
-
Pachuk, C.J.1
Yoon, K.2
Moelling, K.3
Coney, L.R.4
-
214
-
-
0031453998
-
Gene therapy for chronic myelogenous leukemia (CML): A retroviral vector that renders hematopoietic progenitors methotrexate-resistant and CML progenitors functionally normal and nontumorigenic in vivo
-
Zhao RC, McIvor RS, Griffin JD, Verfaillie CM: Gene therapy for chronic myelogenous leukemia (CML): A retroviral vector that renders hematopoietic progenitors methotrexate-resistant and CML progenitors functionally normal and nontumorigenic in vivo. Blood 90:4687, 1997
-
(1997)
Blood
, vol.90
, pp. 4687
-
-
Zhao, R.C.1
McIvor, R.S.2
Griffin, J.D.3
Verfaillie, C.M.4
-
215
-
-
0028183180
-
Suppression of Philadelphia 1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide
-
Skorski T, Nieborowska-Skorska M, Nicolaides NC, Szczylik C, Iversen P, Iozzo RV, Zon G, Calabretta B: Suppression of Philadelphia 1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide. Proc Natl Acad Sci USA91:4504, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4504
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Nicolaides, N.C.3
Szczylik, C.4
Iversen, P.5
Iozzo, R.V.6
Zon, G.7
Calabretta, B.8
-
216
-
-
0027170689
-
Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide
-
Skorski T, Nieborowska-Skorska M, Barletta C, Malaguarnera L, Szcyzlik C, Chen ST, Lange B, Calabretta B: Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide. J Clin Invest 92:194, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 194
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Barletta, C.3
Malaguarnera, L.4
Szcyzlik, C.5
Chen, S.T.6
Lange, B.7
Calabretta, B.8
-
217
-
-
0030614494
-
Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides
-
Skorski T, Nieborowska-Skorska M, Wlodarski P, Perrotti D, Hoser G, Kawiak J, Majewski M, Christensen L, Iozzo RV, Calabretta B: Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides [see comments]. J Natl Cancer Inst 89:124, 1997
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 124
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Wlodarski, P.3
Perrotti, D.4
Hoser, G.5
Kawiak, J.6
Majewski, M.7
Christensen, L.8
Iozzo, R.V.9
Calabretta, B.10
-
218
-
-
0027277061
-
BCR-ABL gene rearrangement and expression of primitive hematopoietic progenitors in chronic myeloid leukemia
-
Bedi A, Zehnbauer BA, Collector MI, Barber JP, Zicha MS, Sharkis SJ, Jones RJ: BCR-ABL gene rearrangement and expression of primitive hematopoietic progenitors in chronic myeloid leukemia. Blood 81:2898, 1993
-
(1993)
Blood
, vol.81
, pp. 2898
-
-
Bedi, A.1
Zehnbauer, B.A.2
Collector, M.I.3
Barber, J.P.4
Zicha, M.S.5
Sharkis, S.J.6
Jones, R.J.7
-
219
-
-
0028256425
-
Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
-
Bedi A, Zehnbauer BA, Barber JP, Sharkis SJ, Jones RJ: Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 83:2038, 1994
-
(1994)
Blood
, vol.83
, pp. 2038
-
-
Bedi, A.1
Zehnbauer, B.A.2
Barber, J.P.3
Sharkis, S.J.4
Jones, R.J.5
-
220
-
-
0027979832
-
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
-
[published erratum appears in Blood 83:3835,1994]
-
McGahon A, Bissonnette R, Schmitt M, Cotter KM, Green DR, Cotter TG: BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death [published erratum appears in Blood 83:3835,1994]. Blood 83:1179, 1994
-
(1994)
Blood
, vol.83
, pp. 1179
-
-
McGahon, A.1
Bissonnette, R.2
Schmitt, M.3
Cotter, K.M.4
Green, D.R.5
Cotter, T.G.6
-
221
-
-
0030052385
-
Structure and function of the proteins encoded by the myb gene family
-
Kanei-Ishii C, Nomura T, Ogata K, Sarai A, Yasukawa T, Tashiro S, Takahashi T, Tanaka Y, Ishii S: Structure and function of the proteins encoded by the myb gene family. Curr Top Microbiol Immunol 211:89, 1996
-
(1996)
Curr Top Microbiol Immunol
, vol.211
, pp. 89
-
-
Kanei-Ishii, C.1
Nomura, T.2
Ogata, K.3
Sarai, A.4
Yasukawa, T.5
Tashiro, S.6
Takahashi, T.7
Tanaka, Y.8
Ishii, S.9
-
222
-
-
0027506077
-
Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1
-
Nomura N, Zu YL, Maekawa T, Tabata S, Akiyama T, Ishii S: Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1. J Biol Chem 268:4259, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 4259
-
-
Nomura, N.1
Zu, Y.L.2
Maekawa, T.3
Tabata, S.4
Akiyama, T.5
Ishii, S.6
-
223
-
-
0023737377
-
Viral myb oncogene encodes a sequence-specific DNA-binding activity
-
Biedenkapp H, Borgmeyer U, Sippel AE, Klempnauer KH: Viral myb oncogene encodes a sequence-specific DNA-binding activity. Nature 335:835, 1988
-
(1988)
Nature
, vol.335
, pp. 835
-
-
Biedenkapp, H.1
Borgmeyer, U.2
Sippel, A.E.3
Klempnauer, K.H.4
-
224
-
-
0032521541
-
Myb and Ets proteins are candidate regulators of c-kit expression in human hematopoietic cells
-
Ratajczak MZ, Perrotti D, Melotti P, Powzaniuk M, Calabretta B, Onodera K, Kregenow DA, Machalinski B, Gewirtz AM: Myb and Ets proteins are candidate regulators of c-kit expression in human hematopoietic cells. Blood 91:1934, 1998
-
(1998)
Blood
, vol.91
, pp. 1934
-
-
Ratajczak, M.Z.1
Perrotti, D.2
Melotti, P.3
Powzaniuk, M.4
Calabretta, B.5
Onodera, K.6
Kregenow, D.A.7
Machalinski, B.8
Gewirtz, A.M.9
-
225
-
-
0026589374
-
Expression of the CD4 gene requires a Myb transcription factor
-
Siu G, Wurster AL, Lipsick JS, Hedrick SM: Expression of the CD4 gene requires a Myb transcription factor. Mol Cell Biol 12:1592, 1992
-
(1992)
Mol Cell Biol
, vol.12
, pp. 1592
-
-
Siu, G.1
Wurster, A.L.2
Lipsick, J.S.3
Hedrick, S.M.4
-
226
-
-
0028006528
-
Regulation of the expression of the hematopoietic stem cell antigen CD34: Role of c-myb
-
Melotti P, Ku DH, Calabretta B: Regulation of the expression of the hematopoietic stem cell antigen CD34: Role of c-myb. J Exp Med 179:1023, 1994
-
(1994)
J Exp Med
, vol.179
, pp. 1023
-
-
Melotti, P.1
Ku, D.H.2
Calabretta, B.3
-
227
-
-
0024270537
-
A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro
-
Gewirtz AM, Calabretta B: A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 242:1303, 1988
-
(1988)
Science
, vol.242
, pp. 1303
-
-
Gewirtz, A.M.1
Calabretta, B.2
-
228
-
-
0024475427
-
G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb
-
Gewirtz AM, Anfossi G, Venrurelli D, Valpreda S, Sims R, Calabretta B: G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science 245:180, 1989
-
(1989)
Science
, vol.245
, pp. 180
-
-
Gewirtz, A.M.1
Anfossi, G.2
Venrurelli, D.3
Valpreda, S.4
Sims, R.5
Calabretta, B.6
-
229
-
-
0025128971
-
Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis
-
Caracciolo D, Venturelli D, Valtieri M, Peschle C, Gewirtz AM, Calabretta B: Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis. J Clin Invest 85:55, 1990
-
(1990)
J Clin Invest
, vol.85
, pp. 55
-
-
Caracciolo, D.1
Venturelli, D.2
Valtieri, M.3
Peschle, C.4
Gewirtz, A.M.5
Calabretta, B.6
-
230
-
-
0025821494
-
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
-
Mucenski ML, McLain K, Kier AB, Swerdlow SH, Schreiner CM, Miller TA, Pietryga DW, Scott WJ Jr, Potter SS: A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 65:677, 1991
-
(1991)
Cell
, vol.65
, pp. 677
-
-
Mucenski, M.L.1
McLain, K.2
Kier, A.B.3
Swerdlow, S.H.4
Schreiner, C.M.5
Miller, T.A.6
Pietryga, D.W.7
Scott Jr., W.J.8
Potter, S.S.9
-
231
-
-
0040668827
-
An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines
-
Anfossi G, Gewirtz AM, Calabretta B: An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci USA 86:3379, 1989
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3379
-
-
Anfossi, G.1
Gewirtz, A.M.2
Calabretta, B.3
-
232
-
-
0029992843
-
The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis
-
Melotti P, Calabretta B: The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis. Proc Natl Acad Sci USA 93:5313, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5313
-
-
Melotti, P.1
Calabretta, B.2
-
233
-
-
0029851211
-
Complex regulation of human c-kit transcription by promoter repressers, activators, and specific myb elements
-
Vandenbark GR, Chen Y, Friday E, Pavlik K, Anthony B, deCastro C, Kaufman RE: Complex regulation of human c-kit transcription by promoter repressers, activators, and specific myb elements. Cell Growth Differ 7:1383, 1996
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1383
-
-
Vandenbark, G.R.1
Chen, Y.2
Friday, E.3
Pavlik, K.4
Anthony, B.5
DeCastro, C.6
Kaufman, R.E.7
-
234
-
-
0032519768
-
c-kit ligand and Flt3 ligand: Stem/ progenitor cell factors with overlapping yet distinct activities
-
Lyman SD, Jacobsen SE: c-kit ligand and Flt3 ligand: stem/ progenitor cell factors with overlapping yet distinct activities. Blood 91:1101, 1998
-
(1998)
Blood
, vol.91
, pp. 1101
-
-
Lyman, S.D.1
Jacobsen, S.E.2
-
235
-
-
0027534243
-
Apoptosis and hematopiesis in murine fetal liver
-
Yu H, Bauer B, Lipke GK, Phillips RL, Van Zant G: Apoptosis and hematopiesis in murine fetal liver. Blood 81:373, 1993
-
(1993)
Blood
, vol.81
, pp. 373
-
-
Yu, H.1
Bauer, B.2
Lipke, G.K.3
Phillips, R.L.4
Van Zant, G.5
-
236
-
-
0028041311
-
The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2
-
Carson WE, Haldar S, Baiocchi RA, Croce CM, Caligiuri MA: The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc Natl Acad Sci USA 91:7553, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7553
-
-
Carson, W.E.1
Haldar, S.2
Baiocchi, R.A.3
Croce, C.M.4
Caligiuri, M.A.5
-
237
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
Sawyers CL, Callahan W, Witte ON: Dominant negative MYC blocks transformation by ABL oncogenes. Cell 70:901, 1992
-
(1992)
Cell
, vol.70
, pp. 901
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
238
-
-
0028286140
-
Differential complementation of Bcr-Abl point mutants with c-Myc
-
Afar DE, Goga A, McLaughlin J, Witte ON, Sawyers CL: Differential complementation of Bcr-Abl point mutants with c-Myc. Science 264:424, 1994
-
(1994)
Science
, vol.264
, pp. 424
-
-
Afar, D.E.1
Goga, A.2
McLaughlin, J.3
Witte, O.N.4
Sawyers, C.L.5
-
239
-
-
0030937825
-
Antileukemia effect of c-myc N3′ → p5′ phosphoramidate antisense oligonucleotides in vivo
-
Skorski T, Perrotti D, Nieborowska-Skorska M, Gryaznov S, Calabretta B: Antileukemia effect of c-myc N3′ → p5′ phosphoramidate antisense oligonucleotides in vivo. Proc Natl Acad Sci USA 94:3966, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3966
-
-
Skorski, T.1
Perrotti, D.2
Nieborowska-Skorska, M.3
Gryaznov, S.4
Calabretta, B.5
-
240
-
-
0029768861
-
Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice
-
Skorski T, Nieborowska-Skorska M, Wlodarski P, Zon G, Iozzo RV, Calabretta B: Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice. Blood 88:1005, 1996
-
(1996)
Blood
, vol.88
, pp. 1005
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Wlodarski, P.3
Zon, G.4
Iozzo, R.V.5
Calabretta, B.6
-
241
-
-
0342596009
-
Vav: Function and regulation in hematopoietic cell signaling
-
Bonnefoy-Berard N, Munshi A, Yron I, Wu S, Collins TL, Deckert M, Shalom-Barak T, Giampa L, Herben E, Hernandez J, Meller N, Couture C, Altman A: Vav: Function and regulation in hematopoietic cell signaling. Stem Cells 14:250, 1996
-
(1996)
Stem Cells
, vol.14
, pp. 250
-
-
Bonnefoy-Berard, N.1
Munshi, A.2
Yron, I.3
Wu, S.4
Collins, T.L.5
Deckert, M.6
Shalom-Barak, T.7
Giampa, L.8
Herben, E.9
Hernandez, J.10
Meller, N.11
Couture, C.12
Altman, A.13
-
242
-
-
0026762434
-
vav: A molecule for all haemopoiesis?
-
Katzav S: vav: A molecule for all haemopoiesis? Br J Haematol 81:141, 1992
-
(1992)
Br J Haematol
, vol.81
, pp. 141
-
-
Katzav, S.1
-
243
-
-
0027375858
-
Inhibition of hematopoietic development from embryonic stem cells by antisense vav RNA
-
Wulf GM, Adra CN, Um B: Inhibition of hematopoietic development from embryonic stem cells by antisense vav RNA. EMBO J 12:5065, 1993
-
(1993)
EMBO J
, vol.12
, pp. 5065
-
-
Wulf, G.M.1
Adra, C.N.2
Um, B.3
-
244
-
-
0028670479
-
Hematopoietic development of vav-/- Mouse embryonic stem cells
-
Zhang R, Tsai FY, Orkin SH: Hematopoietic development of vav-/- mouse embryonic stem cells. Proc Natl Acad Sci USA 91:12755, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12755
-
-
Zhang, R.1
Tsai, F.Y.2
Orkin, S.H.3
-
245
-
-
0028915948
-
Defective signalling through the T- And B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
-
Zhang R, Alt FW, Davidson L, Orkin SH, Swat W: Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene. Nature 374:470, 1995
-
(1995)
Nature
, vol.374
, pp. 470
-
-
Zhang, R.1
Alt, F.W.2
Davidson, L.3
Orkin, S.H.4
Swat, W.5
-
246
-
-
0028859034
-
The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro
-
Zmuidzinas A, Fischer KD, Lira SA, Forrester L, Bryant S, Bernstein A, Barbacid M: The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro. EMBO J 14:1, 1995
-
(1995)
EMBO J
, vol.14
, pp. 1
-
-
Zmuidzinas, A.1
Fischer, K.D.2
Lira, S.A.3
Forrester, L.4
Bryant, S.5
Bernstein, A.6
Barbacid, M.7
-
247
-
-
0027999617
-
Structure and function of p53 in normal cells and their aberrations in cancer cells: Projection on the hematologic cell lineages
-
Prokocimer M, Rotter V: Structure and function of p53 in normal cells and their aberrations in cancer cells: Projection on the hematologic cell lineages. Blood 84:2391, 1994
-
(1994)
Blood
, vol.84
, pp. 2391
-
-
Prokocimer, M.1
Rotter, V.2
-
248
-
-
0028231892
-
Oligonucleotides in the treatment of leukemia
-
Bayever E, Iversen P: Oligonucleotides in the treatment of leukemia. Hematol Oncol 12:9, 1994
-
(1994)
Hematol Oncol
, vol.12
, pp. 9
-
-
Bayever, E.1
Iversen, P.2
-
249
-
-
0028706884
-
Antisense oligonucleotide OL (1) p53 for in vitro purging of autologous bone marrow in acute myelogenous leukemia
-
Bishop MR, Warkentin PI, Jackson JD, Bayever E, Iversen PL, Whalen VI, Lastovica J, Haines K, Kessinger A: Antisense oligonucleotide OL (1) p53 for in vitro purging of autologous bone marrow in acute myelogenous leukemia. Prog Clin Biol Res 389:183, 1994
-
(1994)
Prog Clin Biol Res
, vol.389
, pp. 183
-
-
Bishop, M.R.1
Warkentin, P.I.2
Jackson, J.D.3
Bayever, E.4
Iversen, P.L.5
Whalen, V.I.6
Lastovica, J.7
Haines, K.8
Kessinger, A.9
-
250
-
-
9244223546
-
Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies
-
Bishop MR, Iversen PL, Bayever E, Sharp JG, Greiner TC, Copple BL, Ruddon R, Zon G, Spinolo J, Arneson M, Armitage JO, Kessinger A: Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies [see comments]. J Clin Oncol 14:1320, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 1320
-
-
Bishop, M.R.1
Iversen, P.L.2
Bayever, E.3
Sharp, J.G.4
Greiner, T.C.5
Copple, B.L.6
Ruddon, R.7
Zon, G.8
Spinolo, J.9
Arneson, M.10
Armitage, J.O.11
Kessinger, A.12
-
251
-
-
9044225527
-
BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy
-
Reed JC, Miyashita T, Takayama S, Wang HG, Sato T, Krajewski S, Aime-Sempe C, Bodrug S, Kitada S, Hanada M: BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy. J Cell Biochem 60:23, 1996
-
(1996)
J Cell Biochem
, vol.60
, pp. 23
-
-
Reed, J.C.1
Miyashita, T.2
Takayama, S.3
Wang, H.G.4
Sato, T.5
Krajewski, S.6
Aime-Sempe, C.7
Bodrug, S.8
Kitada, S.9
Hanada, M.10
-
252
-
-
0028066802
-
Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model
-
Cotter FE, Johnson P, Hall P, Pocock C, al Mahdi N, Cowell JK, Morgan G: Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model. Oncogene 9:3049, 1994
-
(1994)
Oncogene
, vol.9
, pp. 3049
-
-
Cotter, F.E.1
Johnson, P.2
Hall, P.3
Pocock, C.4
Al Mahdi, N.5
Cowell, J.K.6
Morgan, G.7
-
253
-
-
0031563773
-
Oligonucleotide inhibitors of human thrombin that bind distinct epitopes
-
Tasset DM, Kubik MF, Steiner W: Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. J Mol Biol 272:688, 1997
-
(1997)
J Mol Biol
, vol.272
, pp. 688
-
-
Tasset, D.M.1
Kubik, M.F.2
Steiner, W.3
-
254
-
-
0030829919
-
Inhibition of coagulation by a phosphorothioate oligonucleotide
-
Henry SP, Novotny W, Leeds J, Auletta C, Kornbrust DJ: Inhibition of coagulation by a phosphorothioate oligonucleotide. Antisense Nucleic Acid Drug Dev 7:503, 1997
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 503
-
-
Henry, S.P.1
Novotny, W.2
Leeds, J.3
Auletta, C.4
Kornbrust, D.J.5
-
255
-
-
0029811512
-
On the quality control of antisense oligonucleotides
-
Eckstein F, Krieg AM, Stein CA, Agrawal S, Beaucage S, Cook PD, Crooke S, Gait MJ, Gewirtz A, Helene C, Miller P, Narayanan R, Nicolin A, Nielsen P, Ohtsuka E, Seliger H, Stec W, Tidd D, Wagner R, Zon J: On the quality control of antisense oligonucleotides [editorial]. Antisense Nucleic Acid Drug Dev 6:149, 1996
-
(1996)
Antisense Nucleic Acid Drug Dev
, vol.6
, pp. 149
-
-
Eckstein, F.1
Krieg, A.M.2
Stein, C.A.3
Agrawal, S.4
Beaucage, S.5
Cook, P.D.6
Crooke, S.7
Gait, M.J.8
Gewirtz, A.9
Helene, C.10
Miller, P.11
Narayanan, R.12
Nicolin, A.13
Nielsen, P.14
Ohtsuka, E.15
Seliger, H.16
Stec, W.17
Tidd, D.18
Wagner, R.19
Zon, J.20
more..
-
257
-
-
0028882560
-
The state of the art in antisense research
-
Wagner RW: The state of the art in antisense research. Nat Med 1:1116, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1116
-
-
Wagner, R.W.1
-
258
-
-
0030951966
-
A roundtable on the state of the industry
-
Antisense '97
-
Antisense '97: A roundtable on the state of the industry. Nat Biotechnol 15:519, 1997
-
(1997)
Nat Biotechnol
, vol.15
, pp. 519
-
-
-
259
-
-
0030266476
-
Perturbing gene expression with oligodeoxynucleo-tides: Research and potential therapeutic applications
-
Gewirtz AM: Perturbing gene expression with oligodeoxynucleo- tides: Research and potential therapeutic applications. Mt Sinai J Med 63:372, 1996
-
(1996)
Mt Sinai J Med
, vol.63
, pp. 372
-
-
Gewirtz, A.M.1
-
260
-
-
0029087973
-
Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O
-
Spiller DG, Tidd DM: Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O. Antisense Res Dev 5:13, 1995
-
(1995)
Antisense Res Dev
, vol.5
, pp. 13
-
-
Spiller, D.G.1
Tidd, D.M.2
-
261
-
-
0030872683
-
Temperature and salt dependence of higher order structure formation by antisense c-myc and c-myb phosphorothioate oligodeoxyribonucleotides containing tetraguanylate tracts
-
Basu S, Wickstrom E: Temperature and salt dependence of higher order structure formation by antisense c-myc and c-myb phosphorothioate oligodeoxyribonucleotides containing tetraguanylate tracts. Nucleic Acids Res 25:1327, 1997
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1327
-
-
Basu, S.1
Wickstrom, E.2
-
262
-
-
0028863799
-
Contribution of sequence and phosphorothioate content to inhibition of cell growth and adhesion caused by c-myc antisense oligomers
-
Chavany C, Connell Y, Neckers L: Contribution of sequence and phosphorothioate content to inhibition of cell growth and adhesion caused by c-myc antisense oligomers. Mol Pharmacol 48:738, 1995
-
(1995)
Mol Pharmacol
, vol.48
, pp. 738
-
-
Chavany, C.1
Connell, Y.2
Neckers, L.3
-
263
-
-
0028182435
-
Erroneous results of 3H-thymidine incorporation are related to position of thymidine residues in oligodeoxynucleotides
-
Mouthon MA, Mitjavila MT, Marquet J, Vainchenker W, Wendung F: Erroneous results of 3H-thymidine incorporation are related to position of thymidine residues in oligodeoxynucleotides. Exp Hematol 22:384, 1994
-
(1994)
Exp Hematol
, vol.22
, pp. 384
-
-
Mouthon, M.A.1
Mitjavila, M.T.2
Marquet, J.3
Vainchenker, W.4
Wendung, F.5
-
264
-
-
0028810987
-
BCR-ABL antisense oligodeoxyribonucleotides suppress the growth of leukemic and normal hematopoietic cells by a sequence-specific but nonantisense mechanism
-
Vaerman JL, Lammineur C, Moureau P, Lewalle P, Deldime F, Blumenfeld M, Maniat P: BCR-ABL antisense oligodeoxyribonucleotides suppress the growth of leukemic and normal hematopoietic cells by a sequence-specific but nonantisense mechanism [see comments]. Blood 86:3891, 1995
-
(1995)
Blood
, vol.86
, pp. 3891
-
-
Vaerman, J.L.1
Lammineur, C.2
Moureau, P.3
Lewalle, P.4
Deldime, F.5
Blumenfeld, M.6
Maniat, P.7
-
266
-
-
0027319530
-
Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells
-
Yaswen P, Stampfer M, Ghosh K, Cohen J: Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells. Antisense Res Dev 3:67, 1993
-
(1993)
Antisense Res Dev
, vol.3
, pp. 67
-
-
Yaswen, P.1
Stampfer, M.2
Ghosh, K.3
Cohen, J.4
-
267
-
-
0026310571
-
Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides
-
Ho PT, Ishiguro K, Wickstrom E, Sartorelli AC: Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides. Antisense Res Dev 1:329, 1991
-
(1991)
Antisense Res Dev
, vol.1
, pp. 329
-
-
Ho, P.T.1
Ishiguro, K.2
Wickstrom, E.3
Sartorelli, A.C.4
-
268
-
-
0025834035
-
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element
-
Vickers T, Baker BF, Cook PD, Zounes M, Buckheit RW Jr, Germany J, Ecker DJ: Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res 19:3359, 1991
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3359
-
-
Vickers, T.1
Baker, B.F.2
Cook, P.D.3
Zounes, M.4
Buckheit Jr., R.W.5
Germany, J.6
Ecker, D.J.7
-
269
-
-
0026876215
-
Translation inhibition by phosphorothioate oligodeoxynucleotides in cell-free systems
-
Ghosh MK, Ghosh K, Cohen JS: Translation inhibition by phosphorothioate oligodeoxynucleotides in cell-free systems. Antisense Res Dev 2:111, 1992
-
(1992)
Antisense Res Dev
, vol.2
, pp. 111
-
-
Ghosh, M.K.1
Ghosh, K.2
Cohen, J.S.3
-
270
-
-
0026174653
-
Controls for antisense oligonucleotide experiments
-
Teaching editorial
-
Teaching editorial: Controls for antisense oligonucleotide experiments [editorial], Antisense Res Dev 1:187, 1991
-
(1991)
Antisense Res Dev
, vol.1
, pp. 187
-
-
|