Evaluation of polyplexes as gene transfer agents

Journal of Controlled Release

Volumn 73, Issue 2-3, 2001, Pages 401-416

  Gebhart, Catherine L ^a   Kabanov, Alexander V ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

Author keywords

DNA; Lipoplex; Polycation; Polyplex; Transgene expression

Indexed keywords

ASTRAMOL; CELLFECTIN; DENDRIMER; DMRIE C; DNA; EXGEN 500; LIPOFECTAMINE; LIPOFECTIN; P 123; POLOXAMER; POLY(N ETHYL 4 VINYL PYRIDINIUM BROMIDE); POLYAMIDOAMINE DENDRIMER; POLYCATION; POLYETHYLENEIMINE DERIVATIVE; POLYPROPYLENEIMINE DENDRIMER; REAGENT; SUPERFECT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL TYPE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL COUNT; CELL LINE; DNA; ELECTROPHORESIS; HUMANS; PARTICLE SIZE; POLYAMINES; TIME FACTORS; TRANSFECTION;

EID: 0035850212     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00357-1     Document Type: Article

References (28)

1. Nomenclature for synthetic gene delivery systems
2. Viral and non-viral vectors for cancer gene therapy
3. Taking polycation gene delivery systems from in vitro to in vivo
4. Cationic polymer based gene delivery systems
5. Nonviral gene therapy: The promise of genes as pharmaceutical products
6. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
7. Poly(ethylenimine) and its role in gene delivery
8. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
9. Nanoscopic structure of DNA condensed for gene delivery
10. Efficient transformation of mammalian cells using DNA interpolyelectrolyte complexes with carbon chain polycations
11. In vitro gene delivery by degraded polyamidoamine dendrimers
12. Polypropyleneimine dendrimers: Improved synthesis and characterization
13. Polyelectrolyte behavior of Astramol poly(propyleneimine) dendrimers
14. Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents
15. Solvation effects and reactivity of free pyridine residues in macromolecules of poly-4-vinylpyridine
16. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
17. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo - Polyethyleneimine
18. Increasing of transforming activity of plasmid DNA by incorporating it into an interpolyelectrolyte complex with a carbon chain polycation
19. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
20. The proton sponge: A trick to enter cells the viruses did not exploit
21. Characterization of commercially available and synthesized polyethylenimines for gene delivery
22. Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
23. DNA complexes with polycations for the delivery of genetic material into cells
24. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
25. Interpolyelectrolyte complexes for gene delivery: Polymer aspects of transfection activity
26. Transcriptional modulation of viral reporter gene constructs following induction of the cellular stress response
27. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus