-
3
-
-
0024328536
-
Altering the genome by homologous recombination
-
(1989)
Science
, vol.244
, pp. 1288-1292
-
-
Capecchi, M.R.1
-
6
-
-
0002509433
-
Overcoming the obstacles to gene therapy
-
(1997)
Sci Am
, vol.276
, Issue.6
, pp. 80-85
-
-
Friedmann, T.1
-
9
-
-
0031694735
-
Antisense technology; selection and delivery of optimally acting antisense oligonucleotides
-
(1998)
J Drug Targeting
, vol.5
, pp. 225-234
-
-
Akhtar, S.1
-
12
-
-
0021229867
-
Inhibition of thymidine kinase gene expression by anti-sense RNA; a molecular approach to genetic analysis
-
(1984)
Cell
, vol.36
, pp. 1007-1015
-
-
Izant, J.G.1
Weintraub, H.2
-
13
-
-
0021799874
-
Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA
-
(1985)
Science
, vol.229
, pp. 345-352
-
-
Izant, J.G.1
Weintraub, H.2
-
17
-
-
0029147628
-
Nonviral gene therapy; the promise of genes as pharmaceutical products
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1129-1144
-
-
Ledley, F.D.1
-
19
-
-
0031159393
-
Nonviral strategies for gene therapy
-
(1997)
Sci Am
, vol.276
, Issue.6
, pp. 86-90
-
-
Felgner, P.L.1
-
20
-
-
0025131814
-
Antisense strategies in cell and developmental biology
-
(1990)
J Cell Sci
, vol.97
, pp. 399-409
-
-
Colman, A.1
-
22
-
-
0001930040
-
Antisense oligonucleotides
-
Mol J.N.M., van der Krol A.R. (Eds.), Antisense nucleic acids and proteins. Fundamentals and applications, New York: Marcel Dekker
-
(1991)
, pp. 47-93
-
-
Cazenave, C.1
Helene, C.2
-
24
-
-
0002656848
-
Artificial regulation of gene expression by complementary oligonucleotides - an overview
-
Murray J.A.H. (Ed.), Antisense RNA and DNA, New York: Wiley-Liss
-
(1992)
, pp. 175-194
-
-
Toulme, J.J.1
-
28
-
-
0002651922
-
Antisense techniques; an overview
-
Murray J.A.H. (Ed.), Antisense RNA and DNA, New York: Wiley-Liss
-
(1992)
, pp. 1-49
-
-
Murray, J.A.H.1
Crockett, N.2
-
31
-
-
0002250564
-
Disrupting the flow of genetic information with antisense oligodeoxynucleotides; research and therapeutic applications
-
Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
-
(1995)
, pp. 1-15
-
-
Kregenow, D.1
Ratajczak, M.Z.2
Gewirtz, A.M.3
-
36
-
-
0002231265
-
Endocytosis; an overview
-
Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
-
(1998)
, pp. 71-88
-
-
Slepnev, V.I.1
De Camilli, P.2
-
38
-
-
0345570537
-
Characterization of oligonucleotide transport into living cells
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3474-3478
-
-
Loke, S.L.1
Stein, C.A.2
Zhang, X.H.3
Mori, K.4
Nakanishi, M.5
Subasinghe, C.6
Cohen, J.S.7
Neckers, L.M.8
-
39
-
-
0000071804
-
Pharmaceutical aspects of the biological stability and membrane transport characteristics of antisense oligonucleotides
-
Erickson R.P., Izant J.G. (Eds.), Gene regulation: biology of antisense RNA and DNA, New York: Raven Press
-
(1992)
, pp. 133-145
-
-
Akhtar, S.1
Shoji, Y.2
Juliano, R.L.3
-
42
-
-
0002442281
-
Cellular uptake, distribution and metabolism of phosphorothioate, phosphodiester, and methylphosphonate oligonucleotides
-
Crooke S.T., Lebleu B. (Eds.), Antisense research and applications, Boca Raton, FL: CRC Press
-
(1993)
, pp. 427-449
-
-
Crooke, R.M.1
-
43
-
-
0001014648
-
Cellular internalization of oligodeoxynucleotides
-
Crooke S.T., Lebleu B. (Eds.), Antisense research and applications, Boca Raton, FL: CRC Press
-
(1993)
, pp. 451-460
-
-
Neckers, L.M.1
-
44
-
-
0006537444
-
In vivo pharmacokinetics of oligonucleotides following administration by different routes
-
Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
-
(1995)
, pp. 71-83
-
-
Vlassov, V.V.1
Yakubov, L.A.2
Karamyshev, V.3
Pautova, L.4
Rykova, E.5
Nechaeva, M.6
-
54
-
-
0030001042
-
Electroporation of synthetic oligonucleotides; a novel technique for ex vivo bone marrow purging
-
(1996)
Blood
, vol.88
, pp. 731-741
-
-
Bergan, R.1
Hakim, F.2
Schwartz, G.N.3
Kyle, E.4
Cepada, R.5
Szabo, J.M.6
Fowler, D.7
Gress, R.8
Neckers, L.9
-
55
-
-
0027506794
-
Retrovirally transduced antisense sequences stably suppress P210 BCR-ABL expression and inhibit the proliferation of BCR/ABL-containing cell lines
-
(1993)
Blood
, vol.81
, pp. 502-509
-
-
Martiat, P.1
Lewalle, P.2
Taj, A.S.3
Philippe, M.4
Larondelle, Y.5
Vaerman, J.L.6
Wildmann, C.7
Goldman, J.M.8
Michaux, J.L.9
-
56
-
-
0027323303
-
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8474-8478
-
-
Morishita, R.1
Gibbons, G.H.2
Ellison, K.E.3
Nakajima, M.4
Zhang, L.5
Kaneda, Y.6
Ogihara, T.7
Dzau, V.J.8
-
57
-
-
0031584865
-
In vivo transfer efficiency of antisense oilgonucleotides into the myocardium using HVJ-liposome method
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 540-545
-
-
Aoki, M.1
Morishita, R.2
Higaki, J.3
Moriguchi, A.4
Kida, I.5
Hayashi, S.6
Matsushita, H.7
Kaneda, Y.8
Ogihara, T.9
-
61
-
-
0000013501
-
Liposomes as a delivery system for antisense and ribozyme compounds
-
Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
-
(1995)
, pp. 199-221
-
-
Thierry, A.R.1
Takle, G.B.2
-
62
-
-
0001556131
-
Intracellular delivery of oligonucleotides with cationic liposomes
-
Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
-
(1995)
, pp. 223-232
-
-
Bennett, C.F.1
-
63
-
-
0006587893
-
The delivery of oilgonucleotides using pH sensitive liposomes
-
Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
-
(1995)
, pp. 233-245
-
-
Ropert, C.1
Couvreur, P.2
Malvy, C.3
-
70
-
-
0031048990
-
Limitations of cationic liposomes for antisense oligonucleotide delivery in vivo
-
(1997)
J Liposome Res
, vol.7
, pp. 51-61
-
-
Litzinger, D.C.1
-
73
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
74
-
-
0023447252
-
Lipofectin; a highly efficient, lipid-mediated DNA-transfection procedure
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
Roman, R.4
Chan, H.W.5
Wenz, M.6
Northrop, J.P.7
Ringold, G.M.8
Danielsen, M.9
-
75
-
-
0006557227
-
Combination between different proteins and between proteins and yeast nucleic acid
-
(1946)
Biochem J
, vol.40
, pp. 677-687
-
-
Kleczkowski, A.1
-
77
-
-
0006589304
-
Studies on infection with Bacillus anthracis. VII. A comparison of the antibacterial effects of calf thymus histone and a quaternary ammonium cationic detergent on B. anthracis
-
(1947)
J Infect Dis
, vol.80
, pp. 145-153
-
-
Weissman, N.1
Graf, L.H.2
-
87
-
-
0014287606
-
The effect of polycations on the interaction of viral RNA with mammalian cells; studies on the infectivity of single- and double-stranded poliovirus RNA
-
(1968)
Virology
, vol.35
, pp. 9-17
-
-
Koch, G.1
Bishop, J.M.2
-
88
-
-
0006524824
-
Plaque assay for poliovirus and poliovirus specific RNAs
-
Habel K., Salzman N.P. (Eds.), Fundamental techniques in virology, New York: Academic Press
-
(1969)
, pp. 131-145
-
-
Bishop, J.M.1
Koch, G.2
-
89
-
-
0015093181
-
Influence of polycations on the interaction between poliovirus multistranded ribonucleic acid and HeLa cells
-
(1971)
J Virol
, vol.8
, pp. 35-40
-
-
Wentzky, P.1
Koch, G.2
-
100
-
-
0001408455
-
Histones and basic polyamino acids stimulate the uptake of albumin by tumor cells in culture
-
(1965)
Science
, vol.150
, pp. 501-503
-
-
Ryser, H.J.P.1
Hancock, R.2
-
101
-
-
0014217907
-
A membrane effect of basic polymers dependent on molecular size
-
(1967)
Nature
, vol.215
, pp. 934-936
-
-
Ryser, H.J.P.1
-
102
-
-
0014430496
-
Uptake of protein by mammalian cells; an underdeveloped area
-
(1968)
Science
, vol.159
, pp. 390-396
-
-
Ryser, H.J.P.1
-
106
-
-
0015966197
-
Uptake of polynucleotides by mammalian cells. XIV. Stimulation of the uptake of polynucleotides by poly(L-lysine)
-
(1974)
Biochim Biophys Acta
, vol.340
, pp. 323-333
-
-
Schell, P.L.1
-
108
-
-
0023651170
-
n analogues; synthesis and biological activity
-
(1987)
Biochemistry
, vol.26
, pp. 5172-5178
-
-
Bisbal, C.1
Silhol, M.2
Lemaitre, M.3
Bayard, B.4
Salehzada, T.5
Lebleu, B.6
Percee, T.D.7
Blackburn, M.G.8
-
113
-
-
0024421702
-
Inhibition of human immunodeficiency virus type 1-mediated cytopathic effects by poly(L-lysine)-conjugated synthetic antisense oligodeoxyribonucleotides
-
(1989)
J Gen Virol
, vol.70
, pp. 2673-2682
-
-
Stevenson, M.1
Iversen, P.L.2
-
116
-
-
0027756124
-
Oligonucleotide-poly-L-ornithine conjugates; binding to complementary DNA and RNA
-
(1993)
Antisense Res Dev
, vol.3
, pp. 265-275
-
-
Zhu, T.1
Wei, Z.2
Tung, C.H.3
Dickerhof, W.A.4
Breslauer, K.J.5
Georgopoulos, D.E.6
Leibowitz, M.J.7
Stein, S.8
-
118
-
-
0023212742
-
Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
-
(1987)
J Biol Chem
, vol.262
, pp. 4429-4432
-
-
Wu, G.Y.1
Wu, C.H.2
-
120
-
-
0026688793
-
Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
-
(1992)
J Biol Chem
, vol.267
, pp. 12436-12439
-
-
Wu, G.Y.1
Wu, C.H.2
-
128
-
-
0006550990
-
Terplex system for delivery of DNA and oligonucleotides
-
Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
-
(1998)
, pp. 149-166
-
-
Lentz, M.J.1
Kim, S.W.2
-
132
-
-
0033167315
-
Peptide-oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties
-
(1999)
Bioconjugate Chem
, vol.10
, pp. 598-606
-
-
Antopolsky, M.1
Azhayeva, E.2
Tengvall, U.3
Auriola, S.4
Jaaskelainen, I.5
Ronkko, S.6
Honkakoski, P.7
Urtti, A.8
Lonnberg, H.9
Azhayev, A.10
-
134
-
-
0000283833
-
Interpolyelectrolyte complexes for gene delivery; polymer aspects of transfection activity
-
Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
-
(1998)
, pp. 197-218
-
-
Kabanov, A.V.1
Szoka Jr, F.C.2
Seymour, L.W.3
-
142
-
-
0033427317
-
Polyethylenimine but not cationic lipid improves antisense activity of 3′-capped phosphodiester oligonucleotides
-
(1999)
Antisense Nucleic Acid Drug Dev
, vol.9
, pp. 515-525
-
-
Dheur, S.1
Dias, N.2
van Aerschot, A.3
Herdewijn, P.4
Bettinger, T.5
Remy, J.S.6
Helene, C.7
Saison-Behmoaras, E.T.8
-
145
-
-
0002663998
-
Cationic block copolymers as self-assembling vectors for gene delivery
-
Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
-
(1998)
, pp. 221-239
-
-
Seymour, L.W.1
Kataoka, K.2
Kabanov, A.V.3
-
164
-
-
15644381532
-
Poly(1-vinyl-2-pyrrolidinone) hydrogels as vitreous substitutes; a rheological study
-
(1998)
Polym Int
, vol.46
, pp. 183-195
-
-
Chirila, T.V.1
Hong, Y.2
-
168
-
-
0006581261
-
-
Lou X, Garrett KL, Rakoczy PE, Chirila TV. Synthetic hydrogels as carriers in antisense therapy: preliminary evaluation of an oligodeoxynucleotide covalent conjugate with a copolymer of 1-vinyl-2-pyrrolidinone and 2-hydroxyethyl methacrylate. J Biomater Appl 2001;15:in press.
-
-
-
-
170
-
-
0030919006
-
Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradable polymer microspheres
-
(1997)
Int J Pharm
, vol.151
, pp. 57-67
-
-
Akhtar, S.1
Lewis, K.J.2
-
171
-
-
0031689425
-
Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides; characterization of P(LA-GA) copolymer microspheres in vitro
-
(1998)
J Drug Targeting
, vol.5
, pp. 291-302
-
-
Lewis, K.J.1
Irwin, W.J.2
Akhtar, S.3
-
183
-
-
51249161487
-
Polyethylene glycol. A high-efficiency liquid phase (HELP) for the large-scale synthesis of the oligonucleotides
-
(1995)
Appl Biochem Biotechnol
, vol.54
, pp. 3-15
-
-
Bonora, G.M.1
-
197
-
-
0017317645
-
Polymers for the sustained release of proteins and other macromolecules
-
(1976)
Nature
, vol.263
, pp. 797-800
-
-
Langer, R.1
Folkman, J.2
-
202
-
-
0006559273
-
Polymer-cell surface interactions and drug targeting
-
Goldberg E.P. (Ed.), Targeted drugs, New York: Wiley
-
(1983)
, pp. 113-126
-
-
Pitha, J.1
-
204
-
-
0030738418
-
Local delivery of c-myb antisense oligonucleotides during balloon angioplasty
-
(1997)
Cathet Cardiovasc Diagn
, vol.41
, pp. 232-240
-
-
Azrin, M.A.1
Mitchel, J.F.2
Bow, L.M.3
Pedersen, C.A.4
Cartun, R.W.5
Aretz, T.H.6
Waters, D.D.7
McKay, R.G.8
|