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Volumn 23, Issue 2, 2002, Pages 321-342

The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides

Author keywords

Antisense oligodeoxynucleotides; Antisense strategy; Charged polymers; Drug delivery; Endocytosis; Neutral polymers

Indexed keywords

CELL MEMBRANES; MACROMOLECULES; OLIGOMERS;

EID: 0036131650     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(01)00125-9     Document Type: Review
Times cited : (126)

References (210)
  • 3
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • (1989) Science , vol.244 , pp. 1288-1292
    • Capecchi, M.R.1
  • 6
    • 0002509433 scopus 로고    scopus 로고
    • Overcoming the obstacles to gene therapy
    • (1997) Sci Am , vol.276 , Issue.6 , pp. 80-85
    • Friedmann, T.1
  • 9
    • 0031694735 scopus 로고    scopus 로고
    • Antisense technology; selection and delivery of optimally acting antisense oligonucleotides
    • (1998) J Drug Targeting , vol.5 , pp. 225-234
    • Akhtar, S.1
  • 12
    • 0021229867 scopus 로고
    • Inhibition of thymidine kinase gene expression by anti-sense RNA; a molecular approach to genetic analysis
    • (1984) Cell , vol.36 , pp. 1007-1015
    • Izant, J.G.1    Weintraub, H.2
  • 13
    • 0021799874 scopus 로고
    • Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA
    • (1985) Science , vol.229 , pp. 345-352
    • Izant, J.G.1    Weintraub, H.2
  • 17
    • 0029147628 scopus 로고
    • Nonviral gene therapy; the promise of genes as pharmaceutical products
    • (1995) Hum Gene Ther , vol.6 , pp. 1129-1144
    • Ledley, F.D.1
  • 19
    • 0031159393 scopus 로고    scopus 로고
    • Nonviral strategies for gene therapy
    • (1997) Sci Am , vol.276 , Issue.6 , pp. 86-90
    • Felgner, P.L.1
  • 20
    • 0025131814 scopus 로고
    • Antisense strategies in cell and developmental biology
    • (1990) J Cell Sci , vol.97 , pp. 399-409
    • Colman, A.1
  • 22
    • 0001930040 scopus 로고
    • Antisense oligonucleotides
    • Mol J.N.M., van der Krol A.R. (Eds.), Antisense nucleic acids and proteins. Fundamentals and applications, New York: Marcel Dekker
    • (1991) , pp. 47-93
    • Cazenave, C.1    Helene, C.2
  • 24
    • 0002656848 scopus 로고
    • Artificial regulation of gene expression by complementary oligonucleotides - an overview
    • Murray J.A.H. (Ed.), Antisense RNA and DNA, New York: Wiley-Liss
    • (1992) , pp. 175-194
    • Toulme, J.J.1
  • 28
    • 0002651922 scopus 로고
    • Antisense techniques; an overview
    • Murray J.A.H. (Ed.), Antisense RNA and DNA, New York: Wiley-Liss
    • (1992) , pp. 1-49
    • Murray, J.A.H.1    Crockett, N.2
  • 31
    • 0002250564 scopus 로고
    • Disrupting the flow of genetic information with antisense oligodeoxynucleotides; research and therapeutic applications
    • Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
    • (1995) , pp. 1-15
    • Kregenow, D.1    Ratajczak, M.Z.2    Gewirtz, A.M.3
  • 36
    • 0002231265 scopus 로고    scopus 로고
    • Endocytosis; an overview
    • Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
    • (1998) , pp. 71-88
    • Slepnev, V.I.1    De Camilli, P.2
  • 39
    • 0000071804 scopus 로고
    • Pharmaceutical aspects of the biological stability and membrane transport characteristics of antisense oligonucleotides
    • Erickson R.P., Izant J.G. (Eds.), Gene regulation: biology of antisense RNA and DNA, New York: Raven Press
    • (1992) , pp. 133-145
    • Akhtar, S.1    Shoji, Y.2    Juliano, R.L.3
  • 42
    • 0002442281 scopus 로고
    • Cellular uptake, distribution and metabolism of phosphorothioate, phosphodiester, and methylphosphonate oligonucleotides
    • Crooke S.T., Lebleu B. (Eds.), Antisense research and applications, Boca Raton, FL: CRC Press
    • (1993) , pp. 427-449
    • Crooke, R.M.1
  • 43
    • 0001014648 scopus 로고
    • Cellular internalization of oligodeoxynucleotides
    • Crooke S.T., Lebleu B. (Eds.), Antisense research and applications, Boca Raton, FL: CRC Press
    • (1993) , pp. 451-460
    • Neckers, L.M.1
  • 53
    • 0030813829 scopus 로고    scopus 로고
    • cAMP response element-binding protein in the amygdala is required for long-but not short-term conditioned taste aversion memory
    • (1997) J Neurosci , vol.17 , pp. 8443-8450
    • Lamprecht, R.1    Hazvi, S.2    Dudai, Y.3
  • 61
    • 0000013501 scopus 로고
    • Liposomes as a delivery system for antisense and ribozyme compounds
    • Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
    • (1995) , pp. 199-221
    • Thierry, A.R.1    Takle, G.B.2
  • 62
    • 0001556131 scopus 로고
    • Intracellular delivery of oligonucleotides with cationic liposomes
    • Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
    • (1995) , pp. 223-232
    • Bennett, C.F.1
  • 63
    • 0006587893 scopus 로고
    • The delivery of oilgonucleotides using pH sensitive liposomes
    • Akhtar S. (Ed.), Delivery strategies for antisense oligonucleotide therapeutics, Boca Raton, FL: CRC Press
    • (1995) , pp. 233-245
    • Ropert, C.1    Couvreur, P.2    Malvy, C.3
  • 70
  • 73
    • 0028019410 scopus 로고
    • Gene inhibition using antisense oligodeoxynucleotides
    • (1994) Nature , vol.372 , pp. 333-335
    • Wagner, R.W.1
  • 75
    • 0006557227 scopus 로고
    • Combination between different proteins and between proteins and yeast nucleic acid
    • (1946) Biochem J , vol.40 , pp. 677-687
    • Kleczkowski, A.1
  • 77
    • 0006589304 scopus 로고
    • Studies on infection with Bacillus anthracis. VII. A comparison of the antibacterial effects of calf thymus histone and a quaternary ammonium cationic detergent on B. anthracis
    • (1947) J Infect Dis , vol.80 , pp. 145-153
    • Weissman, N.1    Graf, L.H.2
  • 87
    • 0014287606 scopus 로고
    • The effect of polycations on the interaction of viral RNA with mammalian cells; studies on the infectivity of single- and double-stranded poliovirus RNA
    • (1968) Virology , vol.35 , pp. 9-17
    • Koch, G.1    Bishop, J.M.2
  • 88
    • 0006524824 scopus 로고
    • Plaque assay for poliovirus and poliovirus specific RNAs
    • Habel K., Salzman N.P. (Eds.), Fundamental techniques in virology, New York: Academic Press
    • (1969) , pp. 131-145
    • Bishop, J.M.1    Koch, G.2
  • 89
    • 0015093181 scopus 로고
    • Influence of polycations on the interaction between poliovirus multistranded ribonucleic acid and HeLa cells
    • (1971) J Virol , vol.8 , pp. 35-40
    • Wentzky, P.1    Koch, G.2
  • 100
    • 0001408455 scopus 로고
    • Histones and basic polyamino acids stimulate the uptake of albumin by tumor cells in culture
    • (1965) Science , vol.150 , pp. 501-503
    • Ryser, H.J.P.1    Hancock, R.2
  • 101
    • 0014217907 scopus 로고
    • A membrane effect of basic polymers dependent on molecular size
    • (1967) Nature , vol.215 , pp. 934-936
    • Ryser, H.J.P.1
  • 102
    • 0014430496 scopus 로고
    • Uptake of protein by mammalian cells; an underdeveloped area
    • (1968) Science , vol.159 , pp. 390-396
    • Ryser, H.J.P.1
  • 106
    • 0015966197 scopus 로고
    • Uptake of polynucleotides by mammalian cells. XIV. Stimulation of the uptake of polynucleotides by poly(L-lysine)
    • (1974) Biochim Biophys Acta , vol.340 , pp. 323-333
    • Schell, P.L.1
  • 113
    • 0024421702 scopus 로고
    • Inhibition of human immunodeficiency virus type 1-mediated cytopathic effects by poly(L-lysine)-conjugated synthetic antisense oligodeoxyribonucleotides
    • (1989) J Gen Virol , vol.70 , pp. 2673-2682
    • Stevenson, M.1    Iversen, P.L.2
  • 118
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • (1987) J Biol Chem , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 120
    • 0026688793 scopus 로고
    • Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
    • (1992) J Biol Chem , vol.267 , pp. 12436-12439
    • Wu, G.Y.1    Wu, C.H.2
  • 128
    • 0006550990 scopus 로고    scopus 로고
    • Terplex system for delivery of DNA and oligonucleotides
    • Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
    • (1998) , pp. 149-166
    • Lentz, M.J.1    Kim, S.W.2
  • 134
    • 0000283833 scopus 로고    scopus 로고
    • Interpolyelectrolyte complexes for gene delivery; polymer aspects of transfection activity
    • Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
    • (1998) , pp. 197-218
    • Kabanov, A.V.1    Szoka Jr, F.C.2    Seymour, L.W.3
  • 145
    • 0002663998 scopus 로고    scopus 로고
    • Cationic block copolymers as self-assembling vectors for gene delivery
    • Kabanov A.V., Felgner P.L., Seymour L.W. (Eds.), Self-assembling complexes for gene delivery, Chichester: Wiley
    • (1998) , pp. 221-239
    • Seymour, L.W.1    Kataoka, K.2    Kabanov, A.V.3
  • 164
    • 15644381532 scopus 로고    scopus 로고
    • Poly(1-vinyl-2-pyrrolidinone) hydrogels as vitreous substitutes; a rheological study
    • (1998) Polym Int , vol.46 , pp. 183-195
    • Chirila, T.V.1    Hong, Y.2
  • 168
    • 0006581261 scopus 로고    scopus 로고
    • Lou X, Garrett KL, Rakoczy PE, Chirila TV. Synthetic hydrogels as carriers in antisense therapy: preliminary evaluation of an oligodeoxynucleotide covalent conjugate with a copolymer of 1-vinyl-2-pyrrolidinone and 2-hydroxyethyl methacrylate. J Biomater Appl 2001;15:in press.
  • 170
    • 0030919006 scopus 로고    scopus 로고
    • Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradable polymer microspheres
    • (1997) Int J Pharm , vol.151 , pp. 57-67
    • Akhtar, S.1    Lewis, K.J.2
  • 171
    • 0031689425 scopus 로고    scopus 로고
    • Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides; characterization of P(LA-GA) copolymer microspheres in vitro
    • (1998) J Drug Targeting , vol.5 , pp. 291-302
    • Lewis, K.J.1    Irwin, W.J.2    Akhtar, S.3
  • 176
  • 183
    • 51249161487 scopus 로고
    • Polyethylene glycol. A high-efficiency liquid phase (HELP) for the large-scale synthesis of the oligonucleotides
    • (1995) Appl Biochem Biotechnol , vol.54 , pp. 3-15
    • Bonora, G.M.1
  • 186
  • 197
    • 0017317645 scopus 로고
    • Polymers for the sustained release of proteins and other macromolecules
    • (1976) Nature , vol.263 , pp. 797-800
    • Langer, R.1    Folkman, J.2
  • 202
    • 0006559273 scopus 로고
    • Polymer-cell surface interactions and drug targeting
    • Goldberg E.P. (Ed.), Targeted drugs, New York: Wiley
    • (1983) , pp. 113-126
    • Pitha, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.