-
2
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida A. R., Legrand N., Papiernik M. and Freitas A. A. (2002): Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J. Immunol., 169, 4850-4860.
-
(2002)
J. Immunol.
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
3
-
-
0035284804
-
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
-
Annacker O., Pimenta-Araujo R., Burlen-Defranoux O., Barbosa T. C., Cumano A. and Bandeira A. (2001): CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J. Immunol., 166, 3008-3018.
-
(2001)
J. Immunol.
, vol.166
, pp. 3008-3018
-
-
Annacker, O.1
Pimenta-Araujo, R.2
Burlen-Defranoux, O.3
Barbosa, T.C.4
Cumano, A.5
Bandeira, A.6
-
4
-
-
0037026003
-
Phenotype, localization, and mechanism of suppression of CD4+ CD25+ human thymocytes
-
Annunziato F., Cosmi L., Liotta F., Lazzeri E., Manetti R., Vanini V., Romagnani P., Maggi E. and Romagnani S. (2002): Phenotype, localization, and mechanism of suppression of CD4+ CD25+ human thymocytes. J. Exp. Med., 196, 379-387.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 379-387
-
-
Annunziato, F.1
Cosmi, L.2
Liotta, F.3
Lazzeri, E.4
Manetti, R.5
Vanini, V.6
Romagnani, P.7
Maggi, E.8
Romagnani, S.9
-
5
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou I., Sarukhan A., Klein L. and von Boehmer H. (2002): Origin of regulatory T cells with known specificity for antigen. Nat. Immunol., 3, 756-763.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
Von Boehmer, H.4
-
6
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I. and von Boehmer H. (2004): In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med., 199, 1401-1408.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
7
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano M., Toda M., Sakaguchi N. and Sakaguchi S. (1996): Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med., 184, 387-396.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
8
-
-
0038783387
-
Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: Control by CD4+ regulatory T cells and IL-10
-
Asseman C., Read S. and Powrie F. (2003): Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10. J. Immunol., 171, 971-978.
-
(2003)
J. Immunol.
, vol.171
, pp. 971-978
-
-
Asseman, C.1
Read, S.2
Powrie, F.3
-
9
-
-
0035413350
-
CD4+CD25high regulatory cells in human peripheral blood
-
Baecher-Allan C., Brown J. A., Freeman G. J. and Hafler D. A. (2001): CD4+CD25high regulatory cells in human peripheral blood. J. Immunol., 167, 1245-1253.
-
(2001)
J. Immunol.
, vol.167
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
10
-
-
0141762495
-
A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis
-
Banz A., Peixoto A., Pontoux C., Cordier C., Rocha B. and Papiernik M. (2003): A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis. Eur. J. Immunol., 33, 2419-2428.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 2419-2428
-
-
Banz, A.1
Peixoto, A.2
Pontoux, C.3
Cordier, C.4
Rocha, B.5
Papiernik, M.6
-
11
-
-
0037450727
-
T cell regulation as a side effect of homeostasis and competition
-
Barthlott T., Kassiotis G. and Stockinger B. (2003): T cell regulation as a side effect of homeostasis and competition. J. Exp. Med., 197, 451-460.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 451-460
-
-
Barthlott, T.1
Kassiotis, G.2
Stockinger, B.3
-
12
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M., Bluestone J. A., Barriot S., Megret J., Bach J. F. and Chatenoud L. (2003): TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat. Med., 9, 1202-1208.
-
(2003)
Nat. Med.
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
13
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid Y., Piccirillo C. A., Mendez S., Shevach E. M. and Sacks D. L. (2002): CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature, 420, 502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
14
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett C. L., Christie J., Ramsdell F., Brunkow M. E., Ferguson P. J., Whitesell L., Kelly T. E., Saulsbury F. T., Chance P. F. and Ochs H. D. (2001): The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet., 27, 20-21.
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
Kelly, T.E.7
Saulsbury, F.T.8
Chance, P.F.9
Ochs, H.D.10
-
15
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
Bluestone J. A. and Abbas A. K. (2003): Natural versus adaptive regulatory T cells. Nat. Rev. Immunol., 3, 253-257.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 253-257
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
16
-
-
5144222918
-
Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells
-
USA
-
Bluestone J. A. and Tang Q. (2004): Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells. Proc. Natl. Acad. Sci. USA, 101 (suppl. 2), 14622-14626.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, Issue.2 SUPPL.
, pp. 14622-14626
-
-
Bluestone, J.A.1
Tang, Q.2
-
17
-
-
0035198252
-
B cells and professional APCs recruit regulatory T cells via CCL4
-
Bystry R. S., Aluvihare V., Welch K. A., Kallikourdis M. and Betz A. G. (2001): B cells and professional APCs recruit regulatory T cells via CCL4. Nat. Immunol., 2, 1126-1132.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1126-1132
-
-
Bystry, R.S.1
Aluvihare, V.2
Welch, K.A.3
Kallikourdis, M.4
Betz, A.G.5
-
18
-
-
15244361536
-
CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
-
Cao D., Vollenhoven R., Klareskog L., Trollmo C. and Malmstrom V. (2004): CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease. Arthritis Res. Ther., 6, R335-346.
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Cao, D.1
Vollenhoven, R.2
Klareskog, L.3
Trollmo, C.4
Malmstrom, V.5
-
19
-
-
0034077559
-
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
Cederbom L., Hall H. and Ivars F. (2000): CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur. J. Immunol., 30, 1538-1543.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
20
-
-
0036686399
-
CD4+CD25+ T cells as immunoregulatory T cells in vitro
-
Chai J. G., Tsang J. Y., Lechler R., Simpson E., Dyson J. and Scott D. (2002): CD4+CD25+ T cells as immunoregulatory T cells in vitro. Eur. J. Immunol., 32, 2365-2375.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2365-2375
-
-
Chai, J.G.1
Tsang, J.Y.2
Lechler, R.3
Simpson, E.4
Dyson, J.5
Scott, D.6
-
21
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W., Jin W., Hardegen N., Lei K.-j., Li L., Marinos N., McGrady G. and Wahl S. M. (2003): Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med., 198, 1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.-J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
22
-
-
0032538819
-
Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
-
Chen W., Jin W. and Wahl S. M. (1998): Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells. J. Exp. Med., 188, 1849-1857.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1849-1857
-
-
Chen, W.1
Jin, W.2
Wahl, S.M.3
-
23
-
-
2442425262
-
Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
-
Cobbold S. P., Castejon R., Adams E., Zelenika D., Graca L., Humm S. and Waldmann H. (2004): Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol., 172, 6003-6010.
-
(2004)
J. Immunol.
, vol.172
, pp. 6003-6010
-
-
Cobbold, S.P.1
Castejon, R.2
Adams, E.3
Zelenika, D.4
Graca, L.5
Humm, S.6
Waldmann, H.7
-
24
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel T. J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., Evdemon-Hogan M., Conejo-Garcia J. R., Zhang L., Burow M., Zhu Y., Wei S., Kryczek I., Daniel B., Gordon A., Myers L., Lackner A., Disis M. L., Knutson K. L., Chen L. and Zou W. (2004): Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med., 10, 942-949.
-
(2004)
Nat. Med.
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
Zhu, Y.11
Wei, S.12
Kryczek, I.13
Daniel, B.14
Gordon, A.15
Myers, L.16
Lackner, A.17
Disis, M.L.18
Knutson, K.L.19
Chen, L.20
Zou, W.21
more..
-
25
-
-
2442618129
-
CD4+CD25(bright) regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis
-
de Kleer I. M., Wedderburn L. R., Taams L. S., Patel A., Varsani H., Klein M., de Jager W., Pugayung G., Giannoni F., Rijkers G., Albani S., Kuis W. and Prakken B. (2004): CD4+CD25(bright) regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J. Immunol., 172, 6435-6443.
-
(2004)
J. Immunol.
, vol.172
, pp. 6435-6443
-
-
De Kleer, I.M.1
Wedderburn, L.R.2
Taams, L.S.3
Patel, A.4
Varsani, H.5
Klein, M.6
De Jager, W.7
Pugayung, G.8
Giannoni, F.9
Rijkers, G.10
Albani, S.11
Kuis, W.12
Prakken, B.13
-
26
-
-
4644369302
-
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
-
de la Rosa M., Rutz S., Dorninger H. and Scheffold A. (2004): Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur. J. Immunol., 34, 2480-2488.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2480-2488
-
-
De La Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
27
-
-
0037099733
-
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
-
corrected
-
Dieckmann D., Bruett C. H., Ploettner H., Lutz M. B. and Schuler G. (2002): Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J. Exp. Med., 196, 247-253.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 247-253
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
28
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
-
Ehrenstein M. R., Evans J. G., Singh A., Moore S., Warnes G., Isenberg D. A. and Mauri C. (2004): Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J. Exp. Med., 200, 277-285.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
Moore, S.4
Warnes, G.5
Isenberg, D.A.6
Mauri, C.7
-
29
-
-
0035887614
-
CD4+CD25+ T cells facilitate the induction of T cell anergy
-
Ermann J., Szanya V., Ford G. S., Paragas V., Fathman C. G. and Lejon K. (2001): CD4+CD25+ T cells facilitate the induction of T cell anergy. J. Immunol., 167, 4271-4275.
-
(2001)
J. Immunol.
, vol.167
, pp. 4271-4275
-
-
Ermann, J.1
Szanya, V.2
Ford, G.S.3
Paragas, V.4
Fathman, C.G.5
Lejon, K.6
-
30
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino F., Grohmann U., Hwang K. W., Orabona C., Vacca C., Bianchi R., Belladonna M. L., Fioretti M. C., Alegre M. L. and Puccetti P. (2003): Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol., 4, 1206-1212.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
Grohmann, U.2
Hwang, K.W.3
Orabona, C.4
Vacca, C.5
Bianchi, R.6
Belladonna, M.L.7
Fioretti, M.C.8
Alegre, M.L.9
Puccetti, P.10
-
31
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini M. C., Becker C., Monteleone G., Pallone F., Galle P. R. and Neurath M. F. (2004): Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol., 172, 5149-5153.
-
(2004)
J. Immunol.
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
32
-
-
0041884743
-
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state
-
Fisson S., Darrasse-Jeze G., Litvinova E., Septier F., Klatzmann D., Liblau R. and Salomon B. L. (2003): Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J. Exp. Med., 198, 737-746.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 737-746
-
-
Fisson, S.1
Darrasse-Jeze, G.2
Litvinova, E.3
Septier, F.4
Klatzmann, D.5
Liblau, R.6
Salomon, B.L.7
-
33
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot J. D., Gavin M. A. and Rudensky A. Y. (2003): Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol., 4, 330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
34
-
-
0242412365
-
A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation
-
Foussat A., Cottrez F., Brun V., Fournier N., Breittmayer J.-P. and Groux H. (2003): A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation. J. Immunol., 171, 5018-5026.
-
(2003)
J. Immunol.
, vol.171
, pp. 5018-5026
-
-
Foussat, A.1
Cottrez, F.2
Brun, V.3
Fournier, N.4
Breittmayer, J.-P.5
Groux, H.6
-
35
-
-
20144370643
-
The role of regulatory T cells antigen-induced arthritis: Aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells
-
Frey O., Petrow P. K., Gajda M., Siegmund K., Huehn J., Scheffold A., Hamann A., Radbruch A. and Brauer R. (2005): The role of regulatory T cells antigen-induced arthritis: Aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells. Arthritis Res. Ther., 7, R291-R301.
-
(2005)
Arthritis Res. Ther.
, vol.7
-
-
Frey, O.1
Petrow, P.K.2
Gajda, M.3
Siegmund, K.4
Huehn, J.5
Scheffold, A.6
Hamann, A.7
Radbruch, A.8
Brauer, R.9
-
36
-
-
0037120053
-
Interleukin 2 signaling is required for CD4(+) regulatory T cell function
-
Furtado G. C., Curotto de Lafaille M. A., Kutchukhidze N. and Lafaille J. J. (2002): Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J. Exp. Med., 196, 851-857.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 851-857
-
-
Furtado, G.C.1
Curotto De Lafaille, M.A.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
37
-
-
0015172562
-
Infectious immunological tolerance
-
Gershon R. and Kondo K. (1971): Infectious immunological tolerance. Immunology, 21, 903-914.
-
(1971)
Immunology
, vol.21
, pp. 903-914
-
-
Gershon, R.1
Kondo, K.2
-
38
-
-
0036858838
-
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens
-
Golgher D., Jones E., Powrie F., Elliott T. and Gallimore A. (2002): Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur. J. Immunol., 32, 3267-3275.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3267-3275
-
-
Golgher, D.1
Jones, E.2
Powrie, F.3
Elliott, T.4
Gallimore, A.5
-
39
-
-
0037124359
-
Identification of regulatory T cells in tolerated allografts
-
Graca L., Cobbold S. P. and Waldmann H. (2002): Identification of regulatory T cells in tolerated allografts. J. Exp. Med., 195, 1641-1646.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1641-1646
-
-
Graca, L.1
Cobbold, S.P.2
Waldmann, H.3
-
40
-
-
0141703239
-
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
-
USA
-
Green E. A., Gorelik L., McGregor C. M., Tran E. H. and Flavell R. A. (2003): CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc. Natl. Acad. Sci. USA, 100, 10878-10883.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 10878-10883
-
-
Green, E.A.1
Gorelik, L.2
McGregor, C.M.3
Tran, E.H.4
Flavell, R.A.5
-
41
-
-
2942692037
-
CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
-
Herman A. E., Freeman G. J., Mathis D. and Benoist C. (2004): CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J. Exp. Med., 199, 1479-1489.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1479-1489
-
-
Herman, A.E.1
Freeman, G.J.2
Mathis, D.3
Benoist, C.4
-
42
-
-
3242801352
-
Large-scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells
-
Hoffmann P., Eder R., Kunz-Schughart L. A., Andreesen R. and Edinger M. (2004): Large-scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells. Blood, 104, 895-903.
-
(2004)
Blood
, vol.104
, pp. 895-903
-
-
Hoffmann, P.1
Eder, R.2
Kunz-Schughart, L.A.3
Andreesen, R.4
Edinger, M.5
-
43
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S., Nomura T. and Sakaguchi S. (2003): Control of regulatory T cell development by the transcription factor Foxp3. Science, 299, 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
44
-
-
4143066714
-
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
-
Hsieh C. S., Liang Y., Tyznik A. J., Self S. G., Liggitt D. and Rudensky A. Y. (2004): Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity, 21, 267-277.
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
Liang, Y.2
Tyznik, A.J.3
Self, S.G.4
Liggitt, D.5
Rudensky, A.Y.6
-
45
-
-
10744221289
-
Developmental stage, phenotype and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells
-
Huehn J., Siegmund K., Lehmann J., Siewert C., Haubold U., Feuerer M., Debes G., Lauber J., Frey O., Przybylski G., de la Rosa M., Schmidt C., Brauer R., Buer J., Scheffold A. and Hamann A. (2004): Developmental stage, phenotype and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells. J. Exp. Med., 199, 303-313.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 303-313
-
-
Huehn, J.1
Siegmund, K.2
Lehmann, J.3
Siewert, C.4
Haubold, U.5
Feuerer, M.6
Debes, G.7
Lauber, J.8
Frey, O.9
Przybylski, G.10
De La Rosa, M.11
Schmidt, C.12
Brauer, R.13
Buer, J.14
Scheffold, A.15
Hamann, A.16
-
46
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh M., Takahashi T., Sakaguchi N., Kuniyasu Y., Shimizu J., Otsuka F. and Sakaguchi S. (1999): Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol., 162, 5317-5326.
-
(1999)
J. Immunol.
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
Kuniyasu, Y.4
Shimizu, J.5
Otsuka, F.6
Sakaguchi, S.7
-
47
-
-
3242736641
-
Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
-
Jones E., Dahm-Vicker M., Simon A. K., Green A., Powrie F., Cerundolo V. and Gallimore A. (2002): Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immun., 2, 1.
-
(2002)
Cancer Immun.
, vol.2
, pp. 1
-
-
Jones, E.1
Dahm-Vicker, M.2
Simon, A.K.3
Green, A.4
Powrie, F.5
Cerundolo, V.6
Gallimore, A.7
-
48
-
-
0037099719
-
Infectious tolerance: Human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells
-
Jonuleit H., Schmitt E., Kakirman H., Stassen M., Knop J. and Enk A. H. (2002): Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J. Exp. Med., 196, 255-260.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 255-260
-
-
Jonuleit, H.1
Schmitt, E.2
Kakirman, H.3
Stassen, M.4
Knop, J.5
Enk, A.H.6
-
49
-
-
0035806290
-
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
-
Jonuleit H., Schmitt E., Stassen M., Tuettenberg A., Knop J. and Enk A. H. (2001): Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med., 193, 1285-1294.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1285-1294
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
50
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan M. S., Boesteanu A., Reed A. J., Petrone A. L., Holenbeck A. E., Lerman M. A., Naji A. and Caton A. J. (2001): Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol., 2, 301-306.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
51
-
-
1642454708
-
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
-
Karim M., Kingsley C. I., Bushell A. R., Sawitzki B. S. and Wood K. J. (2004): Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process. J. Immunol., 172, 923-928.
-
(2004)
J. Immunol.
, vol.172
, pp. 923-928
-
-
Karim, M.1
Kingsley, C.I.2
Bushell, A.R.3
Sawitzki, B.S.4
Wood, K.J.5
-
52
-
-
0036568942
-
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
Kawahata K., Misaki Y., Yamauchi M., Tsunekawa S., Setoguchi K., Miyazaki J. and Yamamoto K. (2002): Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol., 168, 4399-4405.
-
(2002)
J. Immunol.
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
Misaki, Y.2
Yamauchi, M.3
Tsunekawa, S.4
Setoguchi, K.5
Miyazaki, J.6
Yamamoto, K.7
-
53
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri R., Cox T., Yasayko S. A. and Ramsdell F. (2003): An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol., 4, 337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
54
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King C., Ilic A, Koelsch K. and Sarvetnick N. (2004): Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell, 117, 265-277.
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
55
-
-
0036467522
-
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
Kingsley C. I., Karim M., Bushell A. R. and Wood K. J. (2002): CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol., 168, 1080-1086.
-
(2002)
J. Immunol.
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
56
-
-
0041806547
-
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
-
USA
-
Klein L., Khazaie K. and von Boehmer H. (2003): In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc. Natl. Acad. Sci. USA, 100, 8886-8891.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 8886-8891
-
-
Klein, L.1
Khazaie, K.2
Von Boehmer, H.3
-
57
-
-
0033853625
-
Naturally anergic and suppressive CD25+CD4+ T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
-
Kuniyasu Y., Takahashi T., Itoh M., Shimizu J., Toda G. and Sakaguchi S. (2000): Naturally anergic and suppressive CD25+CD4+ T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int. Immunol., 12, 1145-1155.
-
(2000)
Int. Immunol.
, vol.12
, pp. 1145-1155
-
-
Kuniyasu, Y.1
Takahashi, T.2
Itoh, M.3
Shimizu, J.4
Toda, G.5
Sakaguchi, S.6
-
58
-
-
2442641572
-
Promotion of allograft survival by CD4+CD25+ regulatory T cells: Evidence for in vivo inhibition of effector cell proliferation
-
Lee M. K. 4th, Moore D. J., Jarrett B. P., Lian M. M., Deng S., Huang X., Markmann J. W., Chiaccio M., Barker C. F., Caton A. J. and Markmann J. F. (2004): Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation. J. Immunol., 172, 6539-6544.
-
(2004)
J. Immunol.
, vol.172
, pp. 6539-6544
-
-
Lee IV, M.K.1
Moore, D.J.2
Jarrett, B.P.3
Lian, M.M.4
Deng, S.5
Huang, X.6
Markmann, J.W.7
Chiaccio, M.8
Barker, C.F.9
Caton, A.J.10
Markmann, J.F.11
-
59
-
-
0036791004
-
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25-regulatory T cells
-
USA
-
Lehmann J., Huehn J., de la Rosa M., Maszyna F., Kretschmer U., Krenn V., Brunner M., Scheffold A. and Hamann A. (2002): Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25-regulatory T cells. Proc. Natl. Acad. Sci. USA, 99, 13031-13036.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 13031-13036
-
-
Lehmann, J.1
Huehn, J.2
De La Rosa, M.3
Maszyna, F.4
Kretschmer, U.5
Krenn, V.6
Brunner, M.7
Scheffold, A.8
Hamann, A.9
-
60
-
-
0035806323
-
Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings M. K., Sangregorio R. and Roncarolo M. G. (2001): Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med., 193, 1295-1302.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
61
-
-
0037352740
-
Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist
-
Lin C. H. and Hunig T. (2003): Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist. Eur. J. Immunol., 33, 626-638.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 626-638
-
-
Lin, C.H.1
Hunig, T.2
-
62
-
-
0242580070
-
CD4+CD25+ regulatory T cells cure murine colitis: The role of IL-10, TGF-beta, and CTLA4
-
Liu H., Hu B., Xu D. and Liew F. Y. (2003): CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J. Immunol., 171, 5012-5017.
-
(2003)
J. Immunol.
, vol.171
, pp. 5012-5017
-
-
Liu, H.1
Hu, B.2
Xu, D.3
Liew, F.Y.4
-
63
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
Liyanage U. K., Moore T. T., Joo H. G., Tanaka Y., Herrmann V., Doherty G., Drebin J. A., Strasberg S. M., Eberlein T. J., Goedegebuure P. S. and Linehan D. C. (2002): Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol., 169, 2756-2761.
-
(2002)
J. Immunol.
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
Moore, T.T.2
Joo, H.G.3
Tanaka, Y.4
Herrmann, V.5
Doherty, G.6
Drebin, J.A.7
Strasberg, S.M.8
Eberlein, T.J.9
Goedegebuure, P.S.10
Linehan, D.C.11
-
64
-
-
0038792101
-
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells
-
Mahnke K., Qian Y., Knop J. and Enk A. H. (2003): Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood, 101, 4862-4869.
-
(2003)
Blood
, vol.101
, pp. 4862-4869
-
-
Mahnke, K.1
Qian, Y.2
Knop, J.3
Enk, A.H.4
-
65
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
Maloy K. J., Salaun L., Cahill R., Dougan G., Saunders N. J. and Powrie F. (2003): CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med., 197, 111-119.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
Salaun, L.2
Cahill, R.3
Dougan, G.4
Saunders, N.J.5
Powrie, F.6
-
66
-
-
1542619331
-
Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo
-
Martin B., Banz A, Bienvenu B., Cordier C., Dautigny N., Becourt C. and Lucas B. (2004): Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo. J. Immunol., 172, 3391-3398.
-
(2004)
J. Immunol.
, vol.172
, pp. 3391-3398
-
-
Martin, B.1
Banz, A.2
Bienvenu, B.3
Cordier, C.4
Dautigny, N.5
Becourt, C.6
Lucas, B.7
-
67
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh R. S., Whitters M. J., Piccirillo C. A., Young D. A, Shevach E. M., Collins M. and Byrne M. C. (2002): CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid- induced TNF receptor. Immunity, 16, 311-323.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
Young, D.A.4
Shevach, E.M.5
Collins, M.6
Byrne, M.C.7
-
68
-
-
1842581857
-
Cutting edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
-
Misra N., Bayry J., Lacroix-Desmazes S., Kazatchkine M. D. and Kaveri S. V. (2004): Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J. Immunol., 172, 4676-4680.
-
(2004)
J. Immunol.
, vol.172
, pp. 4676-4680
-
-
Misra, N.1
Bayry, J.2
Lacroix-Desmazes, S.3
Kazatchkine, M.D.4
Kaveri, S.V.5
-
69
-
-
1642364976
-
Mini-review: Regulatory T cells and infection: suppression revisited
-
Mittrucker H. W. and Kaufmann S. H. (2004): Mini-review: Regulatory T cells and infection: suppression revisited. Eur. J. Immunol., 34, 306-312.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 306-312
-
-
Mittrucker, H.W.1
Kaufmann, S.H.2
-
70
-
-
0038666539
-
CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis
-
Morgan M. E., Sutmuller R. P., Witteveen H. J., van Duivenvoorde L. M., Zanelli E., Melief C. J., Snijders A., Offringa R., de Vries R. R. and Toes R. E. (2003): CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis. Arthritis Rheum., 48, 1452-1460.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 1452-1460
-
-
Morgan, M.E.1
Sutmuller, R.P.2
Witteveen, H.J.3
Van Duivenvoorde, L.M.4
Zanelli, E.5
Melief, C.J.6
Snijders, A.7
Offringa, R.8
De Vries, R.R.9
Toes, R.E.10
-
71
-
-
0037446531
-
Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells
-
Mottet C., Uhlig H. H. and Powrie F. (2003): Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J. Immunol., 170, 3939-3943.
-
(2003)
J. Immunol.
, vol.170
, pp. 3939-3943
-
-
Mottet, C.1
Uhlig, H.H.2
Powrie, F.3
-
72
-
-
1642577126
-
TGF-beta1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
-
Nakamura K., Kitani A., Fuss I., Pedersen A., Harada N., Nawata H. and Strober W. (2004): TGF-beta1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J. Immunol., 172, 834-842.
-
(2004)
J. Immunol.
, vol.172
, pp. 834-842
-
-
Nakamura, K.1
Kitani, A.2
Fuss, I.3
Pedersen, A.4
Harada, N.5
Nawata, H.6
Strober, W.7
-
73
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura K., Kitani A. and Strober W. (2001): Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med., 194, 629-644.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
74
-
-
0033168037
-
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
-
Onizuka S., Tawara I., Shimizu J., Sakaguchi S., Fujita T. and Nakayama E. (1999): Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res., 59, 3128-3133.
-
(1999)
Cancer Res.
, vol.59
, pp. 3128-3133
-
-
Onizuka, S.1
Tawara, I.2
Shimizu, J.3
Sakaguchi, S.4
Fujita, T.5
Nakayama, E.6
-
75
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare C. and Medzhitov R. (2003): Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science, 299, 1033-1036.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
76
-
-
1842480959
-
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
-
USA
-
Peng Y., Laouar Y., Li M. O., Green E. A. and Flavell R. A. (2004): TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc. Natl. Acad. Sci. USA, 101, 4572-4577.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 4572-4577
-
-
Peng, Y.1
Laouar, Y.2
Li, M.O.3
Green, E.A.4
Flavell, R.A.5
-
77
-
-
0037099613
-
CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
Piccirillo C. A., Letterio J. J., Thornton A. M., McHugh R. S., Mamura M., Mizuhara H. and Shevach E. M. (2002): CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J. Exp. Med., 196, 237-246.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
78
-
-
0035421654
-
Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
-
Piccirillo C. A. and Shevach E. M. (2001): Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J. Immunol., 167, 1137-1140.
-
(2001)
J. Immunol.
, vol.167
, pp. 1137-1140
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
79
-
-
1842607712
-
Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs
-
Putheti P., Pettersson A., Soderstrom M., Link H. and Huang Y. M. (2004): Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs. J. Clin. Immunol., 24, 155-161.
-
(2004)
J. Clin. Immunol.
, vol.24
, pp. 155-161
-
-
Putheti, P.1
Pettersson, A.2
Soderstrom, M.3
Link, H.4
Huang, Y.M.5
-
80
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S., Malmstrom V. and Powrie F. (2000): Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med., 192, 295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
81
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. (2004): Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol., 22, 531-562.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
82
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S., Sakaguchi N., Asano M., Itoh M. and Toda M. (1995): Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol., 155, 1151-1164.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
83
-
-
4344657757
-
CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
-
Sarween N., Chodos A., Raykundalia C., Khan M., Abbas A.K. and Walker L. S. (2004): CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J. Immunol., 173, 2942-2951.
-
(2004)
J. Immunol.
, vol.173
, pp. 2942-2951
-
-
Sarween, N.1
Chodos, A.2
Raykundalia, C.3
Khan, M.4
Abbas, A.K.5
Walker, L.S.6
-
84
-
-
4544357207
-
TGFbeta regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo
-
Schramm C., Huber S., Protschka M., Czochra P., Burg J., Schmitt E., Lohse A. W., Galle P. R. and Blessing M. (2004): TGFbeta regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo. Int. Immunol., 16, 1241-1249.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1241-1249
-
-
Schramm, C.1
Huber, S.2
Protschka, M.3
Czochra, P.4
Burg, J.5
Schmitt, E.6
Lohse, A.W.7
Galle, P.R.8
Blessing, M.9
-
85
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
Schubert L. A., Jeffery E., Zhang Y., Ramsdell F. and Ziegler S. F. (2001): Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem., 276, 37672-37679.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
86
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
Shimizu J., Yamazaki S. and Sakaguchi S. (1999): Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol., 163, 5211-5218.
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
87
-
-
0036170938
-
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu J., Yamazaki S., Takahashi T., Ishida Y. and Sakaguchi S. (2002): Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol., 3, 135-142.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
88
-
-
0034665514
-
CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations
-
Stephens L. A. and Mason D. (2000): CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations. J. Immunol., 165, 3105-3110.
-
(2000)
J. Immunol.
, vol.165
, pp. 3105-3110
-
-
Stephens, L.A.1
Mason, D.2
-
89
-
-
0035054606
-
Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro
-
Stephens L. A., Mottet C., Mason D. and Powrie F. (2001): Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur. J. Immunol., 31, 1247-1254.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 1247-1254
-
-
Stephens, L.A.1
Mottet, C.2
Mason, D.3
Powrie, F.4
-
90
-
-
0031939403
-
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
-
Suri-Payer E., Amar A. Z., Thornton A. M. and Shevach E. M. (1998): CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol., 160, 1212-1218.
-
(1998)
J. Immunol.
, vol.160
, pp. 1212-1218
-
-
Suri-Payer, E.1
Amar, A.Z.2
Thornton, A.M.3
Shevach, E.M.4
-
91
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer E. and Cantor H. (2001): Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J. Autoimmun., 16, 115-123.
-
(2001)
J. Autoimmun.
, vol.16
, pp. 115-123
-
-
Suri-Payer, E.1
Cantor, H.2
-
92
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller R. P., van Duivenvoorde L. M., van Elsas A., Schumacher T. N., Wildenberg M. E., Allison J. P., Toes R. E., Offringa R. and Melief C. J. (2001): Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med., 194, 823-832.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
Van Duivenvoorde, L.M.2
Van Elsas, A.3
Schumacher, T.N.4
Wildenberg, M.E.5
Allison, J.P.6
Toes, R.E.7
Offringa, R.8
Melief, C.J.9
-
93
-
-
1642305619
-
CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions
-
Suvas S., Azkur A. K., Kim B. S., Kumaraguru U. and Rouse B. T. (2004): CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions. J. Immunol., 172, 4123-4132.
-
(2004)
J. Immunol.
, vol.172
, pp. 4123-4132
-
-
Suvas, S.1
Azkur, A.K.2
Kim, B.S.3
Kumaraguru, U.4
Rouse, B.T.5
-
94
-
-
0141449974
-
CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
-
Suvas S., Kumaraguru U., Pack C. D., Lee S. and Rouse B. T. (2003): CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J. Exp. Med., 198, 889-901.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 889-901
-
-
Suvas, S.1
Kumaraguru, U.2
Pack, C.D.3
Lee, S.4
Rouse, B.T.5
-
95
-
-
0036721772
-
The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
-
Szanya V., Ermann J., Taylor C., Holness C. and Fathman C. G. (2002): The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. J. Immunol., 169, 2461-2465.
-
(2002)
J. Immunol.
, vol.169
, pp. 2461-2465
-
-
Szanya, V.1
Ermann, J.2
Taylor, C.3
Holness, C.4
Fathman, C.G.5
-
96
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T., Kuniyasu Y., Toda M., Sakaguchi N., Itoh M., Iwata M., Shimizu J. and Sakaguchi S. (1998): Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol., 10, 1969-1980.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
97
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi T., Tagami T., Yamazaki S., Uede T., Shimizu J., Sakaguchi N., Mak T. W. and Sakaguchi S. (2000): Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med., 192, 303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
Sakaguchi, S.8
-
98
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory t cells suppress autoimmune diabetes
-
Tang Q., Henriksen K. J., Bi M., Finger E. B., Szot G., Ye J., Masteller E. L., McDevitt H., Bonyhadi M. and Bluestone J. A. (2004): In vitro-expanded antigen-specific regulatory t cells suppress autoimmune diabetes. J. Exp. Med., 199, 1455-1465.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
99
-
-
9444280125
-
L-Selectin (hi) but not the L-Selectin (lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
-
Taylor P. A., Panoskaltsis-Mortari A, Swedin J. M., Lucas P. J., Gress R. E., Levine B. L., June C. H., Serody J. S. and Blazar B. R. (2004): L-Selectin (hi) but not the L-Selectin (lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood, 104, 3804-3812.
-
(2004)
Blood
, vol.104
, pp. 3804-3812
-
-
Taylor, P.A.1
Panoskaltsis-Mortari, A.2
Swedin, J.M.3
Lucas, P.J.4
Gress, R.E.5
Levine, B.L.6
June, C.H.7
Serody, J.S.8
Blazar, B.R.9
-
100
-
-
2442637772
-
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
-
Thornton A. M., Donovan E. E., Piccirillo C. A. and Shevach E. M. (2004): Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J. Immunol., 172, 6519-6523.
-
(2004)
J. Immunol.
, vol.172
, pp. 6519-6523
-
-
Thornton, A.M.1
Donovan, E.E.2
Piccirillo, C.A.3
Shevach, E.M.4
-
101
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton A. M. and Shevach E. M. (1998): CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med., 188, 287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
102
-
-
0033985780
-
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
-
Thornton A. M. and Shevach E. M. (2000): Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J. Immunol., 164, 183-190.
-
(2000)
J. Immunol.
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
103
-
-
0035399985
-
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
-
Thorstenson K. M. and Khoruts A. (2001): Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol., 167, 188-195.
-
(2001)
J. Immunol.
, vol.167
, pp. 188-195
-
-
Thorstenson, K.M.1
Khoruts, A.2
-
104
-
-
0345598872
-
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
-
USA
-
Tone M., Tone Y., Adams E., Yates S. F., Frewin M. R., Cobbold S. P. and Waldmann H. (2003): Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc. Natl. Acad. Sci. USA, 100, 15059-15064.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 15059-15064
-
-
Tone, M.1
Tone, Y.2
Adams, E.3
Yates, S.F.4
Frewin, M.R.5
Cobbold, S.P.6
Waldmann, H.7
-
105
-
-
4444300314
-
CD4+CD25+ regulatory T cells in rheumatoid arthritis: Differences in presence, phenotype and function between peripheral blood and synovial fluid
-
van Amelsfort J. M. R., Jacobs K. M. G., Bijlsma J. W., Lafeber F. P. and Taams L. S. (2004): CD4+CD25+ regulatory T cells in rheumatoid arthritis: differences in presence, phenotype and function between peripheral blood and synovial fluid. Arthritis Rheum., 50, 2775-2785.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2775-2785
-
-
Van Amelsfort, J.M.R.1
Jacobs, K.M.G.2
Bijlsma, J.W.3
Lafeber, F.P.4
Taams, L.S.5
-
106
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V., Baecher-Allan C., Weiner H. L. and Hafler D. A. (2004): Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med., 199, 971-979.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
107
-
-
3142737258
-
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
-
Viguier M., Lemaitre F., Verola O., Cho M. S., Gorochov G., Dubertret L., Bachelez H., Kourilsky P. and Ferradini L. (2004): Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J. Immunol., 173, 1444-1453.
-
(2004)
J. Immunol.
, vol.173
, pp. 1444-1453
-
-
Viguier, M.1
Lemaitre, F.2
Verola, O.3
Cho, M.S.4
Gorochov, G.5
Dubertret, L.6
Bachelez, H.7
Kourilsky, P.8
Ferradini, L.9
-
108
-
-
0043244867
-
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
-
Walker L. S., Chodos A., Eggena M., Dooms H. and Abbas A. K. (2003): Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J. Exp. Med., 198, 249-258.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 249-258
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
109
-
-
0346969978
-
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
-
Walker M. R., Kasprowicz D. J., Gersuk V. H., Benard A., Van Landeghen M., Buckner J. H. and Ziegler S. F. (2003): Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J. Clin. Invest., 112, 1437-1443.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1437-1443
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
Benard, A.4
Van Landeghen, M.5
Buckner, J.H.6
Ziegler, S.F.7
-
110
-
-
2142660657
-
Regulatory cells in transplantation
-
Wood K. J., Ushigome H., Karim M., Bushell A., Hori S. and Sakaguchi S. (2003): Regulatory cells in transplantation. Novartis Found Symp., 252, 177-188.
-
(2003)
Novartis Found Symp.
, vol.252
, pp. 177-188
-
-
Wood, K.J.1
Ushigome, H.2
Karim, M.3
Bushell, A.4
Hori, S.5
Sakaguchi, S.6
-
111
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K. and Steinman R. M. (2003): Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med., 198, 235-247.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
Inaba, K.6
Steinman, R.M.7
-
112
-
-
2442655250
-
Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
-
Yang Y., Huang C.T., Huang X. and Pardoll D. M. (2004): Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat. Immunol., 5, 508-515.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 508-515
-
-
Yang, Y.1
Huang, C.T.2
Huang, X.3
Pardoll, D.M.4
-
113
-
-
1042269477
-
IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells
-
Zhang X., Koldzic D. N., Izikson L., Reddy J., Nazareno R. F., Sakaguchi S., Kuchroo V. K. and Weiner H. L. (2004): IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells. Int. Immunol., 16, 249-256.
-
(2004)
Int. Immunol.
, vol.16
, pp. 249-256
-
-
Zhang, X.1
Koldzic, D.N.2
Izikson, L.3
Reddy, J.4
Nazareno, R.F.5
Sakaguchi, S.6
Kuchroo, V.K.7
Weiner, H.L.8
-
114
-
-
0037108485
-
Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors
-
Zheng S. G., Gray J. D., Ohtsuka K., Yamagiwa S. and Horwitz D. A. (2002): Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors. J. Immunol., 169, 4183-4189.
-
(2002)
J. Immunol.
, vol.169
, pp. 4183-4189
-
-
Zheng, S.G.1
Gray, J.D.2
Ohtsuka, K.3
Yamagiwa, S.4
Horwitz, D.A.5
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