CD4+CD25+ T cells as immunoregulatory T cells in vitro

European Journal of Immunology

Volumn 32, Issue 8, 2002, Pages 2365-2375

  Chai, Jian Guo ^a   Tsang, Julia Y S ^a   Lechler, Robert ^a   Simpson, Elizabeth ^a   Dyson, Julian ^a   Scott, Diane ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Regulation; Suppression; T lymphocyte

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL LINE; CELL SEPARATION; CELL STRAIN; CONTROLLED STUDY; CROSS LINKING; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD4; ANTIGENS, CD95; ANTIGENS, DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; FAS LIGAND PROTEIN; IMMUNOCONJUGATES; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 0036686399     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200208)32:8<2365::AID-IMMU2365>3.0.CO;2-2     Document Type: Article

References (21)

1. Immunological self-tolerance maintained by activated T cells expressing IL-2 receptor a chain. Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
2. + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
3. + T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
4. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
5. + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunological self-tolerance
6. + immunoregulatory T cells that control autoimmune diabetes
7. + immunoregulatory T cells suppress pollyclonal T cell activation in vitro by inhibiting interleukin 2 production
8. + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
9. + immunoregulatory T cells is antigen nonspecific
10. + immunoregulatory cells
11. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
12. + regulatory T cells down-regulate co-stimulatroy molecules on antigen-presenting cells
13. CTLA-4 regulates induction of anergy in vivo
14. Suppressor T cells regulate the nonanergic T cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vb8.1-transgenic mice
15. Anergic T cells inhibit the antigen presenting function of dendritic cells
16. + T cells with regulatroy properties by repetitive stimulation with allogeneic immature human dendritic cells
17. + T cells
18. + T cells or B cells
19. + TCRIo thymocytes in vivo
20. T cell receptor antagonist peptides induce positive selection
21. Dendritic cells permit identification of genes encoding MHC class II-restricted isotopes of transplantation antigens