-
1
-
-
0033985780
-
+ immunoregulatory T cells is antigen nonspecific
-
+ immunoregulatory T cells is antigen nonspecific. J. Immunol. 2000. 164: 183-190.
-
(2000)
J. Immunol.
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
2
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998. 188: 287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
3
-
-
0037099613
-
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
Piccirillo, C. A., Letterio, J. J., Thornton, A. M., McHugh, R. S., Mamura, M., Mizuhara, H. and Shevach, E. M., CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J. Exp. Med. 2002. 196: 237-246.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
4
-
-
0035806244
-
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
-
Dieckmann, D., Plottner, H., Berchtold, S., Berger, T. and Schuler, G., Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J. Exp. Med. 2001. 193: 1303-1310.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1303-1310
-
-
Dieckmann, D.1
Plottner, H.2
Berchtold, S.3
Berger, T.4
Schuler, G.5
-
5
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., Sarukhan, A., Klein, L. and von Boehmer, H., Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 2002. 3: 756-763.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
von Boehmer, H.4
-
6
-
-
0035806323
-
Human CD25(+)CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings, M. K., Sangregorio, R. and Roncarolo, M. G., Human CD25(+)CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 2001. 193: 1295-1302.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
7
-
-
0035806290
-
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
-
Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J. and Enk, A. H., Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 2001. 193: 1285-1294.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1285-1294
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
8
-
-
0037131969
-
+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells
-
+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J. Exp. Med. 2002. 196: 1335-1346.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1335-1346
-
-
Levings, M.K.1
Sangregorio, R.2
Sartirana, C.3
Moschin, A.L.4
Battaglia, M.5
Orban, P.C.6
Roncarolo, M.G.7
-
9
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L. and Powrie, F., An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 1999. 190: 995-1004.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
10
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read, S., Malmstrom, V. and Powrie, F., Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 2000. 192: 295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
11
-
-
0036467522
-
+ regulatory T cells prevent graft rejection: CTLA-4-and IL-10-dependent immunoregulation of alloresponses
-
+ regulatory T cells prevent graft rejection: CTLA-4-and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 2002. 168: 1080-1086.
-
(2002)
J. Immunol.
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
13
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse, P., Penninger, J. M., Timms, E., Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B., Griesser, H. and Mak, T. W., Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995. 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
14
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E. A., Borriello, F., Schweitzer, A. N., Lynch, W. P., Bluestone, J. A. and Sharpe, A. H., Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995. 3: 541-547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
15
-
-
0037103325
-
Re-establishing peripheral tolerance in the absence of CTLA-4: Complementation by wild-type T cells points to an indirect role for CTLA-4
-
Tivol, E. A. and Gorski, J., Re-establishing peripheral tolerance in the absence of CTLA-4: complementation by wild-type T cells points to an indirect role for CTLA-4. J. Immunol. 2002. 169: 1852-1858.
-
(2002)
J. Immunol.
, vol.169
, pp. 1852-1858
-
-
Tivol, E.A.1
Gorski, J.2
-
16
-
-
0344299189
-
Cutting edge: Lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous
-
Bachmann, M. F., Kohler, G., Ecabert, B., Mak, T. W. and Kopf, M., Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J. Immunol. 1999. 163: 1128-1131.
-
(1999)
J. Immunol.
, vol.163
, pp. 1128-1131
-
-
Bachmann, M.F.1
Kohler, G.2
Ecabert, B.3
Mak, T.W.4
Kopf, M.5
-
17
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T., Tagami, T., Yamazaki, S., Uede, T., Shimizu, J., Sakaguchi, N., Mak, T. W. and Sakaguchi, S., Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 2000. 192: 303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
Sakaguchi, S.8
-
18
-
-
0031154577
-
CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
-
Tivol, E. A., Boyd, S. D., McKeon, S., Borriello, F., Nickerson, P., Strom, T. B. and Sharpe, A. H., CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J. Immunol. 1997. 158: 5091-5094.
-
(1997)
J. Immunol.
, vol.158
, pp. 5091-5094
-
-
Tivol, E.A.1
Boyd, S.D.2
McKeon, S.3
Borriello, F.4
Nickerson, P.5
Strom, T.B.6
Sharpe, A.H.7
-
19
-
-
0035871805
-
The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy
-
Yamamoto, A. M., Chernajovsky, Y., Lepault, F., Podhajcer, O., Feldmann, M., Bach, J. F. and Chatenoud, L., The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy. J. Immunol. 2001. 166: 4973-4980.
-
(2001)
J. Immunol.
, vol.166
, pp. 4973-4980
-
-
Yamamoto, A.M.1
Chernajovsky, Y.2
Lepault, F.3
Podhajcer, O.4
Feldmann, M.5
Bach, J.F.6
Chatenoud, L.7
-
20
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. and Sakaguchi, S., Control of regulatory T cell development by the transcription factor Foxp3. Science 2003. 299: 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
24
-
-
0141920662
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunol. 2003. 171: 3348-3352.
-
(2003)
J. Immunol.
, vol.171
, pp. 3348-3352
-
-
Tang, Q.1
Henriksen, K.J.2
Boden, E.K.3
Tooley, A.J.4
Ye, J.5
Subudhi, S.K.6
Zheng, X.X.7
Strom, T.B.8
Bluestone, J.A.9
-
25
-
-
0032538819
-
Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
-
Chen, W., Jin, W. and Wahl, S. M., Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells. J. Exp. Med. 1998. 188: 1849-1857.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1849-1857
-
-
Chen, W.1
Jin, W.2
Wahl, S.M.3
-
26
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura, K., Kitani, A. and Strober, W., Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 2001. 194: 629-644.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
27
-
-
0035956905
-
Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
-
Sullivan, T. J., Letterio, J. J., van Elsas, A., Mamura, M., van Amelsfort, J., Sharpe, S., Metzler, B., Chambers, C. A. and Allison, J. P., Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation. Proc. Natl. Acad. Sci. USA 2001. 98: 2587-2592.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2587-2592
-
-
Sullivan, T.J.1
Letterio, J.J.2
van Elsas, A.3
Mamura, M.4
van Amelsfort, J.5
Sharpe, S.6
Metzler, B.7
Chambers, C.A.8
Allison, J.P.9
-
28
-
-
0033386176
-
TGF-beta: From latent to active
-
Khalil, N., TGF-beta: from latent to active. Microbes Infect. 1999. 1: 1255-1263.
-
(1999)
Microbes Infect.
, vol.1
, pp. 1255-1263
-
-
Khalil, N.1
-
29
-
-
0033603827
-
Cellular response to latent TGF-beta1 is facilitated by insulin-like growth factor-II/mannose-6-phosphate receptors on MS-9 cells
-
Ghahary, A., Tredget, E. E., Mi, L. and Yang, L., Cellular response to latent TGF-beta1 is facilitated by insulin-like growth factor-II/mannose-6-phosphate receptors on MS-9 cells. Exp. Cell Res. 1999. 251: 111-120.
-
(1999)
Exp. Cell Res.
, vol.251
, pp. 111-120
-
-
Ghahary, A.1
Tredget, E.E.2
Mi, L.3
Yang, L.4
-
30
-
-
0344026339
-
M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1
-
Godar, S., Horejsi, V., Weidle, U. H., Binder, B. R., Hansmann, C. and Stockinger, H., M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1. Eur. J. Immunol. 1999. 29: 1004-1013.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 1004-1013
-
-
Godar, S.1
Horejsi, V.2
Weidle, U.H.3
Binder, B.R.4
Hansmann, C.5
Stockinger, H.6
-
31
-
-
0028268212
-
Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta
-
Odekon, L. E., Blasi, F. and Rifkin, D. B., Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta. J. Cell Physiol. 1994. 158: 398-407.
-
(1994)
J. Cell Physiol.
, vol.158
, pp. 398-407
-
-
Odekon, L.E.1
Blasi, F.2
Rifkin, D.B.3
-
32
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas, T. L., Lenschow, D. J., Bakker, C. Y., Linsley, P. S., Freeman, G. J., Green, J. M., Thompson, C. B. and Bluestone, J. A., CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994. 1: 405-413.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
33
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
Walunas, T. L., Bakker, C. Y. and Bluestone, J. A., CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 1996. 183: 2541-2550.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
34
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M. and Byrne, M. C., CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002. 16: 311-323.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
Young, D.A.4
Shevach, E.M.5
Collins, M.6
Byrne, M.C.7
-
35
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y. and Sakaguchi, S., Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol. 2002. 3: 135-142.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
36
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U., Orabona, C., Fallarino, F., Vacca, C., Calcinaro, F., Falorni, A., Candeloro, P., Belladonna, M. L., Bianchi, R., Fioretti, M. C. and Puccetti, P., CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat. Immunol. 2002. 3: 1097-1101.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
Candeloro, P.7
Belladonna, M.L.8
Bianchi, R.9
Fioretti, M.C.10
Puccetti, P.11
-
37
-
-
0036852242
-
When ligand becomes receptor-tolerance via B7 signaling on DCs
-
Finger, E. B. and Bluestone, J. A., When ligand becomes receptor-tolerance via B7 signaling on DCs. Nat. Immunol. 2002. 3: 1056-1057.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1056-1057
-
-
Finger, E.B.1
Bluestone, J.A.2
-
38
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
Bluestone, J. A. and Abbas, A. K., Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 2003. 3: 253-257.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 253-257
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
39
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo, M. G., Bacchetta, R., Bordignon, C., Narula, S. and Levings, M. K., Type 1 T regulatory cells. Immunol. Rev. 2001. 182: 68-79.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 68-79
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
40
-
-
0036886390
-
The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
-
Levings, M. K., Bacchetta, R., Schulz, U. and Roncarolo, M. G., The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int. Arch. Allergy Immunol. 2002. 129: 263-276.
-
(2002)
Int. Arch. Allergy Immunol.
, vol.129
, pp. 263-276
-
-
Levings, M.K.1
Bacchetta, R.2
Schulz, U.3
Roncarolo, M.G.4
-
43
-
-
0037379654
-
TGF-beta: The missing link in CD4(+)CD25(+) regulatory T cell-mediated immunosuppression
-
Chen, W. and Wahl, S. M., TGF-beta: the missing link in CD4(+)CD25(+) regulatory T cell-mediated immunosuppression. Cytokine Growth Factor Rev. 2003. 14: 85-89.
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 85-89
-
-
Chen, W.1
Wahl, S.M.2
-
44
-
-
0037080032
-
The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis
-
Fuss, I. J., Boirivant, M., Lacy, B. and Strober, W., The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis. J. Immunol. 2002. 168: 900-908.
-
(2002)
J. Immunol.
, vol.168
, pp. 900-908
-
-
Fuss, I.J.1
Boirivant, M.2
Lacy, B.3
Strober, W.4
-
45
-
-
0032526354
-
+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production
-
+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production. J. Immunol. 1998. 160: 5719-5728.
-
(1998)
J. Immunol.
, vol.160
, pp. 5719-5728
-
-
Seder, R.A.1
Marth, T.2
Sieve, M.C.3
Strober, W.4
Letterio, J.J.5
Roberts, A.B.6
Kelsall, B.7
-
46
-
-
0037320926
-
CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment
-
Bour-Jordan, H., Grogan, J. L., Tang, Q., Auger, J. A., Locksley, R. M. and Bluestone, J. A., CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment. Nat. Immunol. 2003. 4: 182-188.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 182-188
-
-
Bour-Jordan, H.1
Grogan, J.L.2
Tang, Q.3
Auger, J.A.4
Locksley, R.M.5
Bluestone, J.A.6
|