Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood

Immunology

Volumn 106, Issue 2, 2002, Pages 190-199

  Wing, Kajsa ^a   Ekmark, Ann ^a   Karlsson, Helen ^a   Rudin, Anna ^a   Suri Payer, Elisabeth ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS ANTIGEN; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA; PADGEM PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS; UMBILICAL CORD BLOOD;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; FETAL BLOOD; HUMANS; IMMUNOPHENOTYPING; INFANT, NEWBORN; LYMPHOCYTE ACTIVATION; MIDDLE AGED; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 0036284229     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2002.01412.x     Document Type: Article

References (42)

1. T lymphocyte tolerance: From thymic deletion to peripheral control mechanisms
2. 'Promiscuous' expression of tissue antigens in the thymus: A key to T-cell tolerance and autoimmunity?
3. Regulatory T cells in autoimmunity
4. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
5. + immunoregulatory T cells that control autoimmune diabetes
6. + T cells in the regulation of inflammatory responses in the intestine
7. + T cells that prevent diabetes onset in nonobese diabetic mice
8. - thymocytes
9. + regulatory cells that control intestinal inflammation
10. + immunoregulatory T cells is antigen nonspecific
11. + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
12. + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
13. + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
14. - subpopulations
15. + thymocytes expressing L-selectin mediate 'active tolerance' in the nonobese diabetic mouse
16. Expression of cytokine receptors by human cord blood lymphocytes: Comparison with adult blood lymphocytes
17. + T cells expressing IL-2 receptor alpha-chain (CD25) and having a functionally transitional nature into memory cells
18. + T cells
19. Purification of cord blood lymphocytes
20. + T cells with regulatory properties isolated from peripheral blood
21. + T cells: A highly differentiated and apoptosis-prone population
22. + thymocytes and peripheral T cells have immune suppressive activity in vitro
23. + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
24. + T cells with regulatory properties from human blood
25. high regulatory cells in human peripheral blood
26. The interleukin-2 receptor
27. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
28. Regulation of surface and intracellular expression of CTLA4 on mouse T cells
29. Phenotypic analysis of CTLA-4 and CD28 expression during transient peptide-induced T cell activation in vivo
30. + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
31. Expression of functional B7 and CTLA4 on rheumatoid synovial T cells
32. + thymocytes and identification of thymic emigrants
33. Exclusion of circulating T cells from the thymus does not apply in the neonatal period
34. Re-entry of T cells to the adult thymus is restricted to activated T cells
35. Both activated and nonactivated leukocytes from the periphery continuously enter the thymic medulla of adult rats: Phenotypes, sources and magnitude of traffic
36. + unprimed T cells
37. + regulatory T cells induced by an agonist self-peptide
38. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
39. + T cells
40. + T cells
41. CD38: A multi-lineage cell activation molecule with a split personality
42. + lymphocytes. Role of the human CD38 molecule