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Volumn 104, Issue 10, 2004, Pages 3249-3256

Human immunodeficiency virus-driven expansion of CD4+CD25 + regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN P24; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; INTERLEUKIN 10; MONOCLONAL ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; TUBERCULIN;

EID: 8644280556     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-01-0365     Document Type: Article
Times cited : (350)

References (50)
  • 1
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
    • Rosenberg ES, Billingsley JM, Calliendo AM, et al. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science. 1997;278:1447-1450.
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingsley, J.M.2    Calliendo, A.M.3
  • 2
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • Autran B, Carcelain G, Li TS, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science. 1997;277:112-116.
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Li, T.S.3
  • 3
    • 0033010260 scopus 로고    scopus 로고
    • Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy: INCAS Study Group
    • Pakker NG, Kroon ED, Roos MT, et al. Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy: INCAS Study Group. AIDS. 1999;13:203-212.
    • (1999) AIDS , vol.13 , pp. 203-212
    • Pakker, N.G.1    Kroon, E.D.2    Roos, M.T.3
  • 4
    • 0035423963 scopus 로고    scopus 로고
    • Reconstitution of CD4+ T lymphocytes in HIV-infected individuals following antiretroviral therapy
    • Carcelain G, Debre P, Autran B. Reconstitution of CD4+ T lymphocytes in HIV-infected individuals following antiretroviral therapy. Curr Opin Immunol. 2001;13:483-488.
    • (2001) Curr Opin Immunol , vol.13 , pp. 483-488
    • Carcelain, G.1    Debre, P.2    Autran, B.3
  • 5
    • 0029150110 scopus 로고
    • Immunologic tolerance maintained by activated T cells expressing IL-2 receptor a-chain (CD25): Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic tolerance maintained by activated T cells expressing IL-2 receptor a-chain (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 6
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic-suppressive state
    • Takahashi T, Kuniyasu Y, Toda M, et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic-suppressive state. Int Immunol. 1998;10:1969-1980.
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3
  • 7
    • 0035806323 scopus 로고    scopus 로고
    • Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • Levings MK, Sangregorio R, Roncarolo M-G. Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med. 2001;193:1295-1301.
    • (2001) J Exp Med , vol.193 , pp. 1295-1301
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.-G.3
  • 8
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood. J Exp Med. 2001;193:1303-1310.
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 10
    • 0035421654 scopus 로고    scopus 로고
    • Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
    • Piccirillo CA, Shevach EM. Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol. 2001;167:1137-1140.
    • (2001) J Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 11
    • 0033064551 scopus 로고    scopus 로고
    • Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells
    • Suri-Payer E, Amar AZ, McHugh RS, Natarajan K, Margulies DH, Shevach EM. Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells. Eur J Immunol. 1999;29:669-677.
    • (1999) Eur J Immunol , vol.29 , pp. 669-677
    • Suri-Payer, E.1    Amar, A.Z.2    McHugh, R.S.3    Natarajan, K.4    Margulies, D.H.5    Shevach, E.M.6
  • 12
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
    • Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J Exp Med. 2000;192:295-302.
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 13
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, Tagami T, Yamazaki S, et al. Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2000;192:303-309.
    • (2000) J Exp Med , vol.192 , pp. 303-309
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3
  • 14
    • 0037111521 scopus 로고    scopus 로고
    • CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: Implications for anti-CD154 immunotherapy
    • van Maurik A, Herber M, Wood KJ, Jones ND. CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy. J Immunol. 2002;169:5401-5404.
    • (2002) J Immunol , vol.169 , pp. 5401-5404
    • Van Maurik, A.1    Herber, M.2    Wood, K.J.3    Jones, N.D.4
  • 15
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol. 2003;3:199-211.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-211
    • Wood, K.J.1    Sakaguchi, S.2
  • 16
    • 0035062581 scopus 로고    scopus 로고
    • Human anergic/suppressive CD4+CD25+ T cells: A highly differentiated and apoptosis-prone population
    • Taams LS, Smith J, Rustin MH, Salmon M, Poulter LW, Akbar AN. Human anergic/suppressive CD4+CD25+ T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol. 2001;31:1122-1131.
    • (2001) Eur J Immunol , vol.31 , pp. 1122-1131
    • Taams, L.S.1    Smith, J.2    Rustin, M.H.3    Salmon, M.4    Poulter, L.W.5    Akbar, A.N.6
  • 18
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming-growth-factor-beta secreting Th3 regulatory cells
    • Weiner HL. Induction and mechanism of action of transforming-growth- factor-beta secreting Th3 regulatory cells. Immunol Rev. 2001;182:207-214.
    • (2001) Immunol Rev , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 19
    • 0037131969 scopus 로고    scopus 로고
    • Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells
    • Levings MK, Sangregorio R, Sartriana C, et al. Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med. 2002;196:1335-1346.
    • (2002) J Exp Med , vol.196 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartriana, C.3
  • 20
    • 0033372246 scopus 로고    scopus 로고
    • Restoration of normal interleukin-2 production by CD4+ T cells of human immunodeficiency virus-infected patients after 9 months of highly active antiretroviral therapy
    • Weiss L, Ancula P, Girard PM, et al. Restoration of normal interleukin-2 production by CD4+ T cells of human immunodeficiency virus-infected patients after 9 months of highly active antiretroviral therapy. J Infect Dis. 1999;180:1057-1063.
    • (1999) J Infect Dis , vol.180 , pp. 1057-1063
    • Weiss, L.1    Ancula, P.2    Girard, P.M.3
  • 21
    • 0037436193 scopus 로고    scopus 로고
    • Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-infection: A randomized control trial
    • Levy Y, Durier C, Krzysiek R, et al. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-infection: a randomized control trial. AIDS. 2003;17:343-351.
    • (2003) AIDS , vol.17 , pp. 343-351
    • Levy, Y.1    Durier, C.2    Krzysiek, R.3
  • 22
    • 0024272153 scopus 로고
    • Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men: HIV affects the immune system before CD4+ T helper cell depletion occurs
    • Miedema F, Petit AJ, Terpstra FG, et al. Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men: HIV affects the immune system before CD4+ T helper cell depletion occurs. J Clin Invest. 1988;82:1908-1914.
    • (1988) J Clin Invest , vol.82 , pp. 1908-1914
    • Miedema, F.1    Petit, A.J.2    Terpstra, F.G.3
  • 23
    • 0024786954 scopus 로고
    • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: Independence of CD4+ cell numbers and clinical staging
    • Clerici M, Stocks NI, Zajac RA, et al. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: independence of CD4+ cell numbers and clinical staging. J Clin Invest. 1989;84:1892-1899.
    • (1989) J Clin Invest , vol.84 , pp. 1892-1899
    • Clerici, M.1    Stocks, N.I.2    Zajac, R.A.3
  • 24
    • 0037105607 scopus 로고    scopus 로고
    • Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: Characterization of a novel subset of CD4+/CD25+ T cells
    • Sereti I, Martinez-Wilson H, Metcalf J, et al. Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4+/CD25+ T cells. Blood. 2002;100:2159-2167.
    • (2002) Blood , vol.100 , pp. 2159-2167
    • Sereti, I.1    Martinez-Wilson, H.2    Metcalf, J.3
  • 25
    • 0029974048 scopus 로고    scopus 로고
    • Heterogeneity of the human CD4+ T-cell population: Two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms
    • Hamann D, Baars PA, Hooibrink B, van Lier RW. Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms. Blood. 1996;88:3513-3521.
    • (1996) Blood , vol.88 , pp. 3513-3521
    • Hamann, D.1    Baars, P.A.2    Hooibrink, B.3    Van Lier, R.W.4
  • 26
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med. 1999;190:995-1004.
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 27
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med. 2001;193:1285-1294.
    • (2001) J Exp Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 28
    • 0032805881 scopus 로고    scopus 로고
    • Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection
    • Kalams SA, Buchbinder SP, Rosenberg ES, et al. Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection. J Virol. 1999;73:6715-6720.
    • (1999) J Virol , vol.73 , pp. 6715-6720
    • Kalams, S.A.1    Buchbinder, S.P.2    Rosenberg, E.S.3
  • 29
    • 0036086232 scopus 로고    scopus 로고
    • Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells
    • Taams LS, Vukmanovic-Stejic M, Smith J, et al. Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells. Eur J Immunol. 2002;32:1621-1630.
    • (2002) Eur J Immunol , vol.32 , pp. 1621-1630
    • Taams, L.S.1    Vukmanovic-Stejic, M.2    Smith, J.3
  • 30
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HS, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol. 2002;169:2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.S.3
  • 31
    • 0037099719 scopus 로고    scopus 로고
    • Infectious tolerance: Human CD25+ regulatory T cells convey suppressor activity to conventional CD4+ T helper cells
    • Jonuleit H, Schlmitt E, Kakirman H, Stassen M, Knop J, Enk AH. Infectious tolerance: human CD25+ regulatory T cells convey suppressor activity to conventional CD4+ T helper cells. J Exp Med. 2002;196:255-260.
    • (2002) J Exp Med , vol.196 , pp. 255-260
    • Jonuleit, H.1    Schlmitt, E.2    Kakirman, H.3    Stassen, M.4    Knop, J.5    Enk, A.H.6
  • 32
    • 0037040351 scopus 로고    scopus 로고
    • CTLA-4 upregulation during HIV infection: Association with anergy and possible target for therapeutic intervention
    • Leng Q, Bentwich Z, Magen E, Kalinkovich A, Borkow G. CTLA-4 upregulation during HIV infection: association with anergy and possible target for therapeutic intervention. AIDS. 2002;16:519-529.
    • (2002) AIDS , vol.16 , pp. 519-529
    • Leng, Q.1    Bentwich, Z.2    Magen, E.3    Kalinkovich, A.4    Borkow, G.5
  • 33
    • 0037026003 scopus 로고    scopus 로고
    • Phenotype, localization and mechanism of suppression of CD4+CD25+ human thymocytes
    • Annunziato F, Cosmi L, Liotta F, et al. Phenotype, localization and mechanism of suppression of CD4+CD25+ human thymocytes. J Exp Med. 2002;196:379-387.
    • (2002) J Exp Med , vol.196 , pp. 379-387
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3
  • 34
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory Tcells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory Tcells. Nat Immunol. 2003;4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 35
    • 0346969978 scopus 로고    scopus 로고
    • Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
    • Walker MR, Kasprowicz DJ, Gersuk VH, et al. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J Clin Invest. 2003;112:1437-1443.
    • (2003) J Clin Invest , vol.112 , pp. 1437-1443
    • Walker, M.R.1    Kasprowicz, D.J.2    Gersuk, V.H.3
  • 36
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev. 2001; 182:18-32.
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 37
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol. 2003;3:253-257.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 38
    • 0037007670 scopus 로고    scopus 로고
    • HIV preferentially infects HIV-speci!ic CD4+ T cells
    • Douek DC, Brenchley JM, Betts MR, et al. HIV preferentially infects HIV-speci!ic CD4+ T cells. Nature. 2002;417:95-98.
    • (2002) Nature , vol.417 , pp. 95-98
    • Douek, D.C.1    Brenchley, J.M.2    Betts, M.R.3
  • 39
    • 0034254205 scopus 로고    scopus 로고
    • CD40 ligand trimer and IL-12 enhance peripheral blood mononuclear cells and CD4+ T cell proliferation and production of IFN-gamma in response to p24 antigen in HIV-infected individuals: Potential contribution of anergy to HIV-specific unresponsiveness
    • Dybul M, Mercier G, Belson M, et al. CD40 ligand trimer and IL-12 enhance peripheral blood mononuclear cells and CD4+ T cell proliferation and production of IFN-gamma in response to p24 antigen in HIV-infected individuals: potential contribution of anergy to HIV-specific unresponsiveness. J Immunol. 2000;165:1685-1691.
    • (2000) J Immunol , vol.165 , pp. 1685-1691
    • Dybul, M.1    Mercier, G.2    Belson, M.3
  • 40
    • 0034743924 scopus 로고    scopus 로고
    • Human immunodeficiency virus palhogenesis and prospects for immune control in patients with established infection
    • Cohen DE, Walker BD. Human immunodeficiency virus palhogenesis and prospects for immune control in patients with established infection. Clin Infect Dis. 2001;32:1756-1768.
    • (2001) Clin Infect Dis , vol.32 , pp. 1756-1768
    • Cohen, D.E.1    Walker, B.D.2
  • 42
    • 0035876913 scopus 로고    scopus 로고
    • A role for TGF-b in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood
    • Yamagiva S, Gray JD, Hashimoto S, Horwitz DA. A role for TGF-b in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J Immunol. 2001;166:7282-7289.
    • (2001) J Immunol , vol.166 , pp. 7282-7289
    • Yamagiva, S.1    Gray, J.D.2    Hashimoto, S.3    Horwitz, D.A.4
  • 43
    • 0037097593 scopus 로고    scopus 로고
    • Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40-CD40L costimulatory pathway results in a generation of a potent immune regulatory cell
    • Taylor PA, Friedman TM, Korngold R, Noelle RJ, Blazar BR. Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40-CD40L costimulatory pathway results in a generation of a potent immune regulatory cell. Blood. 2002;99:4601-4609.
    • (2002) Blood , vol.99 , pp. 4601-4609
    • Taylor, P.A.1    Friedman, T.M.2    Korngold, R.3    Noelle, R.J.4    Blazar, B.R.5
  • 44
    • 0029010739 scopus 로고
    • HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71)
    • Chirmule N, McCloskey TW, Hu R, Kalyanaraman VS, Pahwa S. HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71). J Immunol. 1995;155:2917-2924.
    • (1995) J Immunol , vol.155 , pp. 2917-2924
    • Chirmule, N.1    McCloskey, T.W.2    Hu, R.3    Kalyanaraman, V.S.4    Pahwa, S.5
  • 45
    • 0035923542 scopus 로고    scopus 로고
    • High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferation
    • McNeil AC, Shupert WL, Iyasere CA, et al. High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferation. Proc Natl Acad Sci U S A. 2001;98:13878-13883.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13878-13883
    • McNeil, A.C.1    Shupert, W.L.2    Iyasere, C.A.3
  • 46
    • 0030726383 scopus 로고    scopus 로고
    • Host factors in the pathogenesis of HIV disease
    • Cohen OJ, Kinter A, Fauci AS. Host factors in the pathogenesis of HIV disease. Immunol Rev. 1997;159:31-48.
    • (1997) Immunol Rev , vol.159 , pp. 31-48
    • Cohen, O.J.1    Kinter, A.2    Fauci, A.S.3
  • 48
    • 0036499256 scopus 로고    scopus 로고
    • HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells
    • Garba ML, Pilcher CD, Bingham AL, Eron J, Frelinger JA. HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells. J Immunol. 2002;168:2247-2254.
    • (2002) J Immunol , vol.168 , pp. 2247-2254
    • Garba, M.L.1    Pilcher, C.D.2    Bingham, A.L.3    Eron, J.4    Frelinger, J.A.5
  • 49
    • 0037099733 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-idependent type-1-like regulatory T cells
    • Dieckmann D, Bruett CH, Ploettner H, Lutz MB, Schuler G. Human CD4+CD25+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-idependent type-1-like regulatory T cells. J Exp Med. 2002;196:247-253.
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 50
    • 0036467410 scopus 로고    scopus 로고
    • Human anergic CD4+ T cells can act as suppressor cells by affecting autologous dendritic cell conditioning and survival
    • Frasca L, Scotta C, Lombardi G, Piccolella E. Human anergic CD4+ T cells can act as suppressor cells by affecting autologous dendritic cell conditioning and survival. J Immunol. 2002;168:1060-1068.
    • (2002) J Immunol , vol.168 , pp. 1060-1068
    • Frasca, L.1    Scotta, C.2    Lombardi, G.3    Piccolella, E.4


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