Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

Journal of Experimental Medicine

Volumn 201, Issue 5, 2005, Pages 723-735

  Setoguchi, Ruka ^a   Hori, Shohei ^b   Takahashi, Takeshi ^a   Sakaguchi, Shimon ^a,b,c  

^a KYOTO UNIVERSITY   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; GASTRITIS; GENE; GENETIC TRANSCRIPTION; HOMEOSTASIS AND REGULATION; HUMAN; LYMPHOCYTOPENIA; MOUSE; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATOR GENE; SIALOADENITIS; T LYMPHOCYTE; THYMECTOMY; THYMUS; THYROIDITIS;

ANIMALS; ANTIBODIES, MONOCLONAL; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DIABETES MELLITUS; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GASTRITIS; HOMEOSTASIS; INTERLEUKIN-2; LYMPHOPENIA; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; RECEPTORS, INTERLEUKIN-2; TRANSCRIPTION, GENETIC;

EID: 15444374646     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041982     Document Type: Article

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