-
1
-
-
0031959942
-
Autoimmune diabetes: The role of T cells, MHC molecules and autoantigens
-
I. Durinovic-Bello, Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens, Autoimmunity 27 (1998) 159-177.
-
(1998)
Autoimmunity
, vol.27
, pp. 159-177
-
-
Durinovic-Bello, I.1
-
2
-
-
0033141481
-
Mechanisms of central and peripheral T-cell tolerance: Lessons from experimental models of multiple sclerosis
-
S. Anderton, C. Burkhart, B. Metzler, D. Wraith, Mechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis, Immunol. Rev. 169 (1999) 123-137.
-
(1999)
Immunol. Rev.
, vol.169
, pp. 123-137
-
-
Anderton, S.1
Burkhart, C.2
Metzler, B.3
Wraith, D.4
-
3
-
-
0035525528
-
From T to B and back again: Positive feedback in systemic autoimmune disease
-
M.J. Shlomchik, J.E. Craft, M.J. Mamula, From T to B and back again: positive feedback in systemic autoimmune disease, Nat. Rev. Immunol. 1 (2001) 147-153.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 147-153
-
-
Shlomchik, M.J.1
Craft, J.E.2
Mamula, M.J.3
-
4
-
-
0036284984
-
The role of Th1/Th2 polarization in mucosal immunity
-
M.F. Neurath, S. Finotto, L.H. Glimcher, The role of Th1/Th2 polarization in mucosal immunity, Nat. Med. 8 (2002) 567-573.
-
(2002)
Nat. Med.
, vol.8
, pp. 567-573
-
-
Neurath, M.F.1
Finotto, S.2
Glimcher, L.H.3
-
5
-
-
0034667792
-
Orchestrated response: A symphony of transcription factors for gene control
-
B. Lemon, R. Tjian, Orchestrated response: a symphony of transcription factors for gene control, Genes Dev. 14 (2000) 2551-2569.
-
(2000)
Genes Dev.
, vol.14
, pp. 2551-2569
-
-
Lemon, B.1
Tjian, R.2
-
6
-
-
0035499602
-
Gene-selective developmental roles of general transcription factors
-
G.J. Veenstra, A.P. Wolffe, Gene-selective developmental roles of general transcription factors, Trends Biochem. Sci. 26 (2001) 665-671.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 665-671
-
-
Veenstra, G.J.1
Wolffe, A.P.2
-
7
-
-
0031942986
-
Transcriptional regulation during B cell development
-
A. Henderson, K. Calame, Transcriptional regulation during B cell development, Annu. Rev. Immunol. 16 (1998) 163-200.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 163-200
-
-
Henderson, A.1
Calame, K.2
-
8
-
-
0035194463
-
Plasma cells: Finding new light at the end of B cell development
-
K.L. Calame, Plasma cells: finding new light at the end of B cell development, Nat. Immunol. 2 (2001) 1103-1108.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1103-1108
-
-
Calame, K.L.1
-
9
-
-
0036233983
-
Transcription: Tantalizing times for T cells
-
I.C. Ho, L.H. Glimcher, Transcription: tantalizing times for T cells, Cell 109 (2002) S109-S120 (Suppl.).
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ho, I.C.1
Glimcher, L.H.2
-
10
-
-
0036885067
-
The lineage decisions of helper T cells
-
K.M. Murphy, S.L. Reiner, The lineage decisions of helper T cells, Nat. Rev. Immunol. 2 (2002) 933-944.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
11
-
-
0034767917
-
The innate immune system in rheumatoid arthritis
-
W.P. Arend, The innate immune system in rheumatoid arthritis, Arthritis Rheum. 44 (2001) 2224-2234.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 2224-2234
-
-
Arend, W.P.1
-
12
-
-
0035932519
-
Cytokine pathways and joint inflammation in rheumatoid arthritis
-
E.H. Choy, G.S. Panayi, Cytokine pathways and joint inflammation in rheumatoid arthritis, N. Engl. J. Med. 344 (2001) 907-916.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 907-916
-
-
Choy, E.H.1
Panayi, G.S.2
-
13
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
G.S. Firestein, Evolving concepts of rheumatoid arthritis, Nature 423 (2003) 356-361.
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
14
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
Y.Y. Kong, U. Feige, I. Sarosi, B. Bolon, A. Tafuri, S. Morony, C. Capparelli, J. Li, R. Elliott, S. McCabe, T. Wong, G. Campagnuolo, E. Moran, E.R. Bogoch, G. Van, L.T. Nguyen, P.S. Ohashi, D.L. Lacey, E. Fish, W.J. Boyle, J.M. Penninger, Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand, Nature 402 (1999) 304-309.
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
Bolon, B.4
Tafuri, A.5
Morony, S.6
Capparelli, C.7
Li, J.8
Elliott, R.9
McCabe, S.10
Wong, T.11
Campagnuolo, G.12
Moran, E.13
Bogoch, E.R.14
Van, G.15
Nguyen, L.T.16
Ohashi, P.S.17
Lacey, D.L.18
Fish, E.19
Boyle, W.J.20
Penninger, J.M.21
more..
-
15
-
-
0035153246
-
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
-
A.R. Pettit, H. Ji, D. von Stechow, R. Muller, S.R. Goldring, Y. Choi, C. Benoist, E.M. Gravallese, TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis, Am. J. Pathol. 159 (2001) 1689-1699.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 1689-1699
-
-
Pettit, A.R.1
Ji, H.2
Von Stechow, D.3
Muller, R.4
Goldring, S.R.5
Choi, Y.6
Benoist, C.7
Gravallese, E.M.8
-
16
-
-
0035983295
-
NF-kappaB family of transcription factors: Central regulators of innate and adaptive immune functions
-
J. Caamano, C.A. Hunter, NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions, Clin. Microbiol. Rev. 15 (2002) 414-429.
-
(2002)
Clin. Microbiol. Rev.
, vol.15
, pp. 414-429
-
-
Caamano, J.1
Hunter, C.A.2
-
17
-
-
0036781052
-
NF-κB regulation in the immune system
-
Q. Li, I.M. Verma, NF-κB regulation in the immune system, Nat. Rev. Immunol. 2 (2002) 725-734.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
18
-
-
0029563524
-
Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65
-
M.L. Handel, L.B. McMorrow, E.M. Gravallese, Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65, Arthritis Rheum. 38 (1995) 1762-1770.
-
(1995)
Arthritis Rheum.
, vol.38
, pp. 1762-1770
-
-
Handel, M.L.1
McMorrow, L.B.2
Gravallese, E.M.3
-
19
-
-
15844384253
-
Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue
-
R. Marok, P.G. Winyard, A. Coumbe, M.L. Kus, K. Gaffney, S. Blades, P.I. Mapp, C.J. Morris, D.R. Blake, C. Kaltschmidt, P.A. Baeuerle, Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue, Arthritis Rheum. 39 (1996) 583-591.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 583-591
-
-
Marok, R.1
Winyard, P.G.2
Coumbe, A.3
Kus, M.L.4
Gaffney, K.5
Blades, S.6
Mapp, P.I.7
Morris, C.J.8
Blake, D.R.9
Kaltschmidt, C.10
Baeuerle, P.A.11
-
20
-
-
0032428729
-
AP-1 and NF-κB regulation in rheumatoid arthritis and murine collagen-induced arthritis
-
Z. Han, D.L. Boyle, A.M. Manning, G.S. Firestein, AP-1 and NF-κB regulation in rheumatoid arthritis and murine collagen-induced arthritis, Autoimmunity 28 (1998) 197-208.
-
(1998)
Autoimmunity
, vol.28
, pp. 197-208
-
-
Han, Z.1
Boyle, D.L.2
Manning, A.M.3
Firestein, G.S.4
-
21
-
-
0031744967
-
Analysis of the NF-κB p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA
-
M. Sioud, O. Mellbye, O. Forre, Analysis of the NF-κB p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA, Clin. Exp. Rheumatol. 16 (1998) 125-134.
-
(1998)
Clin. Exp. Rheumatol.
, vol.16
, pp. 125-134
-
-
Sioud, M.1
Mellbye, O.2
Forre, O.3
-
22
-
-
0033178749
-
Essential role of T cell NF-κB activation in collagen-induced arthritis
-
R. Seetharaman, A.L. Mora, G. Nabozny, M. Boothby, J. Chen, Essential role of T cell NF-κB activation in collagen-induced arthritis, J. Immunol. 163 (1999) 1577-1583.
-
(1999)
J. Immunol.
, vol.163
, pp. 1577-1583
-
-
Seetharaman, R.1
Mora, A.L.2
Nabozny, G.3
Boothby, M.4
Chen, J.5
-
23
-
-
0034086893
-
Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis
-
C.L. Danning, G.G. Illei, C. Hitchon, M.R. Greer, D.T. Boumpas, I.B. McInnes, Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis, Arthritis Rheum. 43 (2000) 1244-1256.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 1244-1256
-
-
Danning, C.L.1
Illei, G.G.2
Hitchon, C.3
Greer, M.R.4
Boumpas, D.T.5
McInnes, I.B.6
-
24
-
-
0033866750
-
Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates
-
A.R. Pettit, K.P. MacDonald, B. O'Sullivan, R. Thomas, Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates, Arthritis Rheum. 43 (2000) 791-800.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 791-800
-
-
Pettit, A.R.1
MacDonald, K.P.2
O'Sullivan, B.3
Thomas, R.4
-
25
-
-
0033917674
-
Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis
-
I.K. Campbell, S. Gerondakis, K. O'Donnell, I.P. Wicks, Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis, J. Clin. Invest. 105 (2000) 1799-1806.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1799-1806
-
-
Campbell, I.K.1
Gerondakis, S.2
O'Donnell, K.3
Wicks, I.P.4
-
26
-
-
0035865090
-
NF-κB regulation by IκB kinase-2 in rheumatoid arthritis synoviocytes
-
K. Aupperle, B. Bennett, Z. Han, D. Boyle, A. Manning, G. Firestein, NF-κB regulation by IκB kinase-2 in rheumatoid arthritis synoviocytes, J. Immunol. 166 (2001) 2705-2711.
-
(2001)
J. Immunol.
, vol.166
, pp. 2705-2711
-
-
Aupperle, K.1
Bennett, B.2
Han, Z.3
Boyle, D.4
Manning, A.5
Firestein, G.6
-
27
-
-
0034892866
-
Inhibitor of nuclear factor κb kinase β is a key regulator of synovial inflammation
-
P.P. Tak, D.M. Gerlag, K.R. Aupperle, D.A. van de Geest, M. Overbeek, B.L. Bennett, D.L. Boyle, A.M. Manning, G.S. Firestein, Inhibitor of nuclear factor κB kinase β is a key regulator of synovial inflammation, Arthritis Rheum. 44 (2001) 1897-1907.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 1897-1907
-
-
Tak, P.P.1
Gerlag, D.M.2
Aupperle, K.R.3
Van De Geest, D.A.4
Overbeek, M.5
Bennett, B.L.6
Boyle, D.L.7
Manning, A.M.8
Firestein, G.S.9
-
28
-
-
0032505870
-
NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
-
A.V. Miagkov, D.V. Kovalenko, C.E. Brown, J.R. Didsbury, J.P. Cogswell, S.A. Stimpson, A.S. Baldwin, S.S. Makarov, NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint, Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 13859-13864.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 13859-13864
-
-
Miagkov, A.V.1
Kovalenko, D.V.2
Brown, C.E.3
Didsbury, J.R.4
Cogswell, J.P.5
Stimpson, S.A.6
Baldwin, A.S.7
Makarov, S.S.8
-
29
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
-
N. Auphan, J.A. DiDonato, C. Rosette, A. Helmberg, M. Karin, Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis, Science 270 (1995) 286-290.
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
30
-
-
0028879819
-
Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
-
R.I. Scheinman, P.C. Cogswell, A.K. Lofquist, A.S. Baldwin Jr., Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids, Science 270 (1995) 283-286.
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin Jr., A.S.4
-
31
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(κ)B kinase-β
-
M.J. Yin, Y. Yamamoto, R.B. Gaynor, The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(κ)B kinase-β, Nature 396 (1998) 77-80.
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
32
-
-
0032032469
-
Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B
-
C. Wahl, S. Liptay, G. Adler, R.M. Schmid, Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B, J. Clin. Invest. 101 (1998) 1163-1174.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1163-1174
-
-
Wahl, C.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
33
-
-
0033557695
-
Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression
-
S.K. Manna, B.B. Aggarwal, Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression, J. Immunol. 162 (1999) 2095-2102.
-
(1999)
J. Immunol.
, vol.162
, pp. 2095-2102
-
-
Manna, S.K.1
Aggarwal, B.B.2
-
34
-
-
0031919849
-
Jaks and STATs: Biological implications
-
W.J. Leonard, J.J. O'Shea, Jaks and STATs: biological implications, Annu. Rev. Immunol. 16 (1998) 293-322.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
35
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
J.J. O'Shea, M. Gadina, R.D. Schreiber, Cytokine signaling in 2002: new surprises in the Jak/Stat pathway, Cell 109 (2002) S121-S131 (Suppl.).
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
36
-
-
18144438839
-
Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
-
D.M. Frucht, M. Aringer, J. Galon, C. Danning, M. Brown, S. Fan, M. Centola, C.Y. Wu, N. Yamada, H. El Gabalawy, J.J. O'Shea, Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation, J. Immunol. 164 (2000) 4659-4664.
-
(2000)
J. Immunol.
, vol.164
, pp. 4659-4664
-
-
Frucht, D.M.1
Aringer, M.2
Galon, J.3
Danning, C.4
Brown, M.5
Fan, S.6
Centola, M.7
Wu, C.Y.8
Yamada, N.9
El Gabalawy, H.10
O'Shea, J.J.11
-
37
-
-
0028925533
-
Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma
-
T.K. Sengupta, A. Chen, Z. Zhong, J.E. Darnell Jr., L.B. Ivashkiv, Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma, J. Exp. Med. 181 (1995) 1015-1025.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1015-1025
-
-
Sengupta, T.K.1
Chen, A.2
Zhong, Z.3
Darnell Jr., J.E.4
Ivashkiv, L.B.5
-
38
-
-
0028799973
-
Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids
-
F. Wang, T.K. Sengupta, Z. Zhong, L.B. Ivashkiv, Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids, J. Exp. Med. 182 (1995) 1825-1831.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1825-1831
-
-
Wang, F.1
Sengupta, T.K.2
Zhong, Z.3
Ivashkiv, L.B.4
-
39
-
-
0034867446
-
Preferential and persistent activation of the STAT1 pathway in rheumatoid synovial fluid cells
-
A. Yokota, M. Narazaki, Y. Shima, N. Murata, T. Tanaka, M. Suemura, K. Yoshizaki, H. Fujiwara, I. Tsuyuguchi, T. Kishimoto, Preferential and persistent activation of the STAT1 pathway in rheumatoid synovial fluid cells, J. Rheumatol. 28 (2001) 1952-1959.
-
(2001)
J. Rheumatol.
, vol.28
, pp. 1952-1959
-
-
Yokota, A.1
Narazaki, M.2
Shima, Y.3
Murata, N.4
Tanaka, T.5
Suemura, M.6
Yoshizaki, K.7
Fujiwara, H.8
Tsuyuguchi, I.9
Kishimoto, T.10
-
40
-
-
0036734498
-
Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation
-
X. Hu, C. Herrero, W.P. Li, T.T. Antoniv, E. Falck-Pedersen, A.E. Koch, J.M. Woods, G.K. Haines, L.B. Ivashkiv, Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation, Nat. Immunol. 3 (2002) 859-866.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 859-866
-
-
Hu, X.1
Herrero, C.2
Li, W.P.3
Antoniv, T.T.4
Falck-Pedersen, E.5
Koch, A.E.6
Woods, J.M.7
Haines, G.K.8
Ivashkiv, L.B.9
-
41
-
-
0038047126
-
From transcriptome to proteome: Differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies
-
P. Lorenz, P. Ruschpler, D. Koczan, P. Stiehl, H.J. Thiesen, From transcriptome to proteome: differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies, Proteomics 3 (2003) 991-1002.
-
(2003)
Proteomics
, vol.3
, pp. 991-1002
-
-
Lorenz, P.1
Ruschpler, P.2
Koczan, D.3
Stiehl, P.4
Thiesen, H.J.5
-
42
-
-
0042655250
-
Rheumatoid arthritis is a heterogeneous disease: Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues
-
T.C. van der Pouw Kraan, F.A. van Gaalen, P.V. Kasperkovitz, N.L. Verbeet, T.J. Smeets, M.C. Kraan, M. Fero, P.P. Tak, T.W. Huizinga, E. Pieterman, F.C. Breedveld, A.A. Alizadeh, C.L. Verweij, Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues, Arthritis Rheum. 48 (2003) 2132-2145.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 2132-2145
-
-
Van Der Pouw Kraan, T.C.1
Van Gaalen, F.A.2
Kasperkovitz, P.V.3
Verbeet, N.L.4
Smeets, T.J.5
Kraan, M.C.6
Fero, M.7
Tak, P.P.8
Huizinga, T.W.9
Pieterman, E.10
Breedveld, F.C.11
Alizadeh, A.A.12
Verweij, C.L.13
-
43
-
-
0037105475
-
IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms
-
A. Finnegan, M.J. Grusby, C.D. Kaplan, S.K. O'Neill, H. Eibel, T. Koreny, M. Czipri, K. Mikecz, J. Zhang, IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms, J. Immunol. 169 (2002) 3345-3352.
-
(2002)
J. Immunol.
, vol.169
, pp. 3345-3352
-
-
Finnegan, A.1
Grusby, M.J.2
Kaplan, C.D.3
O'Neill, S.K.4
Eibel, H.5
Koreny, T.6
Czipri, M.7
Mikecz, K.8
Zhang, J.9
-
44
-
-
0035340751
-
A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis
-
R. Ortmann, R. Smeltz, G. Yap, A. Sher, E.M. Shevach, A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis, J. Immunol. 166 (2001) 5712-5719.
-
(2001)
J. Immunol.
, vol.166
, pp. 5712-5719
-
-
Ortmann, R.1
Smeltz, R.2
Yap, G.3
Sher, A.4
Shevach, E.M.5
-
45
-
-
0036884944
-
Rheumatoid arthritis synoviocyte survival is dependent on Stat3
-
A. Krause, N. Scaletta, J.D. Ji, L.B. Ivashkiv, Rheumatoid arthritis synoviocyte survival is dependent on Stat3, J. Immunol. 169 (2002) 6610-6616.
-
(2002)
J. Immunol.
, vol.169
, pp. 6610-6616
-
-
Krause, A.1
Scaletta, N.2
Ji, J.D.3
Ivashkiv, L.B.4
-
46
-
-
0035910753
-
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation
-
A. Suzuki, T. Hanada, K. Mitsuyama, T. Yoshida, S. Kamizono, T. Hoshino, M. Kubo, A. Yamashita, M. Okabe, K. Takeda, S. Matsumoto, S. Matsumoto, A. Toyonaga, M. Sata, A. Yoshimura, CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation, J. Exp. Med. 193 (2001) 471-481.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 471-481
-
-
Suzuki, A.1
Hanada, T.2
Mitsuyama, K.3
Yoshida, T.4
Kamizono, S.5
Hoshino, T.6
Kubo, M.7
Yamashita, A.8
Okabe, M.9
Takeda, K.10
Akira, S.11
Matsumoto, S.12
Toyonaga, A.13
Sata, M.14
Yoshimura, A.15
-
47
-
-
0035667907
-
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis
-
T. Shouda, T. Yoshida, T. Hanada, T.Wakioka, M. Oishi, K. Miyoshi, S. Komiya, K. Kosai, Y. Hanakawa, K. Hashimoto, K. Nagata, A. Yoshimura, Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis, J. Clin. Invest. 108 (2001) 1781-1788.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1781-1788
-
-
Shouda, T.1
Yoshida, T.2
Hanada, T.3
Wakioka, T.4
Oishi, M.5
Miyoshi, K.6
Komiya, S.7
Kosai, K.8
Hanakawa, Y.9
Hashimoto, K.10
Nagata, K.11
Yoshimura, A.12
-
48
-
-
0035284754
-
Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway
-
W.Q. Li, F. Dehnade, M. Zafarullah, Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway, J. Immunol. 166 (2001) 3491-3498.
-
(2001)
J. Immunol.
, vol.166
, pp. 3491-3498
-
-
Li, W.Q.1
Dehnade, F.2
Zafarullah, M.3
-
49
-
-
0037466491
-
p21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients
-
M. Hikasa, E. Yamamoto, H. Kawasaki, K. Komai, K. Shiozawa, A. Hashiramoto, Y. Miura, S. Shiozawa, p21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients, Biochem. Biophys. Res. Commun. 304 (2003) 143-147.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 143-147
-
-
Hikasa, M.1
Yamamoto, E.2
Kawasaki, H.3
Komai, K.4
Shiozawa, K.5
Hashiramoto, A.6
Miura, Y.7
Shiozawa, S.8
-
50
-
-
0035971436
-
Partners in transcription: NFAT and AP-1
-
F. Macian, C. Lopez-Rodriguez, A. Rao, Partners in transcription: NFAT and AP-1, Oncogene 20 (2001) 2476-2489.
-
(2001)
Oncogene
, vol.20
, pp. 2476-2489
-
-
Macian, F.1
Lopez-Rodriguez, C.2
Rao, A.3
-
51
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
E. Shaulian, M. Karin, AP-1 as a regulator of cell life and death, Nat. Cell Biol. 4 (2002) E131-E136.
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Shaulian, E.1
Karin, M.2
-
52
-
-
0026624810
-
Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts
-
A. Trabandt, W.K. Aicher, R.E. Gay, V.P. Sukhatme, H.G. Fassbender, S. Gay, Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts, Rheumatol. Int. 12 (1992) 53-59.
-
(1992)
Rheumatol. Int.
, vol.12
, pp. 53-59
-
-
Trabandt, A.1
Aicher, W.K.2
Gay, R.E.3
Sukhatme, V.P.4
Fassbender, H.G.5
Gay, S.6
-
53
-
-
0030009939
-
Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis
-
S. Dooley, I. Herlitzka, R. Hanselmann, A. Ermis, W. Henn, K. Remberger, T. Hopf, C. Welter, Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis, Ann. Rheum. Dis. 55 (1996) 298-304.
-
(1996)
Ann. Rheum. Dis.
, vol.55
, pp. 298-304
-
-
Dooley, S.1
Herlitzka, I.2
Hanselmann, R.3
Ermis, A.4
Henn, W.5
Remberger, K.6
Hopf, T.7
Welter, C.8
-
54
-
-
0030905825
-
Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium
-
H. Asahara, K. Fujisawa, T. Kobata, T. Hasunuma, T. Maeda, M. Asanuma, N. Ogawa, H. Inoue, T. Sumida, K. Nishioka, Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium, Arthritis Rheum. 40 (1997) 912-918.
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 912-918
-
-
Asahara, H.1
Fujisawa, K.2
Kobata, T.3
Hasunuma, T.4
Maeda, T.5
Asanuma, M.6
Ogawa, N.7
Inoue, H.8
Sumida, T.9
Nishioka, K.10
-
55
-
-
0030971406
-
Studies on the contribution of c-fos/AP-1 to arthritic joint destruction
-
S. Shiozawa, K. Shimizu, K. Tanaka, K. Hino, Studies on the contribution of c-fos/AP-1 to arthritic joint destruction, J. Clin. Invest. 99 (1997) 1210-1216.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1210-1216
-
-
Shiozawa, S.1
Shimizu, K.2
Tanaka, K.3
Hino, K.4
-
56
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
T. Taniguchi, K. Ogasawara, A. Takaoka, N. Tanaka, IRF family of transcription factors as regulators of host defense, Annu. Rev. Immunol. 19 (2001) 623-655.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 623-655
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
57
-
-
0031255318
-
The role of IFN regulatory factor-1 in synovitis and nitric oxide production
-
A. Shiraishi, J. Dudler, M. Lotz, The role of IFN regulatory factor-1 in synovitis and nitric oxide production, J. Immunol. 159 (1997) 3549-3554.
-
(1997)
J. Immunol.
, vol.159
, pp. 3549-3554
-
-
Shiraishi, A.1
Dudler, J.2
Lotz, M.3
-
58
-
-
0031048823
-
Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1
-
Y. Tada, A. Ho, T. Matsuyama, T.W. Mak, Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1, J. Exp. Med. 185 (1997) 231-238.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 231-238
-
-
Tada, Y.1
Ho, A.2
Matsuyama, T.3
Mak, T.W.4
-
59
-
-
0032970070
-
C/EBP beta in rheumatoid arthritis: Correlation with inflammation, not disease specificity
-
R.M. Pope, R. Lovis, S. Mungre, H. Perlman, A.E. Koch, G.K. Haines III, C/EBP beta in rheumatoid arthritis: correlation with inflammation, not disease specificity, Clin. Immunol. 91 (1999) 271-282.
-
(1999)
Clin. Immunol.
, vol.91
, pp. 271-282
-
-
Pope, R.M.1
Lovis, R.2
Mungre, S.3
Perlman, H.4
Koch, A.E.5
Haines III, G.K.6
-
60
-
-
0028282519
-
Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients
-
Erratum appears in J. Immunol.153 (1994 Dec 1)(11) 5347
-
W.K. Aicher, A.H. Heer, A. Trabandt, S.L. Bridges Jr., H.W. Schroeder Jr., G. Stransky, R.E. Gay, H. Eibel, H.H. Peter, U. Siebenlist, Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients, ((Erratum appears in J. Immunol.153 (1994 Dec 1)(11) 5347))J. Immunol. 152 (1994) 5940-5948.
-
(1994)
J. Immunol.
, vol.152
, pp. 5940-5948
-
-
Aicher, W.K.1
Heer, A.H.2
Trabandt, A.3
Bridges Jr., S.L.4
Schroeder Jr., H.W.5
Stransky, G.6
Gay, R.E.7
Eibel, H.8
Peter, H.H.9
Siebenlist, U.10
-
61
-
-
0035092527
-
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: Regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha
-
K. Redlich, H.P. Kiener, G. Schett, M. Tohidast-Akrad, E. Selzer, I. Radda, G.H. Stummvoll, C.W. Steiner, M. Groger, P. Bitzan, P. Zenz, J.S. Smolen, G. Steiner, Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha, Arthritis Rheum. 44 (2001) 266-274.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 266-274
-
-
Redlich, K.1
Kiener, H.P.2
Schett, G.3
Tohidast-Akrad, M.4
Selzer, E.5
Radda, I.6
Stummvoll, G.H.7
Steiner, C.W.8
Groger, M.9
Bitzan, P.10
Zenz, P.11
Smolen, J.S.12
Steiner, G.13
-
62
-
-
0034816301
-
Expression of ID family genes in the synovia from patients with rheumatoid arthritis
-
D. Sakurai, A. Yamaguchi, N. Tsuchiya, K. Yamamoto, K. Tokunaga, Expression of ID family genes in the synovia from patients with rheumatoid arthritis, Biochem. Biophys. Res. Commun. 284 (2001) 436-442.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 436-442
-
-
Sakurai, D.1
Yamaguchi, A.2
Tsuchiya, N.3
Yamamoto, K.4
Tokunaga, K.5
-
63
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
A.M. Reimold, N.N. Iwakoshi, J. Manis, P. Vallabhajosyula, E. Szomolanyi-Tsuda, E.M. Gravallese, D. Friend, M.J. Grusby, F. Alt, L.H. Glimcher, Plasma cell differentiation requires the transcription factor XBP-1, Nature 412 (2001) 300-307.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
Friend, D.7
Grusby, M.J.8
Alt, F.9
Glimcher, L.H.10
-
64
-
-
0027441514
-
Interleukin-2- and interferon-γ-secreting T cells in normal and diseased human intestinal mucosa
-
E. Breese, C.P. Braegger, C.J. Corrigan, J.A. Walker-Smith, T.T. MacDonald, Interleukin-2- and interferon-g-secreting T cells in normal and diseased human intestinal mucosa, Immunology 78 (1993) 127-131.
-
(1993)
Immunology
, vol.78
, pp. 127-131
-
-
Breese, E.1
Braegger, C.P.2
Corrigan, C.J.3
Walker-Smith, J.A.4
MacDonald, T.T.5
-
65
-
-
0028519015
-
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
-
F. Powrie, M.W. Leach, S. Mauze, S. Menon, L.B. Caddle, R.L. Coffman, Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells, Immunity 1 (1994) 553-562.
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Menon, S.4
Caddle, L.B.5
Coffman, R.L.6
-
66
-
-
0030209985
-
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
I.J. Fuss, M. Neurath, M. Boirivant, J.S. Klein, C. de la Motte, S.A. Strong, C. Fiocchi, W. Strober, Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-g, whereas ulcerative colitis LP cells manifest increased secretion of IL-5, J. Immunol. 157 (1996) 1261-1270.
-
(1996)
J. Immunol.
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
Klein, J.S.4
De La Motte, C.5
Strong, S.A.6
Fiocchi, C.7
Strober, W.8
-
67
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor a for Crohn's disease
-
Crohn's Disease cA2 Study Group
-
S.R. Targan, S.B. Hanauer, S.J. van Deventer, L. Mayer, D.H. Present, T. Braakman, K.L. DeWoody, T.F. Schaible, P.J. Rutgeerts, A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor a for Crohn's disease. Crohn's Disease cA2 Study Group, N. Engl. J. Med. 337 (1997) 1029-1035.
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
68
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
M.F. Neurath, I. Fuss, B.L. Kelsall, E. Stuber, W. Strober, Antibodies to interleukin 12 abrogate established experimental colitis in mice, J. Exp. Med. 182 (1995) 1281-1290.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
69
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
M.T. Wiekowski, M.W. Leach, E.W. Evans, L. Sullivan, S.C. Chen, G. Vassileva, J.F. Bazan, D.M. Gorman, R.A. Kastelein, S. Narula, S.A. Lira, Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death, J. Immunol. 166 (2001) 7563-7570.
-
(2001)
J. Immunol.
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
Bazan, J.F.7
Gorman, D.M.8
Kastelein, R.A.9
Narula, S.10
Lira, S.A.11
-
70
-
-
0033168120
-
Bioactive IL-18 expression is up-regulated in Crohn's disease
-
G. Monteleone, F. Trapasso, T. Parrello, L. Biancone, A. Stella, R. Iuliano, F. Luzza, A. Fusco, F. Pallone, Bioactive IL-18 expression is up-regulated in Crohn's disease, J. Immunol. 163 (1999) 143-147.
-
(1999)
J. Immunol.
, vol.163
, pp. 143-147
-
-
Monteleone, G.1
Trapasso, F.2
Parrello, T.3
Biancone, L.4
Stella, A.5
Iuliano, R.6
Luzza, F.7
Fusco, A.8
Pallone, F.9
-
71
-
-
0033152023
-
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
-
T.T. Pizarro, M.H. Michie, M. Bentz, J. Woraratanadharm, M.F. Smith Jr., E. Foley, C.A. Moskaluk, S.J. Bickston, F. Cominelli, IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells, J. Immunol. 162 (1999) 6829-6835.
-
(1999)
J. Immunol.
, vol.162
, pp. 6829-6835
-
-
Pizarro, T.T.1
Michie, M.H.2
Bentz, M.3
Woraratanadharm, J.4
Smith Jr., M.F.5
Foley, E.6
Moskaluk, C.A.7
Bickston, S.J.8
Cominelli, F.9
-
72
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
M.F. Neurath, S. Pettersson, K.H. Meyer zum Buschenfelde, W. Strober, Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice, Nat. Med. 2 (1996) 998-1004.
-
(1996)
Nat. Med.
, vol.2
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer Zum Buschenfelde, K.H.3
Strober, W.4
-
73
-
-
0031723007
-
Activation of nuclear factor κB in Crohn's disease
-
R.D. Ellis, J.R. Goodlad, G.A. Limb, J.J. Powell, R.P. Thompson, N.A. Punchard, Activation of nuclear factor κB in Crohn's disease, Inflammation Res. 47 (1998) 440-445.
-
(1998)
Inflammation Res.
, vol.47
, pp. 440-445
-
-
Ellis, R.D.1
Goodlad, J.R.2
Limb, G.A.3
Powell, J.J.4
Thompson, R.P.5
Punchard, N.A.6
-
74
-
-
0032437063
-
Cytokine gene transcription by NF-κB family members in patients with inflammatory bowel disease
-
M.F. Neurath, I. Fuss, G. Schurmann, S. Pettersson, K. Arnold, H. Muller-Lobeck, W. Strober, C. Herfarth, K.H. Buschenfelde, Cytokine gene transcription by NF-κB family members in patients with inflammatory bowel disease, Ann. N. Y. Acad. Sci. 859 (1998) 149-159.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.859
, pp. 149-159
-
-
Neurath, M.F.1
Fuss, I.2
Schurmann, G.3
Pettersson, S.4
Arnold, K.5
Muller-Lobeck, H.6
Strober, W.7
Herfarth, C.8
Buschenfelde, K.H.9
-
75
-
-
0031595210
-
Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa
-
G. Rogler, K. Brand, D. Vogl, S. Page, R. Hofmeister, T. Andus, R. Knuechel, P.A. Baeuerle, J. Scholmerich, V. Gross, Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa, Gastroenterology 115 (1998) 357-369.
-
(1998)
Gastroenterology
, vol.115
, pp. 357-369
-
-
Rogler, G.1
Brand, K.2
Vogl, D.3
Page, S.4
Hofmeister, R.5
Andus, T.6
Knuechel, R.7
Baeuerle, P.A.8
Scholmerich, J.9
Gross, V.10
-
76
-
-
0037789455
-
Nuclear factor κB is activated in small intestinal mucosa of celiac patients
-
M.C. Maiuri, D. De Stefano, G. Mele, S. Fecarotta, L. Greco, R. Troncone, R. Carnuccio, Nuclear factor κB is activated in small intestinal mucosa of celiac patients, J. Mol. Med. 81 (2003) 373-379.
-
(2003)
J. Mol. Med.
, vol.81
, pp. 373-379
-
-
Maiuri, M.C.1
De Stefano, D.2
Mele, G.3
Fecarotta, S.4
Greco, L.5
Troncone, R.6
Carnuccio, R.7
-
77
-
-
0031932422
-
Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells
-
C. Jobin, A. Panja, C. Hellerbrand, Y. Iimuro, J. Didonato, D.A. Brenner, R.B. Sartor, Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells, J. Immunol. 160 (1998) 410-418.
-
(1998)
J. Immunol.
, vol.160
, pp. 410-418
-
-
Jobin, C.1
Panja, A.2
Hellerbrand, C.3
Iimuro, Y.4
Didonato, J.5
Brenner, D.A.6
Sartor, R.B.7
-
78
-
-
0031808369
-
Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors
-
C. Jobin, C. Hellerbrand, L.L. Licato, D.A. Brenner, R.B. Sartor, Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors, Gut 42 (1998) 779-787.
-
(1998)
Gut
, vol.42
, pp. 779-787
-
-
Jobin, C.1
Hellerbrand, C.2
Licato, L.L.3
Brenner, D.A.4
Sartor, R.B.5
-
79
-
-
0030636792
-
Evidence for altered regulation of IκBα degradation in human colonic epithelial cells
-
C. Jobin, S. Haskill, L. Mayer, A. Panja, R.B. Sartor, Evidence for altered regulation of InBa degradation in human colonic epithelial cells, J. Immunol. 158 (1997) 226-234.
-
(1997)
J. Immunol.
, vol.158
, pp. 226-234
-
-
Jobin, C.1
Haskill, S.2
Mayer, L.3
Panja, A.4
Sartor, R.B.5
-
80
-
-
18444395237
-
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-κB transcription factors
-
D.A. van Heel, I.A. Udalova, A.P. De Silva, D.P. McGovern, Y. Kinouchi, J. Hull, N.J. Lench, L.R. Cardon, A.H. Carey, D.P. Jewell, D. Kwiatkowski, Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-κB transcription factors, Hum. Mol. Genet. 11 (2002) 1281-1289.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1281-1289
-
-
Van Heel, D.A.1
Udalova, I.A.2
De Silva, A.P.3
McGovern, D.P.4
Kinouchi, Y.5
Hull, J.6
Lench, N.J.7
Cardon, L.R.8
Carey, A.H.9
Jewell, D.P.10
Kwiatkowski, D.11
-
81
-
-
0033863238
-
Butyrate inhibits inflammatory responses through NFκB inhibition: Implications for Crohn's disease
-
J.P. Segain, D. Raingeard de la Bletiere, A. Bourreille, V. Leray, N. Gervois, C. Rosales, L. Ferrier, C. Bonnet, H.M. Blottiere, J.P. Galmiche, Butyrate inhibits inflammatory responses through NFκB inhibition: implications for Crohn's disease, Gut 47 (2000) 397-403.
-
(2000)
Gut
, vol.47
, pp. 397-403
-
-
Segain, J.P.1
Raingeard De La Bletiere, D.2
Bourreille, A.3
Leray, V.4
Gervois, N.5
Rosales, C.6
Ferrier, L.7
Bonnet, C.8
Blottiere, H.M.9
Galmiche, J.P.10
-
82
-
-
0034124076
-
Therapeutic effect of intracolonically administered nuclear factor (B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis
-
M. Murano, K. Maemura, I. Hirata, K. Toshina, T. Nishikawa, N. Hamamoto, S. Sasaki, O. Saitoh, K. Katsu, Therapeutic effect of intracolonically administered nuclear factor (B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis, Clin. Exp. Immunol. 120 (2000) 51-58.
-
(2000)
Clin. Exp. Immunol.
, vol.120
, pp. 51-58
-
-
Murano, M.1
Maemura, K.2
Hirata, I.3
Toshina, K.4
Nishikawa, T.5
Hamamoto, N.6
Sasaki, S.7
Saitoh, O.8
Katsu, K.9
-
83
-
-
0034671633
-
Up-regulation of the IL-12 receptor β2 chain in Crohn's disease
-
T. Parrello, G. Monteleone, S. Cucchiara, I. Monteleone, L. Sebkova, P. Doldo, F. Luzza, F. Pallone, Up-regulation of the IL-12 receptor β2 chain in Crohn's disease, J. Immunol. 165 (2000) 7234-7239.
-
(2000)
J. Immunol.
, vol.165
, pp. 7234-7239
-
-
Parrello, T.1
Monteleone, G.2
Cucchiara, S.3
Monteleone, I.4
Sebkova, L.5
Doldo, P.6
Luzza, F.7
Pallone, F.8
-
84
-
-
0035070596
-
Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis
-
T. Kuhbacher, P. Gionchetti, J. Hampe, U. Helwig, P. Rosenstiel, M. Campieri, H.J. Buhr, S. Schreiber, Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis, Clin. Exp. Immunol. 123 (2001) 395-401.
-
(2001)
Clin. Exp. Immunol.
, vol.123
, pp. 395-401
-
-
Kuhbacher, T.1
Gionchetti, P.2
Hampe, J.3
Helwig, U.4
Rosenstiel, P.5
Campieri, M.6
Buhr, H.J.7
Schreiber, S.8
-
85
-
-
0034843855
-
Interferon-α drives T cell-mediated immunopathology in the intestine
-
G. Monteleone, S.L. Pender, N.C. Wathen, T.T. MacDonald, Interferon-α drives T cell-mediated immunopathology in the intestine, Eur. J. Immunol. 31 (2001) 2247-2255.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2247-2255
-
-
Monteleone, G.1
Pender, S.L.2
Wathen, N.C.3
MacDonald, T.T.4
-
86
-
-
0036716702
-
Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease
-
S. Schreiber, P. Rosenstiel, J. Hampe, S. Nikolaus, B. Groessner, A. Schottelius, T. Kuhbacher, J. Hamling, U.R. Folsch, D. Seegert, Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease, Gut 51 (2002) 379-385.
-
(2002)
Gut
, vol.51
, pp. 379-385
-
-
Schreiber, S.1
Rosenstiel, P.2
Hampe, J.3
Nikolaus, S.4
Groessner, B.5
Schottelius, A.6
Kuhbacher, T.7
Hamling, J.8
Folsch, U.R.9
Seegert, D.10
-
87
-
-
0038269009
-
Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
-
P. Lovato, C. Brender, J. Agnholt, J. Kelsen, K. Kaltoft, A. Svejgaard, K.W. Eriksen, A. Woetmann, N. Odum, Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease, J. Biol. Chem. 278 (2003) 16777-16781.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16777-16781
-
-
Lovato, P.1
Brender, C.2
Agnholt, J.3
Kelsen, J.4
Kaltoft, K.5
Svejgaard, A.6
Eriksen, K.W.7
Woetmann, A.8
Odum, N.9
-
88
-
-
0037568363
-
Constitutive activation of the signal transducer and activator of transcription pathway in celiac disease lesions
-
G. Mazzarella, T.T. MacDonald, V.M. Salvati, P. Mulligan, L. Pasquale, R. Stefanile, P. Lionetti, S. Auricchio, F. Pallone, R. Troncone, G. Monteleone, Constitutive activation of the signal transducer and activator of transcription pathway in celiac disease lesions, Am. J. Pathol. 162 (2003) 1845-1855.
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1845-1855
-
-
Mazzarella, G.1
MacDonald, T.T.2
Salvati, V.M.3
Mulligan, P.4
Pasquale, L.5
Stefanile, R.6
Lionetti, P.7
Auricchio, S.8
Pallone, F.9
Troncone, R.10
Monteleone, G.11
-
89
-
-
0032550312
-
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon γ expression by T cells
-
S.J. Simpson, S. Shah, M. Comiskey, Y.P. de Jong, B. Wang, E. Mizoguchi, A.K. Bhan, C. Terhorst, T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon γ expression by T cells, J. Exp. Med. 187 (1998) 1225-1234.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1225-1234
-
-
Simpson, S.J.1
Shah, S.2
Comiskey, M.3
De Jong, Y.P.4
Wang, B.5
Mizoguchi, E.6
Bhan, A.K.7
Terhorst, C.8
-
90
-
-
0033558364
-
Cutting edge: Chronic intestinal inflammation in STAT-4 transgenic mice: Characterization of disease and adoptive transfer by TNF-plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens
-
S. Wirtz, S. Finotto, S. Kanzler, A.W. Lohse, M. Blessing, H.A. Lehr, P.R. Galle, M.F. Neurath, Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF-plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens, J. Immunol. 162 (1999) 1884-1888.
-
(1999)
J. Immunol.
, vol.162
, pp. 1884-1888
-
-
Wirtz, S.1
Finotto, S.2
Kanzler, S.3
Lohse, A.W.4
Blessing, M.5
Lehr, H.A.6
Galle, P.R.7
Neurath, M.F.8
-
91
-
-
0037452789
-
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
-
T. Welte, S.S. Zhang, T. Wang, Z. Zhang, D.G. Hesslein, Z. Yin, A. Kano, Y. Iwamoto, E. Li, J.E. Craft, A.L. Bothwell, E. Fikrig, P.A. Koni, R.A. Flavell, X.Y. Fu, STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity, Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 1879-1884.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1879-1884
-
-
Welte, T.1
Zhang, S.S.2
Wang, T.3
Zhang, Z.4
Hesslein, D.G.5
Yin, Z.6
Kano, A.7
Iwamoto, Y.8
Li, E.9
Craft, J.E.10
Bothwell, A.L.11
Fikrig, E.12
Koni, P.A.13
Flavell, R.A.14
Fu, X.Y.15
-
92
-
-
0037338992
-
Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease
-
B. Xia, J.B. Crusius, J. Wu, A. Zwiers, A.A. van Bodegraven, A.S. Pena, Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease, Clin. Exp. Immunol. 131 (2003) 446-450.
-
(2003)
Clin. Exp. Immunol.
, vol.131
, pp. 446-450
-
-
Xia, B.1
Crusius, J.B.2
Wu, J.3
Zwiers, A.4
Van Bodegraven, A.A.5
Pena, A.S.6
-
93
-
-
0141630493
-
The role of signal transducers and activators of transcription in T inflammatory bowel diseases
-
J. Mudter, M.F. Neurath, The role of signal transducers and activators of transcription in T inflammatory bowel diseases, Inflammatory Bowel Dis. 9 (2003) 332-337.
-
(2003)
Inflammatory Bowel Dis.
, vol.9
, pp. 332-337
-
-
Mudter, J.1
Neurath, M.F.2
-
94
-
-
0033119649
-
T-box genes: What they do and how they do it
-
J. Smith, T-box genes: what they do and how they do it, Trends Genet. 15 (1999) 154-158.
-
(1999)
Trends Genet.
, vol.15
, pp. 154-158
-
-
Smith, J.1
-
95
-
-
0037117557
-
T-bet regulates IgG class switching and pathogenic autoantibody production
-
S.L. Peng, S.J. Szabo, L.H. Glimcher, T-bet regulates IgG class switching and pathogenic autoantibody production, Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 5545-5550.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5545-5550
-
-
Peng, S.L.1
Szabo, S.J.2
Glimcher, L.H.3
-
96
-
-
0037059462
-
Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
-
S.J. Szabo, B.M. Sullivan, C. Stemmann, A.R. Satoskar, B.P. Sleckman, L.H. Glimcher, Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells, Science 295 (2002) 338-342.
-
(2002)
Science
, vol.295
, pp. 338-342
-
-
Szabo, S.J.1
Sullivan, B.M.2
Stemmann, C.3
Satoskar, A.R.4
Sleckman, B.P.5
Glimcher, L.H.6
-
97
-
-
0037934497
-
T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells
-
G. Lugo-Villarino, R. Maldonado-Lopez, R. Possemato, C. Penaranda, L.H. Glimcher, T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells, Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 7749-7754.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7749-7754
-
-
Lugo-Villarino, G.1
Maldonado-Lopez, R.2
Possemato, R.3
Penaranda, C.4
Glimcher, L.H.5
-
98
-
-
0034094867
-
Detection of interferon regulatory factor-1 in lamina propria mononuclear cells in Crohn's disease
-
M. Clavell, H. Correa-Gracian, Z. Liu, R. Craver, R. Brown, E. Schmidt-Sommerfeld , J. Udall Jr., A. Delgado, E. Mannick, Detection of interferon regulatory factor-1 in lamina propria mononuclear cells in Crohn's disease, J. Pediatr. Gastroenterol. Nutr. 30 (2000) 43-47.
-
(2000)
J. Pediatr. Gastroenterol. Nutr.
, vol.30
, pp. 43-47
-
-
Clavell, M.1
Correa-Gracian, H.2
Liu, Z.3
Craver, R.4
Brown, R.5
Schmidt-Sommerfeld, E.6
Udall Jr., J.7
Delgado, A.8
Mannick, E.9
-
99
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Erratum appears in J. Exp. Med. 195 (2002 Jun 3)(11) 1513
-
M.F. Neurath, B. Weigmann, S. Finotto, J. Glickman, E. Nieuwenhuis, H. Iijima, A. Mizoguchi, E. Mizoguchi, J. Mudter, P.R. Galle, A. Bhan, F. Autschbach, B.M. Sullivan, S.J. Szabo, L.H. Glimcher, R.S. Blumberg, The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease, (Erratum appears in J. Exp. Med. 195 (2002 Jun 3)(11) 1513), J. Exp. Med. 195 (2002) 1129-1143.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1129-1143
-
-
Neurath, M.F.1
Weigmann, B.2
Finotto, S.3
Glickman, J.4
Nieuwenhuis, E.5
Iijima, H.6
Mizoguchi, A.7
Mizoguchi, E.8
Mudter, J.9
Galle, P.R.10
Bhan, A.11
Autschbach, F.12
Sullivan, B.M.13
Szabo, S.J.14
Glimcher, L.H.15
Blumberg, R.S.16
-
100
-
-
0036155753
-
Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease
-
V.M. Salvati, T.T. MacDonald, M. Bajaj-Elliott, M. Borrelli, A. Staiano, S. Auricchio, R. Troncone, G. Monteleone, Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease, Gut 50 (2002) 186-190.
-
(2002)
Gut
, vol.50
, pp. 186-190
-
-
Salvati, V.M.1
MacDonald, T.T.2
Bajaj-Elliott, M.3
Borrelli, M.4
Staiano, A.5
Auricchio, S.6
Troncone, R.7
Monteleone, G.8
-
101
-
-
0037013930
-
Mechanism of transforming growth factor b-induced inhibition of T helper type 1 differentiation
-
L. Gorelik, S. Constant, R.A. Flavell, Mechanism of transforming growth factor b-induced inhibition of T helper type 1 differentiation, J. Exp. Med. 195 (2002) 1499-1505.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
102
-
-
0033330911
-
Clinical review 103: T helper type 1 and 2 cytokines mediate the onset and progression of type I (insulin-dependent) diabetes
-
W.Y. Almawi, H. Tamim, S.T. Azar, Clinical review 103: T helper type 1 and 2 cytokines mediate the onset and progression of type I (insulin-dependent) diabetes, J. Clin. Endocrinol. Metab. 84 (1999) 1497-1502.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1497-1502
-
-
Almawi, W.Y.1
Tamim, H.2
Azar, S.T.3
-
103
-
-
0036137987
-
Understanding autoimmune diabetes: Insights from mouse models
-
L. Adorini, S. Gregori, L.C. Harrison, Understanding autoimmune diabetes: insights from mouse models, Trends Mol. Med. 8 (2002) 31-38.
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 31-38
-
-
Adorini, L.1
Gregori, S.2
Harrison, L.C.3
-
104
-
-
0035656173
-
Diabetes-associated sustained activation of the transcription factor nuclear factor-κB
-
A. Bierhaus, S. Schiekofer, M. Schwaninger, M. Andrassy, P.M. Humpert, J. Chen, M. Hong, T. Luther, T. Henle, I. Kloting, M. Morcos, M. Hofmann, H. Tritschler, B.Weigle, M. Kasper,M. Smith, G. Perry, A.M. Schmidt, D.M. Stern, H.U. Haring, E. Schleicher, P.P. Nawroth, Diabetes-associated sustained activation of the transcription factor nuclear factor-κB, Diabetes 50 (2001) 2792-2808.
-
(2001)
Diabetes
, vol.50
, pp. 2792-2808
-
-
Bierhaus, A.1
Schiekofer, S.2
Schwaninger, M.3
Andrassy, M.4
Humpert, P.M.5
Chen, J.6
Hong, M.7
Luther, T.8
Henle, T.9
Kloting, I.10
Morcos, M.11
Hofmann, M.12
Tritschler, H.13
Weigle, B.14
Kasper, M.15
Smith, M.16
Perry, G.17
Schmidt, A.M.18
Stern, D.M.19
Haring, H.U.20
Schleicher, E.21
Nawroth, P.P.22
more..
-
105
-
-
0035424898
-
Dendritic cells from nonobese diabetic mice exhibit a defect in NF-κB regulation due to a hyperactive IκB kinase
-
D.J. Weaver Jr., B. Poligone, T. Bui, U.M. Abdel-Motal, A.S. Baldwin Jr., R. Tisch, Dendritic cells from nonobese diabetic mice exhibit a defect in NF-κB regulation due to a hyperactive IκB kinase, J. Immunol. 167 (2001) 1461-1468.
-
(2001)
J. Immunol.
, vol.167
, pp. 1461-1468
-
-
Weaver Jr., D.J.1
Poligone, B.2
Bui, T.3
Abdel-Motal, U.M.4
Baldwin Jr., A.S.5
Tisch, R.6
-
106
-
-
0036006693
-
Elevated NF-κB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function
-
B. Poligone, D.J. Weaver Jr., P. Sen, A.S. Baldwin Jr., R. Tisch, Elevated NF-κB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function, J. Immunol. 168 (2002) 188-196.
-
(2002)
J. Immunol.
, vol.168
, pp. 188-196
-
-
Poligone, B.1
Weaver Jr., D.J.2
Sen, P.3
Baldwin Jr., A.S.4
Tisch, R.5
-
107
-
-
0037408257
-
Distinct pathways for NF-κB regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains
-
J. Liu, D.I. Beller, Distinct pathways for NF-κB regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains, J. Immunol. 170 (2003) 4489-4496.
-
(2003)
J. Immunol.
, vol.170
, pp. 4489-4496
-
-
Liu, J.1
Beller, D.I.2
-
108
-
-
0033499621
-
NOD mice are defective in proteasome production and activation of NF-κB
-
T. Hayashi, D. Faustman, NOD mice are defective in proteasome production and activation of NF-κB, Mol. Cell. Biol. 19 (1999) 8646-8659.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8646-8659
-
-
Hayashi, T.1
Faustman, D.2
-
109
-
-
0035983492
-
NFκB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes
-
J.G. Mabley, G. Hasko, L. Liaudet, F. Soriano, G.J. Southan, A.L. Salzman, C. Szabo, NFκB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes, J. Endocrinol. 173 (2002) 457-464.
-
(2002)
J. Endocrinol.
, vol.173
, pp. 457-464
-
-
Mabley, J.G.1
Hasko, G.2
Liaudet, L.3
Soriano, F.4
Southan, G.J.5
Salzman, A.L.6
Szabo, C.7
-
110
-
-
0142241399
-
Transcriptional regulation of type I diabetes by NF-κB
-
S.-E. Lamhamedi-Cherradi, S. Zheng, B.A. Hilliard, L. Xu, J. Sun, S. Alsheadat, H.-C. Liou, Y.H. Chen, Transcriptional regulation of type I diabetes by NF-κB, J. Immunol. 171 (2003) 4886-4892.
-
(2003)
J. Immunol.
, vol.171
, pp. 4886-4892
-
-
Lamhamedi-Cherradi, S.-E.1
Zheng, S.2
Hilliard, B.A.3
Xu, L.4
Sun, J.5
Alsheadat, S.6
Liou, H.-C.7
Chen, Y.H.8
-
111
-
-
0042767606
-
Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity
-
L. Ma, S. Qian, X. Liang, L. Wang, J.E. Woodward, N. Giannoukakis, P.D. Robbins, S. Bertera, M. Trucco, J.J. Fung, L. Lu, Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity, Diabetes 52 (2003) 1976-1985.
-
(2003)
Diabetes
, vol.52
, pp. 1976-1985
-
-
Ma, L.1
Qian, S.2
Liang, X.3
Wang, L.4
Woodward, J.E.5
Giannoukakis, N.6
Robbins, P.D.7
Bertera, S.8
Trucco, M.9
Fung, J.J.10
Lu, L.11
-
112
-
-
0035487255
-
NFκB polymorphisms and susceptibility to type 1 diabetes
-
D.M. Hegazy, D.A. O'Reilly, B.M. Yang, A.D. Hodgkinson, B.A. Millward, A.G. Demaine, NFκB polymorphisms and susceptibility to type 1 diabetes, Genes Immun. 2 (2001) 304-308.
-
(2001)
Genes Immun.
, vol.2
, pp. 304-308
-
-
Hegazy, D.M.1
O'Reilly, D.A.2
Yang, B.M.3
Hodgkinson, A.D.4
Millward, B.A.5
Demaine, A.G.6
-
113
-
-
0346154591
-
Characterization of a nuclear-factor-κB (NFκB) genetic marker in type 1 diabetes (T1DM) families
-
T. Gylvin, R. Bergholdt, J. Nerup, F. Pociot, Characterization of a nuclear-factor-κB (NFκB) genetic marker in type 1 diabetes (T1DM) families, Genes Immun. 3 (2002) 430-432.
-
(2002)
Genes Immun.
, vol.3
, pp. 430-432
-
-
Gylvin, T.1
Bergholdt, R.2
Nerup, J.3
Pociot, F.4
-
114
-
-
0035313059
-
IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic β cell death
-
K. Suk, S. Kim, Y.H. Kim, K.A. Kim, I. Chang, H. Yagita, M. Shong, M.S. Lee, IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic β cell death, J. Immunol. 166 (2001) 4481-4489.
-
(2001)
J. Immunol.
, vol.166
, pp. 4481-4489
-
-
Suk, K.1
Kim, S.2
Kim, Y.H.3
Kim, K.A.4
Chang, I.5
Yagita, H.6
Shong, M.7
Lee, M.S.8
-
115
-
-
0037094032
-
Molecular mechanisms for gender differences in susceptibility to T cell-mediated autoimmune diabetes in nonobese diabetic mice
-
M. Bao, Y. Yang, H.S. Jun, J.W. Yoon, Molecular mechanisms for gender differences in susceptibility to T cell-mediated autoimmune diabetes in nonobese diabetic mice, J. Immunol. 168 (2002) 5369-5375.
-
(2002)
J. Immunol.
, vol.168
, pp. 5369-5375
-
-
Bao, M.1
Yang, Y.2
Jun, H.S.3
Yoon, J.W.4
-
116
-
-
0345422708
-
Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence
-
A. Holz, A. Bot, B. Coon, T. Wolfe, M.J. Grusby, M.G. von Herrath, Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence, J. Immunol. 163 (1999) 5374-5382.
-
(1999)
J. Immunol.
, vol.163
, pp. 5374-5382
-
-
Holz, A.1
Bot, A.2
Coon, B.3
Wolfe, T.4
Grusby, M.J.5
Von Herrath, M.G.6
-
117
-
-
0033213471
-
Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway
-
D. Homann, A. Holz, A. Bot, B. Coon, T. Wolfe, J. Petersen, T.P. Dyrberg, M.J. Grusby, M.G. von Herrath, Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway, Immunity 11 (1999) 463-472.
-
(1999)
Immunity
, vol.11
, pp. 463-472
-
-
Homann, D.1
Holz, A.2
Bot, A.3
Coon, B.4
Wolfe, T.5
Petersen, J.6
Dyrberg, T.P.7
Grusby, M.J.8
Von Herrath, M.G.9
-
118
-
-
0035444577
-
Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1
-
T. Nakazawa, J. Satoh, K. Takahashi, Y. Sakata, F. Ikehata, Y. Takizawa, S.I. Bando, T. Housai, Y. Li, C. Chen, T. Masuda, S. Kure, I. Kato, S. Takasawa, T. Taniguchi, H. Okamoto, T. Toyota, Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1, J. Autoimmun. 17 (2001) 119-125.
-
(2001)
J. Autoimmun.
, vol.17
, pp. 119-125
-
-
Nakazawa, T.1
Satoh, J.2
Takahashi, K.3
Sakata, Y.4
Ikehata, F.5
Takizawa, Y.6
Bando, S.I.7
Housai, T.8
Li, Y.9
Chen, C.10
Masuda, T.11
Kure, S.12
Kato, I.13
Takasawa, S.14
Taniguchi, T.15
Okamoto, H.16
Toyota, T.17
-
119
-
-
0030678477
-
No association or linkage to IDDM of an interferon regulatory factor-1 gene polymorphism in a Danish population
-
The Danish Study Group for Diabetes in Childhood
-
J. Johannesen, A.E. Karlsen, J. Nerup, F. Pociot, No association or linkage to IDDM of an interferon regulatory factor-1 gene polymorphism in a Danish population. The Danish Study Group for Diabetes in Childhood, Eur. J. Immunogenet. 24 (1997) 377-383.
-
(1997)
Eur. J. Immunogenet.
, vol.24
, pp. 377-383
-
-
Johannesen, J.1
Karlsen, A.E.2
Nerup, J.3
Pociot, F.4
-
120
-
-
0035156871
-
Variable effects of transgenic c-Maf on autoimmune diabetes
-
M.E. Pauza, A. Nguyen, T. Wolfe, I.C. Ho, L.H. Glimcher, M. von Herrath, D. Lo, Variable effects of transgenic c-Maf on autoimmune diabetes, Diabetes 50 (2001) 39-46.
-
(2001)
Diabetes
, vol.50
, pp. 39-46
-
-
Pauza, M.E.1
Nguyen, A.2
Wolfe, T.3
Ho, I.C.4
Glimcher, L.H.5
Von Herrath, M.6
Lo, D.7
-
121
-
-
0025246367
-
The T lymphocyte in experimental allergic encephalomyelitis
-
S.S. Zamvil, L. Steinman, The T lymphocyte in experimental allergic encephalomyelitis, Annu. Rev. Immunol. 8 (1990) 579-621.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 579-621
-
-
Zamvil, S.S.1
Steinman, L.2
-
122
-
-
0028990468
-
Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis
-
T. Olsson, Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis, Immunol. Rev. 144 (1995) 245-268.
-
(1995)
Immunol. Rev.
, vol.144
, pp. 245-268
-
-
Olsson, T.1
-
123
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
D.J. Cua, J. Sherlock, Y. Chen, C.A. Murphy, B. Joyce, B. Seymour, L. Lucian, W. To, S. Kwan, T. Churakova, S. Zurawski, M. Wiekowski, S.A. Lira, D. Gorman, R.A. Kastelein, J.D. Sedgwick, Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain, Nature 421 (2003) 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
124
-
-
0030587910
-
IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
D.O. Willenborg, S. Fordham, C.C. Bernard, W.B. Cowden, I.A. Ramshaw, IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis, J. Immunol. 157 (1996) 3223-3227.
-
(1996)
J. Immunol.
, vol.157
, pp. 3223-3227
-
-
Willenborg, D.O.1
Fordham, S.2
Bernard, C.C.3
Cowden, W.B.4
Ramshaw, I.A.5
-
125
-
-
0028172144
-
Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis
-
C. Kaltschmidt, B. Kaltschmidt, J. Lannes-Vieira, G.W. Kreutzberg, H. Wekerle, P.A. Baeuerle, J. Gehrmann, Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis, J. Neuroimmunol. 55 (1994) 99-106.
-
(1994)
J. Neuroimmunol.
, vol.55
, pp. 99-106
-
-
Kaltschmidt, C.1
Kaltschmidt, B.2
Lannes-Vieira, J.3
Kreutzberg, G.W.4
Wekerle, H.5
Baeuerle, P.A.6
Gehrmann, J.7
-
126
-
-
0031951041
-
Transcription factor NF-κB and inhibitor IκBα are localized in macrophages in active multiple sclerosis lesions
-
D. Gveric, C. Kaltschmidt, M.L. Cuzner, J. Newcombe, Transcription factor NF-κB and inhibitor IκBα are localized in macrophages in active multiple sclerosis lesions, J. Neuropathol. Exp. Neurol. 57 (1998) 168-178.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 168-178
-
-
Gveric, D.1
Kaltschmidt, C.2
Cuzner, M.L.3
Newcombe, J.4
-
127
-
-
0032589563
-
Activation of NF-κB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology
-
B. Bonetti, C. Stegagno, B. Cannella, N. Rizzuto, G. Moretto, C.S. Raine, Activation of NF-κB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology, Am. J. Pathol. 155 (1999) 1433-1438.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1433-1438
-
-
Bonetti, B.1
Stegagno, C.2
Cannella, B.3
Rizzuto, N.4
Moretto, G.5
Raine, C.S.6
-
128
-
-
0034674520
-
Activation of nuclear factor-κB in the spinal cord of experimental allergic encephalomyelitis
-
K. Pahan, M. Schmid, Activation of nuclear factor-κB in the spinal cord of experimental allergic encephalomyelitis, Neurosci. Lett. 287 (2000) 17-20.
-
(2000)
Neurosci. Lett.
, vol.287
, pp. 17-20
-
-
Pahan, K.1
Schmid, M.2
-
129
-
-
0034800712
-
Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesions
-
S.J. Gobin, L. Montagne, M. Van Zutphen, P. Van Der Valk, P.J. Van Den Elsen, C.J. De Groot, Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesions, Glia 36 (2001) 68-77.
-
(2001)
Glia
, vol.36
, pp. 68-77
-
-
Gobin, S.J.1
Montagne, L.2
Van Zutphen, M.3
Van Der Valk, P.4
Van Den Elsen, P.J.5
De Groot, C.J.6
-
130
-
-
0033198141
-
Experimental autoimmune encephalomyelitis in NF-κB-deficient mice:roles of NF-κB in the activation and differentiation of autoreactive T cells
-
B. Hilliard, E.B. Samoilova, T.S. Liu, A. Rostami, Y. Chen, Experimental autoimmune encephalomyelitis in NF-κB-deficient mice:roles of NF-κB in the activation and differentiation of autoreactive T cells, J. Immunol. 163 (1999) 2937-2943.
-
(1999)
J. Immunol.
, vol.163
, pp. 2937-2943
-
-
Hilliard, B.1
Samoilova, E.B.2
Liu, T.S.3
Rostami, A.4
Chen, Y.5
-
131
-
-
0036738421
-
Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation
-
B.A. Hilliard, N. Mason, L. Xu, J. Sun, S.E. Lamhamedi-Cherradi, H.C. Liou, C. Hunter, Y.H. Chen, Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation, J. Clin. Invest. 110 (2002) 843-850.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 843-850
-
-
Hilliard, B.A.1
Mason, N.2
Xu, L.3
Sun, J.4
Lamhamedi-Cherradi, S.E.5
Liou, H.C.6
Hunter, C.7
Chen, Y.H.8
-
132
-
-
0036615454
-
Inhibitors in the NFκB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations
-
B. Miterski, S. Bohringer, W. Klein, E. Sindern, M. Haupts, S. Schimrigk, J.T. Epplen, Inhibitors in the NFκB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations, Genes Immun. 3 (2002) 211-219.
-
(2002)
Genes Immun.
, vol.3
, pp. 211-219
-
-
Miterski, B.1
Bohringer, S.2
Klein, W.3
Sindern, E.4
Haupts, M.5
Schimrigk, S.6
Epplen, J.T.7
-
133
-
-
0035283411
-
STAT expression and localization in the central nervous system during autoimmune encephalomyelitis in Lewis rats
-
Y. Jee, G. Kim, N. Tanuma, Y. Matsumoto, STAT expression and localization in the central nervous system during autoimmune encephalomyelitis in Lewis rats, J. Neuroimmunol. 114 (2001) 40-47.
-
(2001)
J. Neuroimmunol.
, vol.114
, pp. 40-47
-
-
Jee, Y.1
Kim, G.2
Tanuma, N.3
Matsumoto, Y.4
-
134
-
-
0036142847
-
Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis
-
J. Maier, C. Kincaid, A. Pagenstecher, I.L. Campbell, Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis, Am. J. Pathol. 160 (2002) 271-288.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 271-288
-
-
Maier, J.1
Kincaid, C.2
Pagenstecher, A.3
Campbell, I.L.4
-
135
-
-
0034789247
-
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
-
T. Chitnis, N. Najafian, C. Benou, A.D. Salama, M.J. Grusby, M.H. Khoury, S.J. Khoury, Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis, J. Clin. Invest. 108 (2001) 739-747.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 739-747
-
-
Chitnis, T.1
Najafian, N.2
Benou, C.3
Salama, A.D.4
Grusby, M.J.5
Sayegh, M.H.6
Khoury, S.J.7
-
136
-
-
0037097660
-
Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes
-
C. Natarajan, J.J. Bright, Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes, J. Immunol. 168 (2002) 6506-6513.
-
(2002)
J. Immunol.
, vol.168
, pp. 6506-6513
-
-
Natarajan, C.1
Bright, J.J.2
-
137
-
-
0037058986
-
STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-α in the central nervous system
-
J.Wang, R.D. Schreiber, I.L. Campbell, STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-α in the central nervous system, Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 16209-16214.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 16209-16214
-
-
Wang, J.1
Schreiber, R.D.2
Campbell, I.L.3
-
138
-
-
0036341053
-
Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1
-
X. Feng, A.L. Petraglia, M. Chen, P.V. Byskosh, M.D. Boos, A.T. Reder, Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1, J. Neuroimmunol. 129 (2002) 205-215.
-
(2002)
J. Neuroimmunol.
, vol.129
, pp. 205-215
-
-
Feng, X.1
Petraglia, A.L.2
Chen, M.3
Byskosh, P.V.4
Boos, M.D.5
Reder, A.T.6
-
139
-
-
0034573578
-
Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden
-
K. Vandenbroeck, C. Hardt, J. Louage, P. Fiten, S. Jackel, I. Ronsse, J.T. Epplen, L.M. Grimaldi, T. Olsson, M.G. Marrosu, A. Billiau, G. Opdenakker, Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden, Genes Immun. 1 (2000) 290-292.
-
(2000)
Genes Immun.
, vol.1
, pp. 290-292
-
-
Vandenbroeck, K.1
Hardt, C.2
Louage, J.3
Fiten, P.4
Jackel, S.5
Ronsse, I.6
Epplen, J.T.7
Grimaldi, L.M.8
Olsson, T.9
Marrosu, M.G.10
Billiau, A.11
Opdenakker, G.12
-
140
-
-
0038689234
-
Protection from autoimmune brain inflammation in mice lacking IFN-regulatory factor-1 is associated with Th2-type cytokines
-
T. Buch, C. Uthoff-Hachenberg, A. Waisman, Protection from autoimmune brain inflammation in mice lacking IFN-regulatory factor-1 is associated with Th2-type cytokines, Int. Immunol. 15 (2003) 855-859.
-
(2003)
Int. Immunol.
, vol.15
, pp. 855-859
-
-
Buch, T.1
Uthoff-Hachenberg, C.2
Waisman, A.3
-
141
-
-
0025822355
-
Fos RNA accumulation in multiple sclerosis white matter tissue
-
J.S. Yu, T. Hayashi, E. Seboun, R.M. Sklar, T.H. Doolittle, S.L. Hauser, Fos RNA accumulation in multiple sclerosis white matter tissue, J. Neurol. Sci. 103 (1991) 209-215.
-
(1991)
J. Neurol. Sci.
, vol.103
, pp. 209-215
-
-
Yu, J.S.1
Hayashi, T.2
Seboun, E.3
Sklar, R.M.4
Doolittle, T.H.5
Hauser, S.L.6
-
142
-
-
0037289746
-
NFκB and AP-1 DNA binding activity in patients with multiple sclerosis
-
N. Flores, C. Duran, M.R. Blasco, C. Puerta, B. Dorado, A. Garcia-Merino, S. Ballester, NFκB and AP-1 DNA binding activity in patients with multiple sclerosis, J. Neuroimmunol. 135 (2003) 141-147.
-
(2003)
J. Neuroimmunol.
, vol.135
, pp. 141-147
-
-
Flores, N.1
Duran, C.2
Blasco, M.R.3
Puerta, C.4
Dorado, B.5
Garcia-Merino, A.6
Ballester, S.7
-
143
-
-
0033969317
-
Increased expression of c-rel, from the NF-κB/Rel family, in T cells from patients with systemic lupus erythematosus
-
P. Burgos, C. Metz, P. Bull, R. Pincheira, L. Massardo, C. Errazuriz, M.R. Bono, S. Jacobelli, A. Gonzalez, Increased expression of c-rel, from the NF-κB/Rel family, in T cells from patients with systemic lupus erythematosus, J. Rheumatol. 27 (2000) 116-127.
-
(2000)
J. Rheumatol.
, vol.27
, pp. 116-127
-
-
Burgos, P.1
Metz, C.2
Bull, P.3
Pincheira, R.4
Massardo, L.5
Errazuriz, C.6
Bono, M.R.7
Jacobelli, S.8
Gonzalez, A.9
-
144
-
-
0033179001
-
Abnormal NF-κB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression
-
H.K. Wong, G.M. Kammer, G. Dennis, G.C. Tsokos, Abnormal NFκB activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression, J. Immunol. 163 (1999) 1682-1689.
-
(1999)
J. Immunol.
, vol.163
, pp. 1682-1689
-
-
Wong, H.K.1
Kammer, G.M.2
Dennis, G.3
Tsokos, G.C.4
-
145
-
-
0034741071
-
Inhibition of NF-κB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice
-
S. Vallabhapurapu, R.P. Ryseck, M. Malewicz, D.S. Weih, F. Weih, Inhibition of NF-κB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice, Eur. J. Immunol. 31 (2001) 2612-2622.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2612-2622
-
-
Vallabhapurapu, S.1
Ryseck, R.P.2
Malewicz, M.3
Weih, D.S.4
Weih, F.5
-
146
-
-
0037288922
-
Monocyte response to Th1 stimulation and effector function toward human mesangial cells are not impaired in patients with lupus nephritis
-
T. Kuroiwa, R. Schlimgen, G.G. Illei, D.T. Boumpas, Monocyte response to
-
(2003)
Clin. Immunol.
, vol.106
, pp. 65-72
-
-
Kuroiwa, T.1
Schlimgen, R.2
Illei, G.G.3
Boumpas, D.T.4
-
147
-
-
0036290602
-
Expression of interleukin-12 and its signaling molecules in peripheral blood mononuclear cells in systemic lupus erythematosus patients
-
Z. Li, Y. Li, L. Huang, H. Xu, X. Yu, R. Ye, Expression of interleukin-12 and its signaling molecules in peripheral blood mononuclear cells in systemic lupus erythematosus patients, Chin. Med. J. 115 (2002) 846-850.
-
(2002)
Chin. Med. J.
, vol.115
, pp. 846-850
-
-
Li, Z.1
Li, Y.2
Huang, L.3
Xu, H.4
Yu, X.5
Ye, R.6
-
148
-
-
0041344320
-
Pivotal role of stat4 and stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice
-
C.O. Jacob, S. Zang, L. Li, V. Ciobanu, F. Quismorio, A. Mizutani, M. Satoh, M. Koss, Pivotal role of stat4 and stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice, J. Immunol. 171 (2003) 1564-1571.
-
(2003)
J. Immunol.
, vol.171
, pp. 1564-1571
-
-
Jacob, C.O.1
Zang, S.2
Li, L.3
Ciobanu, V.4
Quismorio, F.5
Mizutani, A.6
Satoh, M.7
Koss, M.8
-
149
-
-
0037406914
-
Differential contribution of IL-4 and STAT6 vs. STAT4 to the development of lupus nephritis
-
R.R. Singh, V. Saxena, S. Zang, L. Li, F.D. Finkelman, D.P. Witte, C.O. Jacob, Differential contribution of IL-4 and STAT6 vs. STAT4 to the development of lupus nephritis, J. Immunol. 170 (2003) 4818-4825.
-
(2003)
J. Immunol.
, vol.170
, pp. 4818-4825
-
-
Singh, R.R.1
Saxena, V.2
Zang, S.3
Li, L.4
Finkelman, F.D.5
Witte, D.P.6
Jacob, C.O.7
-
150
-
-
0029794221
-
Abnormality of Oct-1 DNA binding in T cells from Sjogren's syndrome patients
-
E. Flescher, N. Vela-Roch, N. Ogawa, T. Nakabayashi, A. Escalante, J.M. Anaya, H. Dang, N. Talal, Abnormality of Oct-1 DNA binding in T cells from Sjogren's syndrome patients, Eur. J. Immunol. 26 (1996) 2006-2011.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2006-2011
-
-
Flescher, E.1
Vela-Roch, N.2
Ogawa, N.3
Nakabayashi, T.4
Escalante, A.5
Anaya, J.M.6
Dang, H.7
Talal, N.8
-
151
-
-
0021714890
-
Autoimmunity and increased c-myb transcription
-
J.D. Mountz, A.D. Steinberg, D.M. Klinman, H.R. Smith, J.F. Mushinski, Autoimmunity and increased c-myb transcription, Science 226 (1984) 1087-1089.
-
(1984)
Science
, vol.226
, pp. 1087-1089
-
-
Mountz, J.D.1
Steinberg, A.D.2
Klinman, D.M.3
Smith, H.R.4
Mushinski, J.F.5
-
152
-
-
0034814052
-
Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus
-
S.J. Rozzo, J.D. Allard, D. Choubey, T.J. Vyse, S. Izui, G. Peltz, B.L. Kotzin, Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus, Immunity 15 (2001) 435-443.
-
(2001)
Immunity
, vol.15
, pp. 435-443
-
-
Rozzo, S.J.1
Allard, J.D.2
Choubey, D.3
Vyse, T.J.4
Izui, S.5
Peltz, G.6
Kotzin, B.L.7
-
153
-
-
0034684616
-
Expression and function of Ets transcription factors in mammalian development: A regulatory network
-
I.G. Maroulakou, D.B. Bowe, Expression and function of Ets transcription factors in mammalian development: a regulatory network, Oncogene 19 (2000) 6432-6442.
-
(2000)
Oncogene
, vol.19
, pp. 6432-6442
-
-
Maroulakou, I.G.1
Bowe, D.B.2
-
154
-
-
0033937768
-
3′ polymorphisms of ETS1 are associated with different clinical phenotypes in SLE
-
K.E. Sullivan, L.M. Piliero, T. Dharia, D. Goldman, M.A. Petri, 3′ polymorphisms of ETS1 are associated with different clinical phenotypes in SLE, Hum. Mutat. 16 (2000) 49-53.
-
(2000)
Hum. Mutat.
, vol.16
, pp. 49-53
-
-
Sullivan, K.E.1
Piliero, L.M.2
Dharia, T.3
Goldman, D.4
Petri, M.A.5
-
155
-
-
0037111374
-
Defective production of functional 98-κDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosus
-
Y.T. Juang, K. Tenbrock, M.P. Nambiar, M.F. Gourley, G.C. Tsokos, Defective production of functional 98-κDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosus, J. Immunol. 169 (2002) 6048-6055.
-
(2002)
J. Immunol.
, vol.169
, pp. 6048-6055
-
-
Juang, Y.T.1
Tenbrock, K.2
Nambiar, M.P.3
Gourley, M.F.4
Tsokos, G.C.5
-
156
-
-
0028876127
-
An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes
-
L. Zhang, A. Eddy, Y.T. Teng, M. Fritzler, M. Kluppel, F. Melet, A. Bernstein, An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes, Mol. Cell. Biol. 15 (1995) 6961-6970.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6961-6970
-
-
Zhang, L.1
Eddy, A.2
Teng, Y.T.3
Fritzler, M.4
Kluppel, M.5
Melet, F.6
Bernstein, A.7
-
157
-
-
0141566876
-
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background
-
K. Yoh, K. Shibuya, N. Morito, T. Nakano, K. Ishizaki, H. Shimohata, M. Nose, S. Izui, A. Shibuya, A. Koyama, J.D. Engel, M. Yamamoto, S. Takahashi, Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background, J. Am. Soc. Nephrol. 14 (2003) 2494-2502.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2494-2502
-
-
Yoh, K.1
Shibuya, K.2
Morito, N.3
Nakano, T.4
Ishizaki, K.5
Shimohata, H.6
Nose, M.7
Izui, S.8
Shibuya, A.9
Koyama, A.10
Engel, J.D.11
Yamamoto, M.12
Takahashi, S.13
-
158
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
T.A. Chatila, F. Blaeser, N. Ho, H.M. Lederman, C. Voulgaropoulos, C. Helms, A.M. Bowcock, JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome, J. Clin. Invest. 106 (2000) R75-R81.
-
(2000)
J. Clin. Invest.
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
Bowcock, A.M.7
-
159
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
S. Hori, T. Nomura, S. Sakaguchi, Control of regulatory T cell development by the transcription factor Foxp3, (Comment), Science 299 (2003) 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
160
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
J.D. Fontenot, M.A. Gavin, A.Y. Rudensky, Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nat. Immunol. 4 (2003) 330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
161
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
R. Khattri, T. Cox, S.A. Yasayko, F. Ramsdell, An essential role for Scurfin in CD4+CD25+ T regulatory cells, Nat. Immunol. 4 (2003) 337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
162
-
-
0037112047
-
Projection of an immunological self-shadow within the thymus by the aire protein
-
M.S. Anderson, E.S. Venanzi, L. Klein, Z. Chen, S.P. Berzins, S.J. Turley, H. von Boehmer, R. Bronson, A. Dierich, C. Benoist, D. Mathis, Projection of an immunological self-shadow within the thymus by the aire protein, Science 298 (2002) 1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
Von Boehmer, H.7
Bronson, R.8
Dierich, A.9
Benoist, C.10
Mathis, D.11
-
163
-
-
0032191170
-
Aiolos regulates B cell activation and maturation to effector state
-
J.H. Wang, N. Avitahl, A. Cariappa, C. Friedrich, T. Ikeda, A. Renold, K. Andrikopoulos, L. Liang, S. Pillai, B.A. Morgan, K. Georgopoulos, Aiolos regulates B cell activation and maturation to effector state, Immunity 9 (1998) 543-553.
-
(1998)
Immunity
, vol.9
, pp. 543-553
-
-
Wang, J.H.1
Avitahl, N.2
Cariappa, A.3
Friedrich, C.4
Ikeda, T.5
Renold, A.6
Andrikopoulos, K.7
Liang, L.8
Pillai, S.9
Morgan, B.A.10
Georgopoulos, K.11
-
164
-
-
0037442214
-
Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice
-
J. Sun, G. Matthias, M.J. Mihatsch, K. Georgopoulos, P. Matthias, Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice, J. Immunol. 170 (2003) 1699-1706.
-
(2003)
J. Immunol.
, vol.170
, pp. 1699-1706
-
-
Sun, J.1
Matthias, G.2
Mihatsch, M.J.3
Georgopoulos, K.4
Matthias, P.5
-
165
-
-
0035175548
-
Defective T cell activation and autoimmune disorder in Stra13-deficient mice
-
H. Sun, B. Lu, R.Q. Li, R.A. Flavell, R. Taneja, Defective T cell activation and autoimmune disorder in Stra13-deficient mice, Nat. Immunol. 2 (2001) 1040-1047.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1040-1047
-
-
Sun, H.1
Lu, B.2
Li, R.Q.3
Flavell, R.A.4
Taneja, R.5
-
166
-
-
0034816964
-
Delineating the genetic basis of systemic lupus erythematosus
-
E.K. Wakeland, K. Liu, R.R. Graham, T.W. Behrens, Delineating the genetic basis of systemic lupus erythematosus, Immunity 15 (2001) 397-408.
-
(2001)
Immunity
, vol.15
, pp. 397-408
-
-
Wakeland, E.K.1
Liu, K.2
Graham, R.R.3
Behrens, T.W.4
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