Monocyte response to Th1 stimulation and effector function toward human mesangial cells are not impaired in patients with lupus nephritis

Clinical Immunology

Volumn 106, Issue 1, 2003, Pages 65-72

  Kuroiwa, Takashi ^a,b,d   Schlimgen, Ryan ^a   Illei, Gabor G ^a   Boumpas, Dimitrios T ^a,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b GUNMA UNIVERSITY   (Japan)

^c UNIVERSITY OF CRETE   (Greece)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

Interferon ; Mesangial cells; Monocytes; Systemic lupus erythematosus; Th1

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P70; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; HUMAN; HUMAN CELL; KIDNEY CELL; KIDNEY INJURY; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE ACTIVATION; MALE; MESANGIUM CELL; MONOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UPREGULATION;

EID: 0037288922     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1521-6616(02)00022-0     Document Type: Article

References (27)

1. Alexopoulos E., Seron D., Hartley R.B., Cameron J.S. Lupus nephritis Correlation of interstitial cells with glomerular function . Kidney Int. 37:1990;100-109.
2. D'Agati V.D., Appel G.B., Estes D., Knowles D.M. 2nd, Pirani C.L. Monoclonal antibody identification of infiltrating mononuclear leukocytes in lupus nephritis. Kidney Int. 30:1986;573-581.
3. Noris M., Bernasconi S., Casiraghi F., Sozzani S., Gotti E., Remuzzi G., Mantovani A. Monocyte chemoattractant protein-1 is excreted in excessive amounts in the urine of patients with lupus nephritis. Lab. Invest. 73:1995;804-809.
4. Wada T., Yokoyama H., Su S.B., Mukaida N., Iwano M., Dohi K., Takahashi Y., Sasaki T., Furuichi K., Segawa C., Hisada Y., Ohta S., Takasawa K., Kobayashi K., Matsushima K. Monitoring urinary levels of monocyte chemotactic and activating factor reflects disease activity of lupus nephritis. Kidney Int. 49:1996;761-767.
5. Lloyd C.M., Minto A.W., Dorf M.E., Proudfoot A., Wells T.N., Salant D.J. RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J. Exp. Med. 185:1997;1371-1380.
6. Stout R.D. Macrophage activation by T cells Cognate and non-cognate signals . Curr. Opin. Immunol. 5:1993;398-403.
7. Stout R.D., Suttles J. The many roles of CD40 in cell-mediated inflammatory responses. Immunol. Today. 17:1996;487-492.
8. Grewal I.S., Flavell R.A. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16:1998;111-135.
9. Theofilopoulos A.N., Koundouris S., Kono D.H., Lawson B.R. The role of IFN-γ in systemic lupus erythematosus A challenge to the Th1/Th2 paradigm in autoimmunity . Arthritis Res. 3:2001;136-141.
10. Datta S.K., Kalled S.L. CD40-CD40 ligand interaction in autoimmune disease. Arthritis Rheum. 40:1997;1735-1745.
11. Kuroiwa T., Lee E.G., Danning C.L., Illei G.G., McInnes I.B., Boumpas D.T. CD40 ligand-activated human monocytes amplify glomerular inflammatory responses through soluble and cell-to-cell contact-dependent mechanisms. J. Immunol. 163:1999;2168-2175.
12. Horwitz D.A., Gray J.D., Behrendsen S.C., Kubin M., Rengaraju M., Ohtsuka K., Trinchieri G. Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum. 41:1998;838-844.
13. Liu T.F., Jones B.M. Impaired production of IL-12 in systemic lupus erythematosus. I. Excessive production of IL-10 suppresses production of IL-12 by monocytes. Cytokine. 10:1998;140-147.
14. Tan E.M., Cohen A.S., Fries J.F., Masi A.T., McShane D.J., Rothfield N.F., Schaller J.G., Talal N., Winchester R.J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1982;1271-1277.
15. Silver B.J., Jaffer F.E., Abboud H.E. Platelet-derived growth factor synthesis in mesangial cells Induction by multiple peptide mitogens . Proc. Natl. Acad. Sci. USA. 86:1989;1056-1060.
16. Denton M.D., Marsden D.A., Luscinskas F.W., Brenner B.M., Brady H.R. Cytokine-induced phagocyte adhesion to human mesangial cells role of CD11/CD18 integrins and ICAM-1 . Am. J. Physiol. 261:1991;F1071-1079.
17. Kuroiwa T., Lee E.G. Cellular interactions in the pathogenesis of lupus nephritis The role of T cells and macrophages in the amplification of the inflammatory process in the kidney . Lupus. 7:1998;597-603.
18. Gabay C., Cakir N., Moral F., Roux-Lombard P., Meyer O., Dayer J.M., Vischer T., Yazici H., Guerne P.A. Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity. J. Rheumatol. 24:1997;303-308.
19. Tokano Y., Morimoto S., Kaneko H., Amano H., Nozawa K., Takasaki Y., Hashimoto H. Levels of IL-12 in the sera of patients with systemic lupus erythematosus - relation to Th1- and Th2-derived cytokines. Clin. Exp. Immunol. 116:1999;169-173.
20. Hagiwara E., Gourley M.F., Lee S., Klinman D.K. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10 Interferon-γ-secreting cells in the peripheral blood . Arthritis Rheum. 39:1996;379-385.
21. Llorente L., Richaud-Patin Y., Fior R., Alcocer-Varela J., Wijdenes J., Flourrier B.M., Galanaud P., Emilie D. In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity. Arthritis Rheum. 37:1994;1647-1655.
22. Desai-Mehta A., Lu L., Ramsey-Goldman R., Datta S.K. Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J. Clin. Invest. 97:1996;2063-2073.
23. Koshy M., Berger D., Crow M.K. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J. Clin. Invest. 98:1996;826-837.
24. Blanco P., Palucka A.K., Gill M., Pascual V., Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science. 294:2001;1540-1543.
25. Katsiari C.G., Liossis S.N., Souliotis V.L., Dimopoulos A.M., Manoussakis M.N., Sfikakis P.P. Aberrant expression of the costimulatory molecule CD40 ligand on monocytes from patients with systemic lupus erythematosus. Clin. Immunol. 103:2002;54-62.
26. Hricik D.E., Chung-Park M., Sedor J.R. Glomerulonephritis. N. Engl. J. Med. 339:1998;888-899.
27. Esdaile J.M., Joseph L., MacKenzie T., Kashgarian M., Hayslett J.P. The benefit of early treatment with immunosuppressive agents in lupus nephritis. J. Rheumatol. 21:1994;2046-2051.