AP-1 and NF-κB regulation in rheumatoid arthritis and murine collagen-induced arthritis

Autoimmunity

Volumn 28, Issue 4, 1998, Pages 197-208

  Han, Zuoning ^a   Boyle, David L ^a   Manning, Anthony M ^b   Firestein, Gary S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CELGENE CORPORATION   (United States)

Author keywords

AP 1; Collagen induced arthritis; Mouse; NF B; Rheumatoid arthritis

Indexed keywords

COLLAGEN; COLLAGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; STROMELYSIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DNA BINDING; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; OSTEOARTHRITIS; RHEUMATOID ARTHRITIS;

EID: 0032428729     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939808995367     Document Type: Article

References (47)

1. Firestein, G.S. 1996. Etiology and pathogenesis of rheumatoid arthritis, In Textbook of Rheumatology, W.N. Kelley, ed. W.B. Saunders Company, Philadelphia, 5th edition, pp. 851-97.
2. Firestein, G.S. 1996. Invasive fibroblast-like synoviocytes in rheumatoid arthritis: Passive responders or transformed aggressors? Arthritis Rheum. 39: 1781-90.
3. Gay, S. and R.E. Gay. 1989. Cellular basis and oncogene expression of rheumatoid joint destruction. Rheumatol. Int. 9: 105-13.
4. Qu, Z., C.H. Garcia, L.M. O'Rourke, S.R. Planck, M. Kohl and J.T. Rosenbaum. 1994. Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining. Arthritis Rheum. 37: 212-20.
5. Firestein, G.S., J.M. Alvaro-Gracia and R. Maki. 1990. Quantitative analysis of cytokine gene expression in rheumatoid arthritis. J. Immunol. 144: 3347-53.
6. Arend, W.P. and J.M. Dayer. 1990. Cytokines and cytokine inhibitors or antaconists in rheumatoid arthritis. Arthritis Rheum. 33: 305-15.
7. Keyszer, G.M., A.H. Heer, J. Kriegsmann, T. Geiler, A. Trabandt, M. Keysser, R.E. Gay and S. Gay. 1995. Comparative analysis of cathepsin L, cathepsin D, and collagenase messenger RNA expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis, by in situ hybridization. Arthritis Rheum. 38: 976-84.
8. Firestein, G.S., M.M. Paine and B.H. Littman. 1991. Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium: Quantitative analysis and effect of intraarticular corticosteroids. Arthritis Rheum. 34: 1094-105.
9. McCachren, S.S., B.F. Haynes and J.E. Niedel. 1990. Localization of collagenase mRNA in rheumatoid arthritis synovium by in situ hybridization histochemistry. J. Clin. Immunol. 10: 19-27.
10. Karin, M., Zg Liu and E. Zandi. 1997. AP-1 function and regulation. Current Opin. Cell Biol. 9: 240-6.
11. Pierce, J.W., M. Lenardo and D. Baltimore. 1988. Oligonucleotide that binds nuclear factor NF-kappa B acts as a lymphoid-specific and inducible enhancer element. Proc. Nat. Acad. Sci. USA 85: 1482-6.
12. Wirth, T. and D. Baltimore. 1988. Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function. Embo J. 7: 3109-13.
13. Verma, I.M., J.K. Stevenson, E-M. Schwarz, D. Van Antwerp and S. Miyamoto. 1995. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev. 15, 9: 2723-35.
14. Baeuerle, P.A. and D. Baltimore. 1988. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 242: 540-6.
15. Miyamoto, S., P.J. Chiao and I.M. Verma. 1994. Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol. Cell Biol. 14: 3276-82.
16. Beauparlant, P. and J. Hiscott. 1996. Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis. Cyt. Growth Factor Rev. 7: 175-90.
17. Chen, C.C. and A.M. Manning. 1995. Transcriptional regulation of endothelial cell adhesion molecules: a dominant role for NF-kappa B. Agents Actions. Supplements 47: 135-41.
18. Alvaro-Gracia, J.M., N J. Zvaifler and G.S. Firestein. 1990. Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between IFN-gamma and TNF-alpha on HLA-DR expression, proliferation, collagenase production, and GM-CSF production by rheumatoid arthritis synoviocytes. J. Clin. Invest. 86: 1790-8.
19. Arnett, F.C., S.M. Edworthy, D.A. Bloch, D.J. McShane, J.F. Fries, N.S. Cooper, L.A. Healey, S.R. Kaplan, M.H. Liang, H.S. Luthra, et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31: 315-24.
20. Morales-Ducret, J., E. Wayner, M.J. Elices, J.M. AlvaroGracia, N.J. Zvaifler and G.S. Firestein. 1992. α4/β1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. J. Immunol. 149: 1424-31.
21. Schreiber, E., P. Mattias, M. Muller and W. Schaffner. 1989. Rapid detection of octamer binding proteins with mini-extracts prepared from a small number of cells. Nucl. Acids Res. 17: 6419.
22. Manning, A.M., F.P. Bell, C.L. Rosenbloom, J.G. Chosay, C.A. Simmons, J.L. Northrup, R.J. Shebuski, C.J. Dunn and D.C. Anderson. 1995. NF-κB is activated during acute inflammation in association with elevated endothelial adhesion molecule gene expression and leukocyte recruitment. J. Inflamm. 45: 283.
23. Sajjadi, F.G., K. Takabayashi, A. Foster, R. Domingo and G.S. Firestein. 1996. Inhibition of TNF-alpha gene expression by adenosine: The role of A3 adenosine receptors. J. Immunol. 156: 3435-42.
24. Westwick, J.K., C. Weitzel, A. Minden, M. Karin and D.A. Brenner. 1994. Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269: 26396-401.
25. Woessner Jr., J.F. 1991. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5: 2145-54.
26. Dayer, J.M., B. Beutler and A. Cerami. 1985. Cachectin/ tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J. Exp. Med. 162: 2163-8.
27. Barnes, P.J. and M. Karin. 1997. Nuclear factor-kappa B: a pivotal transcription factor in chronic inflammatory diseases. New Eng. J. Med. 336: 1066-71.
28. Stein, B., A.S. Baldwin Jr., D.W. Ballard, W.C. Greene, P. Angel and P. Herrlich. 1993. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. Embo J. 12: 3879-91.
29. Angel, P., M. Imagawa, R. Chiu, B. Stein, R.J. Imbra, H.J. Rahmsdorf, C. Jonat, P. Herrlich and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recoenized by a TPA-modulated trans-acting factor. Cell 49: 729-39.
30. Sen, R. and D. Baltimore. 1986. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46: 705-16.
31. Cross, S.L., N.F. Halden, M.J. Lenardo and W.J. Leonard. 1989. Functionally distinct NF-kappa B binding sites in the immunoglobulin kappa and IL-2 receptor alpha chain genes. Science 244: 466-9.
32. Baeuerle, P.A. and T. Henkel. 1994. Function and activation of NF-kappa B in the immune system. Ann. Rev. Immunol. 12: 141-79.
33. Zhong, H., H. SuYang, H. Erdjument-Bromage, P. Tempst and S. Ghosh. 1997. The transcriptional activity of NF-kappa B is regulated by the I kappa B-associated PKAc subunit throuch a cyclic AMP-independent mechanism. Cell 89: 413-24.
34. Bennett, B.L., R.G. Lacson, C.C. Chen, R. Cruz, J.S. Wheeler, R.F. Kletzien, A.G. Tomasselli, R.L. Heinrikson and A.M. Manning. 1996. Identification of signal-induced I kappa B-alpha kinases in human endothelial cells. J. Biol. Chem. 271: 19680-8.
35. Auphan, N., J.A. DiDonato, C. Rosette, A. Helmberg and M. Karin. 1995. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270: 286-90.
36. Deleuran, B.W., C.Q. Chu, M. Field, F.M. Brennan, T. Mitchell, M. Feldmann and R.N. Maini. 1992. Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha. Arthritis Rheum. 35: 1170-8.
37. Su, B. and M. Karin. 1996. Mitogen-activated protein kinase cascades and regulation of gene expression. Current Opin. Imnnmol. 8: 402-11.
38. Pierce, R.A., S. Sandefur, G.A.R. Doyle and H.G. Welgus. 1996. Monocytic cell type-specific transcriptional induction of collagenase. J. Clin. Invest. 97: 1890-9.
39. Handel, M.L., L.B. McMorrow and E.M. Gravallese. 1995. Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65. Arthritis Rheum. 38: 1762-70.
40. Marok, R., P.G. Winyard, A. Coumbe, M.L. Kus, K. Gaffney, S. Blades, P.I. Mapp, C.J. Morris, D.R. Blake, C. Kaltschmidt and P.A. Baeuerle. 1996. Activation of the transcription factor nuclear factor-kappa B in human inflamed synovial tissue. Arthritis Rheum. 39: 583-91.
41. Asahara, H., K. Fujisawa, T. Kobata, T. Hasunuma, T. Maeda, M. Asanuma, N. Ogawa, H. Inoue, T. Sumida and K. Nishioka. 1997. Direct evidence of high DNA binding activity of transcription factor AP-I in rheumatoid arthritis synovium. Arthritis Rheum. 40: 912-8.
42. Fujisawa, K., H. Aono, T. Hasunuma, K. Yamamoto, S. Mita and K. Nishioka. 1996. Activation of transcription factor NF-kappa B in human synovial cells in response to tumor necrosis factor alpha. Arthritis Rheum. 39: 197-203.
43. Asahara, H., M. Asanuma, N. Ogawa, S. Nishibayashi and H. Inoue. 1995. High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis. Biochem. Mol. Biol. Internat. 37: 827-32.
44. Tsao, P.W., T. Suzuki, R. Totsuka, T. Murata, T. Takagi, Y. Ohmachi, H. Fujimura and I. Takata. 1997. The effect of dexamethasone on the expression of activated NF-kappa B in adjuvant arthritis. Clin. Immunol. Immunopathol. 83: 173-8.
45. Rutter, J., U. Benbow, C.I. Coon and C.E. Brinckerhoff. 1997. Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1 beta in human fibroblasts and BC-8701 breast cancer cells. J. Cell. Biochem. 66: 322-36.
46. Tardif, G., J.P. Pelletier, M. Dupuis, J.E. Hambor and J. Martel-Pelletier. 1997. Cloning, sequencing and characterization of the 5′-flanking region of the human collagenase-3 gene. Biochem. J. 323: 13-6.
47. Pendas, A.M., M. Balbin, E. Llano, M.G. Jimenez and C. Lopez-Otin. 1997. Structural analysis and promoter characterization of the human collagenase-3 gene (MMP13). Genomics 40: 222-33.