Delineating the genetic basis of systemic lupus erythematosus

Immunity

Volumn 15, Issue 3, 2001, Pages 397-408

  Wakeland, Edward K ^a   Liu, Kui ^a   Graham, Robert R ^b   Behrens, Timothy W ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; FC RECEPTOR; HLA ANTIGEN;

AUTOIMMUNITY; CLINICAL TRIAL; DISEASE COURSE; DISEASE MODEL; DISEASE SEVERITY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC EPISTASIS; GENETIC LINKAGE; GENETIC PREDISPOSITION; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0034816964     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(01)00201-1     Document Type: Review

References (85)

1. Functional identification of the mouse circadian clock gene by transgenic BAC rescue
2. Antibody production in mice deficient for complement receptors 1 and 2 can be induced by IgG/Ag and IgE/Ag complexes
3. Genetics of systemic lupus erythematosus
4. Clustering of non-MHC susceptibility candidate loci in human autoimmune diseases
5. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
6. Studies of twins with systemic lupus erythematosus: A review of the literature and presentation of 12 additional sets
7. Spontaneous autoimmune disease in FcγRIIB-deficient mice results from strain-specific epistasis
8. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
9. Hereditary C1q deficiency and systemic lupus erythematosus
10. Characterization of single-nucleotide polymorphisms in coding regions of human genes
11. The human transcriptome map: Clustering of highly expressed genes in chromosomal domains
12. The lupus paradox
13. The role of complement and complement receptors in induction and regulation of immunity
14. The role of complement in B cell activation and tolerance
15. Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2
16. Genetic remodeling of protein glycosylation in vivo induces autoimmune disease
17. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
18. Genomics of the major histocompatibility complex: Haplotypes, duplication, retroviruses and disease
19. A revised estimate of twin concordance in systemic lupus erythematosus
20. Genetic analysis of the NZB contribution to lupus-like autoimmune disease
21. Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner
22. An MRL/MpJ-Ipr/Ipr substrain with a limited expansion of Ipr double-negative T cells and a reduced autoimmune syndrome
23. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
24. Recent advances in the genetics of systemic lupus erythematosus
25. Genome screening in human systemic lupus erythematosus: Results from a second Minnesota cohort and combined analyses of 187 sib-pair families
26. Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus
27. Genome scan of human systemic lupus erythematosus by regression modeling: Evidence of linkage and epistasis at 4p16-15.2
28. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
29. The genetics of human systemic lupus erythematosus
30. Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice
31. The epidemiology of systemic lupus erythematosus
32. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
33. Familial aggregation of systemic lupus erythematosus
34. Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice
35. Relationship between C4 null genes, HLA-D region antigens, and genetic susceptibility to systemic lupus erythematosus in Caucasian and black Americans
36. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
37. Age- and sex-related glomerulonephritis in New Zealand white mice
38. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
39. Lupus susceptibility loci in New Zealand mice
40. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
41. A family survey of lupus erythematosus. 1. Heritability
42. A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q
43. Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: Identification of a candidate segment of ancestral DNA by haplotype mapping
44. The origin of anti-nuclear antibodies in bcl-2 transgenic mice
45. Genetic dissection of SLE pathogenesis: Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
46. Genetic dissection of SLE pathogenesis: Sle2 on murine chromosome 4 leads to B-cell hyperactivity
47. Genetic dissection of lupus pathogenesis: A recipe for nephrophilic autoantibodies
48. Genetic dissection of SLE pathogenicity: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death
49. Polygenic control of susceptibility to murine systemic lupus erythematosus
50. Functional dissection of systemic lupus erythematosus using congenic mouse strains
51. Multiplex inheritance of component phenotypes in a murine model of lupus
52. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis
53. Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains
54. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
55. Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in african-american pedigrees
56. Features of systemic lupus erythematosus in Dnase1-deficient mice
57. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
58. A frameshift mutation in NOD2 associated with susceptibiity to Crohn's disease
59. Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene
60. Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis
61. Enhanced susceptibility to lupus contributed from the nonautoimmune C57BL/10, but not C57BL/6, genome
62. Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans
63. Role of cyclin kinase inhibitor p21 in systemic autoimmunity
64. Genetics of systemic lupus erythematosus
65. The effect of ethnicity on major histocompatibility complex complement allotypes and extended haplotypes in patients with systemic lupus erythematosus
66. Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families
67. Methods for the study of histocompatibility genes
68. The 1982 revised criteria for the classification of systemic lupus erythematosus
69. The basis of autoimmunity: Part I mechanisms of aberrant self-recognition
70. The basis of autoimmunity: Part II genetic predisposition
71. PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus
72. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus
73. The sequence of the human genome
74. Loci predisposing to autoimmunity in MRL-Fas Ipr and C57BL/6-FasIpr mice
75. Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice
76. Backcross analysis of genes linked to autoantibody production in New Zealand white mice
77. Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice
78. Speed congenics: A classic technique moves into the fast lane (relatively speaking)
79. Lupus, DNase and defective disposal of cellular debris
80. The genetics of complex autoimmune diseases: Non-MHC susceptibility genes
81. The influence of the Ipr gene on B cell activation: Differential antibody expression in Ipr congenic mouse strains
82. A novel polymorphism of FcγRIIIa (CD16) alters receptor function and predisposes to autoimmune disease
83. Lack of gene deletion for complement C4A deficiency in Japanese patients with systemic lupus erythematosus
84. Mutation of DNASE1 in people with systemic lupus erythematosus