-
1
-
-
0032499260
-
Chemokines and leukocyte traffic
-
Baggiolini M. Chemokines and leukocyte traffic. Nature 1998, 392, 565-568.
-
(1998)
Nature
, vol.392
, pp. 565-568
-
-
Baggiolini, M.1
-
2
-
-
0031809008
-
Chemokines and HIV-1 second receptors: The therapeutic connection
-
Cairns JS, D'Souza MP. Chemokines and HIV-1 second receptors: the therapeutic connection. Nature Medicine 1998, 4, 563-568.
-
(1998)
Nature Medicine
, vol.4
, pp. 563-568
-
-
Cairns, J.S.1
D'Souza, M.P.2
-
3
-
-
0032562614
-
Identification of a potent selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration
-
White JR, Lee JM, Young PR, et al. Identification of a potent selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration. J Biol Chem 1998, 273, 10095-10098.
-
(1998)
J Biol Chem
, vol.273
, pp. 10095-10098
-
-
White, J.R.1
Lee, J.M.2
Young, P.R.3
-
4
-
-
14444283367
-
Identification and Characterization of Small Molecule Functional Antagonists of the CCR1 Chemokine Receptor
-
Hesselgesser J, Ng HP, May K, et al. Identification and Characterization of Small Molecule Functional Antagonists of the CCR1 Chemokine Receptor. J Biol Chem 1998, 273, 15687-15692.
-
(1998)
J Biol Chem
, vol.273
, pp. 15687-15692
-
-
Hesselgesser, J.1
Ng, H.P.2
May, K.3
-
5
-
-
0028803845
-
An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
-
Karpus WJ, Lukacs NW, McRae BL, Stricter RM, Kunkel SL, Miller SD. An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol 1995, 155, 5003-5010.
-
(1995)
J Immunol
, vol.155
, pp. 5003-5010
-
-
Karpus, W.J.1
Lukacs, N.W.2
McRae, B.L.3
Stricter, R.M.4
Kunkel, S.L.5
Miller, S.D.6
-
6
-
-
0028047276
-
-
Snowden N, Hajeer A, Thomson W, Ollier B. Lancet 1994, 343, 547-548.
-
(1994)
Lancet
, vol.343
, pp. 547-548
-
-
Snowden, N.1
Hajeer, A.2
Thomson, W.3
Ollier, B.4
-
7
-
-
0026904262
-
Protein hormones and their receptors
-
Young PR. Protein hormones and their receptors. Curr Opin Biotechnology 1992, 3, 408-421.
-
(1992)
Curr Opin Biotechnology
, vol.3
, pp. 408-421
-
-
Young, P.R.1
-
8
-
-
0028887623
-
Cytokines and their receptor complexes
-
Davies DR, Wlodawer A. Cytokines and their receptor complexes. FASEB J 1995, 9, 50-56.
-
(1995)
FASEB J
, vol.9
, pp. 50-56
-
-
Davies, D.R.1
Wlodawer, A.2
-
10
-
-
0029775672
-
-
Samanen JM, Ali FE, Barton LS, et al. J Med Chem 1996, 39, 4867-4870.
-
(1996)
J Med Chem
, vol.39
, pp. 4867-4870
-
-
Samanen, J.M.1
Ali, F.E.2
Barton, L.S.3
-
11
-
-
0031841054
-
Design and synthesis of small molecule interlueikin-1 receptor antagonists based on a benzene template
-
Sarabu R, Cooper JP, Cook CM, Gillespie P, Perrotta AV, Olson GL. Design and synthesis of small molecule interlueikin-1 receptor antagonists based on a benzene template. Drug design & Discov 1998, 15, 191-198.
-
(1998)
Drug Design & Discov
, vol.15
, pp. 191-198
-
-
Sarabu, R.1
Cooper, J.P.2
Cook, C.M.3
Gillespie, P.4
Perrotta, A.V.5
Olson, G.L.6
-
12
-
-
10544225751
-
AF12198, a novel low molecular weight antagonist, selectively binds to the human type I interleukin (IL)-1 receptor and blocks in vivo responses to IL-1
-
Akeson AL, Woods CW, Hsieh LC, et al. AF12198, a novel low molecular weight antagonist, selectively binds to the human type I interleukin (IL)-1 receptor and blocks in vivo responses to IL-1. J Biol Chem 1996, 271, 30517-30523.
-
(1996)
J Biol Chem
, vol.271
, pp. 30517-30523
-
-
Akeson, A.L.1
Woods, C.W.2
Hsieh, L.C.3
-
13
-
-
0032086337
-
Targeting growth factor and cytokine receptors with recombinant peptide libraries
-
Dower WJ. Targeting growth factor and cytokine receptors with recombinant peptide libraries. Curr Opinion Chem Biol 1998, 2, 328-334.
-
(1998)
Curr Opinion Chem Biol
, vol.2
, pp. 328-334
-
-
Dower, W.J.1
-
14
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton NC, Farrrell FX, Chang R, et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science 1996, 273, 458-463.
-
(1996)
Science
, vol.273
, pp. 458-463
-
-
Wrighton, N.C.1
Farrrell, F.X.2
Chang, R.3
-
15
-
-
0029798402
-
Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8A
-
Livnah O, Stura EA, Johnson DL, et al. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8A. Science 1996, 273, 464-471.
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
Stura, E.A.2
Johnson, D.L.3
-
16
-
-
0030717635
-
Increased potency of an erythropoietin peptide mimetic through covalent dimerization
-
Wrighton NC, Balasubramanian P, Barbone FP, et al. Increased potency of an erythropoietin peptide mimetic through covalent dimerization. Nature Biotech 1997, 15, 1261-1265.
-
(1997)
Nature Biotech
, vol.15
, pp. 1261-1265
-
-
Wrighton, N.C.1
Balasubramanian, P.2
Barbone, F.P.3
-
17
-
-
0030773876
-
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine
-
Cwirla SE, Balasubramanian P, Duffin DJ, et al. Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine. Science 1997, 276, 1696-1699.
-
(1997)
Science
, vol.276
, pp. 1696-1699
-
-
Cwirla, S.E.1
Balasubramanian, P.2
Duffin, D.J.3
-
18
-
-
0032504007
-
A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor
-
Tian S-S, Lamb P, King AG, et al. A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor. Science 1998, 281, 257-259.
-
(1998)
Science
, vol.281
, pp. 257-259
-
-
Tian, S.-S.1
Lamb, P.2
King, A.G.3
-
19
-
-
0028879656
-
Inhibitors of protein tyrosine kinases
-
Fry DW, Bridges AJ. Inhibitors of protein tyrosine kinases. Curr Opin Biotech 1995, 6, 662-667.
-
(1995)
Curr Opin Biotech
, vol.6
, pp. 662-667
-
-
Fry, D.W.1
Bridges, A.J.2
-
20
-
-
0029925701
-
Targeting signal transduction for disease therapy
-
Levitzki A. Targeting signal transduction for disease therapy. Curr Opin Cell Biology 1996, 8, 239-244.
-
(1996)
Curr Opin Cell Biology
, vol.8
, pp. 239-244
-
-
Levitzki, A.1
-
21
-
-
0028968949
-
Tyrosine kinase inhibition: An approach to drug development
-
Levitzki A, Gazit A. Tyrosine kinase inhibition: an approach to drug development. Science 1995, 267, 1782-1788.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
22
-
-
0030945871
-
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
-
Mohammadi M, McMahon G, Sun L, et al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 1997, 276, 955-960.
-
(1997)
Science
, vol.276
, pp. 955-960
-
-
Mohammadi, M.1
McMahon, G.2
Sun, L.3
-
23
-
-
0028142387
-
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
-
Fry DW, Krake AJ, McMichael A, et al. A specific inhibitor of the epidermal growth factor receptor tyrosine kinase. Science 1995, 265, 1093-1095.
-
(1995)
Science
, vol.265
, pp. 1093-1095
-
-
Fry, D.W.1
Krake, A.J.2
McMichael, A.3
-
24
-
-
0028968622
-
Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class
-
Buchdunger E, Zimmermann J, Mett H, et al. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci USA 1995, 92, 2558-2562.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2558-2562
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
-
25
-
-
0031914520
-
Phosphodiesterase isozymes: Molecular targets for novel antiasthma agents
-
Torphy TJ. Phosphodiesterase isozymes: molecular targets for novel antiasthma agents. American Journal of Respiratory & Critical Care Medicine 1998, 157, 351-370.
-
(1998)
American Journal of Respiratory & Critical Care Medicine
, vol.157
, pp. 351-370
-
-
Torphy, T.J.1
-
26
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
Beavo JA. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 1995, 75, 725-748.
-
(1995)
Physiol Rev
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
27
-
-
0027315234
-
The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-a production by human mononuclear cells
-
Semmler J, Wachtel H, Endres S. The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-a production by human mononuclear cells. Int J Immunopharmacol 1993, 15, 409-410.
-
(1993)
Int J Immunopharmacol
, vol.15
, pp. 409-410
-
-
Semmler, J.1
Wachtel, H.2
Endres, S.3
-
28
-
-
0027292201
-
Modulation of TNF alpha and IL-1 beta from endotoxin-stimulated monocytes by selective PDE isozyme inhibitors
-
Molnar KK, Yonno L, Heaslip R, Weichman B. Modulation of TNF alpha and IL-1 beta from endotoxin-stimulated monocytes by selective PDE isozyme inhibitors. Agents & Actions 1993, 39, C77-C79.
-
(1993)
Agents & Actions
, vol.39
-
-
Molnar, K.K.1
Yonno, L.2
Heaslip, R.3
Weichman, B.4
-
29
-
-
0028134973
-
Characterization of cAMP-dependent inhibition of LPS-induced TNF alpha production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor
-
Prabhakar U, Lipshutz D, Bartus JO, et al. Characterization of cAMP-dependent inhibition of LPS-induced TNF alpha production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor. International Journal of Immunopharmacology 1994, 16, 805-816.
-
(1994)
International Journal of Immunopharmacology
, vol.16
, pp. 805-816
-
-
Prabhakar, U.1
Lipshutz, D.2
Bartus, J.O.3
-
30
-
-
0028904551
-
Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors
-
Verghese MW, McConnell RT, Strickland AB, et al. Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors. Journal of Pharmacology & Experimental Therapeutics 1995, 272, 1313-1320.
-
(1995)
Journal of Pharmacology & Experimental Therapeutics
, vol.272
, pp. 1313-1320
-
-
Verghese, M.W.1
McConnell, R.T.2
Strickland, A.B.3
-
31
-
-
0030984905
-
The effect of a novel orally-active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic patients
-
Harbinson PL, MacLeod D, Hawksworth R, et al. The effect of a novel orally-active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic patients. Eur Resp J 1997, 10, 1008-1014.
-
(1997)
Eur Resp J
, vol.10
, pp. 1008-1014
-
-
Harbinson, P.L.1
MacLeod, D.2
Hawksworth, R.3
-
32
-
-
0031467021
-
The use of cytokine inhibitors. A new therapeutic insight into heart failure
-
Matsumori A. The use of cytokine inhibitors. A new therapeutic insight into heart failure. International Journal of Cardiology 1997, 62, S3-S12.
-
(1997)
International Journal of Cardiology
, vol.62
-
-
Matsumori, A.1
-
34
-
-
0031919849
-
JAKS and STATS: Biological implications
-
Leonard WJ, O'Shea JJ. JAKS and STATS: Biological implications. Annu Rev Immunol 1998, 16, 293-322.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
35
-
-
0030765924
-
Jaks, STATs, Cytokine Singal Transduction, and Immunoregulation: Are we there yet?
-
O'Shea JJ. Jaks, STATs, Cytokine Singal Transduction, and Immunoregulation: Are we there yet? Immunity 1997, 7, 1-11.
-
(1997)
Immunity
, vol.7
, pp. 1-11
-
-
O'Shea, J.J.1
-
36
-
-
0029739627
-
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
-
Xu X, Sun YL, Hoey T. Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain. Science 1996, 273, 794-797.
-
(1996)
Science
, vol.273
, pp. 794-797
-
-
Xu, X.1
Sun, Y.L.2
Hoey, T.3
-
37
-
-
0029767462
-
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
-
Bhattacharya S, Eckner R, Grossman S, et al. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature 1996, 383, 344-347.
-
(1996)
Nature
, vol.383
, pp. 344-347
-
-
Bhattacharya, S.1
Eckner, R.2
Grossman, S.3
-
38
-
-
0030449174
-
Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
-
Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Darnell JEJ. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc Natl Acad Sci USA 1996, 93, 15092-15096.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15092-15096
-
-
Zhang, J.J.1
Vinkemeier, U.2
Gu, W.3
Chakravarti, D.4
Horvath, C.M.5
Darnell, J.E.J.6
-
39
-
-
0031037363
-
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
-
Horvai AE, Xu L, Korzus E, et al. Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci USA 1996, 94, 1074-1079.
-
(1996)
Proc Natl Acad Sci USA
, vol.94
, pp. 1074-1079
-
-
Horvai, A.E.1
Xu, L.2
Korzus, E.3
-
40
-
-
0029557904
-
Stat1 depends on transcriptional synergy with Sp1
-
Look DC, Pelletier MR, Tidwell RM, Roswit WT, Holtzman MJ. Stat1 depends on transcriptional synergy with Sp1. J Biol Chem 1995, 270, 264-267.
-
(1995)
J Biol Chem
, vol.270
, pp. 264-267
-
-
Look, D.C.1
Pelletier, M.R.2
Tidwell, R.M.3
Roswit, W.T.4
Holtzman, M.J.5
-
41
-
-
0029075875
-
Cooperative transcriptional activity of Jun and Stat3 beta, a shhort form of Stat3
-
Schaefer TS, Sanders LK, Nathans D. Cooperative transcriptional activity of Jun and Stat3 beta, a shhort form of Stat3. Proc Natl Acad Sci USA 1995, 92, 9097-9101.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9097-9101
-
-
Schaefer, T.S.1
Sanders, L.K.2
Nathans, D.3
-
42
-
-
0029851231
-
Functional interactions between Stat5 and the glucocorticoid receptor
-
Stocklin E, Wissler M, Gouilleux F, Groner B. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 1996, 383, 726-728.
-
(1996)
Nature
, vol.383
, pp. 726-728
-
-
Stocklin, E.1
Wissler, M.2
Gouilleux, F.3
Groner, B.4
-
43
-
-
0028942656
-
Requirement for serine phosphorylation for formation of STAT-promoter complexes
-
Zhang X, Blenis J, Li HC, Schindler C, Chen-Kiang S. Requirement for serine phosphorylation for formation of STAT-promoter complexes. Science 1995, 267, 1990-1994.
-
(1995)
Science
, vol.267
, pp. 1990-1994
-
-
Zhang, X.1
Blenis, J.2
Li, H.C.3
Schindler, C.4
Chen-Kiang, S.5
-
44
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z, Zhong Z, Darnel JEJ. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995, 82, 241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnel, J.E.J.3
-
45
-
-
0031800490
-
The SOCS proteins: A new family of negative regulators of signal transduction
-
Nicholson SE, Hilton DJ. The SOCS proteins: a new family of negative regulators of signal transduction. Journal of Leukocyte Biology 1998, 63, 665-668.
-
(1998)
Journal of Leukocyte Biology
, vol.63
, pp. 665-668
-
-
Nicholson, S.E.1
Hilton, D.J.2
-
46
-
-
13344295097
-
Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor
-
Meydan N, Grunberger T, Dadi H, et al. Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor. Nature 1996, 379, 645-648.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
-
47
-
-
0031982630
-
Activation of the Jak2-Stat5 signaling pathway in Nb2 lymphoma cells by an anti-apoptotic agent, aurintricarboxylic acid
-
Rui H, Xu J, Mehta S, et al. Activation of the Jak2-Stat5 signaling pathway in Nb2 lymphoma cells by an anti-apoptotic agent, aurintricarboxylic acid. J Biol Chem 1998, 273, 28-32.
-
(1998)
J Biol Chem
, vol.273
, pp. 28-32
-
-
Rui, H.1
Xu, J.2
Mehta, S.3
-
48
-
-
0029896163
-
Regulation, structures and functions of src
-
Brown MT, Cooper JA. Regulation, structures and functions of src. Biochem Biophys Acta 1996, 1287, 121-149.
-
(1996)
Biochem Biophys Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
49
-
-
0031439247
-
Cellular functions regulated by src family kinases
-
Thomas SM, Brugge JS. Cellular functions regulated by src family kinases. Annu Rev Cell Dev Biol 1997, 13, 513-609.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
50
-
-
0028859279
-
Protein modules and signalling networks
-
Pawson T. Protein modules and signalling networks. Nature 1995, 373, 573-580.
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
51
-
-
0031457622
-
Signaling through scaffold, anchoring, and adaptor proteins
-
Pawson T, Scott JD. Signaling through scaffold, anchoring, and adaptor proteins. Science 1997, 278, 2075-2080.
-
(1997)
Science
, vol.278
, pp. 2075-2080
-
-
Pawson, T.1
Scott, J.D.2
-
52
-
-
0028047349
-
Phosphotyrosine phosphatases with SH2 domains: Regulators of signal transduction
-
Feng GS, Pawson T. Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction. Trends Genet 1994, 10, 54-58.
-
(1994)
Trends Genet
, vol.10
, pp. 54-58
-
-
Feng, G.S.1
Pawson, T.2
-
53
-
-
0030891168
-
Leukocyte protein tyrosine kinases: Potential targets for drug discovery
-
Bolen JB, Brugge JS. Leukocyte protein tyrosine kinases: potential targets for drug discovery. Annual Review of Immunology 1997, 15, 371-404.
-
(1997)
Annual Review of Immunology
, vol.15
, pp. 371-404
-
-
Bolen, J.B.1
Brugge, J.S.2
-
54
-
-
0030066325
-
Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2
-
Eck MJ, Pluskey S, Trub T, Harrison SC, Shoelson SE. Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2. Nature 1996, 379, 277-280.
-
(1996)
Nature
, vol.379
, pp. 277-280
-
-
Eck, M.J.1
Pluskey, S.2
Trub, T.3
Harrison, S.C.4
Shoelson, S.E.5
-
55
-
-
84988043558
-
Molecular basis for the interaction of the protein tyrosine kinase ZAP-70 with the T cell receptor
-
Hatada MH, Lu XL, Laird ER, et al. Molecular basis for the interaction of the protein tyrosine kinase ZAP-70 with the T cell receptor. Nature 1995, 377, 32-38.
-
(1995)
Nature
, vol.377
, pp. 32-38
-
-
Hatada, M.H.1
Lu, X.L.2
Laird, E.R.3
-
56
-
-
0030029143
-
-
Hanke JH, Gardner JP, Dow RL, et al. J Biol Chem 1996, 271, 695-701.
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
-
57
-
-
0030663666
-
Inositol lipid 5-phosphatases - Traffic signals and signal traffic
-
Woscholski R, Parker PJ. Inositol lipid 5-phosphatases - traffic signals and signal traffic. Trends Biochem Sci 1997, 22, 427-431.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 427-431
-
-
Woscholski, R.1
Parker, P.J.2
-
58
-
-
0030805703
-
Phosphoinositide 3 kinases: A conserved family of signal transducers
-
Vanhaesbroeck B, Leevers SJ, Panayotoy G, Waterfield MD. Phosphoinositide 3 kinases: a conserved family of signal transducers. Trends Biochem Sci 1997, 22, 276-272.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 276-1272
-
-
Vanhaesbroeck, B.1
Leevers, S.J.2
Panayotoy, G.3
Waterfield, M.D.4
-
59
-
-
0031903015
-
Downstream signalling events regulated by phosphatidylinositol 3-kinase activity
-
Duronio V, Scheid MP, Ettinger S. Downstream signalling events regulated by phosphatidylinositol 3-kinase activity. Cell Signal 1998, 10, 233-239.
-
(1998)
Cell Signal
, vol.10
, pp. 233-239
-
-
Duronio, V.1
Scheid, M.P.2
Ettinger, S.3
-
60
-
-
0029939448
-
PH domains: Diverse sequences with a common fold recruit signalling molecules to the cell surface
-
Lemmon M, Ferguson KM, Schlessinger J. PH domains: diverse sequences with a common fold recruit signalling molecules to the cell surface. Cell 1996, 85, 621-624.
-
(1996)
Cell
, vol.85
, pp. 621-624
-
-
Lemmon, M.1
Ferguson, K.M.2
Schlessinger, J.3
-
61
-
-
0027470177
-
-
Bellacosa A, Franke TF, Gonzalez-Portal ME, et al. Oncogene 1993, 8, 745-754.
-
(1993)
Oncogene
, vol.8
, pp. 745-754
-
-
Bellacosa, A.1
Franke, T.F.2
Gonzalez-Portal, M.E.3
-
62
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
Alessi DR, Cohen P. Mechanism of activation and function of protein kinase B. Curr Opin Genet Develop 1998, 8, 55-62.
-
(1998)
Curr Opin Genet Develop
, vol.8
, pp. 55-62
-
-
Alessi, D.R.1
Cohen, P.2
-
63
-
-
0031015986
-
A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its plekstrin homology domain
-
Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its plekstrin homology domain. Mol Cell Biol 1997, 17, 338-344.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 338-344
-
-
Klippel, A.1
Kavanaugh, W.M.2
Pot, D.3
Williams, L.T.4
-
64
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
-
Alessi DR, James SR, Downes CP, et al. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr Biol 1997, 7, 261-269.
-
(1997)
Curr Biol
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
-
65
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, et al. Role of translocation in the activation and function of protein kinase B. J Biol Chem 1997, 272, 31515-31324.
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-131324
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
-
66
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/akt cell survival pathway
-
Pap M, Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/akt cell survival pathway. J Biol Chem 1998, 273, 19929-19932.
-
(1998)
J Biol Chem
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
67
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997, 278, 687-689.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Del Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
68
-
-
0030890933
-
Transduction of interleukin-2 anti-apoptotic and proliferative signals via Akt protein kinase
-
Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Transduction of interleukin-2 anti-apoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad. Sci USA 1997, 94, 3627-3632.
-
(1997)
Proc Natl Acad. Sci USA
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
70
-
-
0028321727
-
Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes
-
Thelen M, Wymann MP, Langen H. Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Natl Acad Sci USA 1994, 91, 4960-4964.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4960-4964
-
-
Thelen, M.1
Wymann, M.P.2
Langen, H.3
-
71
-
-
0028170210
-
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. J Biol Chem 1994, 269, 5241-5248.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
72
-
-
0032581522
-
A functional PtdIns(3)P-binding motif
-
Patki V, Lawe DC, Corvera S, Virbasius JV, Chawla A. A functional PtdIns(3)P-binding motif. Nature 1998, 394, 433-434.
-
(1998)
Nature
, vol.394
, pp. 433-434
-
-
Patki, V.1
Lawe, D.C.2
Corvera, S.3
Virbasius, J.V.4
Chawla, A.5
-
73
-
-
0032581670
-
FYVE fingers bind PtdIns(3)P
-
Gaullier J-M, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R. FYVE fingers bind PtdIns(3)P. Nature 1998, 394.
-
(1998)
Nature
, vol.394
-
-
Gaullier, J.-M.1
Simonsen, A.2
D'Arrigo, A.3
Bremnes, B.4
Stenmark, H.5
Aasland, R.6
-
74
-
-
0030707884
-
Sirolimus, a new, potent immunosuppressive agent
-
Kelly PA, Gruber SA, Behbod F, Kahan BD. Sirolimus, a new, potent immunosuppressive agent. [Review] [74 refs]. Pharmacotherapy 1997, 17, 1148-1156.
-
(1997)
Pharmacotherapy
, vol.17
, pp. 1148-1156
-
-
Kelly, P.A.1
Gruber, S.A.2
Behbod, F.3
Kahan, B.D.4
-
75
-
-
0027382875
-
Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and vps34 abrogate rapamycin cytotoxicity
-
Cafferkey R, Young PR, McLaughlin M, et al. Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and vps34 abrogate rapamycin cytotoxicity. Mol Cell Biol 1993, 13, 6012-6023.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6012-6023
-
-
Cafferkey, R.1
Young, P.R.2
McLaughlin, M.3
-
76
-
-
0027311858
-
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
-
Kunz J, Henriquez R, Schneider U, Deuter-Reinhard M, Movva NR, Hall MN. Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell 1993, 73, 585-596.
-
(1993)
Cell
, vol.73
, pp. 585-596
-
-
Kunz, J.1
Henriquez, R.2
Schneider, U.3
Deuter-Reinhard, M.4
Movva, N.R.5
Hall, M.N.6
-
77
-
-
0028239893
-
RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 1994, 78, 35-43.
-
(1994)
Cell
, vol.78
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
78
-
-
0028561918
-
Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue
-
Stan R, McLaughlin MM, Cafferkey R, Johnson RK, Rosenberg M, Livi GP. Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. Journal of Biological Chemistry 1994, 269, 32027-32030.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 32027-32030
-
-
Stan, R.1
McLaughlin, M.M.2
Cafferkey, R.3
Johnson, R.K.4
Rosenberg, M.5
Livi, G.P.6
-
79
-
-
0030175487
-
Phosphatidylinositol 3-kinase related kinases
-
Abraham RT. Phosphatidylinositol 3-kinase related kinases. Current Opinion in Immunology 1996, 8, 412-418.
-
(1996)
Current Opinion in Immunology
, vol.8
, pp. 412-418
-
-
Abraham, R.T.1
-
80
-
-
0030881836
-
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
-
Brunn GJ, Hudson CC, Sekulic A, et al. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 1997, 277, 99-101.
-
(1997)
Science
, vol.277
, pp. 99-101
-
-
Brunn, G.J.1
Hudson, C.C.2
Sekulic, A.3
-
81
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC, Jr., Abraham RT. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO Journal 1996, 15, 5256-5267.
-
(1996)
EMBO Journal
, vol.15
, pp. 5256-5267
-
-
Brunn, G.J.1
Williams, J.2
Sabers, C.3
Wiederrecht, G.4
Lawrence J.C., Jr.5
Abraham, R.T.6
-
82
-
-
0030707562
-
TOR signalling and control of cell growth
-
Thomas G, Hall MN. TOR signalling and control of cell growth. Curr Opin Cell Biology 1997, 9, 782-787.
-
(1997)
Curr Opin Cell Biology
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
83
-
-
2642631745
-
Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation
-
Ruhlmann A, Nordheim A. Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation. Immunobiology 1997, 198, 192-206.
-
(1997)
Immunobiology
, vol.198
, pp. 192-206
-
-
Ruhlmann, A.1
Nordheim, A.2
-
84
-
-
0028852791
-
Three-dimensional structure and actions of immunosuppressants and their immunophilins
-
Braun W, Kallen J, Mikol V, Walkinshaw MD, Wuthrich K. Three-dimensional structure and actions of immunosuppressants and their immunophilins. FASEB Journal 1995, 9, 63-72.
-
(1995)
FASEB Journal
, vol.9
, pp. 63-72
-
-
Braun, W.1
Kallen, J.2
Mikol, V.3
Walkinshaw, M.D.4
Wuthrich, K.5
-
85
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu J, Farmer JD, Jr., Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66, 807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer J.D., Jr.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
86
-
-
0032577483
-
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin
-
Klee CB, Ren H, Wang X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. Journal of Biological Chemistry 1998, 273, 13367-13370.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 13367-13370
-
-
Klee, C.B.1
Ren, H.2
Wang, X.3
-
88
-
-
0026768730
-
The immunosuppressive and toxic effect of FK506 are mechanistically related: Pharmacology of a novel antagonist of FK506 and rapamycin
-
Dumont FJ, Staruch MJ, Koprak SL, et al. The immunosuppressive and toxic effect of FK506 are mechanistically related: pharmacology of a novel antagonist of FK506 and rapamycin. J Exp Med 1992, 176, 751-760.
-
(1992)
J Exp Med
, vol.176
, pp. 751-760
-
-
Dumont, F.J.1
Staruch, M.J.2
Koprak, S.L.3
-
89
-
-
0028930999
-
Nephrotoxicity of cyclosporin A and FK506: Inhibition of calcineurin phosphatase
-
Su Q, Weber L, Le Hir M, Zenke G, Ryffel B. Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. Renal Physiol Biochem 1995, 18, 128-139.
-
(1995)
Renal Physiol Biochem
, vol.18
, pp. 128-139
-
-
Su, Q.1
Weber, L.2
Le Hir, M.3
Zenke, G.4
Ryffel, B.5
-
90
-
-
0030560814
-
Transcription-modulating drugs: Mechanism and selectivity
-
Cai W, Hu L, Foulkes JG. Transcription-modulating drugs: mechanism and selectivity. Curr Opin Biotech 1996, 7, 608-615.
-
(1996)
Curr Opin Biotech
, vol.7
, pp. 608-615
-
-
Cai, W.1
Hu, L.2
Foulkes, J.G.3
-
91
-
-
0031897632
-
NF-kB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB. NF-kB and Rel proteins: Evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998, 16, 225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
92
-
-
0029874138
-
The NF-kB and IkB proteins: New discoveries and insights
-
Baldwin ASJ. The NF-kB and IkB proteins: new discoveries and insights. Annu Rev Immunol 1996, 14, 649-681.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-681
-
-
Baldwin, A.S.J.1
-
93
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB [see comments]. Nature 1997, 388, 548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
94
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IκB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IκB phosphorylation and NF-κB activation. Cell 1997, 91, 243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
95
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio F, Zhu H, Murray BW, et al. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation [see comments]. Science 1997, 278, 860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
-
96
-
-
0032583949
-
Differential regulation of IκB kinase alpha and beta by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
-
Nakano H, Shindo M, Sakon S, et al. Differential regulation of IκB kinase alpha and beta by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA 1998, 95, 3537-3542.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3537-3542
-
-
Nakano, H.1
Shindo, M.2
Sakon, S.3
-
97
-
-
0032583947
-
NF-κB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176
-
Ling L, Cao Z, Goeddel DV. NF-κB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. Proc Natl Acad Sci USA 1998, 95, 3792-3797.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3792-3797
-
-
Ling, L.1
Cao, Z.2
Goeddel, D.V.3
-
98
-
-
0031963751
-
Pro-inflammatory signaling: Last pieces in the NF-KB puzzle?
-
Baeuerle PA. Pro-inflammatory signaling: last pieces in the NF-KB puzzle? Current Biology 1998, 8, R19-R22.
-
(1998)
Current Biology
, vol.8
-
-
Baeuerle, P.A.1
-
99
-
-
0031801957
-
Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
-
O'Neill LA, Greene C. Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants. Journal of Leukocyte Biology 1998, 63, 650-657.
-
(1998)
Journal of Leukocyte Biology
, vol.63
, pp. 650-657
-
-
O'Neill, L.A.1
Greene, C.2
-
100
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
Burns K, Martinon F, Esslinger C, et al. MyD88, an adapter protein involved in interleukin-1 signaling. Journal of Biological Chemistry 1998, 273, 12203-12209.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
Martinon, F.2
Esslinger, C.3
-
101
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M, Ni J, Feng P, Dixit VM. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 1997, 278, 1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
102
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H, Henzel WJ, Shillinglaw W, Li S, Cao Z. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 1997, 7, 837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
103
-
-
0031901658
-
Inflammation: From molecular biology to clinic
-
Parnham MJ. Inflammation: From molecular biology to clinic. Drug News Perspect 1998, 11, 44-51.
-
(1998)
Drug News Perspect
, vol.11
, pp. 44-51
-
-
Parnham, M.J.1
-
104
-
-
0030838164
-
The caspase family of cysteine proteases
-
Thornberry NA. The caspase family of cysteine proteases. British Medical Bulletin 1997, 53, 478-490.
-
(1997)
British Medical Bulletin
, vol.53
, pp. 478-490
-
-
Thornberry, N.A.1
-
106
-
-
0031080248
-
The role of the Caspase family of cysteine proteases in apoptosis
-
Miller DK. The role of the Caspase family of cysteine proteases in apoptosis. Seminars in Immunology 1997, 9, 35-49.
-
(1997)
Seminars in Immunology
, vol.9
, pp. 35-49
-
-
Miller, D.K.1
-
107
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM. Caspases: the executioners of apoptosis. Biochemical Journal 1997, 326, 1-16.
-
(1997)
Biochemical Journal
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
108
-
-
0030965162
-
Cell death induction by TNF: A matter of self control
-
Wallach D. Cell death induction by TNF: a matter of self control. Trends Biochem Sci 1997, 22, 107-109.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 107-109
-
-
Wallach, D.1
-
109
-
-
0031805451
-
Death-inducing functions of ligands of the tumor necrosis factor family: A Sanhedrin verdict
-
Wallach D, Kovalenko AV, Varfolomeev EE, Boldin MP. Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict. Curr Opin Immunol 1998, 10, 279-288.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 279-288
-
-
Wallach, D.1
Kovalenko, A.V.2
Varfolomeev, E.E.3
Boldin, M.P.4
-
110
-
-
0032537836
-
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
-
Thome M, Hofmann K, Burns K, et al. Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr Biol 1998, 8, 885-888.
-
(1998)
Curr Biol
, vol.8
, pp. 885-888
-
-
Thome, M.1
Hofmann, K.2
Burns, K.3
-
113
-
-
0031587929
-
Novel homologues of CSBP/p38 MAP kinase: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
-
Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 1997, 235, 533-538.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 533-538
-
-
Kumar, S.1
McDonnell, P.C.2
Gum, R.J.3
Hand, A.T.4
Lee, J.C.5
Young, P.R.6
-
114
-
-
0029885419
-
Selective interaction of JNK protein kinase isoforms with transcription factors
-
Gupta S, Barrett T, Whitmarsh AJ, et al. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 1996, 15, 2760-2770.
-
(1996)
EMBO J
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
-
115
-
-
0030898417
-
Mitogen-activated protein kinase pathways
-
Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 1997, 9, 180-186.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 180-186
-
-
Robinson, M.J.1
Cobb, M.H.2
-
116
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 1996, 271, 24313-24316.
-
(1996)
J Biol Chem
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
117
-
-
0032479983
-
Mitogen and Stress Activated Protein kinase (MSK1), a novel two-kinase domain enzyme that is directly activated by MAPK and SAPK2/p38, and which may mediate the activation of CREB
-
In press
-
Deak M, Clifton AD, Lucocq JM, Alessi DR. Mitogen and Stress Activated Protein kinase (MSK1), a novel two-kinase domain enzyme that is directly activated by MAPK and SAPK2/p38, and which may mediate the activation of CREB. Embo J 1998, 17, In press.
-
(1998)
Embo J
, vol.17
-
-
Deak, M.1
Clifton, A.D.2
Lucocq, J.M.3
Alessi, D.R.4
-
118
-
-
0030977270
-
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
-
Fukunaga R, Hunter T. MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. Embo J 1997, 16, 1921-1933.
-
(1997)
Embo J
, vol.16
, pp. 1921-1933
-
-
Fukunaga, R.1
Hunter, T.2
-
119
-
-
0030977269
-
Mitogen-activated protein kinases activate the serine/threonine kinases Mnkl and Mnk2
-
Waskiewicz AJ, Flynn A, Proud CG, Cooper JA. Mitogen-activated protein kinases activate the serine/threonine kinases Mnkl and Mnk2. Embo J 1997, 16, 1909-1920.
-
(1997)
Embo J
, vol.16
, pp. 1909-1920
-
-
Waskiewicz, A.J.1
Flynn, A.2
Proud, C.G.3
Cooper, J.A.4
-
120
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda A, Rouse J, Doza YN, et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995, 364, 229-233.
-
(1995)
FEBS Lett
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
-
123
-
-
0030783156
-
The search for physiological substrates of MAP and SAP kinases in mammalian cells
-
Cohen P. The search for physiological substrates of MAP and SAP kinases in mammalian cells. Trends Cell Biol 1997, 7, 353-361.
-
(1997)
Trends Cell Biol
, vol.7
, pp. 353-361
-
-
Cohen, P.1
-
124
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
-
Alessi DA, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J Biol Chem 1995, 270, 27489-27494.
-
(1995)
J Biol Chem
, vol.270
, pp. 27489-27494
-
-
Alessi, D.A.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
125
-
-
14444279192
-
Identification of a Novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, et al. Identification of a Novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 1998, 273, 18623-18632.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
-
126
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372, 739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
-
127
-
-
0030924833
-
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
-
Young PR, McLaughlin MM, Kumar S, et al. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem 1997, 272, 12116-12121.
-
(1997)
J Biol Chem
, vol.272
, pp. 12116-12121
-
-
Young, P.R.1
McLaughlin, M.M.2
Kumar, S.3
-
128
-
-
12644277392
-
The Structural Basis for the Specificity of Pyridinylimidazole Inhibitors of p38 MAP kinase
-
Wilson KP, McCaffrey PG, Hsiao K, et al. The Structural Basis for the Specificity of Pyridinylimidazole Inhibitors of p38 MAP kinase. Chem Biol 1997, 4, 423-431.
-
(1997)
Chem Biol
, vol.4
, pp. 423-431
-
-
Kp, W.1
McCaffrey, P.G.2
Hsiao, K.3
-
130
-
-
0030954172
-
A Highly Specific Inhibitor of Human p38 MAP Kinase Binds in the ATP pocket
-
Tong L, Pav S, White DM, et al. A Highly Specific Inhibitor of Human p38 MAP Kinase Binds in the ATP pocket. Nat Struct Biol 1997, 4, 311-316.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 311-316
-
-
Tong, L.1
Pav, S.2
White, D.M.3
-
131
-
-
10744227768
-
Acquistion of sensitivity of stress-activated Protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket
-
Gum RJ, McLaughlin MM, Kumar S, et al. Acquistion of sensitivity of stress-activated Protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J Biol Chem 1998, 273, 15605-15610.
-
(1998)
J Biol Chem
, vol.273
, pp. 15605-15610
-
-
Gum, R.J.1
McLaughlin, M.M.2
Kumar, S.3
-
132
-
-
0032102902
-
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino acid substitution
-
Eyers PA, Craxton M, Morrice N, Cohen P, Goedert M. Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino acid substitution. Chem Biol 1998, 5, 321-328.
-
(1998)
Chem Biol
, vol.5
, pp. 321-328
-
-
Eyers, P.A.1
Craxton, M.2
Morrice, N.3
Cohen, P.4
Goedert, M.5
-
133
-
-
0029827366
-
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light
-
Price MA, Cruzalegui FH, Treisman R. The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light. Embo J 1996, 15, 6552-6563.
-
(1996)
Embo J
, vol.15
, pp. 6552-6563
-
-
Price, M.A.1
Cruzalegui, F.H.2
Treisman, R.3
-
135
-
-
0030894683
-
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
-
Han J, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 1997, 386, 296-299.
-
(1997)
Nature
, vol.386
, pp. 296-299
-
-
Han, J.1
Jiang, Y.2
Li, Z.3
Kravchenko, V.V.4
Ulevitch, R.J.5
-
136
-
-
0030703604
-
Regulation and function of the JNK subgroup of MAP kinases
-
Minden A, Karin M. Regulation and function of the JNK subgroup of MAP kinases. Biochim Biophys Acta 1997, 1333, F85-F104.
-
(1997)
Biochim Biophys Acta
, vol.1333
-
-
Minden, A.1
Karin, M.2
-
137
-
-
0030220456
-
p38/Rk is essential for stress-induced nuclear responses: Jnk/Sapks and c-Jun/Atf-2 phosphorylation are insufficient
-
Hazzalin CA, Cano E, Cuenda A, Barratt MJ, Cohen P, Mahadevan LC. p38/Rk is essential for stress-induced nuclear responses: Jnk/Sapks and c-Jun/Atf-2 phosphorylation are insufficient. Curr Biol 1996, 6, 1028-1031.
-
(1996)
Curr Biol
, vol.6
, pp. 1028-1031
-
-
Hazzalin, C.A.1
Cano, E.2
Cuenda, A.3
Barratt, M.J.4
Cohen, P.5
Mahadevan, L.C.6
-
138
-
-
0030660391
-
Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli
-
Hazzalin CA, Cuenda A, Cano E, Cohen P, Mahadevan LC. Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli. Oncogene 1997, 15, 2321-2331.
-
(1997)
Oncogene
, vol.15
, pp. 2321-2331
-
-
Hazzalin, C.A.1
Cuenda, A.2
Cano, E.3
Cohen, P.4
Mahadevan, L.C.5
-
139
-
-
0028886694
-
Activation of estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S, Endoh H, Masuhiro Y, et al. Activation of estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995, 270, 1491-1494.
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
-
140
-
-
0029133702
-
Requirement for MAP kinase (ERK2) activity in interferon a and interferon b stimulated gene expression through STAT proteins
-
David M, Petricoin EI, Benjamin C, Pine R, Weber MJ, Larner AC. Requirement for MAP kinase (ERK2) activity in interferon a and interferon b stimulated gene expression through STAT proteins. Science 1995, 269, 1721-1723.
-
(1995)
Science
, vol.269
, pp. 1721-1723
-
-
David, M.1
Petricoin, E.I.2
Benjamin, C.3
Pine, R.4
Weber, M.J.5
Larner, A.C.6
-
141
-
-
0029834762
-
Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase
-
Kumar S, Orsini MJ, Lee JC, McDonnell PC, Debouck C, Young PR. Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase. J Biol Chem 1996, 271, 30864-30869.
-
(1996)
J Biol Chem
, vol.271
, pp. 30864-30869
-
-
Kumar, S.1
Orsini, M.J.2
Lee, J.C.3
McDonnell, P.C.4
Debouck, C.5
Young, P.R.6
-
142
-
-
0029983730
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
-
Beyaert R, Cuenda A, Vanden Berghe W, et al. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. Embo J 1996, 15, 1914-1923.
-
(1996)
Embo J
, vol.15
, pp. 1914-1923
-
-
Beyaert, R.1
Cuenda, A.2
Vanden Berghe, W.3
-
144
-
-
0027217131
-
Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level
-
Young P, McDonnell P, Dunnington D, Hand A, Laydon J, Lee J. Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level. Agents & Actions 1993, 39, C67-C69.
-
(1993)
Agents & Actions
, vol.39
-
-
Young, P.1
McDonnell, P.2
Dunnington, D.3
Hand, A.4
Laydon, J.5
Lee, J.6
-
145
-
-
0029090620
-
Mechanism of action of bicyclic imidazoles defines a translational regulatory pathway on tumor necrosis factor α
-
Prichett W, Hand A, Sheilds J, Dunnington D. Mechanism of action of bicyclic imidazoles defines a translational regulatory pathway on tumor necrosis factor α. J Inflamm 1995, 45, 97-105.
-
(1995)
J Inflamm
, vol.45
, pp. 97-105
-
-
Prichett, W.1
Hand, A.2
Sheilds, J.3
Dunnington, D.4
-
146
-
-
0030881742
-
Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: Glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK
-
Swantek JL, Cobb MH, Geppert TD. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK. Mol Cell Biol 1997, 17, 6274-6282.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6274-6282
-
-
Swantek, J.L.1
Cobb, M.H.2
Geppert, T.D.3
-
147
-
-
0031057892
-
Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
-
Huot J, Houle F, Marceau F, Landry J. Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circ Res 1997, 80, 383-392.
-
(1997)
Circ Res
, vol.80
, pp. 383-392
-
-
Huot, J.1
Houle, F.2
Marceau, F.3
Landry, J.4
-
148
-
-
0029911368
-
p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPla2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPla2
-
Kramer RM, Roberts EF, Um SL, et al. p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPla2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPla2. J Biol Chem 1996, 271, 27723-27729.
-
(1996)
J Biol Chem
, vol.271
, pp. 27723-27729
-
-
Kramer, R.M.1
Roberts, E.F.2
Um, S.L.3
-
149
-
-
0030458635
-
Pharmacology of cytokine suppressive anti-inflammatory drug binding protein (CSBP), a novel stress induced kinase
-
Griswold DE, Young PR. Pharmacology of cytokine suppressive anti-inflammatory drug binding protein (CSBP), a novel stress induced kinase. Pharmacol Commun 1996, 7.
-
(1996)
Pharmacol Commun
, vol.7
-
-
De Griswold1
Young, P.R.2
-
150
-
-
0030426902
-
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
Badger AM, Bradbeer JN, Votta B, Lee JC, Adams JL, Griswold DE. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther 1996, 279, 1453-1461.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
Lee, J.C.4
Adams, J.L.5
Griswold, D.E.6
-
151
-
-
0031934170
-
Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models
-
Jackson JR, Bolognese B, Hillegass L, et al. Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models. J Pharmacol Exp Ther 1998, 284, 687-692.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 687-692
-
-
Jackson, J.R.1
Bolognese, B.2
Hillegass, L.3
-
152
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang DD, Kuan CY, Whitmarsh AJ, et al. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 1997, 389, 865-870.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
-
153
-
-
0030962347
-
The potential of farnesyltransferase inhibitors as cancer chemotherapeutics
-
Gibbs JB, Oliff A. The potential of farnesyltransferase inhibitors as cancer chemotherapeutics. Annual Review of Pharmacology & Toxicology 1997, 37, 143-166.
-
(1997)
Annual Review of Pharmacology & Toxicology
, vol.37
, pp. 143-166
-
-
Gibbs, J.B.1
Oliff, A.2
-
155
-
-
0032524357
-
New twists in gene regulation by glucocorticoid receptor: Is DNA binding dispensable?
-
Karin M. New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable? [comment]. Cell 1998, 93, 487-490.
-
(1998)
Cell
, vol.93
, pp. 487-490
-
-
Karin, M.1
-
156
-
-
0027934108
-
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1
-
Heck S, Kullman M, Gast A, et al. A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. Embo J 1994, 13, 4087-4095.
-
(1994)
Embo J
, vol.13
, pp. 4087-4095
-
-
Heck, S.1
Kullman, M.2
Gast, A.3
-
157
-
-
18144444807
-
DNA binding of the glucocorticoid receptor is not essential for survival
-
Reichardt HM, Kaestner KH, Tuckermann J, et al. DNA binding of the glucocorticoid receptor is not essential for survival. Cell 1998, 93, 531-541.
-
(1998)
Cell
, vol.93
, pp. 531-541
-
-
Reichardt, H.M.1
Kaestner, K.H.2
Tuckermann, J.3
-
158
-
-
0031474156
-
Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo
-
Vayssiere BM, Dupont S, Choquart A, et al. Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo. Mol Endocrinol 1997, 11, 1245-1255.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 1245-1255
-
-
Vayssiere, B.M.1
Dupont, S.2
Choquart, A.3
-
159
-
-
0031778177
-
Basic guide to the mechanisms of antiestrogen action
-
MacGregor JI, Jordan VC. Basic guide to the mechanisms of antiestrogen action. Pharmacol Reviews 1998, 50, 151-196.
-
(1998)
Pharmacol Reviews
, vol.50
, pp. 151-196
-
-
MacGregor, J.I.1
Jordan, V.C.2
-
160
-
-
0029798819
-
Estrogen promotes apoptosis of murine osteoclasts mediated by TGFb
-
Hughes DE, Dai A, Tifee JC, Li HH, Mundy GR, Boyce BF. Estrogen promotes apoptosis of murine osteoclasts mediated by TGFb. Nature Medicine 1996, 2, 1132-1136.
-
(1996)
Nature Medicine
, vol.2
, pp. 1132-1136
-
-
De Hughes1
Dai, A.2
Tifee, J.C.3
Li, H.H.4
Mundy, G.R.5
Boyce, B.F.6
-
161
-
-
0026516415
-
17b-estradiol inhibits IL-6 production by bone marrow-derived stromal cells and osteoblasts it vitro, a potential mechanism for the antosteoporotic effect of estrogens
-
Girasole G, Jilka RL, Passeri G, et al. 17b-estradiol inhibits IL-6 production by bone marrow-derived stromal cells and osteoblasts it vitro, a potential mechanism for the antosteoporotic effect of estrogens. J Clin Invest 1992, 89, 883-891.
-
(1992)
J Clin Invest
, vol.89
, pp. 883-891
-
-
Girasole, G.1
Jilka, R.L.2
Passeri, G.3
-
162
-
-
0032540013
-
PPARg in monocytes: Less pain, any gain?
-
Spiegelman BM. PPARg in monocytes: less pain, any gain? Cell 1998, 93, 153-155.
-
(1998)
Cell
, vol.93
, pp. 153-155
-
-
Spiegelman, B.M.1
-
163
-
-
0031888958
-
PPARg agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B. PPARg agonists inhibit production of monocyte inflammatory cytokines. Nature 1998, 391, 82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
164
-
-
0032520716
-
Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-κB activation
-
Kumar A, Dhawan S, Hardegen NJ, Aggarwal BB. Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-κB activation. Biochemical Pharmacology 1998, 55, 775-783.
-
(1998)
Biochemical Pharmacology
, vol.55
, pp. 775-783
-
-
Kumar, A.1
Dhawan, S.2
Hardegen, N.J.3
Aggarwal, B.B.4
-
165
-
-
0030773543
-
Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBalpha phosphorylation, and degradation
-
Chaturvedi MM, Kumar A, Darnay BG, Chainy GB, Agarwal S, Aggarwal BB. Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBalpha phosphorylation, and degradation. Journal of Biological Chemistry 1997, 272, 30129-30134.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 30129-30134
-
-
Chaturvedi, M.M.1
Kumar, A.2
Darnay, B.G.3
Chainy, G.B.4
Agarwal, S.5
Aggarwal, B.B.6
-
166
-
-
0031982964
-
Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IκB alpha phosphorylation and degradation
-
Schwenger P, Alpert D, Skolnik EY, Vilcek J. Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IκB alpha phosphorylation and degradation. Molecular & Cellular Biology 1998, 18, 78-84.
-
(1998)
Molecular & Cellular Biology
, vol.18
, pp. 78-84
-
-
Schwenger, P.1
Alpert, D.2
Skolnik, E.Y.3
Vilcek, J.4
-
167
-
-
0026080801
-
Thalidomide selectively inhibits tumor necrosis factor a production by stimulated human monocytes
-
Sampaio EP, Sarno EP, Galilly R, Cohn ZA, Kaplan G. Thalidomide selectively inhibits tumor necrosis factor a production by stimulated human monocytes. J Exp Med 1991, 173, 699-703.
-
(1991)
J Exp Med
, vol.173
, pp. 699-703
-
-
Sampaio, E.P.1
Sarno, E.P.2
Galilly, R.3
Cohn, Z.A.4
Kaplan, G.5
-
168
-
-
0027304271
-
The influence of thalidomide on the clinical and immunologic manifestation of erythema nodosum leprosum
-
Sampaio EP, Kaplan G, Miranda A, et al. The influence of thalidomide on the clinical and immunologic manifestation of erythema nodosum leprosum. J Infect Dis 1993, 168, 408-414.
-
(1993)
J Infect Dis
, vol.168
, pp. 408-414
-
-
Sampaio, E.P.1
Kaplan, G.2
Miranda, A.3
-
170
-
-
0030882762
-
Taming TNF: Strategies to restrain this proinflammatory cytokine
-
Eigler A, Sinha B, Hartmann G, Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunology Today 1997, 18, 487-492.
-
(1997)
Immunology Today
, vol.18
, pp. 487-492
-
-
Eigler, A.1
Sinha, B.2
Hartmann, G.3
Endres, S.4
-
171
-
-
0028639541
-
Small Molecular Weight TNF Biosynthesis Inhibitors: Strategies and Prospectives
-
Lee JC, Prabhakar U, Griswold DE, Dunnington D, Young PR, Badger A. Small Molecular Weight TNF Biosynthesis Inhibitors: Strategies and Prospectives. Circul Shock 1995, 44, 97-103.
-
(1995)
Circul Shock
, vol.44
, pp. 97-103
-
-
Lee, J.C.1
Prabhakar, U.2
Griswold, D.E.3
Dunnington, D.4
Young, P.R.5
Badger, A.6
|