Caspases: Killer proteases

Trends in Biochemical Sciences

Volumn 22, Issue 8, 1997, Pages 299-306

  Nicholson, Donald W ^a   Thornberry, Nancy A ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; ENZYME INHIBITOR; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEINASE; UNCLASSIFIED DRUG;

APOPTOSIS; CELL DEATH; ENZYME ACTIVITY; ENZYME STRUCTURE; EVOLUTION; GENE EXPRESSION; HUMAN; MUTATION; NEMATODE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CYSTEINE ENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; SUBSTRATE SPECIFICITY;

EUKARYOTA;

EID: 0030814675     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(97)01085-2     Document Type: Review

References (57)

1. Thompson, C. B. (1995) Science 267, 1455-1462
2. Thornberry, N. A. et al. (1992) Nature 356, 768-774
3. Cerretti, D. P. et al. (1992) Science 256, 97-100
4. Yuan, J. et al. (1993) Cell 75, 641-652
5. Xue, D., Shaham, S. and Horvitz, H. R. (1996) Genes Dev. 10, 1073-1083
6. Thornberry, N. A., Rosen, A. and Nicholson, D. W. (1997) Adv. Pharmacol. 41, 155-177
7. Li, P. et al. (1995) Cell 80, 401-411
8. Kuida, K. et al. (1995) Science 267, 2000-2003
9. Gu, Y. et al (1997) Science 275, 206-209
10. Ghayur, T. et al. (1997) Nature 386, 619-623
11. Alnemri, E. S. et al. (1996) Cell 87, 171
12. Kumar, S. et al. (1994) Genes Dev. 8, 1613-1626
13. Wang, L. et al. (1994) Cell 78, 739-750
14. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E. S. (1994) J. Biol. Chem. 269, 30761-30764
15. Nicholson, D. W. et al. (1995) Nature 376, 37-43
16. Tewari, M. et al. (1995) Cell 81, 801-809
17. Munday, N. A. et al. (1995) J. Biol. Chem. 270. 15870-15876
18. Faucheu, C. et al. (1995) EMBO J. 14, 1914-1922
19. Kamens, J. et al. (1995) J. Biol. Chem. 270, 15250-15256
20. Faucheu, C. et al. (1996) Eur. J. Biochem. 236, 207-213
21. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E. S. (1995) Cancer Res. 55, 2737-2742
22. Fernandes-Alnemri, T. et al. (1995) Cancer Res. 55, 6045-6052
23. Duan, H. et al. (1996) J. Biol. Chem. 271, 1621-1625
24. Lippke, J. A. et al. (1996) J. Biol. Chem. 271, 1825-1828
25. Boldin, M. P., Goncharov, T. M., Goitsev, Y. V. and Wallach, D. (1996) Cell 85, 803-815
26. Muzio, M. et al. (1996) Cell 85, 817-827
27. Srinivasula, S. M. et al. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14486-14491
28. Duan, H. et al. (1996) J. Biol. Chem. 271. 16720-16724
29. Srinivasula, S. M. et al. (1996) J. Biol. Chem. 271, 27099-27106
30. Fernandes-Alnemri, T. et al. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7464-7469
31. Vincez, C. and Dixit, V. M. (1997) J. Biol. Chem. 272, 6578-6583
32. Wilson, K. P. et al. (1994) Nature 370, 270-275
33. Walker, N. P. C. et al. (1994) Cell 78. 343-352
34. Rotonda, J. et al. (1996) Nat. Struct. Biol. 3, 619-625
35. Rano, T. A. et al. (1997) Chem. Biol. 4. 149-155
36. Thornberry, N. A. et al. J. Biol. Chem. (in press)
37. Thornberry, N. A., Miller, D. K. and Nicholson, D. W. (1995) Perspect. Drug Des. Discovery 2, 389-399
38. Ray, C. A. (1992) Cell 69, 597-604
39. Zhou, Q. et al. (1997) J. Biol. Chem. 272. 7797-7800
40. Xue, D. and Horvitz, H. R. (1995) Nature 377, 248-251
41. Bump, N. J. et al. (1995) Science 269, 1885-1888
42. Deveraux, Q. et al. Nature (in press)
43. Roy, N. et al. (1995) Cell 80, 167-178
44. Song, Z., McCall, K. and Steller, H. (1997) Science 275, 536-540
45. Fraser, A. and Evan, G. (1997) EMBO J. 16. 2805-2813
46. Kuida, K. et al. (1996) Nature 384, 368-372
47. Lazebnik. Y. A. et al. (1994) Nature 371, 346-347
48. Casciola-Rosen, L. et al. (1996) J. Exp. Med. 183, 1957-1964
49. Goldberg, Y. P. et al. (1996) Nat. Genet. 13. 442-449
50. Darmon, A. J., Nicholson, D. W. and Bleackley, R. C. (1995) Nature 377, 446-448
51. Martin S. J. et al. (1996) EMBO J. 15, 2407-2416
52. Duan, H. and Dixit, V. M. (1997) Nature 385, 86-89
53. Van Criekinge, W. et al. (1996) J. Biol. Chem. 271, 27245-27248
54. Chinnaiyan, A. et al. (1997) Science 275, 1122-1126
55. Wu, D., Wallen, H. D. and Nunez, G. (1997) Science 275, 1126-1129
56. Spector, M. S. et al. (1997) Nature 385, 653-656
57. Irmler, M. et al. (1997) FEBS Lett. 406, 189-190