메뉴 건너뛰기




Volumn 63, Issue 6, 1998, Pages 650-657

Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants

Author keywords

IRAK; N protein; NF B; p38 MAP kinase; Toll; TRAF6

Indexed keywords

INTERLEUKIN 1;

EID: 0031801957     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.63.6.650     Document Type: Article
Times cited : (507)

References (53)
  • 1
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C. A. (1996) Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 2
    • 0028930858 scopus 로고
    • Towards an understanding of the signal transduction pathways of interleukin 1
    • O'Neill, L. A. J. (1995) Towards an understanding of the signal transduction pathways of interleukin 1. Biochim. Biophys. Acta 1266, 31-44.
    • (1995) Biochim. Biophys. Acta , vol.1266 , pp. 31-44
    • O'Neill, L.A.J.1
  • 7
    • 0025774776 scopus 로고
    • Drosophila Toll and IL-1 receptor
    • Gay, N., Keith, F. (1991) Drosophila Toll and IL-1 receptor. Nature 351, 355-356.
    • (1991) Nature , vol.351 , pp. 355-356
    • Gay, N.1    Keith, F.2
  • 8
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre, B., Nicolas, E., Michaut, L., Reichart, J-M., Hoffmann, J. A. (1996) The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichart, J.-M.4    Hoffmann, J.A.5
  • 9
    • 0029009910 scopus 로고
    • Molecular cloning and characterisation of a second subunit of the interleukin 1 receptor complex
    • Greenfeeder, S. A., Nunes, P., Kwee, L., Labow, M., Chizzonite, R. A., Ju, G. (1995) Molecular cloning and characterisation of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270, 13757-13765.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13757-13765
    • Greenfeeder, S.A.1    Nunes, P.2    Kwee, L.3    Labow, M.4    Chizzonite, R.A.5    Ju, G.6
  • 10
    • 0029989325 scopus 로고    scopus 로고
    • IL-1Rrp is a novel receptor-like molecule similar to the Type I interleukin 1 receptor and its homologue T1/ST2 and IL-1RAcP
    • Parnet, P., Garka, K. E., Bonnert, T., Dower, S. K., Sims, J. E. (1996) IL-1Rrp is a novel receptor-like molecule similar to the Type I interleukin 1 receptor and its homologue T1/ST2 and IL-1RAcP. J. Biol. Chem. 271, 3967-3970.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3967-3970
    • Parnet, P.1    Garka, K.E.2    Bonnert, T.3    Dower, S.K.4    Sims, J.E.5
  • 11
    • 0030663332 scopus 로고    scopus 로고
    • The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense
    • Williams, M. J., Rodriguez, A., Kimbrell, D. A., Eldon, E. D. (1997) The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J. 16, 6120-6130.
    • (1997) EMBO J. , vol.16 , pp. 6120-6130
    • Williams, M.J.1    Rodriguez, A.2    Kimbrell, D.A.3    Eldon, E.D.4
  • 13
    • 0030476449 scopus 로고    scopus 로고
    • Plant disease resistence genes: Function meets structure
    • Bent, A. (1996) Plant disease resistence genes: function meets structure. Plant Cell 8, 1757-1771.
    • (1996) Plant Cell , vol.8 , pp. 1757-1771
    • Bent, A.1
  • 14
    • 0029867832 scopus 로고    scopus 로고
    • Chromosomal localization of Til, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14
    • Taguchi, T., Mitcham, J., Dower, S. K., Sims, J. E., Testa, J. R. (1996) Chromosomal localization of Til, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14. Genomics 32, 486-488.
    • (1996) Genomics , vol.32 , pp. 486-488
    • Taguchi, T.1    Mitcham, J.2    Dower, S.K.3    Sims, J.E.4    Testa, J.R.5
  • 15
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R., Preston-Hurlburt, P., Janeway, C. A. (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388, 394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 17
    • 0029145684 scopus 로고
    • Evidence from sequence information that the interleukin 1 receptor is a transmembrane GTPase
    • Hopp, T. P. (1995) Evidence from sequence information that the interleukin 1 receptor is a transmembrane GTPase. Protein Sci. 4, 1851-1854.
    • (1995) Protein Sci. , vol.4 , pp. 1851-1854
    • Hopp, T.P.1
  • 18
    • 0025219908 scopus 로고
    • Interleukin-1 signal transduction: Increased GTP binding and hydrolysis in membranes of a murine thymoma line (EL4)
    • O'Neill, L. A. J., Bird, T. A., Gearing, A. J. H., Saklatvala, J. (1990) Interleukin-1 signal transduction: increased GTP binding and hydrolysis in membranes of a murine thymoma line (EL4). J. Biol. Chem. 265, 3146-3152.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3146-3152
    • O'Neill, L.A.J.1    Bird, T.A.2    Gearing, A.J.H.3    Saklatvala, J.4
  • 19
    • 0030938198 scopus 로고    scopus 로고
    • The interleukin 1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of IRAK and SAP kinases
    • Wesche, H., Korherr, C., Kracht, M., Falk, W., Resch, K., Martin, M. U. (1997) The interleukin 1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of IRAK and SAP kinases. J. Biol. Chem. 272, 7727-7731.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7727-7731
    • Wesche, H.1    Korherr, C.2    Kracht, M.3    Falk, W.4    Resch, K.5    Martin, M.U.6
  • 20
    • 2642601904 scopus 로고    scopus 로고
    • IL-1 receptor internalisation requires the cytoplasmic part of the IL-1 receptor accessory protein
    • Abstract 228
    • Korherr, C., Hofmeister, R., Falk, W. (1997) IL-1 receptor internalisation requires the cytoplasmic part of the IL-1 receptor accessory protein. Cytokine 9, 946 (Abstract 228).
    • (1997) Cytokine , vol.9 , pp. 946
    • Korherr, C.1    Hofmeister, R.2    Falk, W.3
  • 21
    • 0030662372 scopus 로고    scopus 로고
    • Recruitment of IRAK to the interleukin 1 complex requires interleukin 1 receptor accessory protein
    • Huang, J., Gao, X., Li, S., Cao, Z. (1997) Recruitment of IRAK to the interleukin 1 complex requires interleukin 1 receptor accessory protein. Proc. Natl. Acad. Sci. USA 94, 12829-12832.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12829-12832
    • Huang, J.1    Gao, X.2    Li, S.3    Cao, Z.4
  • 22
    • 2642636686 scopus 로고    scopus 로고
    • Two hybrid interaction between IL-1RAcP and IRAK suggests that IL-1AcP is responsible for the recruitment of IRAK to the IL-1/IL-1RAcP complex
    • Abstract 118
    • Volpe, F., Clatworthy, J., Kaptein, A., Maschera, B., Wilson, R., Griggin, A., Ray, K. (1997) Two hybrid interaction between IL-1RAcP and IRAK suggests that IL-1AcP is responsible for the recruitment of IRAK to the IL-1/IL-1RAcP complex. Cytokine 9, 119 (Abstract 118).
    • (1997) Cytokine , vol.9 , pp. 119
    • Volpe, F.1    Clatworthy, J.2    Kaptein, A.3    Maschera, B.4    Wilson, R.5    Griggin, A.6    Ray, K.7
  • 25
    • 0007468174 scopus 로고    scopus 로고
    • Soluble IL-18 receptor in human urine: Characterisation and purification
    • Abstract 294
    • Novick, D., Dinarello, C. A., Rubinstein, M. (1997) Soluble IL-18 receptor in human urine: characterisation and purification. Cytokine 9, 295 (Abstract 294).
    • (1997) Cytokine , vol.9 , pp. 295
    • Novick, D.1    Dinarello, C.A.2    Rubinstein, M.3
  • 27
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., Karin, M. (1997) A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388, 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 28
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterisation of IκB kinase
    • Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D., Cao, Z., Rothe, M. (1997) Identification and characterisation of IκB kinase. Cell 90, 373-383.
    • (1997) Cell , vol.90 , pp. 373-383
    • Regnier, C.H.1    Song, H.Y.2    Gao, X.3    Goeddel, D.4    Cao, Z.5    Rothe, M.6
  • 29
    • 0030611595 scopus 로고    scopus 로고
    • IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
    • Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., Goeddel, D. V. (1997) IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278, 866-869.
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 31
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin, N. L., Boldin, M. P., Kovalenko, A. V., Wallach, D. (1997) MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385, 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 32
    • 0028240827 scopus 로고
    • Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells
    • Martin, M., Bol, G. F., Eriksson, A., Resch, K., Brigelius-Flohe, R. (1994) Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells. Eur. J. Immunol. 24, 1566-1571.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1566-1571
    • Martin, M.1    Bol, G.F.2    Eriksson, A.3    Resch, K.4    Brigelius-Flohe, R.5
  • 33
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin 1 receptor
    • Cao, Z., Henzel, W. J., Gao, X. (1996) IRAK: a kinase associated with the interleukin 1 receptor. Science 271, 1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 34
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin 1
    • Cao, Z., Xiong, J., Takeuchi, M., Kurama, T., Goeddel, D. V. (1996) TRAF6 is a signal transducer for interleukin 1. Nature 383, 443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 35
    • 2642598815 scopus 로고    scopus 로고
    • IRAK and TRAF6 in the induction of IL-2 by IL-1 in T lymphocytes
    • Abstract 151
    • Greene, C., O'Neill, L. A. J. (1997) IRAK and TRAF6 in the induction of IL-2 by IL-1 in T lymphocytes. Cytokine 9, 927 (Abstract 151).
    • (1997) Cytokine , vol.9 , pp. 927
    • Greene, C.1    O'Neill, L.A.J.2
  • 36
    • 2642654044 scopus 로고    scopus 로고
    • Effects of overexpression of IRAK on NF-κB-mediated IL2 production and stress activated protein kinase activity
    • Abstract 121
    • Martin, M. U., Wesche, H., Lang, D., Knop, J. (1997) Effects of overexpression of IRAK on NF-κB-mediated IL2 production and stress activated protein kinase activity. Cytokine 9, 920 (Abstract 121).
    • (1997) Cytokine , vol.9 , pp. 920
    • Martin, M.U.1    Wesche, H.2    Lang, D.3    Knop, J.4
  • 37
    • 0030868909 scopus 로고    scopus 로고
    • The interleukin 1 receptor-associated kinase is degraded by proteasome following its phosphorylation
    • Yamin, T. T., Miller, D. K. (1997) The interleukin 1 receptor-associated kinase is degraded by proteasome following its phosphorylation. J. Biol. Chem. 272, 21540-21547.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21540-21547
    • Yamin, T.T.1    Miller, D.K.2
  • 38
    • 0030694108 scopus 로고    scopus 로고
    • IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
    • Muzio, M., Ni, J., Feng, P., Dixit, V. M. (1997) IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278, 1612-1615.
    • (1997) Science , vol.278 , pp. 1612-1615
    • Muzio, M.1    Ni, J.2    Feng, P.3    Dixit, V.M.4
  • 40
    • 0030054290 scopus 로고    scopus 로고
    • Interleukin 1 receptors and signal transduction
    • O'Neill, L. A. J. (1996) Interleukin 1 receptors and signal transduction. Biochem. Soc. Trans. 24, 207-211.
    • (1996) Biochem. Soc. Trans. , vol.24 , pp. 207-211
    • O'Neill, L.A.J.1
  • 41
    • 2642590780 scopus 로고    scopus 로고
    • p38 activation as a key event in the induction of IL-2 by IL-1 in T lymphocytes
    • Abstract 398
    • Matthews, J. S., O'Neill, L. A. J. (1996) p38 activation as a key event in the induction of IL-2 by IL-1 in T lymphocytes. Immunology 89 (Abstract 398).
    • (1996) Immunology , vol.89
    • Matthews, J.S.1    O'Neill, L.A.J.2
  • 43
    • 2642700773 scopus 로고    scopus 로고
    • A new MAP kinase kinase (MKK7) is the major activator of JNK/SAPK activated by interleukin 1 in vivo
    • Abstract 114
    • Finch, A., Holland, P., Cooper, J., Saklatvala, J., Kracht, M. (1997) A new MAP kinase kinase (MKK7) is the major activator of JNK/SAPK activated by interleukin 1 in vivo. Cytokine 9, 918 (Abstract 114).
    • (1997) Cytokine , vol.9 , pp. 918
    • Finch, A.1    Holland, P.2    Cooper, J.3    Saklatvala, J.4    Kracht, M.5
  • 44
    • 0028015872 scopus 로고
    • Interleukin 1 activates a novel protein kinase that results in the phosphorylation of hsp27
    • Freshney, N. W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Saklatvala, J. (1994) Interleukin 1 activates a novel protein kinase that results in the phosphorylation of hsp27. Cell 78, 1039-1049.
    • (1994) Cell , vol.78 , pp. 1039-1049
    • Freshney, N.W.1    Rawlinson, L.2    Guesdon, F.3    Jones, E.4    Cowley, S.5    Saklatvala, J.6
  • 45
    • 0028858089 scopus 로고
    • Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast
    • Kumar, S., McLaughlin, M. M., McDonnell, P. C., Lee, J. C., Livi, G. P., Young, P. R. (1995) Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast. J. Biol Chem. 270, 29043-29046.
    • (1995) J. Biol Chem. , vol.270 , pp. 29043-29046
    • Kumar, S.1    McLaughlin, M.M.2    McDonnell, P.C.3    Lee, J.C.4    Livi, G.P.5    Young, P.R.6
  • 46
    • 0030783156 scopus 로고    scopus 로고
    • The search for physiological substrates of MAP kinase and SAP kinases in mammalian cells
    • Cohen, P. (1997) The search for physiological substrates of MAP kinase and SAP kinases in mammalian cells. Trends Cell Biol. 7, 353-361.
    • (1997) Trends Cell Biol. , vol.7 , pp. 353-361
    • Cohen, P.1
  • 48
    • 0029834762 scopus 로고    scopus 로고
    • Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase
    • Kumar, S., Orsini, M. J., Lee, J. C., McDonnell, P. C., Debouck, C., Young, P. R. (1996) Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase. J. Biol. Chem. 271, 30864-30869.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30864-30869
    • Kumar, S.1    Orsini, M.J.2    Lee, J.C.3    McDonnell, P.C.4    Debouck, C.5    Young, P.R.6
  • 49
    • 0030773533 scopus 로고    scopus 로고
    • Dual specificity of the IL-1- and TNF-activated β casein kinase
    • Guesdon, F., Knight, C. G., Rawlinson, L. M., Saklatvala, J. (1997) Dual specificity of the IL-1- and TNF-activated β casein kinase. J. Biol. Chem. 272, 30017-30024.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30017-30024
    • Guesdon, F.1    Knight, C.G.2    Rawlinson, L.M.3    Saklatvala, J.4
  • 52
    • 2642604016 scopus 로고    scopus 로고
    • Interleukin 1 signaling: Synergy with Rac1 and PI3 kinase and evidence for the involvement of a low molecular weight G protein
    • Abstract 115
    • O'Neill, L. A. J., Matthews, J. S., Pålsson, E., Jeffries, C., Brennan, P., Cantrell, D. A. (1997) Interleukin 1 signaling: synergy with Rac1 and PI3 kinase and evidence for the involvement of a low molecular weight G protein. Cytokine 9, 918 (Abstract 115).
    • (1997) Cytokine , vol.9 , pp. 918
    • O'Neill, L.A.J.1    Matthews, J.S.2    Pålsson, E.3    Jeffries, C.4    Brennan, P.5    Cantrell, D.A.6
  • 53
    • 0038982945 scopus 로고    scopus 로고
    • IL-1 and PDGF synergistically activate JNK.SAPK via signaling pathways that are independently modulated by Rac and CDC42
    • Abstract 148
    • Davis, W., Stephens, L., Hawkins, P., Saklatvala, J. (1997) IL-1 and PDGF synergistically activate JNK.SAPK via signaling pathways that are independently modulated by Rac and CDC42. Cytokine 9, 926 (Abstract 148).
    • (1997) Cytokine , vol.9 , pp. 926
    • Davis, W.1    Stephens, L.2    Hawkins, P.3    Saklatvala, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.