Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists

Journal of Medicinal Chemistry

Volumn 39, Issue 25, 1996, Pages 4867-4870

  Samanen, J M ^a   Ali, F E ^a   Barton, L S ^a   Bondinell, W E ^a   Burgess, J L ^a   Callahan, J F ^a   Calvo, R R ^a   Chen, W ^a   Chen, L ^a   Erhard, K ^a   Feuerstein, G ^a   Heys, R ^a   Hwang S , M ^a   Jakas, D R ^a   Keenan, R M ^a   Ku, T W ^a   Kwon, C ^a   Lee, C P ^a   Miller, W H ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 OXO 1,4 BENZODIAZEPINE DERIVATIVE; ANTITHROMBOCYTIC AGENT; BENZODIAZEPINE DERIVATIVE; FIBRINOGEN RECEPTOR ANTAGONIST; LOTRAFIBAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; DOG; DOSE RESPONSE; DRUG DESIGN; DRUG MECHANISM; HEART INFARCTION; INTRADUODENAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; REVIEW; STROKE; THROMBOCYTE AGGREGATION; THROMBOSIS;

ADMINISTRATION, ORAL; BENZODIAZEPINONES; HUMANS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX;

EID: 0029775672     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960558a     Document Type: Review

References (0)