Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

Journal of Biological Chemistry

Volumn 272, Issue 18, 1997, Pages 12116-12121

  Young, Peter R ^a   McLaughlin, Megan M ^a   Kumar, Sanjay ^a   Kassis, Shouki ^a   Doyle, Michael L ^a   McNulty, Dean ^a   Gallagher, Timothy F ^a   Fisher, Seth ^a   McDonnell, Peter C ^a   Carr, Steven A ^a   Huddleston, Michael J ^a   Seibel, George ^a   Porter, Terence G ^a   Livi, George P ^a   Adams, Jerry L ^a   Lee, John C ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; BINDING SITE; ENZYME INHIBITION; ESCHERICHIA COLI; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOSINE; ADENOSINE TRIPHOSPHATE; AFFINITY LABELS; AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALORIMETRY; CLONING, MOLECULAR; CROSS-LINKING REAGENTS; ENZYME INHIBITORS; ESCHERICHIA COLI; HELA CELLS; HUMANS; IMIDAZOLES; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASES; MUTAGENESIS, SITE-DIRECTED; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI;

EID: 0030924833     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.18.12116     Document Type: Article

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