A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

Nature Structural Biology

Volumn 4, Issue 4, 1997, Pages 311-316

  Tong, Liang ^a   Pav, Susan ^a   White, Della M ^a   Rogers, Sheri ^a   Crane, Kathy M ^a   Cywin, Charles L ^a   Brown, Maryanne L ^a   Pargellis, Christopher A ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME INHIBITOR COMPLEX; ENZYME SPECIFICITY; HYDROGEN BOND; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RECOMBINANT PROTEINS;

EID: 0030954172     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0497-311     Document Type: Article

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