Optimal diets for prevention of coronary heart disease

JAMA

Volumn 288, Issue 20, 2002, Pages 2569-2578

  Hu, Frank B ^a,b   Willett, Walter C ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CARBOHYDRATE; CHOLESTEROL; FISH OIL; FOLIC ACID; GLUCOSE; MINERAL; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROTEIN; UNSATURATED FATTY ACID; VITAMIN;

ADULT; ARTICLE; BODY WEIGHT; DIET THERAPY; FAT INTAKE; FEMALE; FIBER; FRUIT; GLUCOSE BLOOD LEVEL; GRAIN; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; NUT; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SMOKING CESSATION; VEGETABLE;

EID: 0037184418     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.288.20.2569     Document Type: Article

References (147)

1. Anitschkow NN. A history of experimentation on arterial atherosclerosis in animals. In: Bleumenthal HT, ed. Cowdry's Arteriosclerosis: A Survey of the Problem. 2nd Ed. Springfield, III: Charles C Thomas; 1967:21-44.
2. McGill HC. The relationship of dietary cholesterol to serum cholesterol concentration and to atherosclerosis in man. Am J Clin Nutr. 1979;32:2664-2702.
3. Gordon T. The diet-heart idea: Outline of a history. Am J Epidemiol. 1988;127:220-225.
4. Keys A. Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease. Cambridge, Mass: Harvard University Press; 1980.
5. Kato H, Tillotson J, Nichamen MZ, Rhoads GG, Hamilton HB. Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: Serum lipids and diet. Am J Epidemiol. 1973;97:372-385.
6. Hu FB, Willett WC. Diet, nutrition, and coronary heart disease. In: Douglas PS, ed. Cardiovascular Health and Disease in Women. 2nd Ed. Philadelphia: WB Saunders; 2002:71-92.
7. Keys A, Parlin RW. Serum-cholesterol response to changes in dietary lipids. Am J Clin Nutr. 1966;19:175-181.
8. Hegsted DM, McGandy RB, Myers ML, Stare FJ. Quantitative effects of dietary fat on serum cholesterol in man. Am J Clin Nutr. 1965;17:281-295.
9. Hegsted DM, Ausman LM, Johnson JA, Dallal GE. Dietary fat and serum lipids: An evaluation of the experimental data [published correction appears in Am J Clin Nutr. 1993;58:245]. Am J Clin Nutr. 1993;57:875-883.
10. Mensink RP, Katan MB. Effect of dietary fatty acids on serum lipids and lipoproteins: A meta-analysis of 27 trials. Arterioscler Thromb. 1992;12:911-919.
11. Yu S, Derr J, Etherton TD, Kris-Etherton P. Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterolemic. Am J Clin Nutr. 1995;61:1129-1139.
12. Hu FB, van Dam RM, Liu S. Diet and risk of type II diabetes: The role of types of fat and carbohydrate. Diabetologia. 2001;44:805-817.
13. Summers LK, Fielding BA, Bradshaw HA, et al. Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity. Diabetologia. 2002;45:369-377.
14. Meyer KA, Kushi LH, Jacobs DR Jr, Folsom AR. Dietary fat and incidence of type 2 diabetes in older Iowa women. Diabetes Care. 2001;24:1528-1535.
15. Salmeron J, Hu FB, Manson JE, et al. Dietary fat intake and risk of type 2 diabetes in women. Am J Clin Nutr. 2001;73:1019-1026.
16. Mensink RP, Katan MB. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. N Engl J Med. 1990;323:439-445.
17. Zock PL, Katan MB. Hydrogenation alternatives: Effects of trans fatty acids and stearic acid versus linoleic acid on serum lipids and lipoproteins in humans. J Lipid Res. 1992;33:399-410.
18. Nestel P, Noakes M, Belling BE. Plasma lipoprotein and Lp[a] changes with substitution of elaidic acid for oleic acid in the diet. J Lipid Res. 1992;33:1029-1036.
19. Judd JT, Clevidence BA, Muesing RA, Wittes J, Sunkin ME, Podczasy JJ. Dietary trans fatty acids: Effects of plasma lipids and lipoproteins of healthy men and women. Am J Clin Nutr. 1994;59:861-868.
20. Judd JT, Baer DJ, Clevidence BA, Kris-Etherton P, Muesing RA, Iwane M. Dietary cis and trans monounsaturated and saturated FA and plasma lipids and lipoproteins in men. Lipids. 2002;37:123-131.
21. Lichtenstein AH, Ausman LM, Jalbert SM, Schaffer EJ. Effects of different forms of dietary hydrogenated fats on serum lipoprotein cholesterol levels. N Engl J Med. 1999;340:1933-1940.
22. Aro A, Jauhiainen M, Partanen R, Salminen I, Mutanen M. Stearic acid, trans fatty acids, and dairy fat: Effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjects. Am J Clin Nutr. 1997;65:1419-1426.
23. Sundram K, Ismail A, Hays KC, Jeyamalar R, Pathmanathan R. Trans (elaidic) fatty acids adversely affect the lipoprotein profile relative to specific saturated fatty acids in humans. J Nutr. 1997;127:514S-520S.
24. Lichtenstein AH, Ausman LM, Carrasco W, Jenner JL, Ordovas JM, Schaefer EJ. Hydrogenation impairs the hypolipidemic effect of corn oil in humans: Hydrogenation, trans fatty acids, and plasma lipids. Arterioscler Thromb. 1993;13:154-161.
25. Ascherio A, Katan MB, Zock PL, Stampfer MJ, Willett WC. Trans fatty acids and coronary heart disease. N Engl J Med. 1999;340:1994-1998.
26. Katan MB, Zock PL. Trans fatty acids and their effects on lipoproteins in humans. Annu Rev Nutr. 1995;15:473-493.
27. de Roos NM, Bots ML, Siebelink E, Schouten E, Katan MB. Flow-mediated vasodilation is not impaired when HDL-cholesterol is lowered by substituting carbohydrates for monounsaturated fat. Br J Nutr. 2001;86:181-188.
28. Hill EG, Johnson SB, Lawson LD, Mahfouz MM, Holman RT. Perturbation of the metabolism of essential fatty acids by dietary hydrogenated vegetable oil. Proc Natl Acad Sci U S A. 1982;79:953-957.
29. Kinsella JE, Bruckner G, Mai J, Shimp J. Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: An overview. Am J Clin Nutr. 1981;34:2307-2318.
30. Lovejoy JC. Dietary fatty acids and insulin resistance. Curr Atheroscler Rep. 1999;1:215-220.
31. Kromhout D, Menotti A, Bloemberg B, et al. Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: The Seven Countries Study. Prev Med. 1995;24:308-315.
32. Garcia-Palmieri MR, Sorlie P, Tillotson J, Costas R Jr, Cordero E, Rodriguez M. Relationship of dietary intake to subsequent coronary heart disease incidence: The Puerto Rico Heart Health Program. Am J Clin Nutr. 1980;33:1818-1827.
33. Gordon T, Kagan A, Garcia-Palmieri M, et al. Diet and its relation to coronary heart disease and death in three populations. Circulation. 1981;63:500-515.
34. Shekelle RB, Shryock AM, Paul O, et al. Diet, serum cholesterol, and death from coronary heart disease: The Western Electric Study. N Engl J Med. 1981;304:65-70.
35. McGee DL, Reed DM, Yano K, Kagan A, Tillotson J. Ten-year incidence of coronary heart disease in the Honolulu Heart Program: Relationship to nutrient intake. Am J Epidemiol. 1984;119:667-676.
36. Kushi LH, Lew RA, Stare FJ, et al. Diet and 20-year mortality from coronary heart disease: The Ireland-Boston Diet-Heart Study. N Engl J Med. 1985;312:811-818.
37. Kromhout D, de Lezenne Coulander C. Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men: The Zutphen Study. Am J Epidemiol. 1984;119:733-741.
38. Ascherio A, Rimm EB, Giovannucci EL, Spiegelman D, Stampfer MJ, Willett WC. Dietary fat and risk of coronary heart disease in men: Cohort follow up study in the United States. BMJ. 1996;313:84-90.
39. Pietinen P, Ascherio A, Korhonen P, et al. Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men: The ATBC Study. Am J Epidemiol. 1997;145:876-887.
40. Hu FB, Stampfer MJ, Manson JE, et al. Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med. 1997;337:1491-1499.
41. Willett WC. Nutritional Epidemiology. 2nd Ed. New York, NY: Oxford University Press; 1998.
42. Hu FB, Stampfer MJ, Rimm EB, et al. A prospective study of egg consumption and risk of cardiovascular disease in men and women. JAMA. 1999;281:1387-1394.
43. Oomen C, Ocke MC, Feskens JM, van Erp-Barrt MJ, Kok FJ, Kromhout D. Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: A prospective population-based study. Lancet. 2001;357:746-751.
44. Lemaitre RN, King IB, Raghunathan TE, et al. Cell membrane trans-fatty acids and the risk of primary cardiac arrest. Circulation. 2002;105:697-701.
45. Roberts TL, Wood DA, Riemersma RA, Gallagher PJ, Lampe FC. Trans isomers of oleic and linoleic acids in adipose tissue and sudden cardiac death. Lancet. 1995;345:278-282.
46. Dayton S, Pearce ML, Hashimoto S, Dixon WJ, Tomiyasu U. A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis. Circulation. 1969;40(suppl 2):1-63.
47. Turpeinen O, Karvonen MJ, Pekkarinen M, Miettinen M, Elosuo R, Paavilainen E. Dietary prevention of coronary heart disease: The Finnish Mental Hospital Study. Int J Epidemiol. 1979;8:99-118.
48. Leren P. The Oslo Diet-Heart Study. Acta Med Scand. 1966;466(suppl):5-92.
49. Leren P. The Oslo Diet-Heart Study: Eleven-year report. Circulation. 1970;42:935-942.
50. Morris JN, Ball KP, Antonis A, et al. Controlled trial of soya-bean oil in myocardial infarction. Lancet. 1968;2:693-699.
51. Frantz ID Jr, Dawson EA, Ashman PL, et al. Test of effect of lipid lowering by diet on cardiovascular risk: The Minnesota Coronary Survey. Arteriosclerosis. 1989;9:129-135.
52. Ball KP, Hanington E, McAllen PM, et al. Low-fat diet in myocardial infarction: A controlled trial. Lancet. 1965;2:501-504.
53. Burr ML, Fehily AM, Gilbert JF, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and Reinfarction Trial (DART). Lancet. 1989;2:757-761.
54. Kang JX, Leaf A. Antiarrhythmic effects of poly-unsaturated fatty acids: Recent studies. Circulation. 1996;94:1774-1780.
55. Connor SL, Connor WE. Are fish oils beneficial in the prevention and treatment of coronary artery disease? Am J Clin Nutr. 1997;66(4 suppl):1020S-1031S.
56. Kromhout D, Bosscheiter EB, de Lezenne Coulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med. 1985;312:1205-1209.
57. Marckmann P, Gronbaek M. Fish consumption and coronary heart disease mortality: A systematic review of prospective cohort studies. Eur J Clin Nutr. 1999;53:585-590.
58. Oomen CM, Feskens EJ, Rasanen L, et al. Fish consumption and coronary heart disease mortality in Finland, Italy, and the Netherlands. Am J Epidemiol. 2000;151:999-1006.
59. Rissanen T, Voutilainen S, Nyyssonen K, Lakka TA, Salonen JT. Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: The Kuopio Ischaemic Heart Disease Risk Factor Study. Circulation. 2000;102:2677-2679.
60. Hu FB, Bronner L, Willett WC, et al. Fish and omega-3 fatty acid and risk of coronary heart disease in women. JAMA. 2002;287:1815-1821.
61. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett WC, et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med. 2002;346:1113-1118.
62. Tavani A, Pelucchi C, Negri E, Bertuzzi M, La Vecchia C. n-3 polyunsaturated fatty acids, fish, and nonfatal acute myocardial infarction. Circulation. 2001;104:2269-2272.
63. Hu FB, Stampfer MJ, Manson JE, et al. Dietary intake of alpha-linolenic acid and risk of ischemic heart disease among women. Am J Clin Nutr. 1999;69:890-897.
64. Dolecek TA. Epidemiological evidence of relationships between dietary polyunsaturated fatty acids and mortality in the Multiple Risk Factor Intervention Trial. Proc Soc Exp Biol Med. 1992;200:177-182.
65. Oomen CM, Ocke MC, Feskens EJ, Kok FJ, Kromhout D. α-linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: The Zutphen Elderly Study. Am J Clin Nutr. 2001;74:457-463.
66. GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results from the GISSI-Prevenzione trial. Lancet. 1999;354:447-455.
67. Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: Time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002;105:1897-1903.
68. Singh RB, Niaz MA, Sharma JP, Kumar R, Rastogi V, Moshiri M. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: The Indian Experiment of Infarct Survival 4. Cardiovasc Drugs Ther. 1997;11:485-491.
69. de Lorgeril M, Renaud S, Mamelle N, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet. 1994;343:1454-1459.
70. de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study. Circulation. 1999;99:779-785.
71. US Department of Agriculture/US Department of Health and Human Services. Nutrition and Your Health: Dietary Guidelines for Americans. Washington, DC: US Government Printing Office; 2000. Homes and Garden Bulletin 232.
72. Krauss RM, Eckel RH, Howard B, et al. AHA dietary guidelines revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation. 2000;102:2284-2299.
73. Jenkins DJ, Wolever TM, Taylor RH, et al. Glycemic index of foods: A physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981;34:362-366.
74. Wolever TM, Jenkins DJ, Jenkins AL, Josse RG. The glycemic index: Methodology and clinical implications. Am J Clin Nutr. 1991;54:846-854.
75. Jenkins DJ, Kendall CW, Augustin LS, et al. Glycemic index: Overview of implications in health and disease. Am J Clin Nutr. 2002;76:266S-273S.
76. Salmeron J, Manson JE, Stampfer MJ, Colditz GA, Wing AL, Willett WC. Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. JAMA. 1997;277:472-477.
77. Salmeron J, Ascherio A, Rimm EB, et al. Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care. 1997;20:545-550.
78. Liu S, Manson JE, Stampfer MJ, et al. Dietary glycemic load assessed by food frequency questionnaire in relation to plasma high-density lipoprotein cholesterol and fasting triglycerides in postmenopausal women. Am J Clin Nutr. 2001;73:560-566.
79. Liu S, Willett WC, Stampfer MJ, et al. A prospective study of dietary glycemic load and risk of myocardial infarction in women. Am J Clin Nutr. 2000;71:1455-1461.
80. Jeppesen J, Schaaf P, Jones C, Zhou MY, Chen YD, Reaven GM. Effects of low-fat, high-carbohydrate diets on risk factors for ischemic heart disease in postmenopausal women [published correction appears in Am J Clin Nutr. 1997;66:437]. Am J Clin Nutr. 1997;65:1027-1033.
81. Liu S, Buring JE, Sesso HD, Rimm EB, Willett WC, Manson JE. A prospective study of dietary fiber intake and risk of cardiovascular disease among women. J Am Coll Cardiol. 2002;39:49-56.
82. Rimm EB, Ascherio A, Giovannucci E, Spiegelman D, Stampfer MI, Willett WC. Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men. JAMA. 1996;275:447-451.
83. Pietinen P, Rimm EB, Korhonen P, et al. Intake of dietary fiber and risk of coronary heart disease in a cohort of Finnish men: The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Circulation. 1996;94:2720-2727.
84. Wolk AM, Manson JE, Stampfer MJ, et al. Long-term intake of dietary fiber and decreased risk of coronary heart disease among women. JAMA. 1999;281:1998-2004.
85. Jacobs DR, Pereira MA, Meyer KA, Kushi LH. Fiber from whole grains, but not refined grains, is inversely associated with all-cause mortality in older women: The Iowa Women's Health Study. J Am Coll Nutr. 2000;19(3 suppl):326S-330S.
86. Rimm E, Willett W, Hu FB, et al. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA. 1998;279:359-365.
87. Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study. Circulation. 2001;103:2674-2680.
88. Bazzano LA, He J, Ogden LG, et al. Dietary intake of folate and risk of stroke in US men and women: NHANES-I Epidemiologic Follow-up Study. Stroke. 2002;33:1183-1189.
89. Loria CM, Ingram DD, Feldman JJ, Wright JD, Madans JH. Serum folate and cardiovascular disease mortality among US men and women. Arch Intern Med. 2000;160:3258-3262.
90. Voutilainen S, Lakka TA, Porkkala-Sarataho E, Rissanen T, Kaplan GA, Salonen JT. Low serum folate concentrations are associated with an excess incidence of acute coronary events: The Kuopio Ischaemic Heart Disease Risk Factor Study. Eur J Clin Nutr. 2000;54:424-428.
91. Vermeulen EG, Stenhouwer CD, Twisk JW, et al. Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: A randomized, placebo-controlled trial. Lancet. 2000;355:517-522.
92. Schnyder G, Roffi M, Pin R, et al. Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. N Engl J Med. 2001;345:1593-1600.
93. Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: The Swiss Heart Study: A randomized controlled trial. JAMA. 2002;288:973-979.
94. Bostom AG, Selhub J, Jacques PF, Rosenberg IH. Power shortage: Clinical trials testing the "homocysteine hypothesis" against a background of folic acid-fortified cereal grain flour. Ann Intern Med. 2001;135:133-137.
95. Hu FB, Stampfer MJ, Manson JE, et al. Dietary saturated fat and their food sources in relation to the risk of coronary heart disease in women. Am J Clin Nutr. 1999;70:1001-1008.
96. Fraser GE, Sabate J, Beeson WL, Strahan TM. A possible protective effect of nut consumption on risk of coronary heart disease: The Adventist Health Study. Arch Intern Med. 1992;152:1416-1424.
97. Fraser GE, Shavlik DJ. Risk factors for all-cause and coronary heart disease mortality in the oldest-old: The Adventist Health Study. Arch Intern Med. 1997;157:2249-2258.
98. Hu FB, Stampfer MJ, Manson JE, et al. Frequent nut consumption and risk of coronary heart disease: Prospective cohort study. BMJ. 1998;317:1341-1345.
99. Brown L, Sacks F, Rosner B, Willett WC. Nut consumption and risk of coronary heart disease in patients with myocardial infarction [abstract]. FASEB J. 1999;13:A4332.
100. Ellsworth JL, Kushi LH, Folsom AR. Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: The Iowa Women's Health Study. Nutr Metab Cardiovasc Dis. 2001;11:372-377.
101. Albert CM, Gaziano JM, Willett WC, Manson JE. Nut consumption and decreased risk of sudden cardiac death in the physicians' health study. Arch Intern Med. 2002;162:1382-1387.
102. Kris-Etherton PM, Zhao G, Binkoski AE, Coval SM, Etherton TD. The effects of nuts on coronary heart disease risk. Nutr Rev. 2001;59:103-111.
103. Knekt P, Reunanen A, Jarvinen R, Seppanen R, Heliovaara M, Aromaa A. Antioxidant vitamin intake and coronary mortality in a longitudinal population study. Am J Epidemiol. 1994;139:1180-1189.
104. Gillman MW, Cupples LA, Gagnon D, et al. Protective effect of fruits and vegetables on development of stroke in men. JAMA. 1995;273:1113-1117.
105. Gaziano JM, Manson JE, Branch LG, Colditz GA, Willett WC, Buring JE. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann Epidemiol. 1995;5:255-260.
106. Joshipura KJ, Ascherio A, Manson JE, et al. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA. 1999;282:1233-1239.
107. Joshipura KJ, Hu FB, Manson JE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med. 2001;134:1106-1114.
108. Liu S, Manson JE, Lee IM, et al. Fruit and vegetable intake and risk of cardiovascular disease: The Women's Health Study. Am J Clin Nutr. 2000;72:922-928.
109. Liu S, Lee IM, Ajani U, Cole SR, Buring JE, Manson JE. Intake of vegetables rich in carotenoids and risk of coronary heart disease in men: The Physicians' Health Study. Int J Epidemiol. 2001;30:130-135.
110. Bazzano LA, He J, Odgden LG, et al. Fruit and vegetable intake and risk of cardiovascular disease in US adults: The first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Am J Clin Nutr. 2002;76:93-99.
111. Jacobs DR, Meyer KA, Kushi LH, Folsom AR. Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: The Iowa Women's Health Study. Am J Clin Nutr. 1998;68:248-257.
112. Liu S, Stampfer MJ, Hu FB, et al. Whole-grain consumption and risk of coronary heart disease: Results from the Nurses' Health Study. Am J Clin Nutr. 1999;70:412-419.
113. Liu S, Manson JE, Stampfer MI, et al. Whole grain consumption and risk of ischemic stroke in women: A prospective study. JAMA. 2000;284:1534-1540.
114. Hu FB. Dietary pattern analysis: A new direction in nutritional epidemiology. Curr Opin Lipidol. 2002;13:3-9.
115. Hu FB, Rimm EB, Stampfer MJ, Ascherio A, Spiegelman D, Willett WC. Prospective study of majot dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr. 2000;72:912-921.
116. Fung TT, Willett WC, Stampfer MJ, Manson JE, Hu FB. Dietary patterns and risk of coronary heart disease in women Arch Intern Med. 2001;161:1857-1862.
117. Singh RB, Rastogi SS, Verman R, et al. Randomised controlled trial of cardioprotective diet in patients with recent acute myocardial infarction: Results of one year follow up. BMJ. 1992;304:1015-1019.
118. Appel L, Moore TJ, Obrazanek E, for the DASH Collaborative Research Group. A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med. 1997;336:1117-1124.
119. Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med. 2001;344:3-10.
120. Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willett WC. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med. 2000;343:16-22.
121. Hu FB, Stampfer MJ, Manson JE, et al. Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women. N Engl J Med. 2000;343:530-537.
122. Miettinen TA, Strandberg TE. Implications of recent results of long term multifactorial primary prevention of cardiovascular diseases. Ann Med. 1992;24:85-89.
123. Hjermann I, Velve Byre K, Holme I, Leren P. Effect of diet and smoking intervention on the incidence of coronary heart disease: Report from the Oslo Study Group of a randomised trial in healthy men. Lancet. 1981;2:1303-1310.
124. Ornish D, Scherwitz LW, Billings JH, et al. Intensive lifestyle changes for reversal of coronary heart disease [published correction appears in JAMA. 1999;281:1380]. JAMA. 1998;280:2001-2007.
125. Zock PL, Katan MB. Linoleic acid intake and cancer risk: A review and meta-analysis. Am J Clin Nutr. 1998;68:142-153.
126. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation. 2002;105:1874-1875.
127. Berry EM. Dietary fatty acids in the management of diabetes mellitus. Am J Clin Nutr. 1997;66(4 suppl):991S-997S.
128. Hu FB, Manson JE, Willett WC. Types of dietary fat and risk of coronary heart disease: A critical review. J Am Coll Nutr. 2001;20:5-19.
129. Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med. 1995;333:276-282.
130. Wolfe BM. Potential role of raising dietary protein intake for reducing risk of atherosclerosis. Can J Cardiol. 1995;11(suppl G):127G-131G.
131. Hu FB, Stampfer MJ, Manson JE, et al. Dietary protein and risk of coronary heart disease in women. Am J Clin Nutr. 1999;70:221-227.
132. Law M. Plant sterol and stanol margarines and health. BMJ. 2000;320:861-864.
133. Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study. Lancet. 1993;342:1007-1011.
134. Knekt P, Jarvinen R, Reunanen A, Maatela J. Flavonoid intake and coronary mortality in Finland: A cohort study. BMJ. 1996;312:478-481.
135. Yochum L, Kushi LH, Meyer K, Folsom AR. Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal women [published correction appears in Am J Epidemiol. 1999;150:432]. Am J Epidemiol. 1999;149:943-949.
136. Geleijnse JM, Launer LJ, Van der Kuip DA, Hofman A, Witteman JC. Inverse association of tea and flavonoid intakes with incident myocardial infarction: The Rotterdam Study. Am J Clin Nutr. 2002;75:880-886.
137. Rimm EB, Katan MB, Ascherio A, Stampfer MJ, Willlett WC. Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Ann Intern Med. 1996;125:384-389.
138. Hertog MG, Sweetnam PM, Fehily AM, Elwood PC, Kromhout D. Antioxidant flavonols and ischemic heart disease in a Welsh population of men: The Caerphilly Study. Am J Clin Nutr. 1997;65:1489-1494.
139. Pruthi S, Allison TG, Hensrud DD. Vitamin E supplementation in the prevention of coronary heart disease. Mayo Clin Proc. 2001;76:1131-1136.
140. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20536 high-risk individuals: A randomized placebo-controlled trial. Lancet. 2002;360:23-33.
141. Pirozzo S, Summerbell C, Cameron C, Glasziou P. Advice on Low-Fat Diets for Obesity (Cochrane Review on CD-ROM). Oxford, England: Cochrane Library, Update Software; 2002; issue 2.
142. Willett WC. Dietary fat plays a major role in obesity: No. Obes Rev. 2002;3:59-68.
143. McManus K, Antinoro L, Sacks F. A randomized controlled trial of a moderate-fat, low-energy diet compared with a low fat, low-energy diet for weight loss in overweight adults. Int J Obes Relat Metab Disord. 2001;25:1503-1511.
144. Ludwig DS. The glycemic index: Physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. JAMA. 2002;287:2414-2423.
145. Skov AR, Toubro S, Ronn B, Holm L, Astrup A. Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity. Int J Obes Relat Metab Disord. 1999;23:528-536.
146. Baba NH, Sawaya S, Torbay N, Habbal Z, Azar S, Hashim SA. High protein vs high carbohydrate hypoenergetic diet for the treatment of obese hyperinsulinemic subjects. Int J Obes Relat Metab Disord. 1999;23:1202-1206.
147. Zemel MB. Regulation of adiposity and obesity risk by dietary calcium: Mechanisms and implications. J Am Coll Nutr. 2002;21:146S-151S.