-
2
-
-
0023105114
-
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.-H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
6
-
-
0027477463
-
-
(1993)
J. Biol. Chem
, vol.268
, pp. 3072-3083
-
-
Roher, A.E.1
Lowenson, J.D.2
Clarke, S.3
Wolkow, C.4
Wang, R.5
Cotter, R.J.6
Reardon, I.7
Zurcher-Neely, H.A.8
Heinrikson, R.L.9
Ball, M.J.10
Greenberg, B.D.11
-
10
-
-
0033595706
-
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.5
Denis, P.6
Teplow, D.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.16
Biere, A.17
Curran, E.18
Burgess, T.19
Louis, J.20
Collins Treanor, J.21
Rogers, G.22
Citron, M.23
more..
-
11
-
-
0033518264
-
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.2
Shuck, M.3
Miao, H.4
Tory, M.5
Pauley, A.6
Brashler, J.7
Stratman, N.8
Mathews, W.9
Buhl, A.10
Carter, D.11
Tomasselli, A.12
Parodi, L.13
Heinrikson, R.14
Gurney, M.15
-
12
-
-
0033518251
-
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.2
Barbour, R.3
Basi, G.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops Suomensaari, S.14
Wang, S.15
Walker, D.16
Zhao, J.17
McConlogue, L.18
John, V.19
-
13
-
-
0033382226
-
-
(1999)
Mol. Cell. Neurosci
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.3
Tew, D.4
Meek, T.5
Chapman, C.6
Gloger, I.7
Murphy, K.8
Southan, C.9
Ryan, D.10
Smith, T.11
Simmons, D.12
Walsh, F.13
Dingwall, C.14
Christie, G.15
-
15
-
-
0027327267
-
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MachLachlan, D.R.9
Alberts, M.J.10
-
16
-
-
0027194791
-
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell P.C., Jr.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
17
-
-
0009288026
-
-
(1998)
Nat. Genetics
, vol.19
, pp. 314-316
-
-
Blacker, D.1
Wilcox, M.2
Laird, N.3
Rodes, L.4
Horvath, S.5
Go, R.6
Perry, R.7
Watson, B.8
Bassett, S.9
McInnis, M.10
Albert, M.11
Hyman, B.12
Tanzi, R.13
-
18
-
-
0026879650
-
-
(1992)
Nature Genet
, vol.1
, pp. 218-221
-
-
Hendriks, L.1
van Duijn, C.M.2
Cras, P.3
Cruts, M.4
Van Hul, W.5
van Harskamp, F.6
Warren, A.7
McInnis, M.G.8
Antonarakis, S.E.9
Martin, J.-J.10
Hofman, A.11
Van Broeckhoven, C.12
-
19
-
-
0025296269
-
-
(1990)
Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
Power, M.D.4
Lieberburg, I.5
van Duinen, S.G.6
Bots, G.T.A.M.7
Luyendijk, W.8
Frangione, B.9
-
22
-
-
9844261165
-
-
(1997)
Human Mol. Genet
, vol.6
, pp. 2087-2089
-
-
Eckman, C.1
Mehta, N.2
Crook, R.3
Perez-tur, J.4
Prihar, G.5
Pfeiffer, E.6
Graff-Radford, N.7
Hinder, P.8
Yager, D.9
Zenk, B.10
Refolo, L.11
Prada, C.12
Younkin, S.13
Hutton, M.14
Hardy, J.15
-
23
-
-
0026088977
-
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
26
-
-
0029004341
-
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi Roses, A.D.15
Fraser, P.E.16
Rommens, J.M.17
St. George-Hyslop, P.H.18
-
27
-
-
0029087026
-
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, H.6
Yu, C.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
28
-
-
0029150716
-
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
Anderson, L.4
Goddard, A.B.5
Weber, J.L.6
Bird, T.D.7
Schellenberg, G.D.8
-
29
-
-
0029101491
-
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holamn, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini Rommens, J.M.14
St. George-Hyslop, P.H.15
-
32
-
-
6844255860
-
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 43-51
-
-
Cruts, M.1
van Duijn, C.M.2
Backhovens, H.3
Van den Broeck, M.4
Wehnert, A.5
Serneels, S.6
Sherrington, R.7
Hutton, M.8
Hardy, J.9
St George-Hyslop, P.H.10
Hofman, A.11
Van Broeckhoven, C.12
-
33
-
-
0009135744
-
-
(1995)
Neuroreport
, pp. 7
-
-
Perez-Tur, J.1
Froelich, S.2
Prihar, G.3
Crook, R.4
Baker, M.5
Duff, K.6
Wragg, M.7
Busfield, F.8
Lendon, C.9
Clark, R.F.10
Roques, P.11
Fuldner, R.A.12
Johnston Roberts, G.W.13
Rossor, M.14
Adams, M.D.15
Hardy, J.16
Goate, A.17
Lannfelt, L.18
Hutton, M.19
-
34
-
-
0031893609
-
-
(1998)
Am. J. Hum. Genet
, vol.62
, pp. 70-76
-
-
Tysoe, C.1
Whittaker, J.2
Xuereb, J.3
Caims, N.J.4
Cruts, M.5
Van Broeckhovern, C.6
Wilcock, G.7
Rubinsztein, D.C.8
-
35
-
-
6844240203
-
-
(1998)
NeuroReport
, vol.9
, pp. 217-221
-
-
Wisniewski, T.1
Dowjat, W.K.2
Buxbaum, J.D.3
Khorkova, O.4
Efthimiopoulos, S.5
Kulczycki, J.6
Lojkowska, W.7
Wegiel, J.8
Wisniewski, H.M.9
Frangione, B.10
-
37
-
-
0028099612
-
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11993-11997
-
-
Citron, M.1
Vigo-Pelfrey, C.2
Teplow, D.B.3
Miller, C.4
Schenk, D.5
Johnston, J.6
Winblad, B.7
Venizelos, N.8
Lannfelt, L.9
Selkoe, D.J.10
-
39
-
-
0028322017
-
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.-D.3
Odaka, A.4
Otvos L., Jr.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
40
-
-
0028985574
-
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little McConlogue, L.18
Montoya-Zavala, M.19
Mucke, L.20
Paganini, L.21
Penniman, E.22
Power, M.23
Schenk, D.24
Seubert, P.25
Snyder, B.26
Soriano, F.27
Tan, H.28
Vitale, J.29
Wadsworth, S.30
Wolozin, B.31
Zhao, J.32
more..
-
41
-
-
0029742199
-
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Ekman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
43
-
-
15844425969
-
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Rotovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
44
-
-
16044373524
-
-
(1996)
Nature Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
45
-
-
16044365171
-
-
(1996)
Nature Med
, vol.2
, pp. 1146-1148
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
Lendon, C.L.4
Ossa, J.5
Saido, T.C.6
Yamaguchi, H.7
Ruiz, A.8
Martinez, A.9
Madrigal, L.10
Hincapie, L.11
Arango, L.J.C.12
Anthony, D.C.13
Koo, E.H.14
Goate, A.M.15
Selkoe, D.J.16
Arango, V.J.C.17
-
46
-
-
12644258498
-
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
Iwatsubo, T.11
Obata, K.12
-
47
-
-
16944365745
-
-
(1997)
J. Biol. Chem
, vol.272
, pp. 7977-7982
-
-
Xia, W.1
Zhang, J.2
Kholodenko, D.3
Citron, M.4
Podlisny, M.B.5
Teplow, D.B.6
Haass, C.7
Seubert, P.8
Koo, E.H.9
Selkoe, D.J.10
-
48
-
-
16944362157
-
-
(1997)
Nature Med
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenka, D.11
Motter, R.12
Sherrington Schenk, D.13
Fraser, P.14
St George-Hyslop, P.15
Selkoe, D.J.16
-
49
-
-
16044366039
-
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.5
Pereztur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
50
-
-
0030293676
-
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.1
Thinakaran, G.2
Eckman, C.3
Lee, M.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.11
Wang, R.12
Seeger, M.13
Levey, A.14
Gandy, S.15
Copeland, N.16
Jenkins, N.17
Price, D.18
Younkin, S.19
Sisodia, S.20
more..
-
51
-
-
0031710159
-
-
(1998)
Neurobiol. Disease
, vol.5
, pp. 107-116
-
-
Citron, M.1
Eckman, C.B.2
Diehl, T.S.3
Corcoran, C.4
Ostaszewski, B.L.5
Xia, W.6
Levesque, G.7
St George Hyslop, P.8
Younkin, S.G.9
Selkoe, D.J.10
-
53
-
-
0033551099
-
-
(1999)
Biochemistry
, vol.38
, pp. 4720-4727
-
-
Wolfe, M.W.1
Xia, W.2
Moore, C.L.3
Leatherwood, D.D.4
Ostaszewski, B.5
Rahmati, T.6
Donkor, I.O.7
Selkoe, D.J.8
-
55
-
-
0030599284
-
-
(1996)
Biochem. Biophys. Res. Commun
, vol.227
, pp. 730-735
-
-
Maruyama, K.1
Tomita, T.2
Shinozaki, K.3
Kume, H.4
Asada, H.5
Saido, T.C.6
Ishiura, S.7
Iwatsubo, T.8
Obata, K.9
-
58
-
-
0032556859
-
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Gundula, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
62
-
-
0033214070
-
-
(1999)
J. Biol. Chem
, vol.274
, pp. 28669-28673
-
-
Steiner, H.1
Duff, K.2
Capell, A.3
Romig, H.4
Grim, M.5
Lincoln, S.6
Hardy, J.7
Yu, X.8
Picciano, M.9
Fechteler, K.10
Citron, M.11
Kopan, R.12
Pesold, B.13
Keck, S.14
Baader, M.15
Tomita, T.16
Iwatsubo, T.17
Baumeister, R.18
Haass, C.19
-
64
-
-
0033535504
-
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
65
-
-
0033579505
-
-
(1999)
J. Biol. Chem
, vol.274
, pp. 36801-36807
-
-
Ray, W.J.1
Yao, M.2
Mumm, J.3
Schroeter, E.4
Saftig, P.5
Wolfe, M.6
Selkoe, D.7
Kopan, R.8
Goate, A.M.9
-
67
-
-
13044278313
-
-
(1999)
Proc. Natl. Acad. Sci., USA
, vol.96
, pp. 11872-11877
-
-
Herreman, A.1
Hartmann, D.2
Annaert, W.3
Saftig, P.4
Craessaerts, K.5
Serneels, L.6
Umans, L.7
Schrijvers, V.8
Checler, F.9
Vanderstichele, H.10
Baekelandt, V.11
Dressel, R.12
Cupers, P.13
Huylebroeck, D.14
Zwijsen, A.15
Van Leuven, F.16
De Strooper, B.17
-
69
-
-
0033014046
-
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3263-3268
-
-
Ray, W.J.1
Yao, M.2
Nowotny, P.3
Mumm, J.4
Zhang, W.5
Wu, J.6
Kopan, R.7
Goate, A.M.8
-
70
-
-
0034255029
-
-
(2000)
PNAS
, vol.97
, pp. 9299-9304
-
-
Xia, W.1
Ray, W.J.2
Ostaszewski, B.L.3
Rahmati, T.4
Kimberly, W.T.5
Wolfe, M.S.6
Zhang, J.7
Goate, A.M.8
Selkoe, D.J.9
-
73
-
-
0034621824
-
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.M.1
Xu, M.2
Lai, M.T.3
Huang, Q.4
Castro, J.L.5
DiMuzio-Mower, J.6
Harrison, T.7
Lellis, C.8
Nadin, A.9
Neduvelil, J.G.10
Register, R.B.11
Sardana, M.K.12
Shearman, M.S.13
Smith, A.L.14
Shi, X.P.15
Yin, K.C.16
Shafer, J.A.17
Gardell, S.J.18
-
74
-
-
0034602419
-
-
(2000)
J. Biol. Chem
, vol.275
, pp. 34086-34091
-
-
Seiffert, D.1
Bradley, J.D.2
Rominger, C.M.3
Rominger, D.H.4
Yang, F.5
Meredith, J.6
Wang, Q.7
Roach, A.H.8
Thompson, L.A.9
Spitz, S.M.10
Higaki, J.N.11
Prakash Cordell, B.12
Stern, A.M.13
Olson, R.E.14
Zaczek, R.15
-
75
-
-
0033780472
-
-
(2000)
Nature Cell Biology
, vol.2
, pp. 428-434
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Diehl, T.S.4
Moore, C.L.5
Tsai, J.-Y.6
Rahmati, T.7
Xia, W.8
Selkoe, D.J.9
Wolfe, M.S.10
-
81
-
-
0033575224
-
-
(1999)
J. Biol. Chem
, vol.274
, pp. 20499-20504
-
-
Durkin, J.T.1
Murthy, S.2
Husten, E.J.3
Trusko, S.P.4
Savage, M.J.5
Rotella, D.P.6
Greenberg, B.D.7
Siman, R.8
-
82
-
-
0027535901
-
-
(1993)
J. Med. Chem
, vol.36
, pp. 468-478
-
-
Shiosaki, K.1
Tasker, A.S.2
Sullivan, G.M.3
Sorensen, B.K.4
von Geldern, T.W.5
Wu-Wong, J.R.6
Marselle, C.A.7
Opgenorth, T.J.8
-
83
-
-
0030769091
-
-
(1997)
Nature Med
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.2
Bruhl, B.3
Tienari, P.4
Ida, N.5
Allsop, D.6
Roberts, G.7
Masters, C.8
Dotti, C.9
Unsicker, K.10
Beyreuther, K.11
-
84
-
-
0030769092
-
-
(1997)
Nature Med
, vol.3
, pp. 1021-1023
-
-
Cook, D.1
Forman, M.2
Sung, J.3
Leight, S.4
Kolson, D.5
Iwatsubo, T.6
Lee, V.7
Doms, R.8
-
90
-
-
0024792446
-
-
(1989)
Proc. Natl. Acad. Sci. U.S.A
, vol.86
, pp. 9752-9756
-
-
Dreyer, G.B.1
Metcalf, B.W.2
Tomaszek T.A., Jr.3
Carr, T.J.4
Chandler A.C. III5
Hyland, L.6
Fakhoury, S.A.7
Magaard, V.W.8
Moore, M.L.9
Strickler, J.E.10
Debouck, C.11
Meek, T.D.12
-
92
-
-
0033598365
-
-
(1999)
J. Med. Chem
, vol.42
, pp. 3889-3898
-
-
Higaki, J.N.1
Chakravarty, S.2
Bryant, C.M.3
Lisa, R.4
Cowart, A.5
Harden, P.6
Scardina, J.M.7
Mavunkel, B.8
Luedtke, G.R.9
Cordell, B.10
-
98
-
-
0027050188
-
-
(1992)
Protein Sci
, vol.1
, pp. 322-328
-
-
Veerapandian, B.1
Cooper, J.B.2
Sali, A.3
Blundell, T.L.4
Rosati, R.L.5
Dominy, B.W.6
Damon, D.B.7
Hoover, D.J.8
-
101
-
-
0034254585
-
-
(2000)
Biochemistry
, vol.39
, pp. 8698-8704
-
-
Shearman, M.S.1
Beher, D.2
Clarke, E.E.3
Lewis, H.4
Harrison, T.5
Hunt, P.6
Nadin, A.7
Smith, A.L.8
Stevenson, G.9
Castro, J.L.10
-
102
-
-
0026010259
-
-
(1991)
J. Med. Chem
, vol.34
, pp. 2852-2857
-
-
De Solms, S.J.1
Giuliani, E.A.2
Guare, J.P.3
Vacca, J.P.4
Sanders, W.M.5
Graham, S.L.6
Wiggins, J.M.7
Darke, P.L.8
Sigal, I.S.9
Zugay, J.A.10
Emini, E.A.11
Schleif, W.A.12
Quintero, J.C.13
Anderson, P.S.14
Huff, J.R.15
-
103
-
-
0035977071
-
-
(2001)
J. Biol. Chem
, vol.276
, pp. 45394-45402
-
-
Beher, D.1
Wrigley, J.D.J.2
Nadin, A.3
Evin, G.4
Masters, C.L.5
Harrison, T.6
Castrol, J.L.7
Shearman, M.S.8
-
104
-
-
0033946796
-
-
(2000)
J. Med. Chem
, vol.43
, pp. 2297-2299
-
-
Rishton, G.M.1
Retz, D.M.2
Tempest, P.A.3
Novotny, J.4
Kahn, S.5
Treanor, J.J.S.6
Lile, J.D.7
Citron, M.8
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